Human MMP-9 DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or equivalent
Reagent Diluent*
Blocking Buffer*
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990), or equivalent
Plate Sealers: ELISA Plate Sealers (Catalog # DY992), or equivalent
*For the Reagent Diluent and Blocking Buffer recommended for a specific DuoSet ELISA Development Kit, please see the product
Scientific Data
Product Datasheets
Preparation and Storage
Background: MMP-9
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
Citations for Human MMP-9 DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling
Authors: Cherpaz, M;Meugnier, E;Seillier, G;Pozzi, M;Pierrard, R;Leboube, S;Farhat, F;Vola, M;Obadia, JF;Amaz, C;Chalabreysse, L;May, C;Chanon, S;Brun, C;Givre, L;Bidaux, G;Mewton, N;Derumeaux, G;Bergerot, C;Paillard, M;Thibault, H;
Cardiovascular diabetology
Species: Human
Sample Types: Serum
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Implications of the Matrix Metalloproteinases, Their Tissue Inhibitors and Some Other Inflammatory Mediators Expression Levels in Children Obesity-Related Phenotypes
Authors: Wierzbicka-Ruci?ska, A;Kubiszewska, I;Grzywa-Czuba, R;Gackowska, L;Szalecki, M;Micha?kiewicz, J;Trojanek, JB;
Journal of personalized medicine
Species: Human
Sample Types: Cell Culture Supernates, Plasma
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Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
Authors: Zhu, W;Han, L;Wu, Y;Tong, L;He, L;Wang, Q;Yan, Y;Pan, T;Shen, J;Song, Y;Shen, Y;Zhu, Q;Zhou, J;
Respiratory research
Species: Transgenic Mouse, Mouse
Sample Types: Cell Culture Supernates
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CD40 Ligand-CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy
Authors: Abu El-Asrar, AM;Nawaz, MI;Ahmad, A;Dillemans, L;Siddiquei, M;Allegaert, E;Gikandi, PW;De Hertogh, G;Opdenakker, G;Struyf, S;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression
Authors: Zobel, CM;Wenzel, W;Krüger, JP;Baumgarten, U;Wagelöhner, T;Neumann, N;Foroutan, B;Müller, R;Müller, A;Rauschning, D;Schü beta ler, M;Scheit, L;Weinreich, F;Oltmanns, K;Keidel, F;Koch, M;Spethmann, S;Schreiner, M;
Frontiers in microbiology
Species: Human
Sample Types: Serum
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Secretomics reveals gelatinase substrates at the blood-brain barrier that are implicated in astroglial barrier function
Authors: Burmeister, M;Fraunenstein, A;Kahms, M;Arends, L;Gerwien, H;Deshpande, T;Kuhlmann, T;Gross, CC;Naik, VN;Wiendl, H;Klingauf, J;Meissner, F;Sorokin, L;
Science advances
Species: Human
Sample Types: CSF
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Serum TGF-?1 and CD14 Predicts Response to Anti-TNF-? Therapy in IBD
Authors: Coufal, S;Kverka, M;Kreisinger, J;Thon, T;Rob, F;Kolar, M;Reiss, Z;Schierova, D;Kostovcikova, K;Roubalova, R;Bajer, L;Jackova, Z;Mihula, M;Drastich, P;Tresnak Hercogova, J;Novakova, M;Vasatko, M;Lukas, M;Tlaskalova-Hogenova, H;Jiraskova Zakostelska, Z;
Journal of immunology research
Species: Human
Sample Types: Serum
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Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models
Authors: Rahman, M;Upadhyay, S;Ganguly, K;Introna, M;Ji, J;Boman, C;Muala, A;Blomberg, A;Sandström, T;Palmberg, L;
Toxics
Species: Human
Sample Types: Cell Culture Supernates
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Increased neutrophil derived chemokines (CXCL10 and CCL2) in human trichinellosis as possible serological markers of the polarization of the immune response against the parasite
Authors: F Bruschi, B Pinto, P Fallahi, SM Ferrari, A Antonelli
Cytokine, 2023-04-12;166(0):156205.
