Human IL-6 DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human IL-6. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Scientific Data
Product Datasheets
Preparation and Storage
Background: IL-6
Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.
IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor.
IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Human IL-6 DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling
Authors: Jacobs, MME;Maas, RJF;Jonkman, I;Negishi, Y;Tielemans Zamora, W;Yanginlar, C;van Heck, J;Matzaraki, V;Martens, JHA;Baltissen, M;Vermeulen, M;Morla-Folch, J;Ranzenigo, A;Wang, W;Umali, M;Ochando, J;van der Vlag, J;Hilbrands, LB;Joosten, LAB;Netea, MG;Mulder, WJM;van Leent, MMT;Mhlanga, MM;Teunissen, AJP;Rother, N;Duivenvoorden, R;
Cell reports
Species: Human
Sample Types: Cell Culture Supernates
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Exploring the potency of polyphenol-rich blend from Lonicera caerulea var. Kamtschatica sevast., Aronia melanocarpa, and Echinacea purpurea: Promising anti-inflammatory, antioxidant, and antiviral properties
Authors: Zima, K;Khaidakov, B;Sochocka, M;Ochnik, M;Lemke, K;Kowalczyk, P;
Heliyon
Species: Human
Sample Types: Cell Culture Supernates
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Endoplasmic Reticulum Stress Differently Modulates the Release of IL-6 and IL-8 Cytokines in Human Glial Cells
Authors: Soko?owska, P;Wiktorowska-Owczarek, A;Tambor, J;Gawlak-Socka, S;Kowalczyk, E;Jó?wiak-B?benista, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading
Authors: Yadav, P;Ortega, JG;Tamaki, W;Chien, C;Chang, KC;Biswas, N;Pan, S;Nilsson, J;Yin, X;Bhattacharyya, A;Boostanpour, K;Jujaray, T;Wang, J;Tsukui, T;Sheppard, D;Li, B;Maishan, M;Taenaka, H;Matthay, MA;Muramatsu, R;Maliskova, L;Ghosh, A;Eckalbar, WL;Molofsky, AB;Wolters, PJ;Tamaki, SJ;Bivona, T;Abate, AR;Wagner, A;Tharp, KM;Bhattacharya, M;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Cell Culture Supernates
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Anti-Inflammatory and Antioxidant Properties of a New Mixture of Vitamin C, Collagen Peptides, Resveratrol, and Astaxanthin in Tenocytes: Molecular Basis for Future Applications in Tendinopathies
Authors: Marzagalli, M;Battaglia, S;Raimondi, M;Fontana, F;Cozzi, M;Ranieri, FR;Sacchi, R;Curti, V;Limonta, P;
Mediators of inflammation
Species: Human
Sample Types: Cell Culture Supernates
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Loss of Tuberous Sclerosis Complex 2 confers inflammation via dysregulation of Nuclear factor kappa-light-chain-enhancer of activated B cells
Authors: McPhail, DK;Alzahrani, MAM;Martin, KR;Calver, BL;Harwood, AJ;MacKeigan, JP;Davies, DM;Tee, AR;
Research square
Species: Human
Sample Types: Cell Culture Supernates
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Effect of progestin-based contraceptives on HIV-associated vaginal immune biomarkers and microbiome in adolescent girls
Authors: Nasr, MA;Aldous, A;Daniels, J;Joy, C;Capozzi, E;Yang, M;Moriarty, P;Emmanuel-Baker, V;Malcolm, S;Green, SJ;Gomez-Lobo, V;Ghosh, M;
PloS one
Species: Human
Sample Types: Vaginal Swab
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Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling
Authors: Cherpaz, M;Meugnier, E;Seillier, G;Pozzi, M;Pierrard, R;Leboube, S;Farhat, F;Vola, M;Obadia, JF;Amaz, C;Chalabreysse, L;May, C;Chanon, S;Brun, C;Givre, L;Bidaux, G;Mewton, N;Derumeaux, G;Bergerot, C;Paillard, M;Thibault, H;
Cardiovascular diabetology
Species: Human
Sample Types: Serum
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Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination
Authors: Cab?u, G;Badii, M;Mirea, AM;Gaal, OI;van Emst, L;Popp, RA;Cri?an, TO;Joosten, LAB;
Vaccines
Species: Human
Sample Types: Cell Culture Supernates
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A Synthetic Small Molecule, LGM2605: A Promising Modulator of Increased Pro-Inflammatory Cytokine and Osteoclast Differentiation by Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin
Authors: Kim, TJ;MacElroy, AS;Defreitas, A;Shenker, BJ;Boesze-Battaglia, K;
Dentistry journal
Species: Human
Sample Types: Cell Culture Supernates
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Identification and characterization of plasma proteins associated with intra-amniotic inflammation and/or infection in women with preterm labor.
Authors: Cho, HY;Lee, JE;Park, KH;Choi, BY;Lee, MJ;Jeong, DE;Shin, S;
Scientific reports
Species: Human
Sample Types: Amniotic Fluid
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A plug-and-play, easy-to-manufacture fluidic accessory to significantly enhance the sensitivity of electrochemical immunoassays
Authors: Dobrea, A;Hall, N;Milne, S;Corrigan, DK;Jimenez, M;
Scientific reports
Species: Human, N/A
Sample Types: Serum, Plasma, Buffer
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Structural characterization of a proanthocyanidin-rich fraction from Hancornia speciosa leaves and its effect on the release of pro-inflammatory cytokines and oxidative stress in THP-1 cells
Authors: Carneiro Junior, WO;Guimarães, MLR;Freitas, KM;Pereira, RS;Pádua, RM;Campana, PRV;Braga, FC;
Journal of ethnopharmacology
Species: Human
Sample Types: Cell Culture Supernates
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Nuclear factor-?B activation by transforming growth factor-?1 drives tumour microenvironment-mediated drug resistance in neuroblastoma
Authors: Louault, K;Blavier, L;Lee, MH;Kennedy, RJ;Fernandez, GE;Pawel, BR;Asgharzadeh, S;DeClerck, YA;
British journal of cancer
Species: Human
Sample Types: Cell Culture Supernates
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Octyl itaconate enhances VSV?51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Authors: Kurmasheva, N;Said, A;Wong, B;Kinderman, P;Han, X;Rahimic, AHF;Kress, A;Carter-Timofte, ME;Holm, E;van der Horst, D;Kollmann, CF;Liu, Z;Wang, C;Hoang, HD;Kovalenko, E;Chrysopoulou, M;Twayana, KS;Ottosen, RN;Svenningsen, EB;Begnini, F;Kiib, AE;Kromm, FEH;Weiss, HJ;Di Carlo, D;Muscolini, M;Higgins, M;van der Heijden, M;Bardoul, A;Tong, T;Ozsvar, A;Hou, WH;Schack, VR;Holm, CK;Zheng, Y;Ruzek, M;Kalucka, J;de la Vega, L;Elgaher, WAM;Korshoej, AR;Lin, R;Hiscott, J;Poulsen, TB;O'Neill, LA;Roy, DG;Rinschen, MM;van Montfoort, N;Diallo, JS;Farin, HF;Alain, T;Olagnier, D;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
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Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation
Authors: Marinho, A;Seabra, CL;Lima, SAC;Lobo-da-Cunha, A;Reis, S;Nunes, C;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Using the Traditional Ex Vivo Whole Blood Model to Discriminate Bacteria by Their Inducible Host Responses
Authors: Chick, HM;Rees, ME;Lewis, ML;Williams, LK;Bodger, O;Harris, LG;Rushton, S;Wilkinson, TS;
Biomedicines
Species: Human
Sample Types: Whole Blood
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Interpersonal violence exposure and inflammation during adolescence and young adulthood
Authors: Finegood, ED;Weissman-Tsukamoto, R;Lam, P;Chen, E;Miller, GE;
Psychoneuroendocrinology
Species: Human
Sample Types: Plasma
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Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
Authors: Dos Santos, JC;Moreno, M;Teufel, LU;Chilibroste, S;Keating, ST;Groh, L;Domínguez-Andrés, J;Williams, DL;Ma, Z;Lowman, DW;Ensley, HE;Novakovic, B;Ribeiro-Dias, F;Netea, MG;Chabalgoity, JA;Joosten, LAB;
Cell reports
Species: Human
Sample Types: Cell Culture Supernates
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Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis
Authors: Li, Y;Nie, Y;Yang, X;Liu, Y;Deng, X;Hayashi, Y;Plummer, R;Li, Q;Luo, N;Kasai, T;Okumura, T;Kamishibahara, Y;Komoto, T;Ohkuma, T;Okamoto, S;Isobe, Y;Yamaguchi, K;Furukawa, Y;Taniguchi, H;
Cell reports
Species: Human
Sample Types: Cell Culture Supernates
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The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages
Authors: Assis, SIS;Amendola, LS;Okamoto, MM;Ferreira, GDS;Iborra, RT;Santos, DR;Santana, MFM;Santana, KG;Correa-Giannella, ML;Barbeiro, DF;Soriano, FG;Machado, UF;Passarelli, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Reduced Glycolysis and Cytotoxicity in Staphylococcus aureus Isolates from Chronic Rhinosinusitis as Strategies for Host Adaptation
Authors: Tuchscherr, L;Wendler, S;Santhanam, R;Priese, J;Reissig, A;Müller, E;Ali, R;Müller, S;Löffler, B;Monecke, S;Ehricht, R;Guntinas-Lichius, O;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
Authors: Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL;
Proceedings of the National Academy of Sciences of the United States of America
Species: Human
Sample Types: Cell Culture Supernates
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Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection
Authors: Mestriner, F;Francisco, DF;Campos, LCB;Couto, AES;Fraga-Silva, TFC;Flora Dugaich, V;D Avila-Mesquita, C;Zukowski Kovacs, H;Vasconcelos, JL;Milani, ER;Santos Guedes de Sá, K;Martins, R;Jordani, MC;Corsi, CAC;Barbosa, JM;Vasconcelos, T;Gonçalves Menegueti, M;Neto, J;da Costa, RM;Evora, PRB;Arruda, E;Tostes, R;Polonis, K;Bonato, VLD;Auxiliadora-Martins, M;Ribeiro, MS;Becari, C;
Cytokine
Species: Human
Sample Types: Cell Culture Supernates
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Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial
Authors: Vicariotto, F;Malfa, P;Viciani, E;Dell'Atti, F;Squarzanti, DF;Marcante, A;Castagnetti, A;Ponchia, R;Governini, L;De Leo, V;
Nutrients
Species: Human
Sample Types: Vaginal Swab
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Circulating Adipocytokines and Insulin Like-Growth Factors and Their Modulation in Obesity-Associated Endometrial Cancer
Authors: Ray, I;Möller-Levet, CS;Michael, A;Butler-Manuel, S;Chatterjee, J;Tailor, A;Ellis, PE;Meira, LB;
Cancers
Species: Human
Sample Types: Plasma
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Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Microenvironment in De Novo AML Patients
Authors: Bo?kun, ?;Starosz, A;Kr?towska-Grunwald, A;Wasiluk, T;Walewska, A;Wierzbowska, A;Moniuszko, M;Grubczak, K;
Cancers
Species: Human
Sample Types: Cell Culture Supernates
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Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?
Authors: Kuçi, Z;Piede, N;Vogelsang, K;Pfeffermann, LM;Wehner, S;Salzmann-Manrique, E;Stais, M;Kreyenberg, H;Bonig, H;Bader, P;Kuçi, S;
Journal of translational medicine
Species: Human
Sample Types: Cell Culture Supernates
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iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotype
Authors: Sullivan, MA;Lane, SD;McKenzie, ADJ;Ball, SR;Sunde, M;Neely, GG;Moreno, CL;Maximova, A;Werry, EL;Kassiou, M;
Journal of neuroinflammation
Species: Human
Sample Types: Cell Culture Supernates
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Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis
Authors: Kim, YT;Huh, JW;Choi, YH;Yoon, HK;Nguyen, TT;Chun, E;Jeong, G;Park, S;Ahn, S;Lee, WK;Noh, YW;Lee, KS;Ahn, HS;Lee, C;Lee, SM;Kim, KS;Suh, GJ;Jeon, K;Kim, S;Jin, M;
EMBO molecular medicine
Species: Mouse
Sample Types: Plasma, Peritoneal Lavage Fluid
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High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification
Authors: Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A;
Biomolecules
Species: Human
Sample Types: Cell Culture Supernates
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Impact of microgravity on a three-dimensional microphysiologic culture of the human kidney proximal tubule epithelium: cell response to serum and vitamin D
Authors: Kelly, E;Lindberg, K;Jones-Isaac, K;Yang, J;Bain, J;Wang, L;MacDonald, J;Bammler, T;Calamia, J;Thummel, K;Yeung, C;Countryman, S;Koenig, P;Himmelfarb, J;
Research square
Species: Human
Sample Types: Serum
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Leptin-Mediated Induction of IL-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis
Authors: Ozmen, A;Nwabuobi, C;Tang, Z;Guo, X;Larsen, K;Guller, S;Blas, J;Moore, M;Kayisli, UA;Lockwood, CJ;Guzeloglu-Kayisli, O;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Investigation of the structural and immunomodulatory properties of alkali-soluble ?-glucans from Pleurotus eryngii fruiting bodies
Authors: Ellefsen, CF;Lindstad, L;Klau, LJ;Aachmann, FL;Hiorth, M;Samuelsen, ABC;
Carbohydrate polymers
Species: Human
Sample Types: Cell Culture Supernates
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?-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling
Authors: Kim, HS;Kim, HJ;Hong, YD;Son, ED;Cho, SY;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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Soluble CD137: A Potential Prognostic Biomarker in Critically Ill Patients
Authors: Räth, U;Mester, P;Schwarz, H;Schmid, S;Müller, M;Buechler, C;Pavel, V;
International journal of molecular sciences
Species: Human
Sample Types: Plasma
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Cognitive dysfunction in systemic lupus erythematosus is associated with disease activity and oxidative stress: a comparative study with rheumatoid arthritis for identifying biomarkers
Authors: de Sousa, DC;Sobreira, EST;Feitosa, WLQ;Aires, TMPM;Araújo, LPP;Silva, ALC;Joventino, CB;Silveira, NMT;Chaves-Filho, AJM;Macêdo, DS;Braga-Neto, P;
BMC neuroscience
Species: Human
Sample Types: Plasma
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The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis
Authors: Elhai, M;Micheroli, R;Houtman, M;Mirrahimi, M;Moser, L;Pauli, C;Bürki, K;Laimbacher, A;Kania, G;Klein, K;Schätzle, P;Bertoncelj, MF;Edalat, SG;Keusch, L;Khmelevskaya, A;Toitou, M;Geiss, C;Rauer, T;Sakkou, M;Kollias, G;Armaka, M;Distler, O;Ospelt, C;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
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Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases
Authors: Wu, WC;Shiu, C;Tong, TK;Leung, SO;Hui, CW;
Journal of immunology research
Species: Human
Sample Types: Cell Culture Supernates
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Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin
Authors: Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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Acid ceramidase regulates innate immune memory
Authors: Rother, N;Yanginlar, C;Prévot, G;Jonkman, I;Jacobs, M;van Leent, MMT;van Heck, J;Matzaraki, V;Azzun, A;Morla-Folch, J;Ranzenigo, A;Wang, W;van der Meel, R;Fayad, ZA;Riksen, NP;Hilbrands, LB;Lindeboom, RGH;Martens, JHA;Vermeulen, M;Joosten, LAB;Netea, MG;Mulder, WJM;van der Vlag, J;Teunissen, AJP;Duivenvoorden, R;
Cell reports
Species: Human
Sample Types: Cell Culture Supernates
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Functional genome analysis and anti-Helicobacter pylori activity of a novel bacteriocinogenic Lactococcus sp. NH2-7C from Thai fermented pork (Nham)
Authors: Kingkaew, E;Woraprayote, W;Booncharoen, A;Niwasabutra, K;Janyaphisan, T;Vilaichone, RK;Yamaoka, Y;Visessanguan, W;Tanasupawat, S;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection
Authors: Cholon, DM;Greenwald, MA;Higgs, MG;Quinney, NL;Boyles, SE;Meinig, SL;Minges, JT;Chaubal, A;Tarran, R;Ribeiro, CMP;Wolfgang, MC;Gentzsch, M;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial
Authors: Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D;
PloS one
Species: Human
Sample Types: Serum
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Human PBMCs Form Lipid Droplets in Response to Spike Proteins
Authors: Sivaraman, K;Pino, P;Raussin, G;Anchisi, S;Metayer, C;Dagany, N;Held, J;Wrenger, S;Welte, T;Wurm, MJ;Wurm, FM;Olejnicka, B;Janciauskiene, S;
Microorganisms
Species: Human
Sample Types: Cell Culture Supernates
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Unrevealed roles of extracellular enolase?1 (ENO1) in promoting glycolysis and pro?cancer activities in multiple myeloma via hypoxia?inducible factor 1?
