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Human SOX9 Antibody

Catalog #: AF3075
145 Citations 4 Reviews Datasheet / COA / SDS
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AF3075
AF3075-SP
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Detection of Human SOX9 by Western Blot.
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Citations (145)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SOX9 Antibody Summary

Species Reactivity
Human
Specificity
Detects human SOX9 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human SOX10 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human SOX9
Met1-Lys151
Accession # P48436
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.5 µg/mL
See below
Simple Western
20 µg/mL
See below
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human SOX9 antibody by Western Blot. View Larger

Detection of Human SOX9 by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, KATO-III human gastric carcinoma cell line, COLO 205 human colorectal adenocarcinoma cell line, and Hep3B human hepatocellular carcinoma cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human SOX9 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3075) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for SOX9 at approximately 75 kDa (as indicated). GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunocytochemistry SOX9 antibody in HEK293 Human Cell Line by Immunocytochemistry (ICC). View Larger

SOX9 in HEK293 Human Cell Line. SOX9 was detected in immersion fixed HEK293 human embryonic kidney cell line using 10 µg/mL Human SOX9 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3075) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunocytochemistry SOX9 antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC). View Larger

SOX9 in BG01V Human Embryonic Stem Cells. SOX9 was detected in immersion fixed BG01V human embryonic stem cells differentiated into early proximal lung progenitor cells using Goat Anti-Human SOX9 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3075) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; NL001) and counterstained with DAPI (blue, lower panel). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Simple Western Detection of Human SOX9 antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Human SOX9 by Simple WesternTM. Simple Western lane view shows lysates of normal adjacent tissue and Crohns tissue, loaded at 0.2 mg/mL. A specific band was detected for SOX9 at approximately 107 kDa (as indicated) using 20 µg/mL of Goat Anti-Human SOX9 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3075) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF019). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Western Blot Detection of Mouse SOX9 by Western Blot View Larger

Detection of Mouse SOX9 by Western Blot Comparison of E12.5 Sox9IE/IE and Sox9FE/FE embryos based on EGFP intensity and Western blotting.(A) Left panel: white light images of E12.5 Sox9IE/IE and Sox9FE/FE embryos; right panel: same embryos imaged by fluorescence microscopy showed a higher EGFP fluorescence in the Sox9FE/FE embryo compared to the Sox9IE/IE embryo, with EGFP expression in Sox9-specific domains in both. (B) Mean overall EGFP fluorescence of E12.5 Sox9IE/IE (13880.04±1015.55; n = 8) and Sox9FE/FE (84579.48±2822.09; n = 4) embryos analyzed by flow cytometry. Overall EGFP fluorescence was calculated by multiplying the MFI and percentage of EGFP-positive cells. Two-tailed Student's T test, ***p<0.0001. (C) Western blot analysis of E12.5 Sox9IE/IE and Sox9FE/FE embryo lysates, resolved on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) gels and immunoblotted with anti-Sox9 (upper panel) and anti-GFP (middle panel) antibodies. In the upper panel, Sox9-EGFP fusion protein and Sox9-2A (2A - residual 23 amino acids of F2A) was only detected in the Sox9FE/FE embryo lysate, but not in the CD-1 WT or Sox9IE/IE embryo lysates. Middle panel: Sox9-EGFP fusion protein was not detected in the Sox9FE/FE embryos but EGFP was detected in both the Sox9IE/IE and Sox9FE/FE lysates at predicted molecular weight. CD-1 WT lysate served as negative control for EGFP. Bottom panel: immunoblotting with anti-histone antibody showed equal loading. WT – wild-type. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0028885), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse SOX9 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse SOX9 by Immunocytochemistry/Immunofluorescence Dbx1‐expressing progenitors give rise to preBötC neurons and glia. A. Confocal images of Dbx1CreERT2; Rosa26tdTomato mouse preBötC sections immunostained for NeuN. Dbx1‐derived neurons (white arrowhead) expressed tdTomato and were immunoreactive for NeuN. Dbx1‐derived glia (gray arrowhead) expressed tdTomato and were not immunoreactive for NeuN. B. Confocal images of Dbx1CreERT2; Rosa26tdTomato mouse preBötC sections 72 h after injection with AAV‐hSyn‐GFP. Dbx1‐derived non‐neuronal cells extend diffuse fibrils that are closely apposed to the outer surface of microvasculature (white arrows). C, Confocal images of Dbx1CreERT2; Rosa26tdTomato mouse preBötC sections immunostained for Sox9. Glia (gray arrowheads) were immunoreactive for Sox9. Dbx1‐derived neurons (white arrowhead) expressed tdTomato but were not immunoreactive for Sox9. Dbx1‐derived glia expressed tdTomato and were immunoreactive for Sox9 (see “overlay” panel). