Home / CD117/c-kit / Human/Mouse CD117/c-kit Antibody

Human/Mouse CD117/c-kit Antibody

Catalog #: AF1356
116 Citations 8 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF1356
AF1356-SP
CD117/c-kit in Mouse Embryo.
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Product Details
Citations (116)
FAQs
Supplemental Products
Reviews (8)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse CD117/c-kit Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse CD117/c-kit in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CD117/c-kit
Gln25-Thr519 (Ala207Glu)
Accession # P05532
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
See below
Simple Western
5 µg/mL
See below
Flow Cytometry
2.5 µg/106 cells
Lineage depleted mouse bone marrow cells
Immunohistochemistry
5-15 µg/mL
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Dual RNAscope ISH-IHC
5-15 µg/mL
Immersion fixed paraffin-embedded sections of human mouse embryos

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry CD117/c-kit antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

CD117/c-kit in Mouse Embryo. CD117/c-kit was detected in immersion fixed frozen sections of mouse embryo using Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Western Blot Detection of Human and Mouse CD117/c-kit antibody by Western Blot. View Larger

Detection of Human and Mouse CD117/c-kit by Western Blot. Western blot shows lysates of MO7e human megakaryocytic leukemic cell line, P815 mouse mastocytoma cell line, and MC/9-2 mouse mast cell line. PVDF membrane was probed with 0.1 µg/mL of Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). Specific bands were detected for CD117/c-kit at approximately 135, 150 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Simple Western Detection of Human and Mouse CD117/c-kit antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Human and Mouse CD117/c-kit by Simple WesternTM. Simple Western lane view shows lysates of MO7e human megakaryocytic leukemic cell line, P815 mouse mastocytoma cell line and MC/9-2 mouse mast cell line, loaded at 0.2 mg/mL. A specific band was detected for CD117/c-kit at approximately 150-165 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD117/c-kit by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD117/c-kit by Immunocytochemistry/Immunofluorescence Localization of MAFB in mouse testes.(A) Localization of MAFB in E18.5 mouse testes. Double immunostaining of MAFB with E-cadherin (ECAD), GATA4, or STAR is shown. Nuclei were counterstained with DAPI. The color of each marker is indicated above the images. G; germ cells. S; Sertoli cells. L; Leydig cells. MAFB was specifically detected in Leydig cells and Sertoli cells. (B) Localization of MAFB in adult mouse testes. Double immunostaining of MAFB with E-cadherin (ECAD), KIT, SCP3, PNA Lectin, or vimentin is shown. Nuclei were counterstained with DAPI. The color of each marker is indicated above the images. All seminiferous tubules shown represent stage VII. US; undifferentiated spermatogonia. DS; differentiated spermatogonia. P; pachytene spermatocytes. Sp; spermatids. S; Sertoli cells. L; Leydig cells. MAFB was specifically detected in Leydig cells, Sertoli cells, and pachytene spermatocytes. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0190800), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD117/c-kit by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD117/c-kit by Immunocytochemistry/Immunofluorescence Spermatogenesis development of adult Mafb-cKO mice.Six-week-old mice were injected with tamoxifen and testes of cKO mice at 3- and 8-months of age were examined compared to those of age-matched controls (n = 4 for each group). (A) Testicular sections stained with Periodic acid-Schiff (PAS). (B) Immunostaining with various testicular cell types; undifferentiated spermatogonia (GFRA1 and PLZF), differentiated spermatogonia (KIT+ inside the tubule), spermatocytes (SCP3), spermatids (PNA-Lectin), Sertoli cells (SOX9 and Vimentin), and Leydig cells (KIT+ outside the tubule and STAR). The color of markers is indicated in the left boxes in panels. Colored arrows corresponding to the boxed markers are shown. (C) The expression level of the genes involved in testis function and germ cell development. The marker genes representing undifferentiated spermatogonia (Nanos3), differentiated spermatogonia (c-Kit), undifferentiated and differentiated spermatogonia (Sohlh1), differentiated spermatogonia and preleptotene spermatocytes (Stra8), spermatids (Prm2), Leydig cells (Hsd3b1), and Sertoli cells (Sox9) were analyzed by qRT-PCR. Each reaction was performed in duplicate for each gene. The data represent the means±SEM and are shown as relative mRNA expression after normalization to Hprt. *P<0.05. (D) The proportion of seminiferous stages: I-III, IV-VI, VII-VIII, and IX-XII from each genotype. *P<0.05. M; Month. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0190800), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD117/c-kit by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD117/c-kit by Immunocytochemistry/Immunofluorescence ANXA8+ve/c-kit+ve luminal progenitor cells are mostly Ki67−ve.Co-immunofluorescence staining for ANXA8 (green), c-kit (red), and Ki67 (purple) in mouse mammary gland from virgin and mid-pregnant mice shows that ANXA8+ve cells express c-kit, but not Ki67. The Ki67 staining has been coloured purple for easier visualisation in the triple-merged image. These are representative images of at least three independent mice for each time point. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25803307), licensed under a CC-BY license. Not internally tested by R&D Systems.