Authors: Chung, IC;Huang, WC;Huang, YT;Chen, ML;Tsai, AW;Wu, PY;Yuan, TT;
Oncology reports
Species: Human, Mouse
Sample Types: Cell Culture Supernates
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Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV
Authors: Sereti, I;Verburgh, ML;Gifford, J;Lo, A;Boyd, A;Verheij, E;Verhoeven, A;Wit, FWNM;Schim van der Loeff, MF;Giera, M;Kootstra, NA;Reiss, P;Vujkovic-Cvijin, I;
Cell reports
Species: Human
Sample Types: Plasma
-
Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health
Authors: Campesi, I;Capobianco, G;Cano, A;Lodde, V;Cruciani, S;Maioli, M;Sotgiu, G;Idda, ML;Puci, MV;Ruoppolo, M;Costanzo, M;Caterino, M;Cambosu, F;Montella, A;Franconi, F;
Biomedicines
Species: Human
Sample Types: Amniotic Fluid
-
The effect of leptin on trained innate immunity and on systemic inflammation in subjects with obesity
Authors: Flores Gomez, D;Bekkering, S;Horst, RT;Cossins, B;van den Munckhof, ICL;Rutten, JHW;Joosten, LAB;Netea, MG;Riksen, NP;
Journal of leukocyte biology
Species: Human
Sample Types: Cell Culture Supernates
-
Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties
Authors: Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T;
International immunopharmacology
Species: Human
Sample Types: Cell Culture Supernates
-
Efficient symptomatic treatment and viral load reduction for children with influenza virus infection by nasal-spraying Bacillus spore probiotics
Authors: Tran, TT;Phung, TTB;Tran, DM;Bui, HT;Nguyen, PTT;Vu, TT;Ngo, NTP;Nguyen, MT;Nguyen, AH;Nguyen, ATV;
Scientific reports
Species: Human
Sample Types: Nasopharyngeal aspirate
-
TNF-? and Poly(I:C) induction of A20 and activation of NF-?B signaling are independent of ABCF1 in human airway epithelial cells
Authors: Cao, QT;Ishak, M;Shpilman, I;Hirota, JA;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
-
TNF? induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function
Authors: Twarog, M;Schustak, J;Xu, Y;Coble, M;Dolan, K;Esterberg, R;Huang, Q;Saint-Geniez, M;Bao, Y;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates, Cell Lysates
-
TNF? is a key trigger of inflammation in diet-induced non-obese MASLD in mice
Authors: Burger, K;Jung, F;Baumann, A;Brandt, A;Staltner, R;Sánchez, V;Bergheim, I;
Redox biology
Species: Human
Sample Types: Tissue Homogenates
-
SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication
Authors: Montezano, AC;Camargo, LL;Mary, S;Neves, KB;Rios, FJ;Stein, R;Lopes, RA;Beattie, W;Thomson, J;Herder, V;Szemiel, AM;McFarlane, S;Palmarini, M;Touyz, RM;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
-
Size- and oxidative potential-dependent toxicity of environmentally relevant expanded polystyrene styrofoam microplastics to macrophages
Authors: Jeon, S;Jeon, JH;Jeong, J;Kim, G;Lee, S;Kim, S;Maruthupandy, M;Lee, K;Yang, SI;Cho, WS;
Journal of hazardous materials
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of bile salt-stimulated lipase on blood cells and associations with disease activity in human inflammatory joint disorders
Authors: Lindquist, S;Wang, Y;Andersson, EL;Tsuji Grebe, S;Alenius, GM;Rantapää-Dahlqvist, S;Lundberg, L;Hernell, O;
PloS one
Species: Human
Sample Types: Serum
-
The influence of calcitriol and methylprednisolone on podocytes function in minimal change disease in vitro model
Authors: Grubczak, K;Starosz, A;Makowska, B;Parfienowicz, Z;Kr?towska, M;Naumnik, B;Moniuszko, M;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernatants
-
Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions
Authors: Faria, J;Ahmed, S;Stamatialis, D;Verhaar, MC;Masereeuw, R;Gerritsen, KGF;Mih?il?, SM;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
-
Supersulphides provide airway protection in viral and chronic lung diseases
Authors: Matsunaga, T;Sano, H;Takita, K;Morita, M;Yamanaka, S;Ichikawa, T;Numakura, T;Ida, T;Jung, M;Ogata, S;Yoon, S;Fujino, N;Kyogoku, Y;Sasaki, Y;Koarai, A;Tamada, T;Toyama, A;Nakabayashi, T;Kageyama, L;Kyuwa, S;Inaba, K;Watanabe, S;Nagy, P;Sawa, T;Oshiumi, H;Ichinose, M;Yamada, M;Sugiura, H;Wei, FY;Motohashi, H;Akaike, T;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
-
Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells
Authors: Zhou, L;Fang, L;Tamm, M;Stolz, D;Roth, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
-
Comparison of the effects of high-intensity interval and moderate-intensity continuous training on inflammatory markers, cardiorespiratory fitness, and quality of life in breast cancer patients
Authors: Isanejad, A;Nazari, S;Gharib, B;Motlagh, AG;
Journal of sport and health science
Species: Human
Sample Types: Serum
-
Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells
Authors: Kalsi, KK;Jackson, S;Baines, DL;
PloS one
Species: Human
Sample Types: Cell Culture Supernates
-
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli
Authors: Malaga, W;Payros, D;Meunier, E;Frigui, W;Sayes, F;Pawlik, A;Orgeur, M;Berrone, C;Moreau, F;Mazères, S;Gonzalo-Asensio, J;Rengel, D;Martin, C;Astarie-Dequeker, C;Mourey, L;Brosch, R;Guilhot, C;
PLoS pathogens
Species: Human
Sample Types: Cell Culture Supernates
-
Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones Conjugated with Proteinogenic Amino Acids
Authors: Vieira, SF;Araújo, J;Gonçalves, VMF;Fernandes, C;Pinto, M;Ferreira, H;Neves, NM;Tiritan, ME;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
-
Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype
Authors: Warren, KJ;Beck, EM;Callahan, SJ;Helms, MN;Middleton, E;Maddock, S;Carr, JR;Harris, D;Blagev, DP;Lanspa, MJ;Brown, SM;Paine, R;
Respiratory research
Species: Human
Sample Types: BALF
-
Dimethyl itaconate induces long-term innate immune responses and confers protection against infection
Authors: Ferreira, AV;Kostidis, S;Groh, LA;Koeken, VACM;Bruno, M;Baydemir, I;Kilic, G;Bulut, Ö;Andriopoulou, T;Spanou, V;Synodinou, KD;Gkavogianni, T;Moorlag, SJCFM;Charlotte de Bree, L;Mourits, VP;Matzaraki, V;Koopman, WJH;van de Veerdonk, FL;Renieris, G;Giera, M;Giamarellos-Bourboulis, EJ;Novakovic, B;Domínguez-Andrés, J;
Cell reports
Species: Human
Sample Types: Cell Culture Supenates
-
COVID-19 vaccination exacerbates ex vivo IL-6 release from isolated PBMCs
Authors: Langgartner, D;Winkler, R;Brunner-Weisser, J;Rohleder, N;Jarczok, MN;Gündel, H;Weimer, K;Reber, SO;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
-
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), somatic and fatigue symptoms in cardiovascular diseases comorbid major depressive disorder (MDD): A randomized controlled trial
Authors: Chang, JP;Chang, SS;Chen, HT;Chien, YC;Yang, HT;Huang, SY;Tseng, PT;Chang, CH;Galecki, P;Su, KP;
Brain, behavior, and immunity
Species: Human
Sample Types: Plasma
-
Efficacy of Cooling Centers for Mitigating Physiological Strain in Older Adults during Daylong Heat Exposure: A Laboratory-Based Heat Wave Simulation
Authors: Meade, RD;Notley, SR;Akerman, AP;McCormick, JJ;King, KE;Sigal, RJ;Kenny, GP;
Environmental health perspectives
Species: Human
Sample Types: Serum
-
In vitro effects of undifferentiated callus extracts from Plantago major L, Rhodiola rosea L and Silybum marianum L in normal and malignant human skin cells
Authors: Gjörloff Wingren, A;Ziyad Faik, R;Holefors, A;Filecovic, E;Gustafsson, A;
Heliyon
Species: Human
Sample Types: Cell Culture Supernates
-
Impact of Enzymatically Extracted High Molecular Weight Fucoidan on Lipopolysaccharide-Induced Endothelial Activation and Leukocyte Adhesion
Authors: Kirsten, N;Ohmes, J;Mikkelsen, MD;Nguyen, TT;Blümel, M;Wang, F;Tasdemir, D;Seekamp, A;Meyer, AS;Fuchs, S;
Marine drugs
Species: Human
Sample Types: Cell Culture Supernates
-
Preliminary Study on the Effect of a Night Shift on Blood Pressure and Clock Gene Expression
Authors: Toffoli, B;Tonon, F;Giudici, F;Ferretti, T;Ghirigato, E;Contessa, M;Francica, M;Candido, R;Puato, M;Grillo, A;Fabris, B;Bernardi, S;
International journal of molecular sciences
Species: Human
Sample Types: Plasma
-
Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-? expression in TNF-?/IFN-?-stimulated human keratinocytes
Authors: Jeon, KB;Kim, J;Lim, CM;Park, JY;Kim, NY;Lee, J;Oh, DK;Yoon, DY;
International immunopharmacology
Species: Human
Sample Types: Cell Culture Supernates
-
Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction
Authors: Li, C;Ture, SK;Nieves-Lopez, B;Blick-Nitko, SK;Maurya, P;Livada, AC;Stahl, TJ;Kim, M;Pietropaoli, AP;Morrell, CN;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Cell Culture Supernates
-
Influence of dose and exposition time in the effectiveness of N-Acetyl-l-cysteine treatment in A549 human epithelial cells
Authors: Montero, P;Roger, I;Estornut, C;Milara, J;Cortijo, J;
Heliyon
Species: Human
Sample Types: Cell Culture Supernates
-
Diabetes increases mortality in patients with pancreatic and colorectal cancer by promoting cachexia and its associated inflammatory status
Authors: A Chovsepian, O Prokopchuk, G Petrova, T Gjini, H Kuzi, S Heisz, KP Janssen, ME Martignoni, H Friess, H Hauner, M Rohm
Molecular Metabolism, 2023-04-22;0(0):101729.
Species: Human
Sample Types: Plasma
-
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration
Authors: P Banerjee, AR Mehta, RS Nirujogi, J Cooper, OG James, J Nanda, J Longden, K Burr, K McDade, A Salzinger, E Paza, J Newton, D Story, S Pal, C Smith, DR Alessi, BT Selvaraj, J Priller, S Chandran
Science Advances, 2023-04-21;9(16):eabq0651.
Species: Human
Sample Types: Cell Culture Supernates
-
Loss of Gasdermin D is protective against influenza virus-induced inflammation and mortality
Authors: S Speaks, A Zani, A Solstad, A Kenney, L Zhang, AC Eddy, AO Amer, R Robinson, C Cai, J Ma, EA Hemann, A Forero, JS Yount
bioRxiv : the preprint server for biology, 2023-04-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
The dependence of particle size on cell toxicity for modern mining dust
Authors: YH Chen, D Nguyen, S Brindley, T Ma, T Xia, J Brune, JM Brown, CS Tsai
Scientific Reports, 2023-03-29;13(1):5101.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation
Authors: M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi
Scientific Reports, 2023-03-21;13(1):4656.
Species: Human
Sample Types: Cell Culture Supernates
-
Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion
Authors: Y Guo, V Kanamarlap
International Journal of Molecular Sciences, 2023-03-16;24(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
Discovering the Biological Significance and Therapeutic Potential of miR-29b-3p in Triple-Negative Breast Cancer
Authors: A Jurj, O Zanoaga, L Raduly, V Morhan, Z Papi, C Ciocan, LA Pop, I Berindan-N, C Braicu
International Journal of Molecular Sciences, 2023-03-06;24(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
TGF-beta is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells
Authors: V Klück, G Cab?u, L Mies, F Bukkems, L van Emst, R Bakker, A van Caam, HINT conso, TO Cri?an, LAB Joosten
Arthritis Research & Therapy, 2023-02-27;25(1):30.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of poly (ADP-ribose) Polymerase-1 (PARP-1) improves endothelial function in pulmonary hypertension
Authors: M Shafiq, ZR Lone, AO Abdulkaree, G Kaur, S Navya, H Singh, K Jagavelu, K Hanif
Pulmonary pharmacology & therapeutics, 2023-02-25;0(0):102200.
Species: Human
Sample Types: Cell Culture Supernates
-
Metabolic Reprogramming of Macrophages upon In Vitro Incubation with Aluminum-Based Adjuvant
Authors: R Danielsson, N Ferey, I Mile, H Eriksson
International Journal of Molecular Sciences, 2023-02-23;24(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of PARP and TRPM2 in VEGF Inhibitor-Induced Vascular Dysfunction
Authors: KB Neves, R Alves-Lope, AC Montezano, RM Touyz
Journal of the American Heart Association, 2023-02-20;0(0):e027769.
Species: Human
Sample Types: Cell Culture Supernates
-
3D Matrices for Enhanced Encapsulation and Controlled Release of Anti-Inflammatory Bioactive Compounds in Wound Healing
Authors: R Nicu, DE Ciolacu, AR Petrovici, D Rusu, M Avadanei, AC Mihaila, E Butoi, F Ciolacu
International Journal of Molecular Sciences, 2023-02-20;24(4):.
Species: Human
Sample Types: Cell Culture Supernates
-
Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA
Authors: AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger
Scientific Reports, 2023-02-16;13(1):2767.
Species: Human
Sample Types: Cell Culture Supernates
-
Opposing Effects of Interleukin-36gamma and Interleukin-38 on Trained Immunity
Authors: LU Teufel, MG Netea, FL van de Vee, CA Dinarello, LAB Joosten, RJW Arts
International Journal of Molecular Sciences, 2023-01-24;24(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype
Authors: RL Schmitz, KE Tweed, P Rehani, K Samimi, J Riendeau, I Jones, EM Maly, EC Guzman, MH Forsberg, A Shahi, CM Capitini, AJ Walsh, MC Skala
bioRxiv : the preprint server for biology, 2023-01-23;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis
Authors: M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi
PLoS ONE, 2023-01-20;18(1):e0280385.