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28611151), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence Feeder-free expansion of SOX9+ BCs. (A) Immunostaining of SOX9+ BCs with anti-P63, anti-KRT5 and anti-SOX9 antibodies. (B) SOX9+ BCs in rugae of 3rd order human airway by anti-SOX9, anti-P63 and anti-CC10 immunostaining. Scale bar, 100 μm. (C) SOX9+ BCs in rugae of 3rd order human airway by anti-KI67 immunostaining. (D) BC colony cultured on feeder-free condition. (E) Karyotyping of cultured BCs. (F) qPCR showing alveolar and bronchial epithelium marker gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages. n = 3, biological replicates. Error bars, S.E.M. (G) qPCR showing progenitor cell marker (Krt5, P63 and SOX9) gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages. n = 3, biological replicates. Error bars, S.E.M. (H) Western blotting showing marker gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/proteincell/article/9/3/267/6760074), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence Transplantated SOX9+ BCs regenerate functional human lungin vivo. (A) Left, direct fluorescence image under stereomicroscope showing NOD-SCID mouse lung without (upper panel) or with (lower panel) GFP-labeled SOX9+ BC transplantation. Right, cryo-section and direct fluorescence imaging of transplanted GFP-labeled SOX9+ BCs in lung parenchyma. Scale bar, 100 μm. (B) Immunofluorescence imaging of transplanted GFP-labeled SOX9+ BCs in lung parenchyma with human specific Lamin A+C marker costaining. (C) Fully differentiated GFP+ cells lost SOX9 marker expression (arrowhead indicated). Scale bar, 10 μm. (D) Confocal image with human specific Lamin A+C immunostaining (HuLamin) showing regenerated type I (AQP5+) alveolar cells. No type II (SPC+) cells were observed. (E) Confocal image showing regenerated AEC1 (AQP5+ and HOPX+). AQP5 as a membrane-bound protein distributes on surface of GFP+ cells. Arrowheads indicated the overlay of HOPX with GFP signal in nucleus. Scale bar, 20 μm. (F) qPCR with human specific primers showing alveolar and bronchiolar epithelium marker gene expression in SOX9+ BC transplanted chimeric lung (AEC1: AQP5 and HOPX; AEC2: SPB and LAMP3; bronchiolar cells: SCGB1A1 and MUC1). Biological replicates, n = 3. Error bars, S.E.M. (G) Left, clonogenic BCs isolated from human cervix epithelium obtained by biopsy. Right, transplantation of equal numbers of BCs from lung and cervix indicated different incorporation efficiency Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/proteincell/article/9/3/267/6760074), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence Feeder-free expansion of SOX9+ BCs. (A) Immunostaining of SOX9+ BCs with anti-P63, anti-KRT5 and anti-SOX9 antibodies. (B) SOX9+ BCs in rugae of 3rd order human airway by anti-SOX9, anti-P63 and anti-CC10 immunostaining. Scale bar, 100 μm. (C) SOX9+ BCs in rugae of 3rd order human airway by anti-KI67 immunostaining. (D) BC colony cultured on feeder-free condition. (E) Karyotyping of cultured BCs. (F) qPCR showing alveolar and bronchial epithelium marker gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages. n = 3, biological replicates. Error bars, S.E.M. (G) qPCR showing progenitor cell marker (Krt5, P63 and SOX9) gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages. n = 3, biological replicates. Error bars, S.E.M. (H) Western blotting showing marker gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/proteincell/article/9/3/267/6760074), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Human SOX9 by Immunocytochemistry/Immunofluorescence Feeder-free expansion of SOX9+ BCs. (A) Immunostaining of SOX9+ BCs with anti-P63, anti-KRT5 and anti-SOX9 antibodies. (B) SOX9+ BCs in rugae of 3rd order human airway by anti-SOX9, anti-P63 and anti-CC10 immunostaining. Scale bar, 100 μm. (C) SOX9+ BCs in rugae of 3rd order human airway by anti-KI67 immunostaining. (D) BC colony cultured on feeder-free condition. (E) Karyotyping of cultured BCs. (F) qPCR showing alveolar and bronchial epithelium marker gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages. n = 3, biological replicates. Error bars, S.E.M. (G) qPCR showing progenitor cell marker (Krt5, P63 and SOX9) gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages. n = 3, biological replicates. Error bars, S.E.M. (H) Western blotting showing marker gene expression of human lung sample and SOX9+ BCs in early (P2) and late (P8) passages Image collected and cropped by CiteAb from the following publication (https://academic.oup.com/proteincell/article/9/3/267/6760074), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX9

SOX9 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX9 is expressed in mesenchymal progenitors that give rise to chondrocytes and osteoblasts. It is also expressed in the central nervous system, neural crest, intestine, pancreas, and testis. Mutations in SOX9 are associated with defects in sex determination, cartilage and bone development, as well as abnormalities of the heart, kidneys, brain, gut, and pancreas.

Long Name
Transcription Factor SOX9
Entrez Gene IDs
6662 (Human)
Alternate Names
campomelic dysplasia, autosomal sex-reversal; CMD 1; CMD1; CMPD1; SOX9; SRA1SRY (sex-determining region Y)-box 9 protein; SRY (sex determining region Y)-box 9; SRY-related HMG-box, gene 9; transcription factor SOX-9

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Citations for Human SOX9 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

145 Citations: Showing 1 - 10
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  1. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice
    Authors: O'Shea TM, Ao Y, Wang S et al.
    Nature Communications
  2. A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids
    Authors: Briana R Dye, Priya H Dedhia, Alyssa J Miller, Melinda S Nagy, Eric S White, Lonnie D Shea et al.
    eLife
  3. Protocol for the purification and transcriptomic analysis of mouse astrocytes using GFAT
    Authors: Lara Labarta-Bajo, James Deng, Minerva Contreras, Nicola J. Allen
    STAR Protoc
  4. Anabolic phenotype in cartilage-specific mitogen-inducible gene-6 knockout mice is independent of transforming growth factor-alpha
    Authors: Ermina Hadzic, Bethia To, Michael A. Pest, Ling Qin, Frank Beier
    Osteoarthritis and Cartilage Open
  5. Generation of Complete Multi−Cell Type Lung Organoids From Human Embryonic and Patient‐Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation
    Authors: Sandra L. Leibel, Rachael N. McVicar, Alicia M. Winquist, Walter D. Niles, Evan Y. Snyder
    Current Protocols in Stem Cell Biology
  6. Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood
    Authors: Nora Hagemeyer, Klara-Maria Hanft, Maria-Anna Akriditou, Nicole Unger, Eun S. Park, E. Richard Stanley et al.
