Human PLZF Alexa Fluor® 405-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: PLZF

Human PLZF is a 74 kDa nuclear protein that belongs to the POK family of transcriptional repressors. It is a 673 amino acid protein that contains an N-terminal BTB domain, followed by an acidic domain, a proline-rich region and a C-terminal zinc-finger domain. PLZF forms homodimers with RAR alpha and LAZ3 with its zinc-finger region. Alternate splice forms exist which are tissue-specific and show a deletion of either the BTB domain, the acidic region, or the proline-rich region. Human PLZF shares 96%, 97%, 96%, and 96% amino acid identity with rat, mouse, canine, and bovine PLZF, respectively.

Product Datasheets

Product Specific Notices

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Related Research Areas

• Acute Myeloid Leukemia
• gamma delta T Cells
• Hematopoietic Stem Cell Markers
• Mesenchymal Stem Cell Transcription Factors
• Natural Killer T (NKT) Cells
• Transcription Factors and Regulators
• Transcription Factors in the Akt Pathway