Human Wnt-8a (NP_490645.1) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC3677
Human Wnt-8a (NP_490645.1) VersaClone cDNA
1 Image
Product Details
FAQs
Reviews

Human Wnt-8a (NP_490645.1) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Product Datasheets

You must select a language.

x

Background: Wnt-8a

Wnt-8a is a secreted glycoprotein that binds to receptors of the Frizzled family. Wnt-8a is expressed during early optic lens development and cardiac myogenesis. The expression of Wnt-8a has also been shown to be upregulated during primitive hematopoiesis. TGF-beta has been shown to increase Wnt-8a secretion during epithelial mesenchymal transition (EMT).

The Wnts make up a large family of secreted proteins with roles in pattern formation, cell fate decision, axon guidance, and tumor formation. Wnt family members vary in length between 350 and 400 amino acids (aa), possess 22 to 24 conserved cysteines, are highly hydrophobic, and show 20 - 85% aa identity within the Wnt family. In general, there are three signaling pathways associated with Wnt-receptor interaction. The first is commonly called the canonical pathway and ultimately culminates in beta-Catenin accumulation and TCF/LEF-1-mediated gene transcription. The other two less well-defined non-canonical pathways include the Wnt/Ca2+ pathway and the planar cell polarity (PCP) pathway.

Long Name
Wingless-type MMTV Integration Site Family, Member 8a
Entrez Gene IDs
7478 (Human); 20890 (Mouse)
Alternate Names
protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family, member 8A; Wnt8a; Wnt-8a; WNT8DWNT8d

FAQs

No product specific FAQs exist for this product, however you may

View all cDNA Clone FAQs

Reviews for Human Wnt-8a (NP_490645.1) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human Wnt-8a (NP_490645.1) VersaClone cDNA and earn rewards!

Have you used Human Wnt-8a (NP_490645.1) VersaClone cDNA?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review