Human Osteopontin (OPN) Quantikine ELISA Kit Summary
Sample Values
Although serum has been validated for use in this assay, it is not a recommended sample type because of proteolytic cleavage by thrombin during the clotting process. Serum values are approximately 50% of the plasma values. See references 32-34 for more details.Sample Type | Mean (ng/mL) | Range (ng/mL) | Standard Deviation (ng/mL) |
EDTA plasma (n=40) | 94.8 | 49.2-175 | 24.9 |
Heparin plasma (n=40) | 96.2 | 53.4-195 | 26.7 |
Urine (n=21) | 2044 | 122-8796 | 1951 |
Cell Culture Supernates:
Condition | Day 1 (ng/mL) | Day 6 (ng/mL) |
Unstimulated | 0.675 | 1.85 |
Stimulated | 1.50 | 2.67 |
HepG2 human hepatocellular carcinoma cells were cultured in MEM supplemented with 5% fetal bovine serum until confluent. Cells were then stimulated with 50 ng/mL PMA for 24 hours. An aliquot of the cell culture supernate was removed, assayed for human OPN and measured 790 ng/mL.
Product Summary
Precision
Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Urine, Human Milk
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 40 | 40 | 40 |
Mean (ng/mL) | 2.3 | 4.9 | 9.3 | 2.36 | 4.81 | 9.17 |
Standard Deviation | 0.092 | 0.126 | 0.267 | 0.155 | 0.274 | 0.499 |
CV% | 4 | 2.6 | 2.9 | 6.6 | 5.7 | 5.4 |
Recovery
The recovery of Osteopontin spiked to three different levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=4) | 104 | 86-113 |
EDTA Plasma (n=4) | 102 | 92-114 |
Heparin Plasma (n=4) | 101 | 95-112 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: Osteopontin/OPN
Osteopontin (OPN), also known as bone sialoprotein (BSP), is a secreted SIBLING family protein that can be variably modified by O- and N-glycosylation, sulfation, phosphorylation, and transglutamination. OPN is widely expressed and is prominent in mineralized tissues. It inhibits bone mineralization and kidney stone formation and promotes inflammation, cell ad¬hesion, and migration. Its expression is upregulat¬ed during inflammation, obesity, atherosclerosis, cancer, and tissue damage and contributes to the pathophysiology of these conditions. The central region of OPN contains RGD and non-RGD binding sites for multiple integrins. Adjacent to the RGD motif is the sequence SLAYGLR (SVVYGLR in human) which serves as a cryptic binding site for additional integrins: it is masked in full length OPN but is exposed following OPN cleavage by multiple proteases in tumors and sites of tissue injury.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 100 µL of Assay Diluent to each well.
- Add 50 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.
- Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
- Aspirate and wash 4 times.
- Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Human Osteopontin (OPN) Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
74
Citations: Showing 1 - 10
Filter your results:
Filter by:
-
The CEBPB+ glioblastoma subcluster specifically drives the formation of M2 tumor-associated macrophages to promote malignancy growth
Authors: Yang, Y;Jin, X;Xie, Y;Ning, C;Ai, Y;Wei, H;Xu, X;Ge, X;Yi, T;Huang, Q;Yang, X;Jiang, T;Wang, X;Piao, Y;Jin, X;
Theranostics
Species: Human
Sample Types: Cell Culture Supernates
-
Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid
Authors: Bhutada, S;Tran-Lundmark, K;Kramer, B;Conner, P;Lowry, AM;Blackstone, E;Frenckner, B;Mesas-Burgos, C;Apte, SS;
Scientific reports