In-situ Hybridization View Larger

Detection of CD117/c-kit in Human Mouse Embryos. Formalin-fixed paraffin-embedded tissue sections of mouse embryo were probed for CD117 mRNA (ACD RNAScope Probe, catalog # 314158; Fast Red chromogen, ACD catalog # 322750). Adjacent tissue section was processed for immunohistochemistry using goat anti-mouse CD117 polyclonal antibody (R&D Systems catalog # AF1356) at 5ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to cell membrane in esophagus in mouse embryo.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD117/c-kit

Stem cell factor receptor (CD117, the gene product of the c-kit protooncogene) and its ligand, stem cell factor (also named c-kit ligand, mast cell growth factor), play essential roles in gametogenesis, melanogenesis and hematopoiesis. It is a transmembrane tyrosine kinase that is expressed on endothelial cells, mast cells, megakaryocytes, stem cells and multiple embryonic cells, such as melanoblasts and primordial germ cells. 

Long Name
Stem Cell Factor Receptor
Entrez Gene IDs
3815 (Human); 16590 (Mouse); 64030 (Rat)
Alternate Names
CD117 antigen; CD117; ckit; c-kit; EC 2.7.10; EC 2.7.10.1; KIT; PBT; piebald trait; Proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; SCF R; SCFR; SCFRmast/stem cell growth factor receptor; soluble KIT variant 1; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

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Citations for Human/Mouse CD117/c-kit Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

