Indomethacin

Catalog # Availability Size / Price Qty
1708/100
Indomethacin | CAS No. 53-86-1 | Cyclooxygenase Inhibitors
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Description: Cyclooxygenase inhibitor (COX-1 > COX-2)

Chemical Name: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole

Purity: ≥98%

Product Details
Citations (6)
Reviews

Biological Activity

Indomethacin is a cyclooxgenase (COX) inhibitor; displays selectivity for COX-1 (IC50 values are 230 and 630 nM for human COX-1 and COX-2 respectively). Widely used anti-inflammatory agent. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.

Technical Data

M.Wt:
357.79
Formula:
C19H16ClNO4
Solubility:
Soluble to 50 mM in ethanol with gentle warming and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
53-86-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Indomethacin

The citations listed below are publications that use Tocris products. Selected citations for Indomethacin include:

6 Citations: Showing 1 - 6

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