Species: Human
Sample Types: Cell Culture Supernates
-
Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions
Authors: A Dinarello, TS Mills, IW Tengesdal, NE Powers, T Azam, CA Dinarello
Cells, 2023-01-12;12(2):.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release
Authors: G Bredeck, M Busch, A Rossi, B Stahlmecke, KW Fomba, H Herrmann, RPF Schins
Environment international, 2023-01-11;172(0):107732.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-inflammatory activities of Coleus forsteri (formerly Plectranthus forsteri) extracts on human macrophages and chemical characterization
Authors: M Nicolas, M Lasalo, S Chow, C Antheaume, K Huet, E Hnawia, GJ Guillemin, M Nour, M Matsui
Frontiers in Pharmacology, 2023-01-09;13(0):1081310.
Species: Human
Sample Types: Cell culture supernate
-
Click and bioorthogonal hyaluronic acid hydrogels as an ultra-tunable platform for the investigation of cell-material interactions
Authors: N Lagneau, P Tournier, B Halgand, F Loll, Y Maugars, J Guicheux, C Le Visage, V Delplace
Bioactive materials, 2023-01-03;24(0):438-449.
Species: Human
Sample Types: Cell Culture Supernates
-
Proteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes
Authors: JH Back, SY Kim, MB Gu, HJ Kim, KN Lee, JE Lee
Research square, 2023-01-01;0(0):.
Species: Human
Sample Types: Amniotic Fluid
-
Hepcidin as a Diagnostic Biomarker in Anaemic Lung Cancer Patients
Authors: K Wadowska, P B?asiak, A Rzechonek, I Bil-Lula, M ?liwi?ska-
Cancers, 2022-12-30;15(1):.
Species: Human
Sample Types: Serum
-
Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
Authors: TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin
Cell Reports, 2022-12-30;42(1):111905.
Species: Human
Sample Types: Cell Culture Supernates
-
Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway
Authors: K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou
International Journal of Molecular Sciences, 2022-12-23;24(1):.
Species: Human
Sample Types: Cell Culture Supernates
-
Effectiveness of Hyperbaric Oxygen Therapy in SARS-CoV-2 Pneumonia: The Primary Results of a Randomised Clinical Trial
Authors: J Siewiera, K Brodaczews, N Jermakow, A Lubas, K K?os, A Majewska, J Kot
Journal of Clinical Medicine, 2022-12-20;12(1):.
Species: Human
Sample Types: Serum
-
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium
Authors: Q Huang, M Peng, Y Gu, J Wu, Y Zhan, Z Deng, S Chen, R Yang, J Chen, J Xie
Oxidative Medicine and Cellular Longevity, 2022-12-19;2022(0):7067623.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammatory markers and auto-Abs to type I IFNs in COVID-19 convalescent plasma cohort study
Authors: F Cognasse, H Hamzeh-Cog, M Rosa, D Corseaux, B Bonneaudea, C Pierre, J Huet, CA Arthaud, MA Eyraud, A Prier, AC Duchez, T Ebermeyer, M Heesterman, E Audoux-Cai, Q Philippot, T Le Voyer, O Hequet, AM Fillet, P Chavarin, D Legrand, P Richard, F Pirenne, P Gallian, JL Casanova, S Susen, P Morel, K Lacombe, P Bastard, P Tiberghien
EBioMedicine, 2022-12-17;87(0):104414.
Species: Human
Sample Types: Cell Culture Supernates
-
Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19
Authors: AO Larsson, M Hultström, R Frithiof, M Lipcsey, MB Eriksson
International Journal of Molecular Sciences, 2022-12-10;23(24):.
Species: Human
Sample Types: Plasma
-
Phytohustil� and root extract of Althaea officinalis L. exert anti-inflammatory and anti-oxidative properties and improve the migratory capacity of endothelial cells in vitro
Authors: GA Bonaterra, J Schmitt, K Schneider, H Schwarzbac, H Aziz-Kalbh, O Kelber, J Müller, R Kinscherf
Frontiers in Pharmacology, 2022-12-08;13(0):948248.
Species: Human
Sample Types: Cell Culture Supernates
-
The Anti-Inflammatory Effects of Iberin on TNF-alpha-Stimulated Human Oral Epithelial Cells: In Vitro Research
Authors: Y Hosokawa, I Hosokawa, M Shimoyama, A Fujii, J Sato, K Kadena, K Ozaki, K Hosaka
Biomedicines, 2022-12-06;10(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study
Authors: LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts
Cytokine, 2022-12-05;162(0):156102.
Species: Human
Sample Types: Cell Culture Supernates
-
Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition
Authors: T Luong, E Cukierman
BMC Cancer, 2022-12-02;22(1):1255.
Species: Human
Sample Types: Cell Culture Supernates
-
Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study
Authors: LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues
Journal of Clinical Medicine, 2022-12-02;11(23):.
Species: Human
Sample Types: Plasma
-
A Single Chain Fragment Variant Binding Misfolded Alpha-Synuclein Exhibits Neuroprotective and Antigen-Specific Anti-Inflammatory Properties
Authors: M Fassler, C Benaim, J George
Cells, 2022-11-29;11(23):.
Species: Human
Sample Types: Whole Cells
-
Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women: impact on MAPK and NFkappaB signaling pathways
Authors: VC Capetini, BJ Quintanilh, DC de Oliveir, AH Nishioka, LA de Matos, LRP Ferreira, FM Ferreira, GR Sampaio, NMA Hassimotto, FM Lajolo, RA Fock, MM Rogero
The Journal of nutritional biochemistry, 2022-11-26;0(0):109240.
Species: Human
Sample Types: Plasma
-
EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
Authors: JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park
Arthritis Research & Therapy, 2022-11-17;24(1):254.
Species: Human
Sample Types: Serum
-
An experimental model of contusion injury in humans
Authors: MJ Barnes, D Lomiwes, DAD Parry, S Mackintosh
PLoS ONE, 2022-11-17;17(11):e0277765.
Species: Human
Sample Types: Plasma
-
Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells
Authors: CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral
Microbial pathogenesis, 2022-11-12;0(0):105881.
Species: Human
Sample Types: Cell Culture Supernates
-
On the Bioactivity of Echinacea purpurea Extracts to Modulate the Production of Inflammatory Mediators
Authors: SF Vieira, VMF Gonçalves, CP Llaguno, F Macías, ME Tiritan, RL Reis, H Ferreira, NM Neves
Oncogene, 2022-11-06;23(21):.
Species: Human
Sample Types: Cell Culture Supernates
-
High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone
Authors: L Butcher, JC Zaldua, JA Carnicero, K Hawkins, J Whitley, R Mothukuri, PA Evans, K Morris, S Pillai, JD Erusalimsk
Respiratory Research, 2022-11-05;23(1):303.
Species: Human
Sample Types: Serum
-
Enzyme-Treated Caviar Prevents UVB Irradiation-Induced Skin Photoaging
Authors: J Park, D Kim, M Lee, S Han, W Jun, HM Jung, YK Koo, GH Na, SH Han, J Han, OK Kim
Oncogene, 2022-10-30;20(11):.
Species: Human
Sample Types: Cell Culture Supernates
-
In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells
Authors: B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang
Cells, 2022-10-28;11(21):.
Species: Human
Sample Types: Cell Culture Supernates
-
Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance
Authors: H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han
BioMed Research International, 2022-10-12;2022(0):9899135.
Species: Human
Sample Types: Tissue Homogenates
-
Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS
Authors: W Dieterich, C Schuster, P Gundel, KA Scherf, D Pronin, S Geisslitz, A Börner, MF Neurath, Y Zopf
Nutrients, 2022-10-12;14(20):.
Species: Human
Sample Types: Cell Culture Supernates
-
Antimicrobial Peptides Active in In Vitro Models of Endodontic Bacterial Infections Modulate Inflammation in Human Cardiac Fibroblasts
Authors: G Mariananto, G Meogrossi, E Tollapi, A Rencinai, J Brunetti, C Marruganti, C Gaeta, A Pini, L Bracci, M Ferrari, S Grandini, C Falciani
Pharmaceutics, 2022-09-29;14(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation
Authors: P Marona, J Górka, O Kwapisz, J Jura, J Rys, RM Hoffman, K Miekus
Cell Death & Disease, 2022-09-22;13(9):814.
Species: Human, Mouse
Sample Types: Cell Culture Supernates, Plasma
-
Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases
Authors: R Lei, H Arain, M Obaid, N Sabhnani, C Mohan
Biosensors, 2022-09-14;12(9):.
Species: Human
Sample Types: Serum
-
Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts
Authors: M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker
International Journal of Molecular Sciences, 2022-09-08;23(18):.
Species: Human
Sample Types: Cell Culture Supernatants
-
Regulation of Adipose Progenitor Cell Expansion in a Novel Micro-Physiological Model of Human Adipose Tissue Mimicking Fibrotic and Pro-Inflammatory Microenvironments
Authors: V Dani, S Bruni-Favi, B Chignon-Si, A Loubat, A Doglio, C Dani
Cells, 2022-09-07;11(18):.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3
Authors: E The, DM de Graaf, Y Zhai, Q Yao, L Ao, DA Fullerton, CA Dinarello, X Meng
Proceedings of the National Academy of Sciences of the United States of America, 2022-08-29;119(36):e2202577119.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation.
Authors: Kartasheva-Ebertz D, Gaston J, Lair-Mehiri L, Mottez E, Buivan T, Massault P, Scatton O, Gaujoux S, Vaillant J, Pol S, Lagaye S
Int J Mol Sci, 2022-08-29;23(17):.
Species: Human
Sample Types: Tissue Culture Supernates
-
Pyrroloquinoline quinone (PQQ) improves pulmonary hypertension by regulating mitochondrial and metabolic functions
Authors: M Shafiq, ZR Lone, P Bharati, S Mahapatra, P Rai, N Khandelwal, AN Gaikwad, K Jagavelu, K Hanif
Pulmonary pharmacology & therapeutics, 2022-08-25;76(0):102156.
Species: Rat
Sample Types: Tissue Homogenates
-
Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity
Authors: L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo
International Journal of Molecular Sciences, 2022-08-22;23(16):.
Species: Human
Sample Types: Cell Culture Supernates
-
SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity
Authors: C Amormino, V Tedeschi, G Paldino, S Arcieri, MT Fiorillo, A Paiardini, L Tuosto, M Kunkl
Cells, 2022-08-15;11(16):.
Species: Human
Sample Types: Cell Culture Supernates
-
A Proliferation-Inducing Ligand and B-Cell Activating Factor Are Upregulated in Patients with Essential Thrombocythemia
Authors: L Bolkun, M Tynecka, T Wasiluk, J Piszcz, A Starosz, K Grubczak, M Moniuszko, A Eljaszewic
Journal of Clinical Medicine, 2022-08-09;11(16):.
Species: Human
Sample Types: Serum
-
Hydrogen Sulfide and Substance P Levels in Patients with Escherichia coli and Klebsiella pneumoniae Bacteraemia
Authors: S Manandhar, A Scott-Thom, M Harrington, P Sinha, A Pilbrow, AM Richards, V Cameron, M Bhatia, ST Chambers
International Journal of Molecular Sciences, 2022-08-03;23(15):.
Species: Human
Sample Types: Plasma
-
Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells
Authors: JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer
Scientific Reports, 2022-08-01;12(1):13202.
Species: Human
Sample Types: Cell Culture Supernates
-
Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells
Authors: Y Xu, M Twarog, N Li, A Banks, J Schustak, Y Bao, Q Huang, QG Medley
PLoS ONE, 2022-07-28;17(7):e0271656.
Species: Human
Sample Types: Cell Culture Supernates
-
Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis
Authors: S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek
Journal of ovarian research, 2022-07-26;15(1):87.
Species: Human
Sample Types: Cell Culture Supernates
-
Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems
Authors: LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt
Scientific Reports, 2022-07-20;12(1):12448.
Species: Human
Sample Types: Cell Culture Supernates
-
Nasal-spraying Bacillus spores as an effective symptomatic treatment for children with acute respiratory syncytial virus infection
Authors: DM Tran, TT Tran, TTB Phung, HT Bui, PTT Nguyen, TT Vu, NTP Ngo, MT Nguyen, AH Nguyen, ATV Nguyen
Scientific Reports, 2022-07-20;12(1):12402.
Species: Human
Sample Types: Nasal Lavage Fluid
-
Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1
Authors: H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd
Mucosal Immunology, 2022-07-15;0(0):.
Species: Human
Sample Types: Cell culture supernate
-
Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression
Authors: M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta
Cancers, 2022-07-13;14(14):.
Species: Human
Sample Types: Cell Culture Supernates
-
Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling
Authors: J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li
International journal of biological sciences, 2022-07-11;18(11):4545-4559.
Species: Human
Sample Types: Cell Culture Supernates
-
Commercially Available Flavonols Are Better SARS-CoV-2 Inhibitors than Isoflavone and Flavones
Authors: OA Chaves, N Fintelman-, X Wang, CQ Sacramento, JR Temerozo, AC Ferreira, M Mattos, F Pereira-Du, PT Bozza, HC Castro-Far, JJ Russo, J Ju, TML Souza
Viruses, 2022-06-30;14(7):.
Species: Human
Sample Types: Cell Culture Supernates
-
From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-kappaB inhibitors
Authors: RA Wagdy, PJ Chen, MM Hamed, SS Darwish, SH Chen, AH Abadi, M Abdel-Hali, TL Hwang, M Engel
Bioorganic chemistry, 2022-06-18;127(0):105977.
Species: Human
Sample Types: Cell Culture Supernates
-
Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation
Authors: S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu
Oncogene, 2022-06-09;2022(0):1671438.
Species: Human
Sample Types: Cell Culture Supernates
-
Celastrol alleviates high-fat diet-induced obesity via enhanced muscle glucose utilization and mitochondrial oxidative metabolism-mediated upregulation of pyruvate dehydrogenase complex
Authors: MHA Bakar, NSN Shahril, MSFM Khalid, S Mohammad, KA Shariff, T Karunakara, RM Salleh, MN Rosdi
Oncogene, 2022-06-06;449(0):116099.
Species: Mouse
Sample Types: Serum
-
Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus
Authors: JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich
Cellular Signalling, 2022-05-21;96(0):110360.
Species: Human
Sample Types: Plasma
-
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease
Authors: Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng, S Chen, X Wu, Y Lv, Z Zeng, J Xie
Respiratory Research, 2022-05-12;23(1):120.
Species: Human
Sample Types: Cell Culture Supernates
-
Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid
Authors: KN Lee, KH Park, YM Kim, I Cho, TE Kim
PLoS ONE, 2022-05-10;17(5):e0268291.
Species: Human
Sample Types: Amniotic Fluid
-
Green and Roasted Coffee Extracts Inhibit Interferon-beta Release in LPS-Stimulated Human Macrophages
Authors: V Artusa, C Ciaramelli, A D'Aloia, FA Facchini, N Gotri, A Bruno, B Costa, A Palmioli, C Airoldi, F Peri
Frontiers in Pharmacology, 2022-05-05;13(0):806010.
Species: Human
Sample Types: Cell Culture Supernates
-
IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
Cells, 2022-04-30;11(9):.
Species: Human
Sample Types: Cell Culture Supernates
-
In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release
Authors: M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue
International Journal of Molecular Sciences, 2022-04-06;23(7):.