116 Citations: Showing 1 - 10
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  1. Streptozotocin?induced diabetic mice exhibit reduced experimental choroidal neovascularization but not corneal neovascularization
    Authors: G Liu, L Chen, Q Cai, H Wu, Z Chen, X Zhang, P Lu
    Mol Med Rep, 2018-09-03;0(0):.
  2. Yeokwisan, a Standardized Herbal Formula, Enhances Gastric Emptying via Modulation of the Ghrelin Pathway in a Loperamide-induced Functional Dyspepsia Mouse Model
    Authors: Seung-Ju Hwang, Jing-Hua Wang, Jin-Seok Lee, Hwa-Dong Lee, Tae-Joon Choi, Seo-Hyung Choi et al.
    Frontiers in Pharmacology
  3. The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice
    Authors: Peart NJ, Johnson TA, Lee S et al.
    PLOS Genetics
  4. WNK1 is required during male pachynema to sustain fertility
    Authors: Ru-pin Alicia Chi, Xiaojiang Xu, Jian-Liang Li, Xin Xu, Guang Hu, Paula Brown et al.
    iScience
  5. Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms
    Authors: Elodie Grockowiak, Claudia Korn, Justyna Rak, Veronika Lysenko, Adrien Hallou, Francesca M. Panvini et al.
    Nature Cancer
  6. Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells
    Authors: Rahul Mallick, Erika Gurzeler, Pyry I. Toivanen, Tiina Nieminen, Seppo Ylä-Herttuala
    Frontiers in Bioengineering and Biotechnology
  7. Critical role of SDF-1 alpha -induced progenitor cell recruitment and macrophage VEGF production in the experimental corneal neovascularization
    Authors: Gaoqin Liu, Peirong Lu, Longbiao Li, Hui Jin, Xuefei He, Naofumi Mukaida et al.
    Mol Vis
  8. Lipid phosphatase SHIP-1 regulates chondrocyte hypertrophy and skeletal development
    Authors: So EY, Sun C, Wu KQ et al.
    J. Cell. Physiol.
  9. NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells
    Authors: Azzurra Codino, Tomasz Turowski, Louie N. van de Lagemaat, Ivayla Ivanova, Andrea Tavosanis, Christian Much et al.
    iScience
  10. Identification of dynamic undifferentiated cell states within the male germline
    Authors: HM La, JA Mäkelä, AL Chan, FJ Rossello, CM Nefzger, JMD Legrand, M De Seram, JM Polo, RM Hobbs
    Nat Commun, 2018-07-19;9(1):2819.
  11. Transduction of Systemically Administered Adeno-Associated Virus in the Colonic Enteric Nervous System and c-Kit Cells of Adult Mice
    Authors: Lixin Wang, Pu-Qing Yuan, Collin Challis, Sripriya Ravindra Kumar, Yvette Taché
    Frontiers in Neuroanatomy
  12. RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis
    Authors: Liu C, Wang L, Li Y et al.
    Nucleic acids research
  13. A Novel Population of Myeloid Cells Responding to Coxsackievirus Infection Assists in the Dissemination of Virus within the Neonatal CNS
    Authors: Jenna M. Tabor-Godwin, Chelsea M. Ruller, Nolan Bagalso, Naili An, Robb R. Pagarigan, Stephanie Harkins et al.
    Journal of Neuroscience
  14. The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis
    Authors: Rivero-Hinojosa S, Pugacheva EM, Kang S et al.
    Nature Communications
  15. Differential RA responsiveness among subsets of mouse late progenitor spermatogonia
    Authors: Shinnosuke Suzuki, John R. McCarrey, Brian P. Hermann
    Reproduction
  16. The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes
    Authors: Sarah C. Moody, Penny A. F. Whiley, Patrick S. Western, Kate L. Loveland
    Front Endocrinol (Lausanne)
  17. Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis
    Authors: Hirano K, Nonami Y, Nakamura Y et al.
    Communications Biology
  18. Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health
    Authors: Jessica M. Stringer, Amy Winship, Nadeen Zerafa, Matthew Wakefield, Karla Hutt
    Proceedings of the National Academy of Sciences
  19. KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice
    Authors: Dexter A. Myrick, Michael A. Christopher, Alyssa M. Scott, Ashley K. Simon, Paul G. Donlin-Asp, William G. Kelly et al.
    PLOS ONE
  20. Dystrophin Deficiency Causes Progressive Depletion of Cardiovascular Progenitor Cells in the Heart
    Authors: Jelinkova S, Sleiman Y, FojtIk P et al.
    International Journal of Molecular Sciences
  21. WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility
    Authors: Okiko Habara, Catriona Y. Logan, Masami Kanai-Azuma, Roeland Nusse, Hinako M. Takase
    Development
  22. Defective germline reprogramming rewires the spermatogonial transcriptome
    Authors: Lina Vasiliauskaitė, Rebecca V. Berrens, Ivayla Ivanova, Claudia Carrieri, Wolf Reik, Anton J. Enright et al.
    Nature Structural & Molecular Biology
  23. Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine
    Authors: Hiromichi Shimizu, Ryuichi Okamoto, Go Ito, Satoru Fujii, Toru Nakata, Kohei Suzuki et al.
    PeerJ
  24. Efficient Surface Immobilization of Chemically Modified Hyaluronans for Enhanced Bioactivity and Survival of In Vitro-Cultured Embryonic Salivary Gland Mesenchymal Cells
    Authors: Sang-woo Lee, Junchul Kim, Xin Cong, Guang-Yan Yu, Ji Hyun Ryu, Kyungpyo Park
    Polymers (Basel)
  25. A direct role for murine Cdx proteins in the trunk neural crest-gene regulatory network
    Authors: Oraly Sanchez-Ferras, Guillaume Bernas, Omar Farnos, Aboubacrine M. Touré, Ouliana Souchkova, Nicolas Pilon
    Development
  26. Mast Cells Are the Trigger of Small Vessel Disease and Diastolic Dysfunction in Diabetic Obese Mice
    Authors: Sarah Guimbal, Lauriane Cornuault, Paul Rouault, Pierre-Louis Hollier, Candice Chapouly, Marie-Lise Bats et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  27. Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long‐term hematopoiesis
    Authors: Takahiko Imai, Hiroki Tanaka, Yoko Hamazaki, Nagahiro Minato
    Cancer Science
  28. Stimulation of C-Kit+ Retinal Progenitor Cells by Stem Cell Factor Confers Protection Against Retinal Degeneration
    Authors: Xi Chen, Shanshan Li, Xiaoli Liu, Jingjie Zhao, Lanting Wu, Ran You et al.
    Frontiers in Pharmacology