    Acta Neuropathologica
  7. Gene expression profiles of Bapx1 expressing FACS sorted cells from wildtype and Bapx1-EGFP null mouse embryos
    Authors: Sumantra Chatterjee, V. Sivakamasundari, Petra Kraus, Sook Peng Yap, Vibhor Kumar, Shyam Prabhakar et al.
    Genomics Data
  8. Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model
    Authors: Zhenqing Liu, Jianfei Chao, Cheng Wang, Guihua Sun, Daniel Roeth, Wei Liu et al.
    Cell Reports
  9. The Structure of the Spinal Cord Ependymal Region in Adult Humans Is a Distinctive Trait among Mammals
    Authors: Alejandro Torrillas de la Cal, Beatriz Paniagua-Torija, Angel Arevalo-Martin, Christopher Guy Faulkes, Antonio Jesús Jiménez, Isidre Ferrer et al.
    Cells
  10. Efficient and Controlled Generation of 2D and 3D Bile Duct Tissue from Human Pluripotent Stem Cell-Derived Spheroids
    Authors: Lipeng Tian, Abhijeet Deshmukh, Zhaohui Ye, Yoon-Young Jang
    Stem Cell Reviews and Reports
  11. Morphology and development of a novel murine skeletal dysplasia
    Authors: Marta Marchini, Elizabeth Silva Hernandez, Campbell Rolian
    PeerJ
  12. The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts
    Authors: Joshua D. Currie, Lidia Grosser, Prayag Murawala, Maritta Schuez, Martin Michel, Elly M. Tanaka et al.
    Biology Open
  13. R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development
    Authors: Renee F.C. Hein, Joshua H. Wu, Emily M. Holloway, Tristan Frum, Ansley S. Conchola, Yu-Hwai Tsai et al.
    Developmental Cell
  14. Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity
    Authors: Akitoshi Hara, Katsuhiro Kato, Toshikazu Ishihara, Hiroki Kobayashi, Naoya Asai, Shinji Mii et al.
    Genes to Cells
  15. Choline kinase beta is required for normal endochondral bone formation
    Authors: Zhuo Li, Gengshu Wu, Roger B. Sher, Zohreh Khavandgar, Martin Hermansson, Gregory A. Cox et al.
    Biochimica et Biophysica Acta (BBA) - General Subjects
  16. Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells
    Authors: Rore H, Owen N, Pina-Aguilar Re Et Al.
    Communications biology
  17. A new genetic strategy for targeting microglia in development and disease
    Authors: McKinsey GL, Lizama CO, Keown-Lang AE et al.
    Elife
  18. Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
    Authors: Isabel Stüfchen, Felix Beyer, Sebastian Staebler, Stefan Fischer, Melanie Kappelmann, Ruth Beckervordersandforth et al.
    iScience
  19. Charting human development using a multi-endodermal organ atlas and organoid models
    Authors: Qianhui Yu, Umut Kilik, Emily M. Holloway, Yu-Hwai Tsai, Christoph Harmel, Angeline Wu et al.
    Cell
  20. An Investigation Into the Role of Osteocalcin in Human Arterial Smooth Muscle Cell Calcification
    Authors: Sophie A. Millar, Stephen G. John, Christopher W. McIntyre, Vera Ralevic, Susan I. Anderson, Saoirse E. O'Sullivan
    Front Endocrinol (Lausanne)
  21. Generation of human embryonic stem cell-derived lung organoids
    Authors: Le Han, Shanshan Zhao, Fuxun Yu, Zhili Rong, Ying Lin, Yong Chen
    STAR Protocols
  22. Primary Cilia Direct Murine Articular Cartilage Tidemark Patterning Through Hedgehog Signaling and Ambulatory Load
    Authors: Danielle Rux, Kimberly Helbig, Biao Han, Courtney Cortese, Eiki Koyama, Lin Han et al.
    Journal of Bone and Mineral Research
  23. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities
    Authors: Anna Yu-Szu Huang, Junsung Woo, Debosmita Sardar, Brittney Lozzi, Navish A Bosquez Bosquez Huerta, Chia-Ching John Lin et al.
    Neuron
  24. Mutant Lef1 controls Gata6 in sebaceous gland development and cancer
    Authors: Bénédicte Oulès, Emanuel Rognoni, Esther Hoste, Georgina Goss, Ryan Fiehler, Ken Natsuga et al.
    The EMBO Journal
  25. Fibroblast dedifferentiation as a determinant of successful regeneration
    Authors: Tzi-Yang Lin, Tobias Gerber, Yuka Taniguchi-Sugiura, Prayag Murawala, Sarah Hermann, Lidia Grosser et al.