Species: Human
Sample Types: Serum
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Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation
Authors: M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi
Scientific Reports, 2023-03-21;13(1):4656.
Species: Human
Sample Types: Cell Culture Supernates
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Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis
Authors: M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi
PLoS ONE, 2023-01-20;18(1):e0280385.
Species: Human
Sample Types: Cell Culture Supernates
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Development of In Vitro Dry Eye Models to Study Proliferative and Anti-Inflammatory Effects of Allogeneic Serum Eye Drops
Authors: S Vo beta, T Behrmann, S Reichl
International Journal of Molecular Sciences, 2023-01-13;24(2):.
Species: Human
Sample Types: Cell Culture Supernates
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Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model
Authors: DT Spiegelbur, M Mannes, A Schultze, F Scheibenbe, F Müller, A Klitzing, DAC Messerer, K Nilsson Ek, B Nilsson, M Huber-Lang, CK Braun
PLoS ONE, 2023-01-12;18(1):e0280069.
Species: Human
Sample Types: Plasma
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Effects of Exercise Training on Neurotrophic Factors and Blood-Brain Barrier Permeability in Young-Old and Old-Old Women
Authors: SY Cho, HT Roh
International Journal of Environmental Research and Public Health, 2022-12-16;19(24):.
Species: Human
Sample Types: Serum
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Numerical modelling of WNT/beta-catenin signal pathway in characterization of EMT of colorectal carcinoma cell lines after treatment with Pt(IV) complexes
Authors: DS Šekli?, T ?uki?, D Milenkovi?, MM Jovanovi?, MN Živanovi?, Z Markovi?, N Filipovi?
Computer methods and programs in biomedicine, 2022-09-25;226(0):107158.
Species: Human
Sample Types: Cell Culture Supernates
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Mast Cell Proteases Promote Diverse Effects on the Plasminogen Activation System and Wound Healing in A549 Alveolar Epithelial Cells
Authors: S Mogren, F Berlin, L Eskilsson, N Van Der Bu, E Tufvesson, CK Andersson
Cells, 2022-09-18;11(18):.
Species: Human
Sample Types: BALF
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Clinical significance of�matrix metalloproteinase-9 in Fragile X Syndrome
Authors: A Laroui, L Galarneau, A Abolghasem, S Benachenho, R Plantefève, FZ Bouchouira, JF Lepage, F Corbin, A Çaku
Scientific Reports, 2022-09-13;12(1):15386.
Species: Human
Sample Types: Plasma
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IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation.
Authors: Kartasheva-Ebertz D, Gaston J, Lair-Mehiri L, Mottez E, Buivan T, Massault P, Scatton O, Gaujoux S, Vaillant J, Pol S, Lagaye S
Int J Mol Sci, 2022-08-29;23(17):.
Species: Human
Sample Types: Tissue Culture Supernates
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Growth Factor Release within Liquid and Solid PRF
Authors: K Zwittnig, B Kirnbauer, N Jakse, P Schlenke, I Mischak, S Ghanaati, S Al-Maawi, D Végh, M Payer, TA Zrnc
Journal of Clinical Medicine, 2022-08-29;11(17):.
Species: Human
Sample Types: Serum
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Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression
Authors: M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta
Cancers, 2022-07-13;14(14):.
Species: Human
Sample Types: Cell Culture Supernates
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Antenatal maternal depression, early life inflammation and neurodevelopment in a South African birth cohort
Authors: PJW Naudé, C Pariante, N Hoffman, SM Koopowitz, KA Donald, HJ Zar, DJ Stein
Brain, Behavior, and Immunity, 2022-07-06;105(0):160-168.
Species: Human
Sample Types: Serum
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A culture model to analyze the acute biomaterial-dependent reaction of human primary neutrophils in vitro
Authors: MA Wesdorp, A Schwab, EI Bektas, R Narcisi, D Eglin, MJ Stoddart, GJVM Van Osch, M D'Este
Oncogene, 2022-07-02;20(0):627-637.
Species: Human
Sample Types: Cell Culture Supernates
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Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models
Authors: S Upadhyay, A Chakrabort, TA Thimraj, M Baldi, A Steneholm, K Ganguly, P Gerde, L Ernstgård, L Palmberg
Oncogene, 2022-05-24;10(6):.
