IRAK1/4 Inhibitor I

Catalog # Availability Size / Price Qty
5665/10
5665/50
IRAK1/4 Inhibitor I | CAS No. 509093-47-4 | IRAK Inhibitors
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Description: IRAK4 and IRAK1 inhibitor

Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).

Technical Data

M.Wt:
395.41
Formula:
C20H21N5O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
509093-47-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
    Powers et al.
    Bioorg.Med.Chem.Lett., 2006;16:2842
  2. Bcl10 Regulates Lipopolysaccharide-Induced Pro-Fibrotic Signaling in Bronchial Fibroblasts from Severe Asthma Patients
    RK Ramakrishn, K Bajbouj, M Guimei, SS Rawat, Z Kalaji, MY Hachim, B Mahboub, SM Ibrahim, R Hamoudi, R Halwani, Q Hamid
    Biomedicines, 2022;10(7):.

Product Datasheets

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Citation for IRAK1/4 Inhibitor I

The citations listed below are publications that use Tocris products. Selected citations for IRAK1/4 Inhibitor I include:

1 Citation: Showing 1 - 1

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