    Developmental Cell
  26. In vitro models of fetal lung development to enhance research into congenital lung diseases
    Authors: Soichi Shibuya, Jessica Allen-Hyttinen, Paolo De Coppi, Federica Michielin
    Pediatric Surgery International
  27. beta -catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis
    Authors: Vladimir Ustiyan, Yufang Zhang, Anne-Karina T. Perl, Jeffrey A. Whitsett, Tanya V. Kalin, Vladimir V. Kalinichenko
    Developmental Dynamics
  28. Intersections between Regulated Cell Death and Autophagy
    Authors: Francesco Napoletano, Olga Baron, Peter Vandenabeele, Bertrand Mollereau, Manolis Fanto
    Trends in Cell Biology
  29. NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development
    Authors: Dorien Baetens, Hans Stoop, Frank Peelman, Anne-Laure Todeschini, Toon Rosseel, Frauke Coppieters et al.
    Genetics in Medicine
  30. Sequential perturbations to mouse corticogenesis following in utero maternal immune activation
    Authors: Cesar P Canales, Myka L Estes, Karol Cichewicz, Kartik Angara, John Paul Aboubechara, Scott Cameron et al.
    eLife
  31. Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair
    Authors: Gupta N, Matsumoto T, Hiratsuka K et al.
    Science Translational Medicine
  32. Primate cell fusion disentangles gene regulatory divergence in neurodevelopment
    Authors: RM Agoglia, D Sun, F Birey, SJ Yoon, Y Miura, K Sabatini, SP Pa?ca, HB Fraser
    Nature, 2021-03-17;0(0):.
  33. Wnts Are Expressed in the Spinal Cord of Adult Mice and Are Differentially Induced after Injury
    Authors: Carlos González-Fernández, Carmen María Fernández-Martos, Shannon D. Shields, Ernest Arenas, Francisco Javier Rodríguez
    Journal of Neurotrauma
  34. Digits in a dish: An in vitro system to assess the molecular genetics of hand/foot development at single-cell resolution
    Authors: Allison M. Fuiten, Yuki Yoshimoto, Chisa Shukunami, H. Scott Stadler
    Frontiers in Cell and Developmental Biology
  35. Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes
    Authors: Chen Jin, Yayu Wu, Haipeng Zhang, Bai Xu, Wenbin Liu, Chunnan Ji et al.
    Bioengineering & Translational Medicine
  36. YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma
    Authors: Krishanthan Vigneswaran, Nathaniel H. Boyd, Se-Yeong Oh, Shoeb Lallani, Andrew Boucher, Stewart G. Neill et al.
    Clinical Cancer Research
  37. Periosteal Mesenchymal Progenitor Dysfunction and Extraskeletally‐Derived Fibrosis Contribute to Atrophic Fracture Nonunion
    Authors: Luqiang Wang, Robert J Tower, Abhishek Chandra, Lutian Yao, Wei Tong, Zekang Xiong et al.
    Journal of Bone and Mineral Research
  38. Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis
    Authors: Wenguang Yin, Hyun-Taek Kim, ShengPeng Wang, Felix Gunawan, Rui Li, Carmen Buettner et al.
    European Respiratory Journal
  39. Genetic Dissection of BDNF and TrkB Expression in Glial Cells
    Authors: Niu, C;Yue, X;An, JJ;Bass, R;Xu, H;Xu, B;
    Biomolecules
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  40. CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair
    Authors: Hassan, D;Chen, J;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  41. Astrocytic ?-catenin signaling via TCF7L2 regulates synapse development and social behavior
    Authors: Szewczyk, LM;Lipiec, MA;Liszewska, E;Meyza, K;Urban-Ciecko, J;Kondrakiewicz, L;Goncerzewicz, A;Rafalko, K;Krawczyk, TG;Bogaj, K;Vainchtein, ID;Nakao-Inoue, H;Puscian, A;Knapska, E;Sanders, SJ;Jan Nowakowski, T;Molofsky, AV;Wisniewska, MB;
    Molecular psychiatry
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  42. Genetic dissection of BDNF and TrkB expression in glial cells
    Authors: Niu, C;Yue, X;An, JJ;Xu, H;Xu, B;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. A distal lung organoid model to study interstitial lung disease, viral infection and human lung development
    Authors: Matkovic Leko, I;Schneider, RT;Thimraj, TA;Schrode, N;Beitler, D;Liu, HY;Beaumont, K;Chen, YW;Snoeck, HW;
    Nature protocols
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  44. Prenatal triclosan exposure impairs mammalian lung branching morphogenesis through activating Bmp4 signaling
    Authors: Q Li, Y Qiao, F Wang, J Zhao, L Wu, H Ge, S Xu
    Ecotoxicology and environmental safety, 2023-04-12;256(0):114896.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  45. Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation
    Authors: J Sun, S Osenberg, A Irwin, LH Ma, N Lee, Y Xiang, F Li, YW Wan, IH Park, M Maletic-Sa, N Ballas
    Cell Reports, 2023-01-05;42(1):111942.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  46. SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice
    Authors: Y Wang, S Zhang, Z Lan, V Doan, B Kim, S Liu, M Zhu, VL Hull, S Rihani, CL Zhang, JA Gray, F Guo
    Cell Reports, 2022-12-20;41(12):111842.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  47. mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity
    Authors: K Zhang, E Yao, E Chuang, B Chen, EY Chuang, PT Chuang
    Nature Communications, 2022-11-25;13(1):7252.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  48. Maturation and circuit integration of transplanted human cortical organoids
    Authors: O Revah, F Gore, KW Kelley, J Andersen, N Sakai, X Chen, MY Li, F Birey, X Yang, NL Saw, SW Baker, ND Amin, S Kulkarni, R Mudipalli, B Cui, S Nishino, GA Grant, JK Knowles, M Shamloo, JR Huguenard, K Deisseroth, SP Pa?ca
    Nature, 2022-10-12;610(7931):319-326.
