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Human Neuronal Pentraxin R (NP_055108.2) VersaClone cDNA

Catalog #: RDC3516 Datasheet / COA / SDS
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RDC3516
Human Neuronal Pentraxin R (NP_055108.2) VersaClone cDNA
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Human Neuronal Pentraxin R (NP_055108.2) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: Neuronal Pentraxin R/NPTXR

NPTXR (Neuronal Pentraxin Receptor; also NPR) is a 65 kDa, type II transmembrane glycoprotein that binds Neuronal Pentraxins 1 and 2. It is expressed on cerebellar Purkinje and granule cells, and hippocampal neurons of the CA1, CA3 and dentate gyrus regions. Human Neuronal Pentraxin Receptor is 499 amino acids (aa) in length. It contains a two aa cytoplasmic tail, a 21 aa transmembrane segment, and a 476 aa extracellular region with one Pentraxin domain (aa 295 - 499). One alternate start site exists at Met12, and a 55 kDa soluble form of NPTXR (possibly beginning at Gln56) may be generated by proteolytic cleavage. Over aa 24 - 499, human NPTXR is 87% aa identical to mouse NPTXR.

Entrez Gene IDs
23467 (Human); 73340 (Mouse); 81005 (Rat)
Alternate Names
Neuronal Pentraxin R; neuronal pentraxin receptor; NPR; NPTXR

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