Human SIRP gamma/CD172g (NP_061026) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1891
R&D Systems VersaClone cDNA Plasmids
1 Image
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Human SIRP gamma/CD172g (NP_061026) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: SIRP gamma/CD172g

Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a type I transmembrane protein belonging to the SIRP/SHPS (CD172) family within the Ig superfamily. SIRP gamma is expressed on T cells, CD56bright NK cells and activated NK cells, but not myeloid cells. Like SIRP alpha, it binds CD47, but unlike SIRP alpha, it does not contain an obvious signaling mechanism. T cell SIRP gamma may play a role as an accessory protein interacting with CD47-expressing antigen presenting cells, and appears to promote antigen-specific T cell proliferation and costimulate T cell activation.

Long Name
Signal-regulatory Protein gamma
Entrez Gene IDs
55423 (Human); 102138723 (Cynomolgus Monkey)
Alternate Names
bA77C3.1; CD172g antigen; CD172g; FLJ42230; signal-regulatory protein beta 2; Signal-regulatory protein beta-2; signal-regulatory protein gamma; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPB2CD172 antigen-like family member B; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma

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