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IND 1316

Catalog #: 7685 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7685/10
7685/50
IND 1316 | CAS No. 1888473-12-8 | AMPK Activators
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Description: AMPK activator

Chemical Name: 3-[3-(Phenylmethoxy)phenyl]-1H-indole-2-carboxylic acid

Purity: ≥98%

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Biological Activity

IND 1316 is an activator of AMP-activated protein kinase (AMPK). In vitro, it activates AMPK in a dose-dependent manner and induces different MAPK pathways (p38 and JNK). In vivo, it reduces the neuropathological symptoms in two animal models of Huntington's Disease (nematodes and mice). It shows very low toxicity even at high concentrations (>200 μM). This compound is orally bioavailable.

Technical Data

M.Wt:
343.38
Formula:
C22H17NO3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1888473-12-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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