Species: Human
Sample Types: Amniotic Fluid
-
Macrophage-associated markers of metaflammation are linked to metabolic dysfunction in pediatric obesity
Authors: Lischka, J;Schanzer, A;de Gier, C;Greber-Platzer, S;Zeyda, M;
Cytokine
Species: Human
Sample Types: Serum
-
Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy
Authors: Zhao, M;Toma, K;Kinde, B;Li, L;Patel, AK;Wu, KY;Lum, MR;Tan, C;Hooper, JE;Kriegstein, AR;La Torre, A;Liao, YJ;Welsbie, DS;Hu, Y;Han, Y;Duan, X;
Cell reports
Species: Human
Sample Types: Aqueous Humor
-
Plasma Osteopontin Reflects Tissue Damage in Acute Pancreatitis
Authors: Wirestam, L;Nyberg, PB;Dzhendov, T;Gasslander, T;Sandström, P;Sjöwall, C;Björnsson, B;
Biomedicines
Species: Human
Sample Types: Plasma
-
Optimizing Vancomycin Therapy in Critically Ill Children: A Population Pharmacokinetics Study to Inform Vancomycin Area under the Curve Estimation Using Novel Biomarkers
Authors: Downes, KJ;Zuppa, AF;Sharova, A;Neely, MN;
Pharmaceutics
Species: Human
Sample Types: Urine
-
Matrix Metalloproteinases Contribute to the Calcification Phenotype in Pseudoxanthoma Elasticum
Authors: Pl�mers, R;Lindenkamp, C;Osterhage, MR;Knabbe, C;Hendig, D;
Biomolecules
Species: Human
Sample Types: Cell Culture Supernates
-
Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease
Authors: Y Qiu, X Shen, O Ravid, D Atrakchi, D Rand, AE Wight, HJ Kim, S Liraz-Zalt, I Cooper, M Schnaider, H Cantor
Proceedings of the National Academy of Sciences of the United States of America, 2023-02-02;120(6):e2218915120.
Species: Human
Sample Types: Tissue Homogenates
-
The Effect of a Comprehensive Life-Style Intervention Program of Diet and Exercise on Four Bone-Derived Proteins, FGF-23, Osteopontin, NGAL and Sclerostin, in Overweight or Obese Children and Adolescents
Authors: SI Karampatso, G Paltoglou, SM Genitsarid, P Kassari, E Charmandar
Nutrients, 2022-09-13;14(18):.
Species: Human
Sample Types: Serum
-
Association of serum levels of osteopontin and osteoprotegerin with adverse outcomes after endovascular revascularisation in peripheral artery disease
Authors: NPE Kadoglou, D Kapetanios, E Korakas, G Valsami, N Tentolouri, N Papanas, V Lambadiari, C Karkos
Cardiovascular Diabetology, 2022-09-01;21(1):171.
Species: Human
Sample Types: Serum
-
A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma
Authors: Y Lu, A Yang, C Quan, Y Pan, H Zhang, Y Li, C Gao, H Lu, X Wang, P Cao, H Chen, S Lu, G Zhou
Nature Communications, 2022-08-06;13(1):4594.
Species: Human
Sample Types: Cell Culture Supernates
-
A comprehensive approach to predicting weight gain and therapy response in psychopharmacologically treated major depressed patients: A cohort study protocol
Authors: MS Simon, BB Barton, C Glocker, R Musil
PLoS ONE, 2022-07-21;17(7):e0271793.
Species: Human
Sample Types: Plasma
-
Immunometabolic analysis shows a distinct cyto-metabotype in Covid-19 compared to sepsis from other causes
Authors: FM Trovato, S Mujib, E Jerome, A Cavazza, P Morgan, J Smith, MT Depante, K O'Reilly, J Luxton, T Mare, S Napoli, MJ McPhail
Heliyon, 2022-06-24;8(6):e09733.
Species: Human
Sample Types: Plasma
-
The ASIC3-M-CSF-M2 macrophage-positive feedback loop modulates fibroblast-to-myofibroblast differentiation in skin fibrosis pathogenesis
Authors: JJ Wu, ZL Sun, SY Liu, ZH Chen, ZD Yuan, ML Zou, YY Teng, YY Li, DY Guo, FL Yuan
Cell Death & Disease, 2022-06-06;13(6):527.