Species: Human
Sample Types: Cell Culture Supernates
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Mg-based materials diminish tumor spreading and cancer metastases
Authors: P Globig, R Madurawala, R Willumeit-, F Martini, E Mazzoni, BJC Luthringer
Bioactive materials, 2022-05-10;19(0):594-610.
Species: Human
Sample Types: Cell Culture Supernates
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A microphysiological model of human trophoblast invasion during implantation
Authors: JY Park, S Mani, G Clair, HM Olson, VL Paurus, CK Ansong, C Blundell, R Young, J Kanter, S Gordon, AY Yi, M Mainigi, DD Huh
Nature Communications, 2022-03-15;13(1):1252.
Species: Human
Sample Types: Cell Culture Supernates
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Neutrophils and lymphocytes in relation to MMP-8 and MMP-9 levels in pulmonary tuberculosis and HIV co-infection
Authors: B Alisjahban, N Sulastri, R Livia, L Apriani, AJ Verrall, E Sahiratmad
Journal of clinical tuberculosis and other mycobacterial diseases, 2022-03-04;27(0):100308.
Species: Human
Sample Types: Whole Blood
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Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length
Authors: S Hong, KH Park, YE Lee, JE Lee, YM Kim, E Joo, I Cho
PLoS ONE, 2022-02-07;17(2):e0263586.
Species: Human
Sample Types: Amniotic Fluid
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Trehangelins ameliorate inflammation-induced skin senescence by suppressing the epidermal YAP-CCN1 axis
Authors: M Yokota, Y Kamiya, T Suzuki, S Ishikawa, A Takeda, S Kondo, T Tohgasaki, T Nakashima, Y Takahashi, S ?mura, T Sakurai
Scientific Reports, 2022-01-19;12(1):952.
Species: Human
Sample Types: Cell Culture Supernates
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MMPs and TIMPs levels are correlated with anthropometric parameters, blood pressure, and endothelial function in obesity
Authors: S Boumiza, K Chahed, Z Tabka, MP Jacob, X Norel, G Ozen
Scientific Reports, 2021-10-08;11(1):20052.
Species: Human
Sample Types: Plasma
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Classical and Non-classical Fibrosis Phenotypes Are Revealed by Lung and Cardiac Like Microvascular Tissues On-Chip
Authors: A Akinbote, V Beltran-Sa, M Cherubini, R Visone, C Hajal, D Cobanoglu, K Haase
Frontiers in Physiology, 2021-10-06;12(0):735915.
Species: Human
Sample Types: Cell Culture Supernates
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Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate
Authors: RJ Weiss, PN Spahn, AWT Chiang, Q Liu, J Li, KM Hamill, S Rother, TM Clausen, MA Hoeksema, BM Timm, K Godula, CK Glass, Y Tor, PLSM Gordts, NE Lewis, JD Esko
Nature Chemical Biology, 2021-04-12;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Potential novel biomarkers for chronic lung allograft dysfunction and azithromycin responsive allograft dysfunction
Authors: C Veraar, J Kliman, A Benazzo, F Oberndorfe, M Laggner, P Hacker, T Raunegger, S Janik, P Jaksch, W Klepetko, HJ Ankersmit, B Moser
Scientific Reports, 2021-03-24;11(1):6799.
Species: Human
Sample Types: Serum
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The effects of resveratrol on the expression of VEGF, TGF-&beta, and MMP-9 in endometrial stromal cells of women with endometriosis
Authors: T Arablou, N Aryaeian, S Khodaverdi, R Kolahdouz-, Z Moradi, N Rashidi, AA Delbandi
Scientific Reports, 2021-03-15;11(1):6054.
Species: Human
Sample Types: Cell Culture Supernates
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A protein microarray analysis of amniotic fluid proteins for the prediction of spontaneous preterm delivery in women with preterm premature rupture of membranes at 23 to 30 weeks of gestation
Authors: HJ Kim, KH Park, YM Kim, E Joo, K Ahn, S Shin
PLoS ONE, 2020-12-31;15(12):e0244720.
