Human KIR3DL3/CD158z (AAC99763) VersaClone cDNA

Catalog #: RDC0575 Datasheet / COA / SDS

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RDC0575

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Human KIR3DL3/CD158z (AAC99763) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: KIR3DL3/CD158z

The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.

Long Name

Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 3

Entrez Gene IDs

115653 (Human)

Alternate Names

CD158z; CD158Z;Killer cell immunoglobulin-like receptor 3DL3;KIR2DL5B;KIR3DL7;KIR44;KIRC1; KIR3DL3; KIR3DL7; KIR44; KIRC1

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