Human Stanniocalcin 1/STC-1 Biotinylated Antibody

Catalog #: BAF2958 Datasheet / COA / SDS

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BAF2958

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Stanniocalcin 1/STC-1 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Stanniocalcin 1/STC-1 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human STC2 and recombinant mouse STC2 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Stanniocalcin 1/STC-1
Thr18-Ala247
Accession # P52823

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human Stanniocalcin 1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Stanniocalcin 1/STC-1

Human STC-1 is a secreted disulfide-linked homodimeric phosphorylated glycoprotein hormone (50 kDa and higher molecular weight variants) that is related to the STC protein first discovered from corpuscles of stannius in fish. It is expressed in a wide variety of tissues and has endocrine/paracrine/autocrine functions relating to calcium and phosphate homeostasis, reproduction and development. The 230 amino acid (aa) mature STC-1 contains five intrachain disulfide and one interchain disulfide bond. Human STC-1 and STC-2 share approximately 30% aa sequence homology. STC-1 is highly homologous across species. Human STC-1 shares > 95% sequence homology with mouse, rat, and bovine STC-1.

Entrez Gene IDs

6781 (Human)

Alternate Names

Stanniocalcin 1; stanniocalcin-1; STC1; STC-1; STCSTC-1