Human TGF-beta RII PerCP-conjugated Antibody

Catalog #: FAB241C Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB241C-100
FAB241C-025

Detection of TGF-beta RII in NS0 Mouse Cell Line Transfected with TGF-beta RII by Flow Cytometry.

1 Image

All TGF-beta RII Antibodies

Product Details

Supplemental Products

Reviews

Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TGF-beta RII PerCP-conjugated Antibody Summary

Species Reactivity

Human

Specificity

This antibody has been validated by flow cytometry on TGF-beta RII-transfected cells only. In contrast to Catalog # FAB2411A, minimal staining of PBMC lymphocytes was observed with this antibody.

Source

Monoclonal Mouse IgG₁ Clone # 25508

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human TGF-beta RII
Ile24-Asp159
Accession # P37173.2

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

PerCP (Peridinin-chlorophyll Protein Complex) (Excitation= 482 and 564 nm, Emission= 675 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

View Larger

Detection of TGF-beta RII in NS0 Mouse Cell Line Transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PerCP-conjugated Monoclonal Antibody (Catalog # FAB241C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: TGF-beta RII

TGF-beta RII is a membrane bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described.

Long Name

Transforming Growth Factor beta Receptor II

Entrez Gene IDs

7048 (Human); 21813 (Mouse)

Alternate Names

AAT3; EC 2.7.11; EC 2.7.11.30; FAA3; HNPCC6; LDS1B; LDS2B; MFS2; RIIC; TAAD2; tbetaR-II; TGF-beta receptor type II; TGF-beta receptor type IIB; TGF-beta receptor type-2; TGF-beta RII; TGF-beta type II receptor; TGFbetaRII; TGFbeta-RII; TGFBR2; TGF-bRII; TGFR-2; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor, beta receptor II (70-80kD); Transforming growth factor-beta receptor type II