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: ICC
  49. WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome
    Authors: Y Tian, W Wang, S Lautrup, H Zhao, X Li, PWN Law, ND Dinh, EF Fang, HH Cheung, WY Chan
    Nature Communications, 2022-09-16;13(1):5456.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  50. Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions
    Authors: K Zhang, E Yao, E Chuang, B Chen, EY Chuang, RF Volk, KL Hofmann, B Zaro, PT Chuang
    PloS Biology, 2022-08-26;20(8):e3001759.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  51. SOX9 reprograms endothelial cells by altering the chromatin landscape
    Authors: BM Fuglerud, S Drissler, J Lotto, TL Stephan, A Thakur, R Cullum, PA Hoodless
    Nucleic Acids Research, 2022-08-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  52. SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis
    Authors: E Place, E Manning, DW Kim, A Kinjo, G Nakamura, K Ohyama
    Frontiers in Neuroscience, 2022-08-11;16(0):855288.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: ICC/IF
  53. Divergent transcriptional regulation of astrocyte reactivity across disorders
    Authors: JE Burda, TM O'Shea, Y Ao, KB Suresh, S Wang, AM Bernstein, A Chandra, S Deverasett, R Kawaguchi, JH Kim, S McCallum, A Rogers, S Wahane, MV Sofroniew
    Nature, 2022-05-25;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  54. Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis
    Authors: R Belgacemi, S Danopoulos, G Deutsch, I Glass, V Dormoy, S Bellusci, D Al Alam
    International Journal of Molecular Sciences, 2022-05-09;23(9):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  55. The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development
    Authors: T Gu, D Hao, J Woo, TW Huang, L Guo, X Lin, AG Guzman, A Tovy, C Rosas, M Jeong, Y Zhou, B Deneen, Y Huang, W Li, MA Goodell
    Nature Genetics, 2022-05-09;54(5):625-636.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  56. Specification of CNS macrophage subsets occurs postnatally in defined niches
    Authors: T Masuda, L Amann, G Monaco, R Sankowski, O Staszewski, M Krueger, F Del Gaudio, L He, N Paterson, E Nent, F Fernández-, A Yamasaki, M Frosch, M Fliegauf, LFP Bosch, H Ulupinar, N Hagemeyer, D Schreiner, C Dorrier, M Tsuda, C Grothe, A Joutel, R Daneman, C Betsholtz, U Lendahl, KP Knobeloch, T Lämmermann, J Priller, K Kierdorf, M Prinz
    Nature, 2022-04-20;604(7907):740-748.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. Age and Alzheimer's Disease-Related Oligodendrocyte Changes in Hippocampal Subregions
    Authors: L DeFlitch, E Gonzalez-F, I Crawley, SH Kang
    Frontiers in Cellular Neuroscience, 2022-04-07;16(0):847097.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  58. Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm
    Authors: R Roldán-Mon, JM Pérez-Sáez, I Cerro-Pard, J Oller, D Martinez-L, E Nuñez, SM Maller, C Gutierrez-, N Mendez-Bar, JC Escola-Gil, JB Michel, M Mittelbrun, J Vázquez, LM Blanco-Col, GA Rabinovich, JL Martin-Ven
    Science Advances, 2022-03-16;8(11):eabm7322.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  59. Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting
    Authors: AE Lewis, A Kuwahara, J Franzosi, JO Bush
    Cell Reports, 2022-03-15;38(11):110510.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  60. Localized astrogenesis regulates gyrification of the cerebral cortex
    Authors: Y Shinmyo, K Saito, T Hamabe-Hor, N Kameya, A Ando, K Kawasaki, TAD Duong, M Sakashita, J Roboon, T Hattori, T Kannon, K Hosomichi, M Slezak, MG Holt, A Tajima, O Hori, H Kawasaki
    Science Advances, 2022-03-11;8(10):eabi5209.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  61. Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia
    Authors: T Xu, X Li, Y Guo, E Uhlin, L Holmberg, S Mitra, D Winn, A Falk, E Sundström
    EBioMedicine, 2022-02-16;77(0):103882.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  62. Suspension culture promotes serosal mesothelial development in human intestinal organoids
    Authors: MM Capeling, S Huang, CJ Childs, JH Wu, YH Tsai, A Wu, N Garg, EM Holloway, N Sundaram, C Bouffi, M Helmrath, JR Spence
    Cell Reports, 2022-02-15;38(7):110379.