  29. Identification of primordial germ cell-like cells as liver metastasis initiating cells in mouse tumour models
    Authors: Liu C, Ma Z, Cai Z et Al.
    Cell Discov
  30. GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance
    Authors: Hue M. La, Ai-Leen Chan, Julien M. D. Legrand, Fernando J. Rossello, Christina G. Gangemi, Antonella Papa et al.
    Development
  31. Sertoli cells are the unique source of stem cell factor for spermatogenesis
    Authors: Yi Jacky Peng, Xinyu Thomas Tang, Hui Sophie Shu, Wenjie Dong, Hongfang Shao, Bo O. Zhou
    Development
  32. Vagal Intramuscular Arrays: The Specialized Mechanoreceptor Arbors That Innervate the Smooth Muscle Layers of the Stomach Examined in the Rat
    Authors: Terry L. Powley, Cherie N. Hudson, Jennifer L. McAdams, Elizabeth A. Baronowsky, Robert J. Phillips
    Journal of Comparative Neurology
  33. Cellular and subcellular localization of cholecystokinin (CCK)-1 receptors in the pancreas, gallbladder, and stomach of mice
    Authors: Kohtarou Konno, Hiromi Takahashi-Iwanaga, Motokazu Uchigashima, Kyoko Miyasaka, Akihiro Funakoshi, Masahiko Watanabe et al.
    Histochemistry and Cell Biology
  34. CENP-A is essential for cardiac progenitor cell proliferation
    Authors: Michael McGregor, Nirmala Hariharan, Anya Y Joyo, Robert L Margolis, Mark A Sussman
    Cell Cycle
  35. Neural Crest–Derived Stem Cells Migrate and Differentiate Into Cardiomyocytes After Myocardial Infarction
    Authors: Yuichi Tamura, Keisuke Matsumura, Motoaki Sano, Hidenori Tabata, Kensuke Kimura, Masaki Ieda et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  36. Adeno-associated virus-9 reverses delayed gastric emptying of solids in diabetic mice.
    Authors: Li X, Ji S et al.
    Neurogastroenterol Motil
    Species: Mouse
    Sample Types:
    Applications: Simple Western
  37. Conditional loss of Brca1 in oocytes causes reduced litter size, ovarian reserve depletion and impaired oocyte in vitro maturation with advanced reproductive age in mice
    Authors: Winship, AL;Alesi, LR;Stringer, JM;Cao, Y;Lewis, YM;Tu, L;Swindells, EOK;Giridharan, S;Cai, X;Griffiths, MJ;Zerafa, N;Gilham, L;Hickey, M;Hutt, KJ;
    EBioMedicine
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  38. Inhibition of EZH2 Reduces Aging-Related Decline in Interstitial Cells of Cajal of the Mouse Stomach
    Authors: Taheri, N;Choi, EL;Thuy Nguyen, VT;Zhang, Y;Huynh, NM;Kellogg, TA;van Wijnen, AJ;Ordog, T;Hayashi, Y;
    Cellular and molecular gastroenterology and hepatology
    Species: Transgenic Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  39. Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis
    Authors: Iga, T;Kobayashi, H;Kusumoto, D;Sanosaka, T;Fujita, N;Tai-Nagara, I;Ando, T;Takahashi, T;Matsuo, K;Hozumi, K;Ito, K;Ema, M;Miyamoto, T;Matsumoto, M;Nakamura, M;Okano, H;Shibata, S;Kohyama, J;Kim, KK;Takubo, K;Kubota, Y;
    Nature cell biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  40. SRSF1-mediated alternative splicing is required for spermatogenesis
    Authors: Lei, WL;Li, YY;Du, Z;Su, R;Meng, TG;Ning, Y;Hou, G;Schatten, H;Wang, ZB;Han, Z;Sun, F;Qian, WP;Liu, C;Sun, QY;
    International journal of biological sciences
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  41. An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    Authors: Hansen, SL;Larsen, HL;Pikkupeura, LM;Maciag, G;Guiu, J;Müller, I;Clement, DL;Mueller, C;Johansen, JV;Helin, K;Lerdrup, M;Jensen, KB;
    Science advances
    Species: Mouse
    Sample Types: Organoids
    Applications: IHC
  42. Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
    Authors: Zhang, X;Liu, Y;Sosa, F;Gunewardena, S;Crawford, PA;Zielen, AC;Orwig, KE;Wang, N;
    Cell reports
    Species: Mouse
    Sample Types: Protein, Whole Cells, Whole Tissue
    Applications: ICC/IF, IHC, Western Blot
  43. RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis
    Authors: Liu C, Wang L, Li Y et al.
    Nucleic acids research
  44. Insulin-like growth factor1 preserves gastric pacemaker cells and motor function in aging via ERK1/2 activation
    Authors: Nguyen, VTT;Taheri, N;Choi, EL;Kellogg, TA;Linden, DR;Hayashi, Y;
    Cellular and molecular gastroenterology and hepatology
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  45. Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
    Authors: Nakajima-Takagi, Y;Oshima, M;Takano, J;Koide, S;Itokawa, N;Uemura, S;Yamashita, M;Andoh, S;Aoyama, K;Isshiki, Y;Shinoda, D;Saraya, A;Arai, F;Yamaguchi, K;Furukawa, Y;Koseki, H;Ikawa, T;Iwama, A;
    eLife
    Species: Transgenic Mouse, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  46. Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
    Authors: Hao, X;Shen, Y;Chen, N;Zhang, W;Valverde, E;Wu, L;Chan, HL;Xu, Z;Yu, L;Gao, Y;Bado, I;Michie, LN;Rivas, CH;Dominguez, LB;Aguirre, S;Pingel, BC;Wu, YH;Liu, F;Ding, Y;Edwards, DG;Liu, J;Alexander, A;Ueno, NT;Hsueh, PR;Tu, CY;Liu, LC;Chen, SH;Hung, MC;Lim, B;Zhang, XH;
    Cell stem cell
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  47. SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse
    Authors: A Uchida, K Imaimatsu, H Suzuki, X Han, H Ushioda, M Uemura, K Imura-Kish, R Hiramatsu, HM Takase, Y Hirate, A Ogura, M Kanai-Azum, A Kudo, Y Kanai
    Nature Communications, 2022-12-21;13(1):7860.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  48. New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance
    Authors: T Klein-Rode, K Micklich, A Sanz-Moren, M Tost, J Calzada-Wa, T Adler, M Klaften, S Sabrautzki, B Aigner, M Kraiger, V Gailus-Dur, H Fuchs, German Mou, A Gründer, H Pahl, E Wolf, M Hrabe de A, B Rathkolb
    Scientific Reports, 2022-11-17;12(1):19793.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  49. Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis
    Authors: Z Zheng, H He, XT Tang, H Zhang, F Gou, H Yang, J Cao, S Shi, Z Yang, G Sun, X Xie, Y Zeng, A Wen, Y Lan, J Zhou, B Liu, BO Zhou, T Cheng, H Cheng