Species: Human
Sample Types: Cell Culture Supernates
-
Genetics of osteopontin in patients with chronic kidney disease: The German chronic kidney disease study
Authors: Y Cheng, Y Li, N Scherer, F Grundner-C, T Lehtimäki, BH Mishra, OT Raitakari, M Nauck, KU Eckardt, P Sekula, UT Schultheis, GCKD inves
PloS Genetics, 2022-04-06;18(4):e1010139.
Species: Human
Sample Types: Serum
-
Osteopontin-A Potential Biomarker for IgA Nephropathy: Machine Learning Application
Authors: B Moszczuk, N Krata, W Rudnicki, B Foroncewic, D Cysewski, L P?czek, B Kaleta, K Mucha
Biomedicines, 2022-03-22;10(4):.
Species: Human
Sample Types: Urine
-
Protective Effect of Human-Neural-Crest-Derived Nasal Turbinate Stem Cells against Amyloid-beta Neurotoxicity through Inhibition of Osteopontin in a Human Cerebral Organoid Model of Alzheimer's Disease
Authors: JY Lim, JE Lee, SA Park, SI Park, JM Yon, JA Park, SS Jeun, SJ Kim, HJ Lee, SW Kim, SH Yang
Cells, 2022-03-18;11(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
The value of plasma hypoxia markers for predicting imaging-based hypoxia in patients with head-and-neck cancers undergoing definitive chemoradiation
Authors: A Rühle, AL Grosu, N Wiedenmann, J Ruf, B Bieber, R Stoian, AR Thomsen, E Gkika, P Vaupel, D Baltas, WA Weber, M Mix, NH Nicolay
Clinical and translational radiation oncology, 2022-02-21;33(0):120-127.
Species: Human
Sample Types: Plasma
-
Osteopontin and malaria: no direct effect on parasite growth, but correlation with P. falciparum-specific B cells and BAFF in a malaria endemic area
Authors: SE Mortazavi, A Lugaajju, M Kaddumukas, MK Tijani, F Kironde, KEM Persson
BMC microbiology, 2021-11-06;21(1):307.
Species: Human
Sample Types: Plasma
-
Interleukin-33 as an early predictor of cetuximab treatment efficacy in patients with colorectal cancer
Authors: X Zhang, K Bi, X Tu, Q Zhang, Q Cao, Y Liang, P Zeng, L Wang, T Liu, W Fang, H Diao
Cancer Medicine, 2021-10-19;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Osteopontin Levels in Human Milk Are Related to Maternal Nutrition and Infant Health and Growth
Authors: A Aksan, I Erdal, SS Yalcin, J Stein, G Samur
Nutrients, 2021-07-31;13(8):.
Species: Human
Sample Types: Breast Milk
-
Evaluation of a Three-Marker Panel for the Detection of Uveal Melanoma Metastases: A Single-Center Retrospective Analysis
Authors: Z Lin, D Süsskind
Cancers, 2021-05-18;13(10):.
Species: Human
Sample Types: Plasma
-
Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma
Authors: T Seki, N Yanaihara, JS Shapiro, M Saito, J Tabata, R Yokomizo, D Noguchi, T Kuroda, A Kawabata, J Suzuki, K Takahashi, H Matsuzawa, M Miyake, M Takenaka, Y Iida, S Yanagida, A Okamoto
Scientific Reports, 2021-04-08;11(1):7689.
Species: Human
Sample Types: Cell Culture Supernates
-
Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NF&kappaB signaling
Authors: X Jiang, F Zhang, X Ji, F Dong, H Yu, M Xue, Y Qiu, F Yang, X Hu, Z Bao
Cytokine, 2021-02-27;142(0):155474.
Species: Human, Mouse
Sample Types: Cell Culture Supernates, Serum
-
Plasma osteopontin as a biomarker of Alzheimer's disease and vascular cognitive impairment
Authors: YL Chai, JR Chong, AR Raquib, X Xu, S Hilal, N Venketasub, BY Tan, AP Kumar, G Sethi, CP Chen, MKP Lai
Scientific Reports, 2021-02-17;11(1):4010.
