Home / Serpin A8/Angiotensinogen / Human Serpin A8/Angiotensinogen Antibody

Human Serpin A8/Angiotensinogen Antibody

Catalog #: MAB3156
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB3156
MAB3156-SP
Product Details
Citations (5)
FAQs
Supplemental Products
Reviews
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Serpin A8/Angiotensinogen Antibody Summary

Species Reactivity
Human
Specificity
Detects human Serpin A8/Angiotensinogen in direct ELISAs and Western blots. Shows no cross-reactivity with recombinant human Serpin A1, -A3, -A4, -A5, -A6, -C1, -D1, -E2, -F1, -F2, -G1, -I1, -I2, -B6, -B8, -B9, or recombinant mouse Serpin A6.
Source
Monoclonal Mouse IgG1 Clone # 369439
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Serpin A8/Angiotensinogen
Asp34-Ala485
Accession # P01019
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human Serpin A8/Angiotensinogen

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Loading...
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Serpin A8/Angiotensinogen

Angiotensinogen, a member of the serpin family (Serpin A8), is synthesized in liver and cleaved by renin to produce angiotensin I. This is further processed by angiotensin converting enzyme (ACE) to yield angiotensin II, a key blood pressure regulator. The amino acid sequence of human AGT is 99%, 68%, 64%, and 61% identical to that of chimpanzee, canine, rat, and mouse.

Entrez Gene IDs
183 (Human); 11606 (Mouse); 24179 (Rat)
Alternate Names
AGT; alpha-1 antiproteinase, antitrypsin; Angiotensin II; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Angiotensinogen; ANHU; Aogen; FLJ92595; FLJ97926; PAT; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; Serpin A8; SERPINA8angiotensin I

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citations for Human Serpin A8/Angiotensinogen Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
Filter your results:

Filter by:

  1. Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen
    Authors: Jennifer M. Crowther, Letitia H. Gilmour, Benjamin T. Porebski, Sarah G. Heath, Neil R. Pattinson, Maurice C. Owen et al.
    Biochemical Journal
  2. Measurement of the total angiotensinogen and its reduced and oxidised forms in human plasma using targeted LC-MS/MS
    Authors: Lina A. Dahabiyeh, David Tooth, Robin W. Carrell, Randy J. Read, Yahui Yan, Fiona Broughton Pipkin et al.
    Analytical and Bioanalytical Chemistry
  3. A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways
    Authors: Bryan Q. Spring, R. Bryan Bryan Sears, Lei Zak Zheng, Zhiming Mai, Reika Watanabe, Margaret E. Sherwood et al.
    Nature Nanotechnology
  4. Improved Assay for Quantifying a Redox Form of Angiotensinogen as a Biomarker for Pre-Eclampsia: A Case-Control Study.
    Authors: Rahgozar S, Amirian T, Qi M, Shahshahan Z, Entezar-E-Ghaem M, Ghasemi Tehrani H, Miroliaei M, Krilis S, Giannakopoulos B
    PLoS ONE, 2015-08-27;10(8):e0135905.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development (Capture)
  5. Increased urinary Angiotensinogen/Creatinine (AGT/Cr) ratio may be associated with reduced renal function in autosomal dominant polycystic kidney disease patients.
    Authors: Park H, Kang A, Jang J, Kim H, Han M, Oh K, Kim S, Noh J, Cheong H, Hwang Y, Ahn C
    BMC Nephrol, 2015-06-20;16(0):86.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human Serpin A8/Angiotensinogen Antibody

There are currently no reviews for this product. Be the first to review Human Serpin A8/Angiotensinogen Antibody and earn rewards!

Have you used Human Serpin A8/Angiotensinogen Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review