    Cell Stem Cell, 2022-11-03;29(11):1562-1579.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  50. The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice
    Authors: Peart NJ, Johnson TA, Lee S et al.
    PLOS Genetics
  51. Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis
    Authors: Hirano K, Nonami Y, Nakamura Y et al.
    Communications Biology
  52. Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells
    Authors: S Klingler, KS Hsu, G Hua, ML Martin, M Adileh, T Baslan, Z Zhang, PB Paty, Z Fuks, AM Brown, R Kolesnick
    JCI Insight, 2022-03-08;7(5):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  53. Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation
    Authors: J Heil, V Olsavszky, K Busch, K Klapproth, C de la Torr, C Sticht, K Sandorski, J Hoffmann, H Schönhaber, J Zierow, M Winkler, CD Schmid, T Staniczek, DE Daniels, J Frayne, G Metzgeroth, D Nowak, S Schneider, M Neumaier, V Weyer, C Groden, HJ Gröne, K Richter, C Mogler, MM Taketo, K Schledzews, C Géraud, S Goerdt, PS Koch
    Nature Communications, 2021-11-29;12(1):6963.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  54. Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
    Authors: IC Young, B Wu, J Andricovic, ST Chuang, R Li, A Tzatsos, RC Wu, MY Wu
    Cell Reports, 2021-11-23;37(8):110036.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  55. Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis
    Authors: A Heinrich, B Bhandary, SJ Potter, N Ratner, T DeFalco
    Cell Reports, 2021-10-26;37(4):109885.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  56. Regulation of intestinal immunity and tissue repair by enteric glia
    Authors: F Progatzky, M Shapiro, SH Chng, B Garcia-Cas, CH Classon, S Sevgi, A Laddach, AC Bon-Frauch, R Lasrado, M Rahim, EM Amaniti, S Boeing, K Shah, LJ Entwistle, A Suárez-Bon, MS Wilson, B Stockinger, V Pachnis
    Nature, 2021-10-20;599(7883):125-130.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo
    Authors: K Kimura, M Breitbach, FA Schildberg, M Hesse, BK Fleischman
    Bone Reports, 2021-09-29;15(0):101133.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  58. Telocytes in the human ascending aorta: Characterization and exosome-related KLF-4/VEGF-A expression
    Authors: T Aschacher, K Schmidt, O Aschacher, E Eichmair, U Baranyi, B Winkler, M Grabenwoeg, A Spittler, F Enzmann, B Messner, J Riebandt, G Laufer, M Bergmann, M Ehrlich
    Journal of Cellular and Molecular Medicine, 2021-09-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  59. The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis
    Authors: Rivero-Hinojosa S, Pugacheva EM, Kang S et al.
    Nature Communications
  60. Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells
    Authors: W Jia, L Kong, H Kidoya, H Naito, F Muramatsu, Y Hayashi, HY Hsieh, D Yamakawa, DK Hsu, FT Liu, N Takakura
    Nature Communications, 2021-04-09;12(1):2118.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  61. Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis
    Authors: K Matsumoto, M Suenaga, Y Mizutani, K Matsui, A Yoshida, T Nakamoto, S Kato
    Journal of pharmacological sciences, 2021-04-07;146(3):125-135.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  62. An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia
    Authors: S Suzuki, JR McCarrey, BP Hermann
    Cell Reports, 2021-02-16;34(7):108752.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  63. Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules
    Authors: K Imura-Kish, A Uchida, N Tsunekawa, H Suzuki, HM Takase, Y Hirate, M Kanai-Azum, R Hiramatsu, M Kurohmaru, Y Kanai
    Scientific Reports, 2021-01-13;11(1):1110.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. Single-cell transcriptomics reveals zone-specific alterations of liver sinusoidal endothelial cells in cirrhosis
    Authors: T Su, Y Yang, S Lai, J Jeong, Y Jung, M McConnell, T Utsumi, Y Iwakiri
    Cellular and Molecular Gastroenterology and Hepatology, 2020-12-16;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
    Authors: N Apóstolo, SN Smukowski, J Vanderlind, G Condomitti, V Rybakin, J Ten Bos, L Trobiani, S Portegies, KM Vennekens, NV Gounko, D Comoletti, KD Wierda, JN Savas, J de Wit
    Nat Commun, 2020-10-14;11(1):5171.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  66. Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development
    Authors: EI Crosse, S Gordon-Key, S Rybtsov, A Binagui-Ca, H Felchle, NC Nnadi, K Kirschner, T Chandra, S Tamagno, DJ Webb, F Rossi, RA Anderson, A Medvinsky
    Cell Stem Cell, 2020-09-17;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  67. Defective development and microcirculation of intestine in Npr2 mutant mice
    Authors: C Sogawa-Fuj, A Hanagata, Y Fujiwara, Y Ishida, H Tomiyasu, T Kunieda, H Nakatomi, M Hori
    Sci Rep, 2020-09-08;10(1):14761.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  68. PIM1 Promotes Survival of Cardiomyocytes by Upregulating c-Kit Protein Expression
    Authors: DE Ebeid, F Firouzi, CY Esquer, JM Navarrete, BJ Wang, NA Gude, MA Sussman
    Cells, 2020-08-31;9(9):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  69. Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion during Aging
    Authors: Y Hayashi, DT Asuzu, MR Bardsley, GB Gajdos, SM Kvasha, DR Linden, RA Nagy, SA Saravanape, SA Syed, Y Toyomasu, H Yan, EN Chini, SJ Gibbons, TA Kellogg, K Khazaie, M Kuro-O, JM Espindola, MP Singh, JG Tidball, M Wehling-He, G Farrugia, T Ordog
    Cell Mol Gastroenterol Hepatol, 2020-08-07;0(0):.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  70. DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors
    Authors: MM Mikedis, Y Fan, PK Nicholls, T Endo, EK Jackson, SA Cobb, DG de Rooij, DC Page
    Elife, 2020-07-20;9(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  71. Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis
    Authors: A Heinrich, SJ Potter, L Guo, N Ratner, T DeFalco
    Cell Rep, 2020-04-14;31(2):107513.
    Species: Mouse
    Sample Types: Testes
    Applications: IF
  72. Multipotency of mouse trophoblast stem cells
    Authors: M Hou, J Han, G Li, MY Kwon, J Jiang, S Emani, ES Taglauer, JA Park, EB Choi, M Vodnala, YW Fong, SM Emani, IO Rosas, MA Perrella, X Liu
    Stem Cell Res Ther, 2020-02-13;11(1):55.
    Species: Human, Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  73. Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells
    Authors: P Agarwal, S Isringhaus, H Li, AJ Paterson, J He, Á Gomariz, T Nagasawa, C Nombela-Ar, R Bhatia
    Cell Stem Cell, 2019-03-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  74. Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis
    Authors: H Kidoya, F Muramatsu, T Shimamura, W Jia, T Satoh, Y Hayashi, H Naito, Y Kunisaki, F Arai, M Seki, Y Suzuki, T Osawa, S Akira, N Takakura
    Nat Commun, 2019-03-06;10(1):1072.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  75. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
    Authors: JMD Legrand, AL Chan, HM La, FJ Rossello, ML Änkö, FV Fuller-Pac, RM Hobbs
    Nat Commun, 2019;10(1):2278.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  76. Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis
    Authors: S Saeidi, F Shapouri, RU de Iongh, F Casagranda, JM Sutherland, PS Western, EA McLaughlin, M Familari, GR Hime
    PLoS ONE, 2018-01-11;13(1):e0190925.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  77. Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis
    Authors: Y Kawai, A Oda, Y Kanai, R Goitsuka
    PLoS ONE, 2018-01-02;13(1):e0190702.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  78. Cardiac Nestin+ Cells Derived from Early Stage of Dilated Cardiomyopathy Enhanced the Survival of the Doxorubicin-Injured Cardiac Muscle HL-1 Cells
    Authors: D Xie, Y Liao, B Wu, Y Chen, W Lin, D Lu, S Gao, S Zhu, C Peng, MH Jiang
    Int Heart J, 2018-01-01;59(1):180-189.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  79. Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer
    Authors: JC Harrell, TM Shroka, BM Jacobsen
    Oncogenesis, 2017-11-27;6(11):2.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: Western Blot
  80. Multicolor quantitative confocal imaging cytometry
    Authors: DL Coutu, KD Kokkaliari, L Kunz, T Schroeder
    Nat. Methods, 2017-11-13;15(1):39-46.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  81. Live cell screening platform identifies PPAR? as a regulator of cardiomyocyte proliferation and cardiac repair
    Authors: A Magadum, Y Ding, L He, T Kim, MD Vasudevara, Q Long, K Yang, N Wickramasi, HV Renikunta, N Dubois, G Weidinger, Q Yang, FB Engel
    Cell Res., 2017-06-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  82. A transit-amplifying population underpins the efficient regenerative capacity of the testis
    Authors: C Carrieri, S Comazzetto, A Grover, M Morgan, A Buness, C Nerlov, D O'Carroll
    J. Exp. Med., 2017-05-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  83. Concurrent Isolation of Three Distinct Cardiac Stem Cell Populations from a Single Human Heart Biopsy
    Authors: MM Monsanto, KS White, T Kim, BJ Wang, K Fisher, K Ilves, FG Khalafalla, A Casillas, K Broughton, S Mohsin, WP Dembitsky, MA Sussman
    Circ. Res., 2017-04-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  84. Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures
    Authors: MY Lee, SE Ha, C Park, PJ Park, R Fuchs, L Wei, BG Jorgensen, D Redelman, SM Ward, KM Sanders, S Ro
    PLoS ONE, 2017-04-20;12(4):e0176031.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  85. Fabrication of Synthetic Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice
    Authors: L Luo, J Tang, K Nishi, C Yan, PU Dinh, J Cores, T Kudo, J Zhang, TS Li, K Cheng
    Circ. Res, 2017-03-15;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  86. Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes
    Authors: AL Feng, YY Xiang, L Gui, G Kaltsidis, Q Feng, WY Lu
    Diabetologia, 2017-03-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  87. Radiation Exposure Decreases the Quantity and Quality of Cardiac Stem Cells in Mice
    PLoS ONE, 2016-05-19;11(5):e0152179.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  88. Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.
    Authors: Liu Q, Yang R, Huang X, Zhang H, He L, Zhang L, Tian X, Nie Y, Hu S, Yan Y, Zhang L, Qiao Z, Wang Q, Lui K, Zhou B
    Cell Res, 2015-12-04;26(1):119-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  89. Embryonic Hematopoietic Progenitor Cells Reside in Muscle before Bone Marrow Hematopoiesis.
    Authors: Tanaka Y, Inoue-Yokoo T, Kulkeaw K, Yanagi-Mizuochi C, Shirasawa S, Nakanishi Y, Sugiyama D
    PLoS ONE, 2015-09-21;10(9):e0138621.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  90. Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment.
    Authors: Quijada P, Hariharan N, Cubillo J, Bala K, Emathinger J, Wang B, Ormachea L, Bers D, Sussman M, Poizat C
    J Biol Chem, 2015-08-31;290(42):25411-26.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  91. Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.
    Authors: Iglesias J, Cairney C, Ferrier R, McDonald L, Soady K, Kendrick H, Pringle M, Morgan R, Martin F, Smalley M, Blyth K, Stein T
    PLoS ONE, 2015-03-24;10(3):e0119718.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  92. Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth.
    Authors: Shiu J, Piazuelo M, Ding H, Czinn S, Drakes M, Banerjee A, Basappa N, Kobayashi K, Fricke W, Blanchard T
    Mucosal Immunol, 2015-01-21;8(5):1047-59.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  93. Isolation and characterization of resident endogenous c-Kit+ cardiac stem cells from the adult mouse and rat heart.