Species: Human
Sample Types: Plasma
-
The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma
Authors: K Tokuda, Y Morine, K Miyazaki, S Yamada, Y Saito, M Nishi, T Tokunaga, T Ikemoto, S Imura, M Shimada
Oncotarget, 2021-02-16;12(4):333-343.
Species: Human
Sample Types: Cell Culture Supernates
-
Liver stiffness measured by two-dimensional shear-wave elastography predicts hepatic vein pressure gradient at high values in liver transplant candidates with advanced liver cirrhosis
Authors: S Frankova, M Lunova, H Gottfriedo, R Senkerikov, M Neroldova, J Kovac, E Kieslichov, V Lanska, P Urbanek, J Spicak, M Jirsa, J Sperl
PLoS ONE, 2021-01-07;16(1):e0244934.
Species: Human
Sample Types: Plasma
-
ASP5094, a humanized monoclonal antibody against integrin alpha-9, did not show efficacy in patients with rheumatoid arthritis refractory to methotrexate: results from a phase 2a, randomized, double-blind, placebo-controlled trial
Authors: T Takeuchi, Y Tanaka, J Erdman, Y Kaneko, M Saito, C Higashitan, R Smulders, C Lademacher
Arthritis Res Ther, 2020-10-21;22(1):252.
Species: Human
Sample Types: Plasma
-
Prognostic significance of serum osteopontin levels in small cell lung cancer
Authors: C Xu, Q Yuan, W Wang, C Chi, Q Zhang, L Li, R Yang, Y Wang
BMC Pulm Med, 2020-09-01;20(1):235.
Species: Human
Sample Types: Serum
-
Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease
Authors: B Gómez-Sant, D Saenz de U, M Nuñez-Garc, F Gonzalez-R, X Buque, I Aurrekoetx, V Gutiérrez, MJ Gonzalez-R, C García-Mon, Á González-R, L Mosteiro, G Errazti, P Mifsut, S Gaztambide, L Castaño, C Martin, R Nogueiras, ML Martinez-C, WK Syn, P Aspichueta
Aging Cell, 2020-07-07;0(0):e13183.
Species: Human
Sample Types: Cell Culture Supernates
-
Increased plasma osteopontin levels are associated with nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus
Authors: C Wang, M He, J Peng, S Li, M Long, W Chen, D Liu, G Yang, L Zhang
Cytokine, 2019-09-09;125(0):154837.
Species: Human
Sample Types: Plasma
-
Blood serum proteins as biomarkers for prediction of survival, locoregional control and distant metastasis rate in radiotherapy and radio-chemotherapy for non-small cell lung cancer
Authors: R Suwinski, M Giglok, K Galwas-Kli, A Idasiak, B Jochymek, R Deja, B Maslyk, J Mrochem-Kw, D Butkiewicz
BMC Cancer, 2019-05-08;19(1):427.
Species: Human
Sample Types: Plasma
-
Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization
Authors: SH Choi, AR Kim, JK Nam, JM Kim, JY Kim, HR Seo, HJ Lee, J Cho, YJ Lee
Nat Commun, 2018-11-30;9(1):5108.
Species: Human
Sample Types: Cell Culture Supernates
-
Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients
Authors: CK Wu, MM Su, YF Wu, JJ Hwang, LY Lin
J Clin Med, 2018-11-08;7(11):.
Species: Human
Sample Types: Plasma
-
An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion
Authors: JD Klement, AV Paschall, PS Redd, ML Ibrahim, C Lu, D Yang, E Celis, SI Abrams, K Ozato, K Liu
J. Clin. Invest., 2018-11-05;0(0):.
Species: Human
Sample Types: Serum
-
Assessment of Cross-correlations Between Selected Macromolecules in Urine of Children with Idiopathic Hypercalciuria
Authors: K Jobs, A Jung, S Lewicki, P Murawski, L P?czek, R Zdanowski
Urol J, 2018-09-26;0(0):.