Species: Human
Sample Types: Cell Culture Supernates
-
Discovery of a novel GRPR antagonist for protection against cisplatin-induced acute kidney injury
Authors: MJ Yu, C Li, SS Deng, XM Meng, RS Yao
Bioorganic chemistry, 2022-04-06;124(0):105794.
Species: Human
Sample Types: Cell Culture Supernates
-
Urine Hydrogen Peroxide Levels and Their Relation to Outcome in Patients with Sepsis, Septic Shock, and Major Burn Injury
Authors: M Lipcsey, M Bergquist, R Sirén, A Larsson, F Huss, J Pravda, M Furebring, J Sjölin, H Janols
Biomedicines, 2022-04-05;10(4):.
Species: Human
Sample Types: Plasma
-
Immune Modulating Brevetoxins: Monocyte Cytotoxicity, Apoptosis, and Activation of M1/M2 Response Elements Is Dependent on Reactive Groups
Authors: JR McCall, KT Sausman, DM Keeler, AP Brown, SL Turrise
Marine Drugs, 2022-03-29;20(4):.
Species: Human
Sample Types: Cell Culture Supernates
-
Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium
Authors: P Esteves, B Allard, A Celle, I Dupin, E Maurat, O Ousova, M Thumerel, JW Dupuy, T Leste-Lass, R Marthan, PO Girodet, T Trian, P Berger
Cell Reports, 2022-03-29;38(13):110571.
Species: Human
Sample Types: Cell Culture Supernates
-
Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts
Authors: S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne
Pharmaceutics, 2022-03-28;14(4):.
Species: Human
Sample Types: Cell Culture Supernates
-
Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses
Authors: H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ET Davis, SP Young, C Mauro, SW Jones
International Journal of Molecular Sciences, 2022-03-17;23(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site
Authors: G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown
Scientific Reports, 2022-03-07;12(1):3990.
Species: Human
Sample Types: Blister Fluid
-
Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women
Authors: A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith
Cells, 2022-03-01;11(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model
Authors: E Singh, RAM Osmani, R Banerjee, AS Abu Lila, A Moin, K Almansour, HH Arab, HF Alotaibi, ES Khafagy
Pharmaceutics, 2022-02-26;14(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Depolymerization of fucoidan with endo-fucoidanase changes bioactivity in processes relevant for bone regeneration
Authors: J Ohmes, MD Mikkelsen, TT Nguyen, VHN Tran, S Meier, MS Nielsen, M Ding, A Seekamp, AS Meyer, S Fuchs
Carbohydrate polymers, 2022-02-24;286(0):119286.
Species: Human
Sample Types: Cell Culture Supernates
-
E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing
Authors: AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl
Cells, 2022-02-23;11(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Comparative Analysis of Circulating Levels of SARS-CoV-2 Antibodies and Inflammatory Mediators in Healthcare Workers and COVID-19 Patients
Authors: LM de-Oliveir, VE Fiestas So, M de Lourdes, C Fernandes-, PH Damasco, MAMT de Siqueir, HG Dias, A Pauvolid-C, PV Damasco, EL de Azeredo
Viruses, 2022-02-23;14(3):.
Species: Human
Sample Types: Plasma
-
Plasmon-enhanced Quantitative Lateral Flow Assay for Femtomolar Detection of SARS-CoV-2 Antibodies and Antigens
Authors: R Gupta, P Gupta, Z Wang, A Seth, J Morrissey, I George, S Gandra, G Storch, B Parikh, G Genin, S Singamanen
Research square, 2022-02-21;0(0):.
Species: Human
Sample Types: Recombinant Proteins
-
Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS
Authors: J Zinngrebe, B Moepps, T Monecke, P Gierschik, F Schlichtig, TFE Barth, G Strau beta, E Boldrin, C Posovszky, A Schulz, O Beringer, E Rieser, EM Jacobsen, MR Lorenz, K Schwarz, U Pannicke, H Walczak, D Niessing, C Schuetz, P Fischer-Po, KM Debatin
Embo Molecular Medicine, 2022-02-16;0(0):e14901.
Species: Human
Sample Types: Cell Culture Supernates
-
Weight Loss and Short-Chain Fatty Acids Reduce Systemic Inflammation in Monocytes and Adipose Tissue Macrophages from Obese Subjects
Authors: S Eslick, EJ Williams, BS Berthon, T Wright, C Karihaloo, M Gately, LG Wood
Nutrients, 2022-02-11;14(4):.
Species: Human
Sample Types: Cell Culture Supernates
-
The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model
Authors: B van der Lu, MCP Vos, M Grootte Br, N Ijssennagg, F Vrieling, J Meijerink, WT Steegenga
Heliyon, 2022-02-02;8(2):e08883.
Species: Human
Sample Types: Cell Culture Supernates
-
Association of Genetic Variants in IL6 Gene (rs1800795) with the Concentration of Inflammatory Markers (IL-6, hs-CRP) and Superoxide Dismutase in the Blood of Patients with Acute Pancreatitis-Preliminary Findings
Authors: M O?dakowska, M ?ciskalska, M Kepinska, G Marek, H Milnerowic
Genes, 2022-02-01;13(2):.
Species: Human
Sample Types: Plasma
-
Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement
Authors: C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert
International Journal of Molecular Sciences, 2022-01-28;23(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
A New Perspective for Bone Tissue Engineering: Human Mesenchymal Stromal Cells Well-Survive Cryopreservation on beta-TCP Scaffold and Show Increased Ability for Osteogenic Differentiation
Authors: L Leppik, A Gempp, Z Kuçi, S Kuçi, P Bader, H Bönig, I Marzi, D Henrich
International Journal of Molecular Sciences, 2022-01-26;23(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory alpha7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm
Authors: YK Lin, CT Yeh, KT Kuo, IH Fong, VK Yadav, NG Kounis, P Hu, MY Hung
Oxidative Medicine and Cellular Longevity, 2022-01-19;2022(0):9964689.
Species: Human
Sample Types: Cell Culture Supernates
-
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
Authors: Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie
Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269.
Species: Human
Sample Types: Cell Culture Supernates
-
Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis
Authors: R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler
Biomedicines, 2022-01-07;10(1):.
Species: Human
Sample Types: Cell Culture Supernates
-
Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
Authors: P Brandi, L Conejero, FJ Cueto, S Martínez-C, G Dunphy, MJ Gómez, C Relaño, P Saz-Leal, M Enamorado, A Quintas, A Dopazo, J Amores-Ini, C Del Fresno, E Nistal-Vil, C Ardavín, A Nieto, M Casanovas, JL Subiza, D Sancho
Cell Reports, 2022-01-04;38(1):110184.
Species: Human
Sample Types: Cell Culture Supernates
-
Skin Substitute Preparation Method Induces Immunomodulatory Changes in Co-Incubated Cells through Collagen Modification
Authors: J Holl, C Pawlukiani, J Corton Rui, D Groth, K Grubczak, HR Hady, J Dadan, J Reszec, S Czaban, C Kowalewski, M Moniuszko, A Eljaszewic
Pharmaceutics, 2021-12-15;13(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression
Authors: J Jhun, HS Na, KH Cho, J Kim, YM Moon, SY Lee, JS Lee, AR Lee, SJ Kim, ML Cho, SH Park
PLoS ONE, 2021-12-02;16(12):e0259130.
Species: Human
Sample Types: Cell Culture Supernates
-
Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures
Authors: JW Kennedy, PM Tsimbouri, P Campsie, S Sood, PG Childs, S Reid, PS Young, DRM Meek, CS Goodyear, MJ Dalby
Scientific Reports, 2021-11-23;11(1):22741.
Species: Human
Sample Types: Cell Culture Supernates
-
Proteomic identification of novel plasma biomarkers associated with spontaneous preterm birth in women with preterm labor without infection/inflammation
Authors: JE Lee, KH Park, HJ Kim, YM Kim, JW Choi, S Shin, KN Lee
PLoS ONE, 2021-10-28;16(10):e0259265.
Species: Human
Sample Types: Amniotic Fluid
-
Bone Marrow Microenvironment in Light-Chain Amyloidosis: In Vitro Expansion and Characterization of Mesenchymal Stromal Cells
Authors: C Valsecchi, S Croce, A Maltese, L Montagna, E Lenta, A Nevone, M Girelli, P Milani, T Bosoni, M Massa, C Abbà, R Campanelli, J Ripepi, A De Silvest, A Carolei, G Palladini, M Zecca, M Nuvolone, MA Avanzini
Biomedicines, 2021-10-22;9(11):.
Species: Human
Sample Types: Cell Culture Supernates
-
The effects of the dietary compound L-sulforaphane against respiratory pathogens
Authors: N Mazarakis, RA Higgins, J Anderson, ZQ Toh, RB Luwor, KJ Snibson, TC Karagianni, LAH Do, PV Licciardi
International journal of antimicrobial agents, 2021-10-22;0(0):106460.
Species: Human
Sample Types: Cell Culture Supernates
-
Biomarkers of Pulmonary Hypertension Are Altered in Children With Down Syndrome and Pulmonary Hypertension
Authors: M Griffiths, J Yang, D Vaidya, M Nies, S Brandal, DD Ivy, F Hickey, K Wolter-War, ED Austin, M Mullen, MW Pauciulo, KA Lutz, EB Rosenzweig, R Hirsch, D Yung, WC Nichols, AD Everett
The Journal of pediatrics, 2021-10-21;0(0):.
Species: Human
Sample Types: Plasma
-
A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers
Authors: SC Lean, RL Jones, SA Roberts, AEP Heazell
BMC pregnancy and childbirth, 2021-10-20;21(1):706.
Species: Human
Sample Types: Serum
-
Gomisin M2 alleviates psoriasis?like skin inflammation by inhibiting inflammatory signaling pathways
Authors: N Kim, S Lee, J Kang, TK Kwon, D Khang, SH Kim
Molecular Medicine Reports, 2021-10-19;24(6):.
Species: Human
Sample Types: Serum
-
Persistent Effect of Advanced Glycated Albumin Driving Inflammation and Disturbances in Cholesterol Efflux in Macrophages
Authors: CA Minanni, A Machado-Li, RT Iborra, LS Okuda, R de Souza P, MFM Santana, ALA Lira, ER Nakandakar, MLC Côrrea-Gia, M Passarelli
Nutrients, 2021-10-17;13(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen
Authors: SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy
International Journal of Molecular Sciences, 2021-10-15;22(20):.
Species: Human
Sample Types: Cell Culture Supernates
-
Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes
Authors: N Yao, T Tretter, P Kvacskay, W Merkt, N Blank, HM Lorenz, LO Tykocinski
Biomedicines, 2021-10-08;9(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics
Authors: B Texler, A Zollner, V Reinstadle, SJ Reider, S Macheiner, B Jelusic, A Pfister, C Watschinge, N Przysiecki, H Tilg, H Oberacher, AR Moschen
Cellular and Molecular Gastroenterology and Hepatology, 2021-10-06;0(0):.
Species: Human
Sample Types: Cell culture supernate
-
IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming
Authors: N Niu, J Yao, RC Bast, AK Sood, J Liu
Oncogenesis, 2021-09-29;10(9):65.
Species: Human
Sample Types: Cell Culture Supernates
-
The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury
Authors: M Lale Ataei, M Karimipour, P Shahabi, R Pashaei-As, E Ebrahimie, M Pashaiasl
Cells, 2021-09-28;10(10):.
Species: Rat
Sample Types: Cell Culture Superantes
-
The influence of the gut microbiome on BCG-induced trained immunity
Authors: M Stražar, VP Mourits, VACM Koeken, LCJ de Bree, SJCFM Moorlag, LAB Joosten, R van Crevel, H Vlamakis, MG Netea, RJ Xavier
Genome Biology, 2021-09-22;22(1):275.
Species: Human
Sample Types: Cell Culture Supernates
-
Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021-09-21;36(12):109726.
Species: Human
Sample Types: Cell Culture Supernates
-
Multi-level inhibition of coronavirus replication by chemical ER stress
Authors: MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht
Nature Communications, 2021-09-20;12(1):5536.
Species: Human
Sample Types: Cell Culture Supernates
-
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis
Authors: S Schlichtne, NH Meyer, IM Yasinska, N Aliu, SM Berger, BF Gibbs, E Fasler-Kan, VV Sumbayev
International immunopharmacology, 2021-09-17;100(0):108155.
Species: Human
Sample Types: Cell Culture Supernates
-
Different Profiles of Cytokines, Chemokines and Coagulation Mediators Associated with Severity in Brazilian Patients Infected with Dengue Virus
Authors: VE Fiestas So, NR da Costa F, CF Dos Santos, G Corrêa, MDC Cipitelli, M Dornelas R, LJ de Souza, PV Damasco, RV da Cunha, FB Dos Santos, LM de Oliveir, EL de Azeredo
Viruses, 2021-09-08;13(9):.
Species: Human
Sample Types: Plasma
-
Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells
Authors: A Laustsen, RM van der Sl, A Gris-Olive, SS Hernández, E Cemalovic, HQ Tang, LH Pedersen, N Uldbjerg, MR Jakobsen, RO Bak
Elife, 2021-09-02;10(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass
Authors: M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié
Journal of leukocyte biology, 2021-08-23;0(0):.
Species: Human
Sample Types: Plasma
-
In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei
Authors: D Reddi, L Durant, D Bernardo, A Noble, NR English, P Hendy, GC Clark, JL Prior, ED Williamson, SC Knight
Vaccines, 2021-08-22;9(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection
Authors: G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi
PloS Biology, 2021-08-19;19(8):e3001387.
Species: Human
Sample Types: Plasma
-
Daily Vegetables Intake and Response to COPD Rehabilitation. The Role of Oxidative Stress, Inflammation and DNA Damage
Authors: S Ilari, L Vitiello, P Russo, S Proietti, M Mili?, C Muscoli, V Cardaci, C Tomino, G Bonassi, S Bonassi
Nutrients, 2021-08-14;13(8):.
Species: Human
Sample Types: Plasma
-
New Insights on Old Biomarkers Involved in Tumor Microenvironment Changes and Their Diagnostic Relevance in Non-Small Cell Lung Carcinoma
Authors: K Wadowska, P B?asiak, A Rzechonek, I Bil-Lula, M ?liwi?ska-
Biomolecules, 2021-08-13;11(8):.
Species: Human
Sample Types: Serum
-
Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction
Authors: Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson
Cell Death & Disease, 2021-08-06;12(8):775.
Species: Human
Sample Types: Cell Culture Supernates
-
Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes
Authors: E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz
Biology, 2021-08-04;10(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of remifentanil on human C20 microglial pro-inflammatory activation
Authors: N Cappoli, P Aceto, E Tabolacci, D Mezzogori, L Sollazzi, P Navarra, C Dello Russ
European review for medical and pharmacological sciences, 2021-08-01;25(16):5268-5274.
Species: Human
Sample Types: Cell Culture Supernates
-
Omega-3 Polyunsaturated Fatty Acid: A Pharmaco-Nutraceutical Approach to Improve the Responsiveness to Ursodeoxycholic Acid
Authors: A Thérien, A Cie?lak, M Verreault, M Perreault, J Trottier, S Gobeil, MC Vohl, O Barbier
Nutrients, 2021-07-29;13(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit
Authors: T Katopodi, S Petanidis, K Domvri, P Zarogoulid, D Anestakis, C Charalampi, D Tsavlis, C Bai, H Huang, L Freitag, W Hohenforst, D Matthaios, K Porpodis
Scientific Reports, 2021-07-29;11(1):15455.
Species: Human
Sample Types: Cell Culture Supernates
-
Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy
Authors: JY Park, JS Hyun, JG Jee, SJ Park, D Khang
International Journal of Nanomedicine, 2021-07-22;16(0):4943-4957.