    Species: Human
    Sample Types: Organoids
    Applications: IHC
  63. Induction of osteogenesis by bone-targeted Notch activation
    Authors: C Xu, VV Dinh, K Kruse, HW Jeong, EC Watson, S Adams, F Berkenfeld, M Stehling, SJ Rasouli, R Fan, R Chen, I Bedzhov, Q Chen, K Kato, ME Pitulescu, RH Adams
    Elife, 2022-02-04;11(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus
    Authors: B Potier, L Lallemant, S Parrot, A Huguet-Lac, G Gourdon, P Dutar, M Gomes-Pere
    International Journal of Molecular Sciences, 2022-01-06;23(2):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration
    Authors: AH Cleveland, A Romero-Mor, LA Azcona, M Herrero, VD Nikolova, S Moy, O Elroy-Stei, V Gama, TR Gershon
    Cell Death & Disease, 2021-12-06;12(12):1133.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  66. IL-33 induces orofacial neuropathic pain through Fyn-dependent phosphorylation of GluN2B in the trigeminal spinal nucleus caudalis
    Authors: Y Kimura, Y Hayashi, S Hitomi, D Ikutame, K Urata, I Shibuta, A Sakai, J Ni, K Iwata, M Tonogi, M Shinoda
    Brain, Behavior, and Immunity, 2021-10-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  67. Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
    Authors: M Lattke, R Goldstone, JK Ellis, S Boeing, J Jurado-Arj, N Marichal, JI MacRae, B Berninger, F Guillemot
    Nature Communications, 2021-07-15;12(1):4335.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  68. GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration
    Authors: RR Khawaja, A Agarwal, M Fukaya, HK Jeong, S Gross, E Gonzalez-F, J Soboloff, DE Bergles, SH Kang
    Cell Reports, 2021-05-18;35(7):109147.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  69. Orchestrated cellular, biochemical, and biomechanical optimizations endow platelet-rich plasma-based engineered cartilage with structural and biomechanical recovery
    Authors: K Wang, J Li, Y Wang, Y Wang, Y Qin, F Yang, M Zhang, H Zhu, Z Li
    Bioactive materials, 2021-04-10;6(11):3824-3838.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  70. Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury
    Authors: C Gong, X Zheng, F Guo, Y Wang, S Zhang, J Chen, X Sun, SZA Shah, Y Zheng, X Li, Y Yin, Q Li, X Huang, T Guo, X Han, SC Zhang, W Wang, H Chen
    Cell Reports, 2021-03-23;34(12):108889.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  71. Long-term maturation of human cortical organoids matches key early postnatal transitions
    Authors: A Gordon, SJ Yoon, SS Tran, CD Makinson, JY Park, J Andersen, AM Valencia, S Horvath, X Xiao, JR Huguenard, SP Pa?ca, DH Geschwind
    Nature Neuroscience, 2021-02-22;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  72. ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
    Authors: C Wang, M Zhang, G Garcia, E Tian, Q Cui, X Chen, G Sun, J Wang, V Arumugaswa, Y Shi
    Cell Stem Cell, 2021-01-04;28(2):331-342.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  73. Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk
    Authors: SE Howden, SB Wilson, E Groenewege, L Starks, TA Forbes, KS Tan, JM Vanslambro, EM Holloway, YH Chen, S Jain, JR Spence, MH Little
    Cell Stem Cell, 2020-12-29;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  74. ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia
    Authors: AN Gonçalves, J Correia-Pi, C Nogueira-S
    Respir Res, 2020-11-18;21(1):302.
    Species: Rat
    Sample Types: Whole Cells, Whole Tissue
    Applications: IHC, Western Blot
  75. Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis
    Authors: B Oulès, C Philippeos, J Segal, M Tihy, M Vietri Rud, AM Cujba, PA Grange, S Quist, K Natsuga, L Deschamps, N Dupin, G Donati, FM Watt
    Nat Commun, 2020-10-20;11(1):5067.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  76. DSCAM regulates delamination of neurons in the developing midbrain
    Authors: N Arimura, M Okada, S Taya, KI Dewa, A Tsuzuki, H Uetake, S Miyashita, K Hashizume, K Shimaoka, S Egusa, T Nishioka, Y Yanagawa, K Yamakawa, YU Inoue, T Inoue, K Kaibuchi, M Hoshino
    Science Advances, 2020-09-02;6(36):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  77. Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors
    Authors: E Roy, HY Wong, R Villani, T Rouille, B Salik, SL Sim, V Murigneux, MS Stark, JL Fink, HP Soyer, G Walker, JG Lyons, N Saunders, K Khosrotehr
    Cell Rep, 2020-06-02;31(9):107702.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  78. Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice
    Authors: M Bellini, MA Pest, M Miranda-Ro, L Qin, JW Jeong, F Beier
    Arthritis Res. Ther., 2020-05-19;22(1):119.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  79. Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors
    Authors: KN Gerner-Mau, H Akiyama, J Chen
    Proc. Natl. Acad. Sci. U.S.A., 2020-05-15;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  80. Differential Proliferation and Maturation of Subcortical Astrocytes During Postnatal Development
    Authors: T Shoneye, AT Orrego, R Jarvis, Y Men, MSR Chiang, Y Yang
    Front Neurosci, 2020-05-08;14(0):435.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  81. Embryonic microglia influence developing hypothalamic glial populations
    Authors: CM Marsters, D Nesan, R Far, N Klenin, QJ Pittman, DM Kurrasch
    J Neuroinflammation, 2020-05-06;17(1):146.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  82. Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone
    Authors: KL Adams, G Riparini, P Banerjee, M Breur, M Bugiani, V Gallo
    Nat Commun, 2020-05-01;11(1):2138.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  83. iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation
    Authors: A Fleischer, S Vallejo-Dí, JM Martín-Fer, A Sánchez-Gi, M Castresana, A Del Pozo, A Esquisabel, S Ávila, JL Castrillo, E Gaínza, JL Pedraz, M Viñas, D Bachiller
    Mol Ther Methods Clin Dev, 2020-04-18;17(0):858-870.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  84. Injured adult neurons regress to an embryonic transcriptional growth state
    Authors: GHD Poplawski, R Kawaguchi, E Van Nieker, P Lu, N Mehta, P Canete, R Lie, I Dragatsis, JM Meves, B Zheng, G Coppola, MH Tuszynski