Species: Human
Sample Types: Urine
-
Upregulation of osteopontin expression via the interaction of macrophages and fibroblasts under IL-1b stimulation
Authors: T Shimodaira, K Matsuda, T Uchibori, M Sugano, T Uehara, T Honda
Cytokine, 2018-04-25;110(0):63-69.
Species: Human
Sample Types: Cell Culture Supernates
-
Methylglyoxal-bis-guanylhydrazone inhibits osteopontin expression and differentiation in cultured human monocytes
Authors: X Jin, H Xu, MS McGrath
PLoS ONE, 2018-03-14;13(3):e0192680.
Species: Human
Sample Types: Cell Culture Supernates
-
Association of plasma osteopontin with diabetic retinopathy in Asians with type 2 diabetes
Authors: X Zhang, WK Chee, S Liu, S Tavinthara, CF Sum, SC Lim, N Kumari
Mol. Vis., 2018-02-15;24(0):165-173.
Species: Human
Sample Types: Plasma
-
Effects of oral paricalcitol therapy on arterial stiffness and osteopontin in hypertensive patients with chronic kidney disease and secondary hyperparathyroidism
Authors: M Giakoumis, C Tsioufis, K Dimitriadi, M Sonikian, A Kasiakogia, E Andrikou, T Kalos, D Konstantin, K Filis, D Petras, D Tousoulis
Hellenic J Cardiol, 2018-01-04;0(0):.
Species: Human
Sample Types: Whole Blood
-
Osteopontin is Critical for Hyperactive mTOR-Induced Tumorigenesis in Oral Squamous Cell Carcinoma
Authors: N Gan, S Zou, W Hang, D Yang, X Zhang, Y Yin
J Cancer, 2017-05-12;8(8):1362-1370.
Species: Human
Sample Types: Cell Culture Supernates
-
Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis
PLoS ONE, 2016-12-09;11(12):e0167435.
Species: Human
Sample Types: Cell Culture Supernates
-
Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis
JCI Insight, 2016-12-08;1(20):e90954.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-6 trans-signaling is another pathway to upregulate Osteopontin
Cytokine, 2016-11-15;90(0):88-95.
Species: Human
Sample Types: Cell Culture Supernates
-
Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds
Oncol Lett, 2016-08-24;12(5):3278-3284.
Species: Human
Sample Types: Cell Culture Supernates
-
Immunomodulation Induced by Stem Cell Mobilization and Harvesting in Healthy Donors: Increased Systemic Osteopontin Levels after Treatment with Granulocyte Colony-Stimulating Factor
Int J Mol Sci, 2016-07-19;17(7):.
Species: Human
Sample Types: Plasma
-
Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma
Oncotarget, 2016-05-31;7(22):32156-71.
Species: Human
Sample Types: Cell Culture Supernates
-
Biomarkers of inflammation and axonal degeneration/damage in patients with newly diagnosed multiple sclerosis: contributions of the soluble CD163 CSF/serum ratio to a biomarker panel.
Authors: Stilund M, Gjelstrup M, Petersen T, Moller H, Rasmussen P, Christensen T
PLoS ONE, 2015-04-10;10(4):e0119681.
Species: Human
Sample Types: Serum
-
Prediction of cardiovascular events in statin-treated stable coronary patients of the treating to new targets randomized controlled trial by lipid and non-lipid biomarkers.
Authors: Arsenault B, Barter P, DeMicco D, Bao W, Preston G, LaRosa J, Grundy S, Deedwania P, Greten H, Wenger N, Shepherd J, Waters D, Kastelein J
PLoS ONE, 2014-12-22;9(12):e114519.
Species: Human
Sample Types: Plasma
-
Interleukin 4, interleukin 6 and osteopontin-serological markers of head and neck malignancy in primary diagnostics: A pilot study.