    Authors: Smith A, Lewis F, Aquila I, Waring C, Nocera A, Agosti V, Nadal-Ginard B, Torella D, Ellison G
    Nat Protoc, 2014-06-19;9(7):1662-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  94. c-kit+ cells minimally contribute cardiomyocytes to the heart.
    Authors: van Berlo J, Kanisicak O, Maillet M, Vagnozzi R, Karch J, Lin S, Middleton R, Marban E, Molkentin J
    Nature, 2014-05-07;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  95. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells.
    Authors: Toko, Haruhiro, Hariharan, Nirmala, Konstandin, Mathias, Ormachea, Lucia, McGregor, Michael, Gude, Natalie, Sundararaman, Balaji, Joyo, Eri, Joyo, Anya Y, Collins, Brett, Din, Shabana, Mohsin, Sadia, Uchida, Takafumi, Sussman, Mark A
    J Biol Chem, 2013-12-27;289(9):5348-56.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  96. Thymosin beta4 increases the potency of transplanted mesenchymal stem cells for myocardial repair.
    Authors: Ye L, Zhang P, Duval S, Su L, Xiong Q, Zhang J
    Circulation, 2013-09-10;128(11):S32-41.
    Species: Porcine
    Sample Types: Whole Tissue
    Applications: IHC-P
  97. Generation of Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial Stem Cell.
    Authors: Fang, Shentong, Wei, Jing, Pentinmikko, Nalle, Leinonen, Hannele, Salven, Petri
    PLoS Biol, 2012-10-16;10(10):e1001407.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  98. Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration.
    Authors: Nakamura-Ishizu A, Okuno Y, Omatsu Y, Okabe K, Morimoto J, Uede T, Nagasawa T, Suda T, Kubota Y
    Blood, 2012-05-02;119(23):5429-37.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  99. Microenvironmental regulation of inducible nitric oxide synthase expression and nitric oxide production in mouse bone marrow-derived mast cells.
    Authors: Moon TC, Yoshimura T, Parsons T, Befus AD
    J. Leukoc. Biol., 2012-01-18;91(4):581-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  100. Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization.
    Authors: Miyamoto K, Yoshida S, Kawasumi M
    J. Exp. Med., 2011-10-17;208(11):2175-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  101. CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6.
    Authors: Fifadara NH, Aye CC, Raghuwanshi SK, Richardson RM, Ono SJ
    Int. Immunol., 2009-07-10;21(8):991-1001.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  102. Harboring of particulate allergens within secretory compartments by mast cells following IgE/FcepsilonRI-lipid raft-mediated phagocytosis.
    Authors: Shin JS, Shelburne CP, Jin C, LeFurgey EA, Abraham SN
    J. Immunol., 2006-11-01;177(9):5791-800.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  103. FGF2-dependent mesenchyme and laminin-111 are niche factors in salivary gland organoids
    Authors: ZF Hosseini, DA Nelson, N Moskwa, LM Sfakis, J Castracane, M Larsen
    J. Cell. Sci., 2018-02-20;0(0):.
  104. CD11c regulates hematopoietic stem and progenitor cells under stress
    Authors: Lifei Hou, Richard A. Voit, Vijay G. Sankaran, Timothy A. Springer, Koichi Yuki
    Blood Advances
  105. The Wilms’ tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression
    Authors: Kay-Dietrich Wagner, Julien Cherfils-Vicini, Naoki Hosen, Peter Hohenstein, Eric Gilson, Nicholas D. Hastie et al.
    Nature Communications
  106. PDGFRa cells in mouse urinary bladder: A new class of interstitial cells.
    Authors: Koh BH, Roy R, Hollywood MAet al.
    J Cell Mol Med
  107. Modeling mammalian spermatogonial differentiation and meiotic initiation in vitro
    Authors: Oleksandr Kirsanov, Taylor Johnson, Taylor Malachowski, Bryan A. Niedenberger, Emma A. Gilbert, Debajit Bhowmick et al.
    Development
  108. Smchd1 is a maternal effect gene required for genomic imprinting
    Authors: Iromi Wanigasuriya, Quentin Gouil, Sarah A Kinkel, Andrés Tapia del Fierro, Tamara Beck, Ellise A Roper et al.
    eLife
  109. Resident c-kit(+) cells in the heart are not cardiac stem cells
    Authors: Nishat Sultana, Lu Zhang, Jianyun Yan, Jiqiu Chen, Weibin Cai, Shegufta Razzaque et al.
    Nature Communications
  110. Characterizing the Spermatogonial Response to Retinoic Acid During the Onset of Spermatogenesis and Following Synchronization in the Neonatal Mouse Testis1
    Authors: Kellie S. Agrimson, Jennifer Onken, Debra Mitchell, Traci B. Topping, Hélio Chiarini-Garcia, Cathryn A. Hogarth et al.
    Biology of Reproduction
  111. Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit
    Authors: Alcmène Chalazonitis, ZhiShan Li, Tuan D. Pham, Jason Chen, Meenakshi Rao, Päivi Lindholm et al.
    Journal of Comparative Neurology
  112. Vagal sensory innervation of the gastric sling muscle and antral wall: implications for gastro-esophageal reflux disease?
    Authors: Terry L. Powley, Jared M. Gilbert, Elizabeth A. Baronowsky, Cherie N. Billingsley, Felecia N. Martin, Robert J. Phillips
    Neurogastroenterology & Motility
  113. Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon
    Authors: Salah A Baker, Wesley A Leigh, Guillermo Del Valle, Inigo F De Yturriaga, Sean M Ward, Caroline A Cobine et al.
    eLife
  114. Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells
    Authors: KI Korski, DA Kubli, BJ Wang, FG Khalafalla, MM Monsanto, F Firouzi, OH Echeagaray, T Kim, RM Adamson, WP Dembitsky, ÅB Gustafsson, MA Sussman
    Stem Cells, 2019-01-30;0(0):.
  115. Electroacupuncture at ST36 Increases Bone Marrow-Derived Interstitial Cells of Cajal via the SDF-1/CXCR4 and mSCF/Kit-ETV1 Pathways in the Stomach of Diabetic Mice
    Authors: Jiao Zhao, Jing An, Shi Liu
    Evidence-Based Complementary and Alternative Medicine
  116. Morphologic and Immunohistochemical Characterization of Spontaneous Lymphoma/Leukemia in NSG Mice
    Authors: Heather Tillman, Laura J. Janke, Amy Funk, Peter Vogel, Jerold E. Rehg
    Veterinary Pathology