    Nature, 2020-04-15;581(7806):77-82.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  85. Gut Microbiota Modulate CD8�T Cell Responses to Influence Colitis-Associated Tumorigenesis
    Authors: AI Yu, L Zhao, KA Eaton, S Ho, J Chen, S Poe, J Becker, A Gonzalez, D McKinstry, M Hasso, J Mendoza-Ca, J Whitfield, C Koumpouras, PD Schloss, EC Martens, GY Chen
    Cell Rep, 2020-04-07;31(1):107471.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  86. Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis
    Authors: L Besse, CJ Sheeba, M Holt, M Labuhn, S Wilde, E Feneck, D Bell, A Kucharska, MPO Logan
    Cell Rep, 2020-03-10;30(10):3552-3565.e6.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  87. Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration
    Authors: T Yuan, K Klinkhamme, H Lyu, S Gao, J Yuan, S Hopkins, JS Zhang, SP De Langhe
    Front Pharmacol, 2020-03-02;11(0):120.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  88. Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
    Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
    Dis Model Mech, 2019-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  89. Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo
    Authors: S Biswas, SH Chung, P Jiang, S Dehghan, W Deng
    Sci Rep, 2019-06-21;9(1):9013.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  90. Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue
    Authors: OC Tysoe, AW Justin, T Brevini, SE Chen, KT Mahbubani, AK Frank, H Zedira, E Melum, K Saeb-Parsy, AE Markaki, L Vallier, F Sampazioti
    Nat Protoc, 2019-05-20;14(6):1884-1925.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  91. Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation
    Authors: SG Romeo, KM Alawi, J Rodrigues, A Singh, AP Kusumbe, SK Ramasamy
    Nat. Cell Biol., 2019-04-01;21(4):430-441.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  92. Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion
    Authors: MJ Castle, Y Cheng, A Asokan, MH Tuszynski
    Sci Adv, 2018-11-14;4(11):eaau9859.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  93. Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
    Authors: JR Jones, L Kong, MG Hanna, B Hoffman, R Krencik, R Bradley, T Hagemann, J Choi, M Doers, M Dubovis, MA Sherafat, A Bhattachar, C Kendziorsk, A Audhya, A Messing, SC Zhang
    Cell Rep, 2018-10-23;25(4):947-958.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  94. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
    Cell Stem Cell, 2018-09-20;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  95. Complex bile duct network formation within liver decellularized extracellular matrix hydrogels
    Authors: PL Lewis, J Su, M Yan, F Meng, SS Glaser, GD Alpini, RM Green, B Sosa-Pined, RN Shah
    Sci Rep, 2018-08-15;8(1):12220.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  96. In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus
    Authors: JM Rosin, DM Kurrasch
    J Neuroinflammation, 2018-06-12;15(1):181.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  97. Does human endometrial LGR5 gene expression suggest the existence of another hormonally regulated epithelial stem cell niche?
    Authors: N Tempest, AM Baker, NA Wright, DK Hapangama
    Hum. Reprod., 2018-06-01;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  98. Glutamate transporter Slc1a3 mediates inter-niche stem cell activation during skin growth
    Authors: B Reichenbac, J Classon, T Aida, K Tanaka, M Genander, C Göritz
    EMBO J., 2018-04-03;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  99. Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors
    Authors: II Aigha, B Memon, AK Elsayed, EM Abdelalim
    Stem Cell Res Ther, 2018-04-03;9(1):83.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  100. Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
    Authors: PR Tata, RD Chow, SV Saladi, A Tata, A Konkimalla, A Bara, D Montoro, LP Hariri, AR Shih, M Mino-Kenud, H Mou, S Kimura, LW Ellisen, J Rajagopal
    Dev. Cell, 2018-03-26;44(6):679-693.e5.
    Species: Human, Mouse
    Sample Types: Organoid, Whole Tissue
    Applications: IHC-Fr
  101. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells
    Authors: M Zhang, J Ngo, F Pirozzi, YP Sun, A Wynshaw-Bo
    Stem Cell Res Ther, 2018-03-15;9(1):67.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  102. Restorative effects of human neural stem cell grafts on the primate spinal cord
    Authors: ES Rosenzweig, JH Brock, P Lu, H Kumamaru, EA Salegio, K Kadoya, JL Weber, JJ Liang, R Moseanko, S Hawbecker, JR Huie, LA Havton, YS Nout-Lomas, AR Ferguson, MS Beattie, JC Bresnahan, MH Tuszynski
    Nat. Med., 2018-02-26;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  103. Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
    Authors: B Memon, M Karam, S Al-Khawaga, EM Abdelalim
    Stem Cell Res Ther, 2018-01-23;9(1):15.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  104. Meis1 coordinates cerebellar granule cell development by regulating Pax6 transcription, BMP signaling and Atoh1 degradation
    Authors: T Owa, S Taya, S Miyashita, M Yamashita, T Adachi, K Yamada, M Yokoyama, S Aida, T Nishioka, YU Inoue, R Goitsuka, T Nakamura, T Inoue, K Kaibuchi, M Hoshino
    J. Neurosci., 2018-01-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  105. Fate mapping neurons and glia derived from Dbx1-expressing progenitors in mouse preB�tzinger complex
    Authors: A Kottick, CA Martin, CA Del Negro
    Physiol Rep, 2017-06-01;5(11):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  106. An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos
    Authors: WJ Lee, S Chatterjee, SP Yap, SL Lim, X Xing, P Kraus, W Sun, X Hu, V Sivakamasu, HY Chan, PR Kolatkar, S Prabhakar, T Lufkin
    Biomed Res Int, 2017-05-28;2017(0):8932583.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ChIP
  107. SOX9 is an astrocyte-specific nuclear marker in the adult brain outside the neurogenic regions
    Authors: W Sun, A Cornwell, J Li, S Peng, MJ Osorio, NA Su Wanga, A Benraiss, N Lou, SA Goldman, M Nedergaard