Species: Human
Sample Types: Cell Culture Supernates
-
Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells
Authors: B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero
Polymers, 2021-07-18;13(14):.
Species: Human
Sample Types: Cell Culture Supernates
-
Characterization of low-density granulocytes in COVID-19
Authors: LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin
PloS Pathogens, 2021-07-06;17(7):e1009721.
Species: Human
Sample Types: Serum
-
Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis
Authors: JK Park, S Shon, HJ Yoo, DH Suh, D Bae, J Shin, JH Jun, N Ha, H Song, YI Choi, T Pap, YW Song
Arthritis Research & Therapy, 2021-07-05;23(1):177.
Species: Human
Sample Types: Cell Culture Supernates
-
Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled phase 2 trial
Authors: V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte, S Karmali, DW Birch, KK Samarasing, J Walter, KL Madsen
Nature Medicine, 2021-07-05;27(7):1272-1279.
Species: Human
Sample Types: Serum
-
Novel immunomodulatory properties of low dose cytarabine entrapped in a mannosylated cationic liposome
Authors: AL Martel, NL Fraleigh, E Picard, JD Lewicky, G Pawelec, H Lee, GW Ma, L Mousavifar, R Roy, HT Le
International journal of pharmaceutics, 2021-07-01;0(0):120849.
Species: Human
Sample Types: Cell Culture Supernates
-
Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
Authors: KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess
Cells, 2021-06-29;10(7):.
Species: Human
Sample Types: Cell Culture Supernates
-
An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles
Authors: M Busch, AAM Kämpfer, RPF Schins
Chemosphere, 2021-06-28;284(0):131345.
Species: Human
Sample Types: Cell Culture Supernates
-
DHX15 is required to control RNA virus-induced intestinal inflammation
Authors: J Xing, X Zhou, M Fang, E Zhang, LJ Minze, Z Zhang
Cell Reports, 2021-06-22;35(12):109205.
Species: Human
Sample Types: Cell Culture Supernates
-
The dynamics of human bone marrow adipose tissue in response to feeding and fasting
Authors: PK Fazeli, MA Bredella, OG Pachon-Peñ, W Zhao, X Zhang, AT Faje, M Resulaj, SP Polineni, TM Holmes, H Lee, EK O'Donnell, OA MacDougald, MC Horowitz, CJ Rosen, A Klibanski
JCI Insight, 2021-06-22;0(0):.
Species: Human
Sample Types: Serum
-
Predictors of Early-Recurrence Atrial Fibrillation after Catheter Ablation in Women and Men with Abnormal Body Weight
Authors: J Budzianows, J Hiczkiewic, K ?ojewska, E Kawka, R Rutkowski, K Korybalska
Journal of Clinical Medicine, 2021-06-18;10(12):.
Species: Human
Sample Types: Serum
-
Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection
Authors: V Mocanu, H Park, J Dang, N Hotte, A Thiesen, M Laffin, H Wang, D Birch, K Madsen
Nutrients, 2021-06-17;13(6):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
Authors: YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang
Arthritis Research & Therapy, 2021-06-16;23(1):171.
Species: Human
Sample Types: Cell Culture Supernates
-
Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance
Authors: CM Yamazaki, A Yamaguchi, Y Anami, W Xiong, Y Otani, J Lee, NT Ueno, N Zhang, Z An, K Tsuchikama
Nature Communications, 2021-06-10;12(1):3528.
Species: Human
Sample Types: Cell Culture Supernates
-
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Authors: LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller
Nature Communications, 2021-06-10;12(1):3543.
Species: Human
Sample Types: Exosomes
-
Bacterial genotoxins induce T�cell senescence
Authors: SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard
Cell Reports, 2021-06-08;35(10):109220.
Species: Human
Sample Types: Cell Culture Supernates
-
Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritis
Authors: CY Wu, WL Fan, YM Chiu, HY Yang, WI Lee, JL Huang
Scientific Reports, 2021-06-07;11(1):11903.
Species: Human
Sample Types: Plasma
-
Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein
Authors: E Jover, L Matilla, M Garaikoetx, A Fernández-, P Muntendam, F Jaisser, P Rossignol, N López-Andr
Biomedicines, 2021-06-03;9(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response
Authors: M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich
PloS Biology, 2021-06-01;19(6):e3001247.
Species: Human
Sample Types: Cell Culture Supernates
-
Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case-control study
Authors: MCC Volkweis, GW Neculqueo, RDS Freitas, APA Dagnino, GG Fritscher, TQ Irigaray, MM Campos
Scientific Reports, 2021-05-26;11(1):11083.
Species: Human
Sample Types: Saliva
-
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
Autophagy, 2021-05-24;0(0):1-20.
Species: Rat
Sample Types: Serum
-
Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis
Authors: Y Li, C Bax, J Patel, T Vazquez, A Ravishanka, MM Bashir, M Grinnell, D Diaz, VP Werth
Theranostics, 2021-05-21;11(15):7144-7158.
Species: Human
Sample Types: Cell Culture Supernates
-
Decreased microRNA-155 in Behcet's disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production
Authors: L Liang, Q Zhou, L Feng
Arthritis Research & Therapy, 2021-05-06;23(1):135.
Species: Human
Sample Types: Cell Culture Supernates
-
Plasma markers in pulmonary hypertension subgroups correlate with patient survival
Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
Respiratory Research, 2021-05-04;22(1):137.
Species: Human
Sample Types: Plasma
-
Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection
Authors: N Bozorgmehr, S Mashhouri, E Perez Rose, L Xu, S Shahbaz, W Sligl, M Osman, DJ Kutsogiann, E MacIntyre, CR O'Neil, S Elahi
MBio, 2021-05-04;12(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Peripheral Nerve-Derived Stem Cell Spheroids Induce Functional Recovery and Repair after Spinal Cord Injury in Rodents
Authors: HL Lee, CE Yeum, H Lee, J Oh, JT Kim, WJ Lee, Y Ha, YI Yang, KN Kim
International Journal of Molecular Sciences, 2021-04-16;22(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
Authors: R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare
Cell Reports, 2021-03-23;34(12):108891.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophil extracellular trap clearance by synovial macrophages in gout
Authors: JH Jeong, SJ Choi, SM Ahn, JS Oh, YG Kim, CK Lee, B Yoo, S Hong
Arthritis Research & Therapy, 2021-03-19;23(1):88.
Species: Human
Sample Types: Cell Culture Supernates
-
Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response
Authors: MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad
Cell Death & Disease, 2021-03-04;12(3):241.
Species: Human
Sample Types: Cell Culture Supernates
-
Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension
Authors: AYY Tam, AL Horwell, SL Trinder, K Khan, S Xu, V Ong, CP Denton, JT Norman, AM Holmes, G Bou-Ghario, DJ Abraham
The international journal of biochemistry & cell biology, 2021-03-01;134(0):105961.
Species: Human
Sample Types: Cell Culture Supernates
-
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
Nature Communications, 2021-02-22;12(1):1209.
Species: Human
Sample Types: Cell Culture Supernates
-
Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma
Authors: JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman
Scientific Reports, 2021-02-15;11(1):3802.
Species: Human
Sample Types: Cell Culture Supernates
-
Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
Authors: P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski
Arthritis Research & Therapy, 2021-02-15;23(1):56.
Species: Human
Sample Types: Cell Culture Supernates
-
Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae
Authors: AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth
PLoS ONE, 2021-02-11;16(2):e0246803.
Species: Human
Sample Types: Cell Culture Supernates
-
PHAIR: a biosensor for pH measurement in air-liquid interface cell culture
Authors: M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota
Scientific Reports, 2021-02-10;11(1):3477.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes
Authors: P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai
PLoS ONE, 2021-02-03;16(2):e0246381.
Species: Human
Sample Types: Cell Culture Supernates
-
Downregulation of miR-126-3p expression contributes to increased inflammatory response in placental trophoblasts in preeclampsia
Authors: X Chu, Y Gu, W Sheng, J Sun, JA Morgan, DF Lewis, DB Cooper, CE McCathran, Y Wang
Journal of reproductive immunology, 2021-02-01;144(0):103281.
Species: Human
Sample Types: Cell Culture Supernates
-
Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway
Authors: MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito
PLoS ONE, 2021-02-01;16(2):e0246050.
Species: Human
Sample Types: Cell Culture Supernates
-
The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells
Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
BioMed Research International, 2021-01-28;2021(0):8826586.
Species: Human
Sample Types: Cell Culture Supernates
-
Study of fucoidans as natural biomolecules for therapeutical applications in osteoarthritis
Authors: C Vaamonde-G, N Flórez-Fer, MD Torres, MJ Lamas-Vázq, FJ Blanco, H Domínguez, R Meijide-Fa
Carbohydrate polymers, 2021-01-26;258(0):117692.
Species: Human
Sample Types: Cell Culture Supernates
-
Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
Authors: SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai
Scientific Reports, 2021-01-14;11(1):1462.
Species: Human
Sample Types: Cell Culture Supernates
-
New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response
Authors: RP Madeira, LM Dal'Mas Ro, P de Cássia, C Mady, BM Ianni, AC Torrecilha
Journal of Immunology Research, 2021-01-11;2021(0):6650670.
Species: Human
Sample Types: Cell Culture Supernates
-
Corneal Keratocyte Density and Corneal Nerves Are Reduced in Patients With Severe Obesity and Improve After Bariatric Surgery
Authors: Z Iqbal, A Kalteniece, M Ferdousi, S Adam, L D'Onofrio, JH Ho, AP Rao, S Dhage, S Azmi, Y Liu, R Donn, RA Malik, H Soran
Investigative Ophthalmology & Visual Science, 2021-01-04;62(1):20.
Species: Human
Sample Types: Serum
-
Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro
Authors: R Björkenhei, E Jämsen, E Eriksson, P Uppstu, L Aalto-Setä, L Hupa, KK Eklund, M Ainola, NC Lindfors, J Pajarinen
European cells & materials, 2021-01-03;41(0):15-30.
Species: Human
Sample Types: Cell Culture Supernates
-
Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
Authors: LJ Williams, SG Tristram, GR Zosky
International Journal of Environmental Research and Public Health, 2020-12-28;18(1):.
Species: Human
Sample Types: Cell Culture Supernates
-
A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia
Authors: P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier
Cancer Medicine, 2020-12-25;0(0):.
Species: Human
Sample Types: Serum
-
SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
medRxiv : the preprint server for health sciences, 2020-12-09;0(0):.
Species: Human
Sample Types: Fecal Supernates
-
Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist
Authors: H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier
Frontiers in Pharmacology, 2020-12-08;11(0):598702.
Species: Human
Sample Types: Cell Culture Supernates
-
Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion
Authors: M Estermann, YL Huang, D Septiadi, D Ritz, CY Liang, F Jacob, B Drasler, A Petri-Fink, V Heinzelman, B Rothen-Rut
PLoS ONE, 2020-12-03;15(12):e0241500.
Species: Human
Sample Types: Abdominal Fluid
-
Co-Adsorption of Synthetic Mincle Agonists and Antigen to Silica Nanoparticles for Enhanced Vaccine Activity: A Formulation Approach to Co-Delivery
Authors: WM Abdelwahab, A Riffey, C Buhl, C Johnson, K Ryter, JT Evans, DJ Burkhart
Int J Pharm, 2020-11-27;0(0):120119.
Species: Human
Sample Types: Cell Culture Supernates
-
Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes
Authors: M De, A Bhushan, S Chinnaswam
J Leukoc Biol, 2020-11-17;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells
Authors: CA Ciocan-Car, A Jurj, O Zanoaga, R Cojocneanu, LA Pop, A Moldovan, C Moldovan, AA Zimta, L Raduly, C Pop-Bica, M Buse, L Budisan, P Virag, A Irimie, SMG Diaz, I Berindan-N, C Braicu
J Exp Clin Cancer Res, 2020-11-13;39(1):241.
Species: Human
Sample Types: Cell Culture Supernates
-
Identifying potential biomarkers related to pre-term delivery by proteomic analysis of amniotic fluid
Authors: S Hong, JE Lee, YM Kim, Y Park, JW Choi, KH Park
Sci Rep, 2020-11-12;10(1):19648.
Species: Human
Sample Types: Amniotic Fluid
-
ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
FEBS Open Bio, 2020-11-06;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint
Authors: A Floudas, N Neto, V Marzaioli, K Murray, B Moran, MG Monaghan, C Low, RH Mullan, N Rao, V Krishna, S Nagpal, DJ Veale, U Fearon
JCI Insight, 2020-11-05;5(21):.
Species: Human
Sample Types: Cell Culture Supernates
-
Rescuing key native traits in cultured dermal papilla cells for human hair regeneration
Authors: CM Abreu, MT Cerqueira, RP Pirraco, L Gasperini, RL Reis, AP Marques
Journal of advanced research, 2020-11-04;30(0):103-112.
Species: Human
Sample Types: Cell Culture Supernates
-
CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features
Authors: M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi
PLoS ONE, 2020-11-02;15(11):e0241719.
Species: Human
Sample Types: Serum
-
Boosting NAD Level Suppresses Inflammatory Activation of PBMC in Heart Failure
Authors: B Zhou, DD Wang, Y Qiu, S Airhart, Y Liu, A Stempien-O, KD O'Brien, R Tian
J. Clin. Invest., 2020-11-02;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1
Authors: P Pe?an, S Hambalkó, VT Ha, CT Nagy, C Pelyhe, D Lainš?ek, B Kenyeres, GB Brenner, A Görbe, Á Kittel, M Barteková, P Ferdinandy, M Man?ek-Keb, Z Giricz
Int J Mol Sci, 2020-10-16;21(20):.
Species: Human
Sample Types: Cell Culture Supernates
-
Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy
Authors: M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg
Mol Ther, 2020-10-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
An observational study of innate immune responses in patients with acute appendicitis
Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
Sci Rep, 2020-10-15;10(1):17352.
Species: Human
Sample Types: Cell Culture Supernates
-
The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis
Authors: MA Rahat, M Safieh, E Simanovich, E Pasand, T Gazitt, A Haddad, M Elias, D Zisman
Arthritis Res Ther, 2020-10-14;22(1):240.
Species: Human
Sample Types: Serum
-
Interleukin-26 activates macrophages and facilitates killing of Mycobacterium tuberculosis
Authors: HC Hawerkamp, L van Geelen, J Korte, J Di Domizio, M Swidergall, AA Momin, FJ Guzmán-Veg, ST Arold, J Ernst, M Gilliet, R Kalscheuer, B Homey, S Meller
Sci Rep, 2020-10-14;10(1):17178.
Species: Human
Sample Types: Cell Culture Supernates
-
Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
Cell Rep, 2020-10-13;33(2):108247.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-&alpha
Authors: F Al-Rashed, Z Ahmad, R Thomas, M Melhem, AJ Snider, LM Obeid, F Al-Mulla, YA Hannun, R Ahmad
Sci Rep, 2020-10-08;10(1):16802.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency
Authors: M Werner-Kle, A Grujovic, C Irlbeck, M Obradovi?, M Hoffmann, H Koerkel-Qu, X Lu, S Treitschke, C Köstler, C Botteron, K Weidele, C Werno, B Polzer, S Kirsch, M Gužvi?, J Warfsmann, K Honarnejad, Z Czyz, G Feliciello, I Blochberge, S Grunewald, E Schneider, G Haunschild, N Patwary, S Guetter, S Huber, B Rack, N Harbeck, S Buchholz, P Rümmele, N Heine, S Rose-John, CA Klein
Nat Commun, 2020-10-05;11(1):4977.