Authors: Aderhold C, Grobschmidt G, Sauter A, Faber A, Hormann K, Schultz J
Oncol Lett, 2014-07-04;8(3):1112-1118.
Species: Human
Sample Types: Serum
-
Prognostic value of secreted phosphoprotein-1 in pleural effusion associated with non-small cell lung cancer.
Authors: Zhang, He, Liu, Hong-bin, Yuan, Dong-mei, Wang, Zhao-fen, Wang, Yun-fen, Song, Yong
BMC Cancer, 2014-04-23;14(0):280.
Species: Human
Sample Types: Pleural Fluid
-
Osteopontin is a prognostic biomarker in non-small cell lung cancer.
Authors: Rud A, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen A, Solberg S, Berge G, Helland A, Brustugun O, Maelandsmo G
BMC Cancer, 2013-11-11;13(0):540.
Species: Human
Sample Types: Serum
-
Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage.
Authors: Yamaguchi Y, Shao Z, Sharif S, Du X, Myles T, Merchant M, Harsh G, Glantz M, Recht L, Morser J, Leung L
J Biol Chem, 2012-11-30;288(5):3097-111.
Species: Human
Sample Types: Tissue Homogenates
-
A multi-analyte assay for the non-invasive detection of bladder cancer.
Authors: Goodison, Steve, Chang, Myron, Dai, Yunfeng, Urquidi, Virginia, Rosser, Charles
PLoS ONE, 2012-10-19;7(10):e47469.
Species: Human
Sample Types: Urine
-
Prognostic utility of pre-operative circulating osteopontin, carbonic anhydrase IX and CRP in renal cell carcinoma.
Br. J. Cancer, 2012-08-23;107(7):1131-7.
Species: Human
Sample Types: Plasma
-
Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients.
Authors: Liersch R, Gerss J, Schliemann C, Bayer M, Schwoppe C, Biermann C, Appelmann I, Kessler T, Lowenberg B, Buchner T, Hiddemann W, Muller-Tidow C, Berdel WE, Mesters R
Blood, 2012-04-17;119(22):5215-20.
Species: Human
Sample Types: Plasma
-
An in vivo platform for tumor biomarker assessment.
Authors: Servais EL, Suzuki K, Colovos C
PLoS ONE, 2011-10-26;6(10):e26722.
Species: Human
Sample Types: Plasma
-
Serum levels of beta-catenin as a potential marker for genotype 4/hepatitis C-associated hepatocellular carcinoma.
Authors: Zekri A, Bahnassy A, Alam El-Din H, Morsy H, Shaarawy S, Moharram N, Daoud S
Oncol Rep, 2011-06-21;26(4):825-31.
Species: Human
Sample Types: Serum
-
Plasma markers for identifying patients with metastatic melanoma.
Authors: Kluger HM, Hoyt K, Bacchiocchi A, Mayer T, Kirsch J, Kluger Y, Sznol M, Ariyan S, Molinaro A, Halaban R
Clin. Cancer Res., 2011-04-12;17(8):2417-25.
Species: Human
Sample Types: Plasma
-
A multi-analyte serum test for the detection of non-small cell lung cancer.
Authors: Farlow EC, Vercillo MS, Coon JS, Basu S, Kim AW, Faber LP, Warren WH, Bonomi P, Liptay MJ, Borgia JA
Br. J. Cancer, 2010-09-21;103(8):1221-8.
Species: Human
Sample Types: Serum
-
Changes in osteopontin and in biomarkers of bone turnover during human endotoxemia.
Authors: Grimm G, Vila G, Bieglmayer C
Bone, 2010-04-24;47(2):388-91.
Species: Human
Sample Types: Plasma
-
Osteopontin as a novel prognostic marker in stable ischaemic heart disease: a 3-year follow-up study.
Authors: Georgiadou P, Iliodromitis EK, Kolokathis F, Varounis C, Gizas V, Mavroidis M, Capetanaki Y, Boudoulas H, Kremastinos DT
Eur. J. Clin. Invest., 2010-04-01;0(0):.