Species: Human
Sample Types: Amniotic Fluid
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Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients
Authors: HK Pihlstrøm, T Ueland, AE Michelsen, P Aukrust, F Gatti, C Hammarströ, M Kasprzycka, J Wang, G Haraldsen, G Mjøen, DO Dahle, K Midtvedt, IA Eide, A Hartmann, H Holdaas
PLoS ONE, 2020-12-16;15(12):e0243759.
Species: Human
Sample Types: Plasma
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The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis
Authors: MA Rahat, M Safieh, E Simanovich, E Pasand, T Gazitt, A Haddad, M Elias, D Zisman
Arthritis Res Ther, 2020-10-14;22(1):240.
Species: Human
Sample Types: Serum
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Involvement of Matrix Metalloproteinase 9 in Vertebral Arterial Dissection With Posterior Circulation Ischemic Stroke
Authors: CY Chen, FC Chang, IH Lee, CP Chung
J Am Heart Assoc, 2020-09-12;0(0):e016743.
Species: Human
Sample Types: Plasma
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Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Peripheral Blood Leukocytes and Plasma of Children with Nonalcoholic Fatty Liver Disease
Authors: JB Trojanek, J Micha?kiew, R Grzywa-Czu, W Ja?czyk, L Gackowska, I Kubiszewsk, A Helmin-Bas, A Wierzbicka, M Szalecki, P Socha
Mediators Inflamm., 2020-09-10;2020(0):8327945.
Species: Human
Sample Types: Plasma
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Platelet-Released Growth Factors and Platelet-Rich Fibrin Induce Expression of Factors Involved in Extracellular Matrix Organization in Human Keratinocytes 22.39
Authors: A Bayer, B Wijaya, L Möbus, F Rademacher, M Rodewald, M Tohidnezha, T Pufe, D Drücke, R Gläser, J Harder
Int J Mol Sci, 2020-06-20;21(12):.
Species: Human
Sample Types: Cell Culture Supernates
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Plasma levels of matrix metalloproteinase-9 are elevated in individuals with hypertensive crisis
Authors: FM Valente, DO de Andrade, LN Cosenso-Ma, CB Cesarino, SM Guimarães, VB Guimarães, R Lacchini, JE Tanus-Sant, JC Yugar-Tole, JF Vilela-Mar
BMC Cardiovasc Disord, 2020-03-12;20(1):132.
Species: Human
Sample Types: Plasma
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Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in�vitro study using baicalein
Authors: CC Wu, YR Chen, DH Lu, LH Hsu, KC Yang, S Sumi
Regen Ther, 2020-02-24;14(0):177-183.
Species: Human
Sample Types: Cell Culture Supernates
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Immune and Inflammatory Proteins in Cord Blood as Predictive Biomarkers of Retinopathy of Prematurity in Preterm Infants
Authors: YJ Park, SJ Woo, YM Kim, S Hong, YE Lee, KH Park
Invest. Ophthalmol. Vis. Sci., 2019-09-03;60(12):3813-3820.
Species: Human
Sample Types: Plasma
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Inflammatory Bowel Disease Types Differ in Markers of Inflammation, Gut Barrier and in Specific Anti-Bacterial Response
Authors: S Coufal, N Galanova, L Bajer, Z Gajdarova, D Schierova, Z Jiraskova, K Kostovciko, Z Jackova, Z Stehlikova, P Drastich, H Tlaskalova, M Kverka
Cells, 2019-07-13;8(7):.
Species: Human
Sample Types: Serum
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Neutrophil Dysfunction in the Airways of Children with Acute Respiratory Failure Due to Lower Respiratory Tract Viral and Bacterial Coinfections
Authors: JR Grunwell, VD Giacalone, S Stephenson, C Margaroli, BS Dobosh, MR Brown, AM Fitzpatric, R Tirouvanzi
Sci Rep, 2019-02-27;9(1):2874.
Species: Human
Sample Types: Plasma
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Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst-Dependent Mechanism
Authors: RS Doster, JA Sutton, LM Rogers, DM Aronoff, JA Gaddy
MBio, 2018-11-20;9(6):.