Species: Human
Sample Types: Cell Culture Supernates
-
Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion
Authors: YH Kim, MS Kwak, B Lee, JM Shin, S Aum, IH Park, MG Lee, JS Shin
Autophagy, 2020-10-05;0(0):1-18.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury
Authors: CG de Oliveir, MVM de Andrade, LR Guedes, HC Rocha, RG Guimarães, FAC Carvalho, EG Vilela
Mediators Inflamm, 2020-09-25;2020(0):2867241.
Species: Human
Sample Types: Serum
-
Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells
Authors: PT Tien, HJ Lin, YY Tsai, YP Lim, CS Chen, CY Chang, CJ Lin, JJ Chen, SM Wu, YJ Huang, L Wan
Scientific Reports, 2020-09-24;10(1):15702.
Species: Human
Sample Types: Whole Cells
-
In Vitro Characterization of Gut Microbiota-Derived Commensal Strains: Selection of Parabacteroides distasonis Strains Alleviating TNBS-Induced Colitis in Mice
Authors: B Cuffaro, ALW Assohoun, D Boutillier, L Súkeníková, J Desramaut, S Boudebbouz, S Salomé-Des, J Hrdý, AJ Waligora-D, E Maguin, C Grangette
Cells, 2020-09-16;9(9):.
Species: Human
Sample Types: Cell Culture Supernates
-
Enrichment of apolipoprotein A-IV and apolipoprotein D in the HDL proteome is associated with HDL functions in diabetic kidney disease without dialysis
Authors: MFM Santana, ALA Lira, RS Pinto, CA Minanni, ARM Silva, MIBAC Sawada, ER Nakandakar, MLC Correa-Gia, MS Queiroz, GE Ronsein, M Passarelli
Lipids Health Dis, 2020-09-14;19(1):205.
Species: Human
Sample Types: Cell Culture Supernates
-
Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding
Authors: A Iannucci, V Caneparo, S Raviola, I Debernardi, D Colangelo, R Miggiano, G Griffante, S Landolfo, M Gariglio, M De Andrea
PLoS Pathog., 2020-09-09;16(9):e1008811.
Species: Human
Sample Types: Cell Culture Supernates
-
The NRF2 stimulating agent, tin protoporphyrin, activates protective cytokine pathways in healthy human subjects and in patients with chronic kidney disease
Authors: RA Zager, ACM Johnson
Physiol Rep, 2020-09-01;8(18):e14566.
Species: Human
Sample Types: Plasma
-
Identification and toxicological evaluation of cyclic sulfonium ion degradation products of sulphur mustard
Authors: P Hemström, KH Holmgren, BE Hammarströ, A Larsson, A Östin
Mar. Environ. Res., 2020-08-07;162(0):105047.
Species: Human
Sample Types: Cell Culture Supernates
-
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells
Authors: M Passariell, C Vetrei, E Sasso, G Froechlich, C Gentile, AM D'Alise, N Zambrano, E Scarselli, A Nicosia, C De Lorenzo
Cancers (Basel), 2020-08-06;12(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-1
Authors: T Maekawa, H Tamura, H Domon, T Hiyoshi, T Isono, D Yonezawa, N Hayashi, N Takahashi, K Tabeta, T Maeda, M Oda, A Ziogas, V? Alexaki, T Chavakis, Y Terao, G Hajishenga
JCI Insight, 2020-08-06;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells
Authors: AE Wyman, TTT Nguyen, P Karki, ME Tulapurkar, CO Zhang, J Kim, TG Feng, AJ Dabo, NW Todd, IG Luzina, P Geraghty, RF Foronjy, JD Hasday, AA Birukova, SP Atamas, KG Birukov
Sci Rep, 2020-07-27;10(1):12497.
Species: Human
Sample Types: Cell Culture Supernates
-
Matrix metalloproteinase-7 could be a predictor for acute inflammation in psoriatic patients
Authors: A Abbes, Y Zayani, W Zidi, MB Hammami, A Mebazaa, D El Euch, A Ben Ammar, H Sanhaji, MV El May, M Mokni, M Feki, M Allal-Elas
Cytokine, 2020-07-11;134(0):155195.
Species: Human
Sample Types: Serum
-
The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore
Authors: S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski
Front Pharmacol, 2020-07-03;11(0):983.
Species: Human
Sample Types: Cell Culture Supernates
-
Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival
Authors: HF Hazlett, TH Hampton, DS Aridgides, DA Armstrong, JA Dessaint, DL Mellinger, AB Nymon, A Ashare
Sci Rep, 2020-07-02;10(1):10935.
Species: Human
Sample Types: Cell Culture Supernates
-
Reprogramming of profibrotic macrophages for treatment of bleomycin-induced pulmonary fibrosis
Authors: F Zhang, EA Ayaub, B Wang, E Puchulu-Ca, YH Li, SU Hettiarach, SD Lindeman, Q Luo, S Rout, M Srinivasar, A Cox, K Tsoyi, C Nickerson-, IO Rosas, PS Low
EMBO Mol Med, 2020-06-29;0(0):e12034.
Species: Human
Sample Types: Cell Culture Supernates
-
Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS
Authors: W Abate, H Alrammah, M Kiernan, AJ Tonks, SK Jackson
Sci Rep, 2020-06-25;10(1):10355.
Species: Human
Sample Types: Cell Culture Supernates
-
Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells
Authors: A Allen, N Vaninov, M Li, S Nguyen, P Igo, AW Tilles, B O'Rourke, BLK Miller, B Parekkadan, RN Barcia
Sci Rep, 2020-06-23;10(1):10142.
Species: Human
Sample Types: Cell Culture Supernates
-
TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies
Authors: LM Gierman, GB Silva, Z Pervaiz, JJ Rakner, SB Mundal, AJ Thaning, I Nervik, M Elschot, S Mathew, LCV Thomsen, L Bjørge, AC Iversen
J. Leukoc. Biol., 2020-06-23;0(0):.
Species: Human
Sample Types: Placental Supernates
-
The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification
Authors: E Zuccolo, I Badi, F Scavello, I Gambuzza, L Mancinelli, F Macrì, CC Tedesco, F Veglia, AR Bonfigli, F Olivieri, A Raucci
Int J Mol Sci, 2020-06-23;21(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
Data describing expression of formyl peptide receptor 2 in human articular chondrocytes
Authors: A Strid Holm, CA Jonsson, M Mohaddes, C Lundqvist, H Forsman, I Gjertsson, K Önnheim
Data Brief, 2020-06-16;31(0):105866.
Species: Human
Sample Types: Cell Culture Supernates
-
OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion
Authors: T O'Loughlin, AJ Kruppa, ALR Ribeiro, JR Edgar, A Ghannam, AM Smith, F Buss
J. Cell. Sci., 2020-06-15;0(0):.
Species: Human
Sample Types: Tissue Culture Supernates
-
Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide
Authors: N Schwarz, S Tumpara, S Wrenger, E Ercetin, J Hamacher, T Welte, S Janciauski
Sci Rep, 2020-06-12;10(1):9563.
Species: Human
Sample Types: Cell Culture Supernates
-
Berberine Inhibits Pro-inflammatory Cytokine-induced IL-6 and CCL11 Production via Modulation of STAT6 Pathway in Human Bronchial Epithelial Cells
Authors: J Ma, CC Chan, WC Huang, ML Kuo
Int J Med Sci, 2020-06-08;17(10):1464-1473.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-inflammatory effect of Salsola komarovii extract with dissociated glucocorticoid activity
Authors: JH Seo, MH Jin, YH Chang
BMC Complement Med Ther, 2020-06-05;20(1):176.
Species: Human
Sample Types: Cell Culture Supernates
-
Trans IL-6 signaling does not appear to play a role in renal scarring after urinary tract infection
Authors: S Gupta, GY Junquera, L Nicassio, B Becknell, CB Ching
J Pediatr Urol, 2020-05-29;0(0):.
Species: Human
Sample Types: Urine
-
Sex Differences in Proatherogenic Cytokine Levels
Authors: S Bernardi, B Toffoli, F Tonon, M Francica, E Campagnolo, T Ferretti, S Comar, F Giudici, E Stenner, B Fabris
Int J Mol Sci, 2020-05-29;21(11):.
Species: Human
Sample Types:
-
Oral administration of ferulic acid or ethyl ferulate attenuates retinal damage in sodium iodate-induced retinal degeneration mice
Authors: M Kohno, K Musashi, HO Ikeda, T Horibe, A Matsumoto, K Kawakami
Sci Rep, 2020-05-26;10(1):8688.
Species: Human
Sample Types: Cell Culture Supernates
-
Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a beta-Adrenoreceptor-Dependent Mechanism
Authors: P B?yszczuk, C Zuppinger, A Costa, D Nurzynska, FD Di Meglio, M Stellato, I Agarkova, GL Smith, O Distler, G Kania
Cells, 2020-05-20;9(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses
Authors: L Mercurio, CM Failla, L Capriotti, C Scarponi, F Facchiano, M Morelli, S Rossi, G Pagnanelli, C Albanesi, A Cavani, S Madonna
PLoS ONE, 2020-04-30;15(4):e0222969.
Species: Human
Sample Types: Cell Culture Supernates
-
The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by &beta-Glucan
Authors: ST Keating, L Groh, CDCC van der He, H Rodriguez, JC Dos Santos, S Fanucchi, J Okabe, H Kaipananic, JH van Puffel, L Helder, MP Noz, V Matzaraki, Y Li, LCJ de Bree, VACM Koeken, SJCFM Moorlag, VP Mourits, J Domínguez-, M Oosting, EP Bulthuis, WJH Koopman, M Mhlanga, A El-Osta, LAB Joosten, MG Netea, NP Riksen
Cell Rep, 2020-04-21;31(3):107548.
Species: Human
Sample Types: Cell Culture Supernates
-
Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-&kappaB Signaling Pathway in Hepatic Stellate Cells
Authors: YH Wang, FM Suk, CL Liu, TL Chen, YC Twu, MH Hsu, YJ Liao
Front Pharmacol, 2020-03-31;11(0):388.
Species: Human
Sample Types: Cell Culture Supernates
-
Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma
Authors: R Gopalakris, H Matta, S Choi, PM Chaudhary
Sci Rep, 2020-03-31;10(1):5712.
Species: Mouse
Sample Types: Plasma
-
Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G
Authors: W Liu, C Li, FCK Tan, HJ Neo, YH Chan, CM Low, TL Lee
BMC Anesthesiol, 2020-03-25;20(1):69.
Species: Human
Sample Types: Cell Culture Supernates
-
Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis
Authors: JH Ko, HJ Kim, HJ Jeong, HJ Lee, JY Oh
Cell Rep, 2020-03-17;30(11):3806-3820.e6.
Species: Human
Sample Types: Cell Culture Supernates
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Dexamethasone Loaded Liposomes by Thin-Film Hydration and Microfluidic Procedures: Formulation Challenges
Authors: MD Al-Amin, F Bellato, F Mastrotto, M Garofalo, A Malfanti, S Salmaso, P Caliceti
Int J Mol Sci, 2020-02-26;21(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Monocytes from neonates and adults have a similar capacity to adapt their cytokine production after previous exposure to BCG and beta-glucan
Authors: R Namakula, LCJ de Bree, TH A Tvedt, MG Netea, S Cose, K Hanevik
PLoS ONE, 2020-02-21;15(2):e0229287.
Species: Human
Sample Types: Serum
-
1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis
Authors: H Kim, S Baek, SM Hong, J Lee, SM Jung, J Lee, M Cho, SK Kwok, SH Park
J. Korean Med. Sci., 2020-02-17;35(6):e40.
Species: Human
Sample Types: Cell Culture Supernates
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Are the Immune Properties of Mesenchymal Stem Cells from Wharton's Jelly Maintained during Chondrogenic Differentiation?
Authors: C Voisin, G Cauchois, L Reppel, C Laroye, L Louarn, C Schenowitz, P Sonon, I Poras, V Wang, E D Carosell, N Benkirane-, P Moreau, N Rouas-Frei, D Bensoussan, C Huselstein
J Clin Med, 2020-02-04;9(2):.
Species: Human
Sample Types: Cell Culture Supernates
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The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
Authors: T Furukawa, N van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, R Fortune-Gr, S Rahman, JM Gilsenan, E Houlder, CH Kowalski, S Raj, S Paul, P Cook, JE Parker, S Kelly, RA Cramer, JP Latgé, S Moye-Rowle, E Bignell, P Bowyer, MJ Bromley
Nat Commun, 2020-01-22;11(1):427.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
Authors: I Gomez, B Ward, C Souilhol, C Recarti, M Ariaans, J Johnston, A Burnett, M Mahmoud, LA Luong, L West, M Long, S Parry, R Woods, C Hulston, B Benedikter, C Niespolo, R Bazaz, S Francis, E Kiss-Toth, M van Zandvo, A Schober, P Hellewell, PC Evans, V Ridger
Nat Commun, 2020-01-10;11(1):214.
Species: Human
Sample Types: Cell Culture Supernates
-
Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile
Authors: S Queckbörne, E Syk Lundbe, K Gemzell-Da, LC Davies
Stem Cell Res Ther, 2020-01-06;11(1):15.
Species: Human
Sample Types: Cell culture supernat
-
Changes in monocyte subsets are associated with clinical outcomes in severe malarial anaemia and cerebral malaria
Authors: J Royo, M Rahabi, C Kamaliddin, S Ezinmegnon, D Olagnier, H Authier, A Massougbod, J Alao, Y Ladipo, P Deloron, G Bertin, B Pipy, A Coste, A Aubouy
Sci Rep, 2019-11-26;9(1):17545.
Species: Human
Sample Types: Plasma
-
Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
Invest. Ophthalmol. Vis. Sci., 2019-11-01;60(14):4820-4829.
Species: Human
Sample Types: Whole Cells
-
Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
BMC Sports Sci Med Rehabil, 2019-10-18;11(0):23.
Species: Human
Sample Types: Saliva
-
Targeting TGFbetaR2-mutant tumors exposes vulnerabilities to stromal TGFbeta blockade in pancreatic cancer
Authors: H Huang, Y Zhang, V Gallegos, N Sorrelle, MM Zaid, J Toombs, W Du, S Wright, M Hagopian, Z Wang, AN Hosein, AA Sathe, C Xing, EJ Koay, KE Driscoll, RA Brekken
EMBO Mol Med, 2019-10-14;0(0):e10515.
Species: Human
Sample Types: Tissue Lysates
-
Diverse Human VH antibody fragments with bio-therapeutic properties from the Crescendo Mouse
Authors: Y Teng, JL Young, B Edwards, P Hayes, L Thompson, C Johnston, C Edwards, Y Sanders, M Writer, D Pinto, Y Zhang, M Roode, P Chovanec, L Matheson, AE Corcoran, A Fernandez, L Montoliu, B Rossi, V Tosato, K Gjuracic, D Nikitin, C Bruschi, B McGuinness, T Sandal, M Romanos
N Biotechnol, 2019-10-07;55(0):65-76.
Species: Human
Sample Types: Cell Culture Supernates
-
Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
MBio, 2019-09-24;10(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Omega-3 Fatty Acid-Derived Resolvin D2 Regulates Human Placental Vascular Smooth Muscle and Extravillous Trophoblast Activities
Authors: A Ulu, PK Sahoo, AG Yuil-Valde, M Mukherjee, M Van Ormer, PG Muthuraj, M Thompson, A Anderson B, CK Hanson, SK Natarajan, TM Nordgren
Int J Mol Sci, 2019-09-07;20(18):.