Species: Human
Sample Types: Plasma
-
Circulating levels of osteopontin are closely related to glomerular filtration rate and cardiovascular risk markers in patients with chronic kidney disease.
Authors: Lorenzen J, Kramer R, Kliem V, Bode-Boeger SM, Veldink H, Haller H, Fliser D, Kielstein JT
Eur. J. Clin. Invest., 2010-04-01;40(4):294-300.
Species: Human
Sample Types: Plasma
-
Osteopontin is expressed and functional in human eosinophils.
Authors: Puxeddu I, Berkman N, Ribatti D
Allergy, 2009-10-05;65(2):168-74.
Species: Human
Sample Types: BALF
-
Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.
Authors: Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J
Blood, 2009-07-08;114(15):3181-90.
Species: Human
Sample Types: Cell Culture Supernates
-
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Authors: Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S, Libra M
Clin. Cancer Res., 2008-11-15;14(22):7470-80.
Species: Human
Sample Types: Plasma
-
Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event.
Authors: Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini SE
Proc. Natl. Acad. Sci. U.S.A., 2008-08-08;105(33):11839-44.
Species: Human
Sample Types: Plasma
-
Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells.
Authors: Zdzisinska B, Bojarska-Junak A, Dmoszynska A, Kandefer-Szerszen M
Arch. Immunol. Ther. Exp. (Warsz.), 2008-05-30;56(3):207-21.
Species: Human
Sample Types: Cell Culture Supernates
-
Intensive lipid-lowering therapy ameliorates novel calcification markers and GSM score in patients with carotid stenosis.
Authors: Kadoglou NP, Gerasimidis T, Moumtzouoglou A, Kapelouzou A, Sailer N, Fotiadis G, Vitta I, Katinios A, Kougias P, Bandios S, Voliotis K, Karayannacos PE, Liapis CD
Eur J Vasc Endovasc Surg, 2008-04-18;35(6):661-8.
Species: Human
Sample Types: Plasma
-
Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide.
Authors: Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL
J. Immunol., 2008-03-01;180(5):3520-34.
Species: Human
Sample Types: Cell Culture Supernates
-
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
Authors: Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, Mancini C, Lazzaretti M, Mazzera L, Ravanetti L, Bonomini S, Ferrari L, Miranda C, Ladetto M, Neri TM, Neri A, Greco A, Mangoni M, Bonati A, Rizzoli V, Giuliani N
Blood, 2007-09-11;110(13):4464-75.
Species: Human
Sample Types: Cell Culture Supernates
-
Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse: roles of osteopontin.
Authors: Shao J, Washington MK, Saxena R, Sheng H
Carcinogenesis, 2007-08-11;28(12):2476-83.
Species: Human
Sample Types: Cell Culture Supernates
-
An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma.
Authors: Meinhold-Heerlein I, Bauerschlag D, Zhou Y, Sapinoso LM, Ching K, Frierson H, Brautigam K, Sehouli J, Stickeler E, Konsgen D, Hilpert F, von Kaisenberg CS, Pfisterer J, Bauknecht T, Jonat W, Arnold N, Hampton GM
Clin. Cancer Res., 2007-01-15;13(2):458-66.
Species: Human
Sample Types: Serum
-
Osteopontin expression and serum levels in metastatic uveal melanoma: a pilot study.
Authors: Pe'er J
Invest. Ophthalmol. Vis. Sci., 2006-03-01;47(3):802-6.
Species: Human
Sample Types: Serum
FAQs
No product specific FAQs exist for this product, however you may
View all ELISA FAQsReviews for Human Osteopontin (OPN) Quantikine ELISA Kit
Average Rating: 5 (Based on 4 Reviews)
Have you used Human Osteopontin (OPN) Quantikine ELISA Kit?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
Measured plasma at 25-fold dilution and urine at 200-fold dilution. We were able to obtain values in range for both biofluids.