Species: Human
Sample Types:
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Plasma inflammatory and immune proteins as predictors of intra-amniotic infection and spontaneous preterm delivery in women with preterm labor: a retrospective study
Authors: H Park, KH Park, YM Kim, SY Kook, SJ Jeon, HN Yoo
BMC Pregnancy Childbirth, 2018-05-09;18(1):146.
Species: Human
Sample Types: Plasma
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Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort
Authors: R Linder, E Rönmark, J Pourazar, AF Behndig, A Blomberg, A Lindberg
Respir. Res., 2018-04-12;19(1):64.
Species: Human
Sample Types: Serum
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Clinical predictors of liver fibrosis in patients with chronic hepatitis B virus infection from children to adults
Authors: JF Wu, SH Song, CS Lee, HL Chen, YH Ni, HY Hsu, TC Wu, MH Chang
J. Infect. Dis., 2018-04-11;0(0):.
Species: Human
Sample Types: Serum
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MicroRNA-320a protects against osteoarthritis cartilage degeneration by regulating the expressions of BMI-1 and RUNX2 in chondrocytes
Authors: H Peng, D Liang, B Li, C Liang, W Huang, H Lin
Pharmazie, 2017-04-01;72(4):223-226.
Species: Human
Sample Types: Cell Culture Supernates
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Serum Biomarkers of Myocardial Remodeling and Coronary Dysfunction in Early Stages of Hypertrophic Cardiomyopathy in the Young
Authors: E Fernlund, T Gyllenhamm, R Jablonowsk, M Carlsson, A Larsson, J Ärnlöv, P Liuba
Pediatr Cardiol, 2017-03-30;0(0):.
Species: Human
Sample Types: Serum
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Effect of selective small molecule inhibitors on MMP-9 and VEGFR-1 expression in p16-positive and -negative squamous cell carcinoma
Authors: B Kramer, JD Schultz, C Hock, A Sauter, BA Stuck, K Hörmann, R Birk, C Aderhold
Oncol Lett, 2017-03-13;13(5):3269-3276.
Species: Human
Sample Types: Cell Culture Supernates
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Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture
Authors: JW Park, KH Park, EY Jung
PLoS ONE, 2017-03-09;12(3):e0173312.
Species: Human
Sample Types: Amniotic Fluid
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Periodontitis and type 2 diabetes among women with previous gestational diabetes: epidemiological and immunological aspects in a follow-up of three years
Authors: RP Esteves Li, LO Cota, TA Silva, SC Cortelli, JR Cortelli, FO Costa
J Appl Oral Sci, 2017-03-01;25(2):130-139.
Species: Human
Sample Types: Saliva
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Evaluation of Association Between the Serum Levels of MMP-9 and MMP-9/TIMPs With Soluble Forms of Selectins and Itching Induced by Sulfur Mustard
Authors: N Askari, T Ghazanfari, MM Naghizadeh, A Moin, A Khamesipou, S Pourfarzam, ZM Hassan
Iran J Pathol, 2017-01-27;12(3):257-264.
Species: Human
Sample Types: Serum
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Development of Combining of Human Bronchial Mucosa Models with XposeALI? for Exposure of Air Pollution Nanoparticles
Authors: J Ji, A Hedelin, M Malml”f, V Kessler, G Seisenbaev, P Gerde, L Palmberg
PLoS ONE, 2017-01-20;12(1):e0170428.
Species: Human
Sample Types: Cell Culture Supernates
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Serological signatures of clinical cure following successful treatment with sodium stibogluconate in Ethiopian visceral leishmaniasis
Cytokine, 2016-12-08;91(0):6-9.
Species: Human
Sample Types: Serum
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Association of Matrix Metalloproteinases -7, -8 and -9 and TIMP -1 with Disease Severity in Acute Pancreatitis. A Cohort Study
PLoS ONE, 2016-08-25;11(8):e0161480.
Species: Human
Sample Types: Plasma
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In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
Reprod Biol Endocrinol, 2015-10-07;13(0):115.