Species: Human
Sample Types: Cell Culture Supernates
-
β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
Authors: JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten
Cell Rep, 2019-09-03;28(10):2659-2672.e6.
Species: Human
Sample Types: Cell Culture Supernates
-
Th1/17-Biased Inflammatory Environment Associated with COPD Alters the Response of Airway Epithelial Cells to Viral and Bacterial Stimuli
Authors: Y Chen, RK Kumar, PS Thomas, C Herbert
Mediators Inflamm., 2019-08-25;2019(0):7281462.
Species: Human
Sample Types: Cell Culture Supernates
-
Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis
Authors: M Diani, F Casciano, L Marongiu, M Longhi, A Altomare, PD Pigatto, P Secchiero, R Gambari, G Banfi, AA Manfredi, G Altomare, F Granucci, E Reali
Sci Rep, 2019-07-26;9(1):10870.
Species: Human
Sample Types: Serum
-
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
Authors: CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, C Solórzano, M Noursadegh, JS Brown, DM Ferreira, RS Heyderman
Nat Commun, 2019-07-16;10(1):3060.
Species: Human
Sample Types: Cell Culture Supernates
-
Translational regulation contributes to the secretory response of chondrocytic cells following exposure to interleukin-1 β
Authors: BT McDermott, MJ Peffers, B McDonagh, SR Tew
J. Biol. Chem., 2019-07-12;294(35):13027-13039.
Species: Human
Sample Types: Cell Culture Supernates
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Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes
Authors: S Martínez-H, V Sánchez-Ga, A Herrero-Ce, Á Vinué, JT Real, JF Ascaso, DJ Burks, H González-N
J Transl Med, 2019-07-12;17(1):222.
Species: Human
Sample Types: Plasma
-
Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA
Authors: J Russick, S Delignat, P Milanov, O Christophe, G Boros, CV Denis, PJ Lenting, SV Kaveri, S Lacroix-De
Haematologica, 2019-07-09;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells
Authors: J Hyun, RS McMahon, AL Lang, JS Edwards, AD Badilla, ME Greene, GW Stone, S Pallikkuth, M Stevenson, DM Dykxhoorn, S Kottilil, S Pahwa, E Thomas
PLoS Pathog., 2019-07-01;15(7):e1007883.
Species: Human
Sample Types: Cell Culture Supernates
-
Angiogenic and Arthritogenic Properties of the Soluble Form of CD13
Authors: Y Du, C Lu, RL Morgan, WA Stinson, PL Campbell, E Cealey, W Fu, NJ Lepore, JL Hervoso, H Cui, AG Urquhart, JN Lawton, KC Chung, DA Fox, MA Amin
J. Immunol., 2019-06-12;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
Authors: H Fleury, N Malaquin, V Tu, S Gilbert, A Martinez, MA Olivier, A Sauriol, L Communal, K Leclerc-De, E Carmona, D Provencher, AM Mes-Masson, F Rodier
Nat Commun, 2019-06-11;10(1):2556.
Species: Human
Sample Types: Cell Culture Supernates
-
Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16
Authors: M Ma, CM Percopo, DE Sturdevant, AC Sek, HD Komarow, HF Rosenberg
J. Immunol., 2019-06-10;0(0):.
Species: Human
Sample Types: Cell Lysates
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Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection
Authors: I Santecchia, F Vernel-Pau, O Rasid, J Quintin, M Gomes-Sole, IG Boneca, C Werts
PLoS Pathog., 2019-05-20;15(5):e1007811.
Species: Human
Sample Types: Cell Culture Supernates
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A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer
Authors: M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek
Cancers (Basel), 2019-05-13;11(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Systemic inflammation is associated with malaria and preterm birth in women living with HIV on antiretrovirals and co-trimoxazole
Authors: CR McDonald, AM Weckman, AL Conroy, P Olwoch, P Natureeba, MR Kamya, DV Havlir, G Dorsey, KC Kain
Sci Rep, 2019-05-01;9(1):6758.
Species: Human
Sample Types: Plasma
-
Evolving understanding of cardiovascular, cerebrovascular and peripheral arterial disease in people living with HIV and role of novel biomarkers. A study of the Spanish CoRIS cohort, 2004-2015
Authors: M Masiá, S Padilla, JA García, J García-Abe, M Fernández, I Bernardino, M Montero, J Peraire, B Pernas, F Gutiérrez
PLoS ONE, 2019-04-26;14(4):e0215507.
Species: Human
Sample Types: Plasma
-
Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis
Authors: MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay
Sci Rep, 2019-04-15;9(1):6020.
Species: Human
Sample Types: Cell Culture Supernates
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Circulating growth/differentiation factor 15 is associated with human CD56bright natural killer cell dysfunction and nosocomial infection in severe systemic inflammation
Authors: H Kleinertz, M Hepner-Sch, S Ehnert, M Claus, R Halbgebaue, L Boller, M Huber-Lang, P Cinelli, C Kirschning, S Flohé, A Sander, C Waydhas, S Vonderhage, M Jäger, M Dudda, C Watzl, SB Flohé
EBioMedicine, 2019-04-13;0(0):.
Species: Human
Sample Types: Serum
-
25(OH)D3 and 1.25(OH)2D3 inhibits TNF-? expression in human monocyte derived macrophages
Authors: A Rafique, L Rejnmark, L Heickendor, HJ Møller
PLoS ONE, 2019-04-12;14(4):e0215383.
Species: Human
Sample Types: Cell Culture Supernates
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Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
PLoS Pathog., 2019-04-09;15(4):e1007689.
Species: Human
Sample Types: Cell Culture Supernates
-
Secondhand smoke exposure and sleep-related breathing problems in toddlers
Authors: JA Groner, L Nicholson, H Huang, JA Bauer
Acad Pediatr, 2019-04-05;0(0):.
Species: Human
Sample Types: Serum
-
Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes
Authors: K Bendí?ková, F Tidu, M De Zuani, MH Kohoutková, I Andrej?ino, A Pompeiano, S B?lášková, G Forte, T Zelante, J Fri?
J. Leukoc. Biol., 2019-04-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
Authors: C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong
Mol. Cancer, 2019-03-30;18(1):64.
Species: Human
Sample Types: Cell Culture Supernates
-
An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation
Authors: C Harris, SD Thorpe, S Rushwan, W Wang, CL Thompson, JL Peacock, MM Knight, B Gooptu, A Greenough
J Biomech, 2019-03-22;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists
Authors: R Gramlich, E Aliahmadi, M Peiser
Int J Mol Sci, 2019-03-19;20(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
Authors: RM Ray, MF Maritz, C Avenant, M Tomasicchi, S Dlamini, Z van der Sp, JP Hapgood
Sci Rep, 2019-03-13;9(1):4334.
Species: Human
Sample Types: Tissue Culture Supernates
-
Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
Sci Rep, 2019-03-12;9(1):4293.
Species: Human
Sample Types: Cell Culture Supernates
-
R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation
Authors: F Abdallah, G Lecellier, P Raharivelo, C Pichon
Sci Rep, 2019-03-11;9(1):4132.
Species: Human
Sample Types: Cell Culture Supernates
-
Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells
Authors: A Islam, I Urbarova, JA Bruun, I Martinez-Z
Eur Cell Mater, 2019-02-20;37(0):153-174.
Species: Human
Sample Types: Cell Culture Supernates
-
Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection
Authors: S Vangeti, J Gertow, M Yu, S Liu, F Baharom, S Scholz, D Friberg, M Starkhamma, A Ahlberg, A Smed-Sören
J. Immunol., 2019-02-13;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Cancer-associated fibroblasts induce epithelial-mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
Authors: CR Goulet, A Champagne, G Bernard, D Vandal, S Chabaud, F Pouliot, S Bolduc
BMC Cancer, 2019-02-11;19(1):137.
Species: Human
Sample Types: Cell Culture Supernates
-
D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells
Authors: I Ugele, ZE Cárdenas-C, K Hammon, M Wehrstein, C Bruss, K Peter, K Singer, E Gottfried, J Boesch, P Oefner, K Dettmer, K Renner, M Kreutz
Int J Mol Sci, 2019-02-10;20(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
Authors: CR Ojha, M Rodriguez, MKM Karuppan, J Lapierre, F Kashanchi, N El-Hage
PLoS ONE, 2019-02-08;14(2):e0208543.
Species: Human
Sample Types: Cell Culture Supernates
-
Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5
Authors: S Giuliano, M Dufies, PD Ndiaye, J Viotti, D Borchielli, J Parola, V Vial, Y Cormerais, M Ohanna, V Imbert, E Chamorey, N Rioux-Lecl, A Savina, JM Ferrero, B Mograbi, G Pagès
Theranostics, 2019-01-30;9(4):1181-1199.
Species: Human
Sample Types: Cell Culture Supernates
-
Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells
Authors: R Saga, K Hasegawa, K Murata, M Chiba, T Nakamura, K Okumura, E Tsuruga, Y Hosokawa
Oncol Lett, 2019-01-29;17(3):3555-3561.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial
Authors: RK Cardoso, AM Araujo, RB Orcy, M Bohlke, JP Oses, FB Del Vecchi, FC Barcellos, MC Gonzalez, AJ Rombaldi
MethodsX, 2019-01-23;6(0):190-198.
Species: Human
Sample Types: Serum
-
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
Authors: EA Ebbing, AP van der Za, A Steins, A Creemers, S Hermsen, R Rentenaar, M Klein, C Waasdorp, GKJ Hooijer, SL Meijer, KK Krishnadat, CJA Punt, MI van Berge, SS Gisbertz, OM van Delden, MCCM Hulshof, JP Medema, HWM van Laarho, MF Bijlsma
Proc. Natl. Acad. Sci. U.S.A., 2019-01-22;0(0):.
Species: Human
Sample Types: Serum
-
Blood inflammatory and endothelial markers in women with von Willebrand disease
Authors: I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints
PLoS ONE, 2019-01-10;14(1):e0210544.
Species: Human
Sample Types: Plasma
-
High expression of S100 calgranulin genes in peripheral blood mononuclear cells from patients with Takayasu arteritis
Authors: J Kabeerdoss, M Thomas, R Goel, H Mohan, S Danda, J L, D Danda
Cytokine, 2018-12-26;114(0):61-66.
Species: Human
Sample Types: Cell Culture Supernates
-
A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
Authors: M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos
Cell Rep, 2018-12-26;25(13):3706-3720.e8.
Species: Human
Sample Types: Cell Culture Supernates
-
Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
Authors: MH Kubala, V Punj, VR Placencio-, H Fang, GE Fernandez, R Sposto, YA DeClerck
Cell Rep, 2018-11-20;25(8):2177-2191.e7.
Species: Human
Sample Types: Cell Culture Supernates
-
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
Authors: LBS Hansen, HM Roager, NB Søndertoft, RJ Gøbel, M Kristensen, M Vallès-Col, S Vieira-Sil, S Ibrügger, MV Lind, RB Mærkedahl, MI Bahl, ML Madsen, J Havelund, G Falony, I Tetens, T Nielsen, KH Allin, HL Frandsen, B Hartmann, JJ Holst, MH Sparholt, J Holck, A Blennow, JM Moll, AS Meyer, C Hoppe, JH Poulsen, V Carvalho, D Sagnelli, MD Dalgaard, AF Christense, MC Lydolph, AB Ross, S Villas-Bôa, S Brix, T Sicheritz-, K Buschard, A Linneberg, JJ Rumessen, CT Ekstrøm, C Ritz, K Kristianse, HB Nielsen, H Vestergaar, NJ Færgeman, J Raes, H Frøkiær, T Hansen, L Lauritzen, R Gupta, TR Licht, O Pedersen
Nat Commun, 2018-11-13;9(1):4630.
Species: Human
Sample Types: Cell Culture Supernates
-
Overproduction of IL-6 and Type-I IFN in a Lethal Case of Chikungunya Virus Infection in an Elderly Man During the 2017 Italian Outbreak
Authors: F Colavita, S Vita, E Lalle, F Carletti, L Bordi, D Vincenti, I Pozzetto, M Aiuti, F Vairo, MR Capobianch, M Lichtner, C Castillett
Open Forum Infect Dis, 2018-10-25;5(11):ofy276.
Species: Human
Sample Types: Plasma
-
The effect of compressive force combined with mechanical vibration on human alveolar bone osteoblasts
Authors: C Chatmahamo, A Pravithara, S Suttapreya, C Leethanaku
J Oral Biol Craniofac Res, 2018-10-16;9(1):81-85.
Species: Human
Sample Types: Cell Culture Supernates
-
Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury
Authors: N Shologu, M Scully, JG Laffey, D O'Toole
Int J Mol Sci, 2018-09-30;19(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
Nat Commun, 2018-09-11;9(1):3686.
Species: Human
Sample Types: Cell Culture Supernates
-
Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease
Authors: S Yi, R Chang, J Hu, Y Qiu, Q Wang, Q Cao, G Yuan, G Su, C Zhou, Y Wang, A Kijlstra, P Yang
Invest. Ophthalmol. Vis. Sci., 2018-09-04;59(11):4662-4669.
Species: Human
Sample Types: Cell Culture Supernates
-
Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
Biol. Reprod., 2018-09-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
Authors: AC Gross, H Cam, DA Phelps, AJ Saraf, HK Bid, M Cam, CA London, SA Winget, MA Arnold, L Brandolini, X Mo, JM Hinckley, PJ Houghton, RD Roberts
JCI Insight, 2018-08-23;3(16):.
Species: Human
Sample Types: Cell Culture Supernates
-
Crosstalk Between Nuclear Glucose-Regulated Protein 78 and Tumor Protein 53 Contributes to the Lipopolysaccharide Aggravated Apoptosis of Endoplasmic Reticulum Stress-Responsive Porcine Intestinal Epithelial Cells
Authors: Q Jiang, G Liu, J Chen, K Yao, Y Yin
Cell. Physiol. Biochem., 2018-08-17;48(6):2441-2455.
Species: Porcine
Sample Types: Cell Culture Supernates
-
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
Nat Commun, 2018-08-15;9(1):3267.
Species: Human
Sample Types: Cell Culture Supernates
-
Annexin A1, FPR2/ALX, and inflammatory cytokine expression in peritoneal endometriosis
Authors: LK Volpato, VV Horewicz, F Bobinski, DF Martins, AP Piovezan
J. Reprod. Immunol., 2018-08-03;129(0):30-35.
Species: Human
Sample Types: Peritoneal Fluid
-
Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
Authors: R Narasimhan, R Coras, SB Rosenthal, SR Sweeney, A Lodi, S Tiziani, D Boyle, A Kavanaugh, M Guma
Arthritis Res. Ther., 2018-08-03;20(1):164.
Species: Human
Sample Types: Serum
-
Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
Authors: P Daull, S Guenin, V Hamon de A, JS Garrigue
Mol. Vis., 2018-07-20;24(0):459-470.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of Proteasome Activity Upregulates IL-6 Expression in RPE Cells through the Activation of P38 MAPKs
Authors: T Qin, S Gao
J Ophthalmol, 2018-07-12;2018(0):5392432.
Species: Human
Sample Types: Cell Culture Supernates
-
Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands
Authors: D Tör?csik, D Kovács, S Póliska, Z Szentkeres, M Lovászi, K Hegyi, A Szegedi, CC Zouboulis, M Ståhle
PLoS ONE, 2018-06-21;13(6):e0198323.
Species: Human
Sample Types: Cell Culture Supernates
-
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
Authors: I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, D Clancy, J Brezinova, T Hu, A Bileck, C Gerner, A Bolado, A von Kriegs, SJ Martin, F Steinberg, K Strisovsky, C Adrain
Elife, 2018-06-13;7(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance
Authors: A Le Naour, R Mevel, B Thibault, E Courtais, E Chantalat, JP Delord, B Couderc, J Guillermet, A Martinez
Oncotarget, 2018-06-05;9(43):27220-27232.