    J. Neurosci, 2017-03-23;0(0):.
    Species: Human, Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC
  108. YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
    Authors: C Lin, E Yao, K Zhang, X Jiang, S Croll, K Thompson-P, PT Chuang
    Elife, 2017-03-21;6(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  109. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate
    Authors: Emma L Rawlins
    Development, 2016-08-30;143(20):3686-3699.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  110. The development and plasticity of alveolar type 1 cells
    Authors: J Yang, BJ Hernandez, D Martinez A, O Narvaez de, L Vila-Ellis, H Akiyama, SE Evans, EJ Ostrin, J Chen
    Development, 2015-11-19;143(1):54-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  111. Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans.
    Authors: Shojaie S, Ermini L, Ackerley C, Wang J, Chin S, Yeganeh B, Bilodeau M, Sambi M, Rogers I, Rossant J, Bear C, Post M
    Stem Cell Reports, 2015-02-05;4(3):419-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  112. In vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column.
    Authors: Chatterjee S, Sivakamasundari V, Yap S, Kraus P, Kumar V, Xing X, Lim S, Sng J, Prabhakar S, Lufkin T
    BMC Genomics, 2014-12-05;15(0):1072.
    Species: Mouse
    Sample Types: Chromatin
    Applications: ChIP
  113. Expression of SOX9 and CDX2 in nongoblet columnar-lined esophagus predicts the detection of Barrett's esophagus during follow-up.
    Authors: Zhang X, Westerhoff M, Hart J
    Mod Pathol, 2014-11-21;28(5):654-61.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  114. The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors.
    Authors: Mahoney J, Mori M, Szymaniak A, Varelas X, Cardoso W
    Dev Cell, 2014-07-17;30(2):137-50.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  115. Two nested developmental waves demarcate a compartment boundary in the mouse lung.
    Authors: Alanis, Denise M, Chang, Daniel R, Akiyama, Haruhiko, Krasnow, Mark A, Chen, Jichao
    Nat Commun, 2014-05-29;5(0):3923.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  116. Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.
    Authors: Ramasamy S, Kusumbe A, Wang L, Adams R
    Nature, 2014-03-12;507(7492):376-80.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  117. The vanishing testis: a histomorphologic and clinical assessment.
    Authors: Antic T, Hyjek EM, Taxy JB
    Am. J. Clin. Pathol., 2011-12-01;136(6):872-80.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  118. Identification of SOX3 as an XX male sex reversal gene in mice and humans.
    Authors: Sutton E, Hughes J, White S
    J. Clin. Invest., 2010-12-22;121(1):328-41.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  119. Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold.
    Authors: Cavallo C, Desando G, Facchini A, Grigolo B
    J Biomed Mater Res A, 2010-04-01;93(1):86-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  120. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines.
    Authors: Swartling FJ, Ferletta M, Kastemar M, Weiss WA, Westermark B
    Oncogene, 2009-06-22;28(35):3121-31.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  121. A Novel Approach for the Derivation of Putative Primordial Germ Cells and Sertoli Cells from Human Embryonic Stem Cells.
    Authors: Bucay N, Yebra M, Cirulli V, Afrikanova I, Kaido T, Hayek A, Montgomery AM
    Stem Cells, 2009-01-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  122. FOXL2 and SOX9 as parameters of female and male gonadal differentiation in patients with various forms of disorders of sex development (DSD).
    Authors: Hersmus R, Kalfa N, de Leeuw B, Stoop H, Oosterhuis JW, de Krijger R, Wolffenbuttel KP, Drop SL, Veitia RA, Fellous M, Jaubert F, Looijenga LH
    J. Pathol., 2008-05-01;215(1):31-8.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  123. Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice
    Authors: JM Delhove, SM Buckley, DP Perocheau, R Karda, P Arbuthnot, NC Henderson, SN Waddington, TR McKay
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  142. Dentate gyrus development requires a cortical hem-derived astrocytic scaffold
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Human SOX9 Antibody
By Anonymous on 07/14/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Embryo tissue Species: Mouse
Immunocytochemistry/Immunofluorescence Human SOX9 Antibody AF3075
Human SOX9 Antibody
By Chang Xie on 03/20/2019
Sample Tested: Embryonic lung Species: Mouse

PFA fixed, sectioned, PBS washed, treated for 5 min in cold Methanol. Worked great!

Human SOX9 Antibody
By Preethi Vijayaraj on 09/27/2017
Application: Immunocytochemistry/Immunofluorescence Sample Tested: iPSC differentiated epithelial cells Species: Human
Immunocytochemistry/Immunofluorescence Human SOX9 Antibody AF3075
Human SOX9 Antibody
By Anonymous on 12/15/2016
Application: Immunocytochemistry/Immunofluorescence Sample Tested: stem cells Species: Human

For immunohistochemistry & immunocytochemistry application.