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Human/Mouse CD117/c-kit Antibody
By Anonymous on 10/26/2021
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Nerve tissue Species: Mouse

+4°C overnight incubation 1:200, 2nd anti-goat 647 1:400

Immunocytochemistry/Immunofluorescence Human/Mouse CD117/c-kit Antibody AF1356
Human/Mouse CD117/c-kit Antibody
By Anonymous on 10/02/2019
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult intestine Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse CD117/c-kit Antibody AF1356
Human/Mouse CD117/c-kit Antibody
By Anonymous on 06/12/2019
Application: WB Sample Tested: Muscle tissue Species: Mouse
Human/Mouse CD117/c-kit Antibody
By Mozhdeh Sojoodi on 05/07/2018
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Liver tissue Species: Rat

1:100 dilution
RT overnight incubation
Citrate buffer heat mediated antigen retrival

Immunocytochemistry/Immunofluorescence Human/Mouse CD117/c-kit Antibody AF1356
Human/Mouse CD117/c-kit Antibody
By Anonymous on 04/05/2018
Application: WB Sample Tested: ES-E14TG2a Species: Mouse

The experiment was performed on ES-E14TG2a cells: two different bands of about 130 KDa (< 135 KDa) were detected.

Western Blot Human/Mouse CD117/c-kit Antibody AF1356
Human/Mouse CD117/c-kit Antibody
By Anonymous on 07/24/2017
Application: WB Sample Tested: MCF 10A human breast epithelial cell line,MCF-7 human breast cancer cell line,MDA-MB-231 human breast cancer cell line Species: Human
Human/Mouse CD117/c-kit Antibody
By Zhiheng He on 08/08/2016
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Embryo tissue Species: Mouse

Mouse embryonic yolk sac tissue (E10.5), with 1:100 dilution, Alex Fluro 594 donkey anti-goat 2nd antibody with 1:400 dilution

Immunocytochemistry/Immunofluorescence Human/Mouse CD117/c-kit Antibody AF1356
Human/Mouse CD117/c-kit Antibody
By Anonymous on 03/22/2016
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Brain (basal ganglia) Species: Mouse