Species: Human
Sample Types: Cell Culture Supernates
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Serum metalloproteinase-9 is related to COPD severity and symptoms - cross-sectional data from a population based cohort-study.
Authors: Linder R, Ronmark E, Pourazar J, Behndig A, Blomberg A, Lindberg A
Respir Res, 2015-02-21;16(0):28.
Species: Human
Sample Types: Serum
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Therapy with plasma purified alpha1-antitrypsin (Prolastin(R)) induces time-dependent changes in plasma levels of MMP-9 and MPO.
Authors: Koepke J, Dresel M, Schmid S, Greulich T, Beutel B, Schmeck B, Vogelmeier C, Janciauskiene S, Koczulla A
PLoS ONE, 2015-01-30;10(0):.
Species: Human
Sample Types: Serum
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Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens.
Authors: Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, Podgorska M, Smola S, Hoth M, Zufall F
J Biol Chem, 2015-01-20;290(12):7369-87.
Species: Human
Sample Types: Cell Culture Supernates
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Identification of neutrophil activation markers as novel surrogate markers of CF lung disease.
Authors: Rath T, Zwaschka L, Hage L, Kugler M, Menendez K, Naehrlich L, Schulz R, Roderfeld M, Roeb E
PLoS ONE, 2014-12-29;9(12):e115847.
Species: Human
Sample Types: Serum
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A novel nonhuman primate model of cigarette smoke-induced airway disease.
Authors: Polverino F, Doyle-Eisele M, McDonald J, Wilder J, Royer C, Laucho-Contreras M, Kelly E, Divo M, Pinto-Plata V, Mauderly J, Celli B, Tesfaigzi Y, Owen C
Am J Pathol, 2014-12-24;185(3):741-55.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: BALF
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Compartment differences of inflammatory activity in chronic obstructive pulmonary disease.
Authors: Ji J, von Scheele I, Bergstrom J, Billing B, Dahlen B, Lantz A, Larsson K, Palmberg L
Respir Res, 2014-08-26;15(0):104.
Species: Human
Sample Types: Serum
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Controlled and uncontrolled asthma display distinct alveolar tissue matrix compositions.
Authors: Weitoft M, Andersson C, Andersson-Sjoland A, Tufvesson E, Bjermer L, Erjefalt J, Westergren-Thorsson G
Respir Res, 2014-06-20;15(0):67.
Species: Human
Sample Types: BALF
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Clinical utility of diagnostic guidelines and putative biomarkers in lymphangioleiomyomatosis.
Respir. Res., 2012-04-18;13(0):34.
Species: Human
Sample Types: Serum
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Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9.
Authors: Chambers MA, Whelan AO, Spallek R
Biochem. Biophys. Res. Commun., 2010-08-26;400(3):403-8.
Species: Human
Sample Types: Cell Culture Supernates
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Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages.
Authors: Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, Ponsoda S, Delneste Y, Hebbar M, Jeannin P
Int. J. Cancer, 2009-07-15;125(2):367-73.
Species: Human
Sample Types: Cell Culture Supernates
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Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis.
Authors: Kuenz B, Lutterotti A, Ehling R, Gneiss C, Haemmerle M, Rainer C, Deisenhammer F, Schocke M, Berger T, Reindl M
PLoS ONE, 2008-07-02;3(7):e2559.
Species: Human
Sample Types: Serum
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Matrix metalloproteinases and their tissue inhibitors (TIMPs) in Plasmodium falciparum malaria: serum levels of TIMP-1 are associated with disease severity.
Authors: Dietmann A, Helbok R, Lackner P, Issifou S, Lell B, Matsiegui PB, Reindl M, Schmutzhard E, Kremsner PG
J. Infect. Dis., 2008-06-01;197(11):1614-20.
Species: Human
Sample Types: Serum
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Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.
Authors: Tsai HC, Chung LY, Chen ER, Sy CL
Am. J. Trop. Med. Hyg., 2008-01-01;78(1):20-7.
Species: Human
Sample Types: CSF
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Dermal fibroblast cell culture supernatant following stimulation with 2ng/mL TGFb1
We ran human EDTA plasma at a 1:400 dilution for this assay. The kit performed ideally with high precision and satisfaction.