Species: Human
Sample Types: Serum
-
Human cytomegalovirus replication induces endothelial cell interleukin-11
Authors: KLR Gustafsson, T Renné, C Söderberg-, LM Butler
Cytokine, 2018-05-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Plasma inflammatory and immune proteins as predictors of intra-amniotic infection and spontaneous preterm delivery in women with preterm labor: a retrospective study
Authors: H Park, KH Park, YM Kim, SY Kook, SJ Jeon, HN Yoo
BMC Pregnancy Childbirth, 2018-05-09;18(1):146.
Species: Human
Sample Types: Amniotic Fluid
-
Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis
Authors: M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov
Nature, 2018-04-18;556(7702):501-504.
Species: Human
Sample Types: Cell Culture Supernates
-
CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
Oncol Lett, 2018-04-17;15(6):9075-9080.
Species: Human
Sample Types: Cell Culture Supernates
-
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration
Authors: MA Hjort, H Hov, P Abdollahi, EN Vandsemb, UM Fagerli, B Lund, TS Slørdahl, M Børset, TB Rø
Exp Hematol Oncol, 2018-04-10;7(0):8.
Species: Human
Sample Types: Cell Culture Supernates
-
Caspase-2 associates with FAN through direct interaction and overlapping functionality
Authors: J Forsberg, X Li, AV Zamaraev, T Panaretaki, B Zhivotovsk, M Olsson
Biochem. Biophys. Res. Commun., 2018-04-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function
Authors: TM Nordgren, KL Bailey, AJ Heires, D Katafiasz, DJ Romberger
Toxicol. Sci., 2018-04-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Variable localization of Toll-like receptors in human fallopian tube epithelial cells
Authors: F Amjadi, Z Zandieh, E Salehi, R Jafari, N Ghasemi, A Aflatoonia, A Fazeli, R Aflatoonia
Clin Exp Reprod Med, 2018-03-30;45(1):1-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
Authors: J Lucifora, M Bonnin, L Aillot, F Fusil, S Maadadi, L Dimier, M Michelet, O Floriot, A Ollivier, M Rivoire, M Ait-Gougho, S Daffis, SP Fletcher, A Salvetti, FL Cosset, F Zoulim, D Durantel
Sci Rep, 2018-03-29;8(1):5390.
Species: Human
Sample Types: Cell Culture Supernates
-
Interaction between Toll-Like Receptor 9-CpG Oligodeoxynucleotides and Hepatitis B Virus Virions Leads to Entry Inhibition in Hepatocytes and Reduction of Alpha Interferon Production by Plasmacytoid Dendritic Cells
Authors: L Aillot, M Bonnin, M Ait-Gougho, N Bendriss-V, S Maadadi, L Dimier, M Subic, C Scholtes, I Najera, F Zoulim, J Lucifora, D Durantel
Antimicrob. Agents Chemother., 2018-03-27;62(4):.
Species: Human
Sample Types: Cell Culture Supernates
-
Diabetes mellitus secondary to pancreatic diseases (type 3c): The effect of smoking on the exocrine-endocrine interactions of the pancreas
Authors: M ?liwi?ska-, S Milnerowic, H Milnerowic
Diab Vasc Dis Res, 2018-03-21;0(0):1479164118764.
Species: Human
Sample Types: Whole Cells
Applications: ELISA Detection -
Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement
Authors: A Lescoat, A Ballerie, Y Augagneur, C Morzadec, L Vernhet, O Fardel, P Jégo, S Jouneau, V Lecureur
Int J Mol Sci, 2018-03-17;19(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Epicutaneous administration of the pattern recognition receptor agonist polyinosinic-polycytidylic acid activates the MDA5/MAVS pathway in Langerhans cells
Authors: P Tajpara, C Schuster, E Schön, P Kienzl, M Vierhapper, M Mildner, A Elbe-Bürge
FASEB J., 2018-03-06;0(0):fj201701090R.
Species: Human
Sample Types: Cell Culture Supernates
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Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease
Authors: Q Zhang, H Li, S Hou, H Yu, G Su, B Deng, J Qi, C Zhou, A Kijlstra, P Yang
Br J Ophthalmol, 2018-03-03;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
Authors: Z Zeng, M Li, J Chen, Q Li, Q Ning, J Zhao, Y Xu, J Xie, J Yu
Int J Chron Obstruct Pulmon Dis, 2018-02-28;13(0):703-715.
Species: Human
Sample Types: Cell Cultuer Supernates
-
Dysregulated invertebrate tropomyosin-dectin-1 interaction confers susceptibility to allergic diseases
Authors: N Gour, S Lajoie, U Smole, M White, D Hu, P Goddard, S Huntsman, C Eng, A Mak, S Oh, JH Kim, A Sharma, S Plante, IH Salem, Y Resch, X Xiao, N Yao, A Singh, S Vrtala, J Chakir, EG Burchard, AP Lane, M Wills-Karp
Sci Immunol, 2018-02-23;3(20):.
Species: Human
Sample Types: Cell Culture Supernates
-
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
Authors: F Mizoguchi, K Slowikowsk, K Wei, JL Marshall, DA Rao, SK Chang, HN Nguyen, EH Noss, JD Turner, BE Earp, PE Blazar, J Wright, BP Simmons, LT Donlin, GD Kalliolias, SM Goodman, VP Bykerk, LB Ivashkiv, JA Lederer, N Hacohen, PA Nigrovic, A Filer, CD Buckley, S Raychaudhu, MB Brenner
Nat Commun, 2018-02-23;9(1):789.
Species: Human
Sample Types: Cell Culture Supernates
-
Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
Invest. Ophthalmol. Vis. Sci., 2018-02-01;59(2):1158-1166.
Species: Human
Sample Types: Cell Culture Supernates
-
EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
Authors: A Rutkowska, DR Shimshek, AW Sailer, KK Dev
Neuropharmacology, 2018-01-31;133(0):121-128.
Species: Human
Sample Types: Cell Culture Supernates
-
Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression
Authors: CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan
EBioMedicine, 2018-01-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb� sorbent porous polymer beads
Authors: MC Gruda, KG Ruggeberg, P O'Sullivan, T Guliashvil, AR Scheirer, TD Golobish, VJ Capponi, PP Chan
PLoS ONE, 2018-01-25;13(1):e0191676.
Species: Human
Sample Types: Complex Sample Type
-
The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
Authors: RF Hamilton, Z Wu, S Mitra, A Holian
Int J Mol Sci, 2018-01-25;19(2):.
Species: Human
Sample Types: Cell Culture Supernates
-
TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
Eur Cell Mater, 2018-01-19;35(0):13-24.
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Hemolysis and Inflammatory Response to Extracorporeal Circulation during On-Pump CABG: Comparison between Roller and Centrifugal Pump Systems
Authors: AC Passaroni, ML Felicio, NLKL Campos, MAM Silva, WB Yoshida
Braz J Cardiovasc Surg, 2018-01-01;33(1):64-71.
Species: Human
Sample Types: Plasma
-
cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner
Authors: A Paunel-Gör, M Wacker, M El Aita, S Hassan, G Schlachten, A Deppe, YH Choi, E Kuhn, TO Mehler, T Wahlers
Sci Rep, 2017-12-12;7(1):17421.
Species: Human
Sample Types: Plasma
-
Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions
Authors: M Mihajlovic, M Fedecostan, MJ Oost, SKP Steenhuis, EGWM Lentjes, I Maitimu-Sm, MJ Janssen, LB Hilbrands, R Masereeuw
Int J Mol Sci, 2017-11-26;18(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
Associations between TNFSF4, TNFSF8 and TNFSF15 and Beh�et's disease but not VKH syndrome in Han Chinese
Authors: Y Jiang, L Cheng, X Li, W Zhou, L Zhang
Oncotarget, 2017-10-23;8(62):105037-105046.
Species: Human
Sample Types: Cell Culture Supernates
-
Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine
Authors: L Aubert, M Dubus, H Rammal, C Bour, C Mongaret, C Boulagnon-, R Garnotel, C Schneider, R Rahouadj, C Laurent, SC Gangloff, F Velard, C Mauprivez, H Kerdjoudj
Int J Mol Sci, 2017-10-21;18(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy
Authors: YF Zhao, L Zhu, LJ Liu, SF Shi, JC Lv, H Zhang
BMC Nephrol, 2017-09-29;18(1):301.
Species: Human
Sample Types: Cell Culture Supernates
-
Resistin as a Prooxidant Factor and Predictor of Endothelium Damage in Patients with Mild Acute Pancreatitis Exposed to Tobacco Smoke Xenobiotics
Authors: M ?ciskalska, G Marek, Z Grzebienia, H Milnerowic
Mediators Inflamm., 2017-09-26;2017(0):3039765.
Species: Human
Sample Types: Plasma
-
Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets
Authors: S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi
Cell Rep, 2017-09-19;20(12):2891-2905.
Species: Human
Sample Types: Cell Culture Supernates
-
Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-? Expression
Authors: K Eriksson, A Svensson, AS Hait, K Schlüter, P Tunbäck, I Nordström, L Padyukov, JÅ Liljeqvist, TH Mogensen, SR Paludan
J. Immunol., 2017-09-11;0(0):.
Species: Human
Sample Types: Plasma
-
Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
Authors: J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard
PLoS ONE, 2017-09-07;12(9):e0184039.
Species: Human
Sample Types: Cell Culture Supernates
-
Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model
Authors: TJJ Schirris, J Jansen, M Mihajlovic, LP van den He, R Masereeuw, FGM Russel
Sci Rep, 2017-09-06;7(1):10623.
Species: Human
Sample Types: Cell Culture Supernates
-
Increased expression of Siglec-9 in chronic obstructive pulmonary disease
Authors: Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie
Sci Rep, 2017-08-31;7(1):10116.
Species: Human
Sample Types: Cell Culture Supernates
-
MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
Exp. Mol. Med., 2017-08-04;49(8):e363.
Species: Human
Sample Types: Cell Culture Supernates
-
Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
Authors: RM Petri, A Hackel, K Hahnel, CA Dumitru, K Bruderek, SB Flohe, A Paschen, S Lang, S Brandau
Stem Cell Reports, 2017-08-03;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
Authors: M Mihajlovic, LP van den He, JG Hoenderop, J Jansen, MJ Wilmer, AJF Westheim, WA Allebes, D Stamatiali, LB Hilbrands, R Masereeuw
Sci Rep, 2017-08-02;7(1):7103.
Species: Human
Sample Types: Cell Culture Supernates
-
Minocycline modulates NF?B phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells
Authors: AD Guerra, WE Rose, P Hematti, WJ Kao
Stem Cell Res Ther, 2017-07-21;8(1):171.
Species: Human
Sample Types: Cell Culture Supernates
-
Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro
Authors: BR Oh, DH Suh, D Bae, N Ha, YI Choi, HJ Yoo, JK Park, EY Lee, EB Lee, YW Song
Arthritis Res. Ther., 2017-07-03;19(1):154.
Species: Human
Sample Types: Cell Culture Supernates
-
The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells
Authors: A Hongo, N Okumura, M Nakahara, EP Kay, N Koizumi
Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3325-3334.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity
Authors: MJ Pearson, D Herndler-B, MA Tariq, TA Nicholson, AM Philp, HL Smith, ET Davis, SW Jones, JM Lord
Sci Rep, 2017-06-14;7(1):3451.
Species: Human
Sample Types: Cell Culture Supernates
-
Expression of MicroRNA in Host Cells Infected with Helicobacter pylori
Authors: JW Chung, SH Jeong, SM Lee, JH Pak, GH Lee, JY Jeong, JH Kim
Gut Liver, 2017-05-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
Sci Rep, 2017-05-12;7(1):1815.
Species: Human
Sample Types: Cell Culture Supernates
-
In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens
Authors: N Goli?, K Veljovi?, N Popovi?, J Djoki?, I Strahini?, I Mrvaljevi?, A Terzi?-Vid
BMC Microbiol., 2017-05-06;17(1):108.
Species: Human
Sample Types: Cell Culture Supernates
-
Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
Stem Cells, 2017-04-24;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Pre- and post-surgical evaluation of the inflammatory response in patients with aortic stenosis treated with different types of prosthesis
Authors: ME Soto, JL Salas, J Vargas-Bar, R Marquez, A Rodriguez-, R Bojalil-Pa, I Pérez-Torr, V Guarner-La
BMC Cardiovasc Disord, 2017-04-14;17(1):100.
Species: Human
Sample Types: Serum
-
Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype
Authors: SJ Snelling, S Bas, GJ Puskas, SG Dakin, D Suva, A Finckh, C Gabay, P Hoffmeyer, AJ Carr, A Lübbeke
PLoS ONE, 2017-04-11;12(4):e0175109.
Species: Human
Sample Types: Serum
-
Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors
Authors: SA O'Sullivan, M Velasco-Es, KK Dev
Glia, 2017-04-04;0(0):.
-
MicroRNA-320a protects against osteoarthritis cartilage degeneration by regulating the expressions of BMI-1 and RUNX2 in chondrocytes
Authors: H Peng, D Liang, B Li, C Liang, W Huang, H Lin
Pharmazie, 2017-04-01;72(4):223-226.
Species: Human
Sample Types: Cell Culture Supernates
-
Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors
Authors: AH Bryant, GE Menzies, LM Scott, S Spencer-Ha, LB Davies, RA Smith, RH Jones, CA Thornton
Clin. Exp. Immunol, 2017-03-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4
Authors: M Du, A Martin, F Hays, J Johnson, RA Farjo, KM Farjo
Mol. Vis., 2017-03-31;23(0):185-197.
Species: Human
Sample Types: Cell Culture Supernates
-
Frequency and clinical significance of short cervix in patients with preterm premature rupture of membranes
Authors: SM Lee, KH Park, EY Jung, JA Jang, HN Yoo
PLoS ONE, 2017-03-30;12(3):e0174657.
Species: Human
Sample Types: Amniotic Fluid
-
Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
Authors: L Chen, MS Eapen, GR Zosky
Sci Rep, 2017-03-27;7(0):45172.
Species: Human
Sample Types: Cell Culture Supernates
-
Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-?B acivation
Authors: Sofia Avnet
Int. J. Cancer, 2017-03-15;0(0):.
Species: Human
Sample Types: Serum
-
Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture
Authors: JW Park, KH Park, EY Jung
PLoS ONE, 2017-03-09;12(3):e0173312.
Species: Human
Sample Types: Amniotic Fluid
-
Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells
Authors: V Selvarani, S Roland, S Andy, H James
Virus Res, 2017-03-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks' Gestation or Less
Authors: EY Jung, KH Park, BR Han, SH Cho, HN Yoo, J Lee
J. Korean Med. Sci, 2017-03-01;32(3):480-487.
Species: Human
Sample Types: Amniotic Fluid
-
Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
Immun Ageing, 2017-02-22;14(0):5.
Species: Human
Sample Types: Cell Culture Supernates
-
Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
Authors: CM Henry, SJ Martin
Mol. Cell, 2017-02-16;65(4):715-729.e5.
Species: Human
Sample Types: Cell Culture Supernates
-
Improvement of cardiometabolic markers after fish oil intervention in young Mexican adults and the role of PPAR? L162V and PPAR?2 P12A
Authors: A Binia, C Vargas-Mar, M Ancira-Mor, LM Gosoniu, I Montoliu, E Gámez-Vald, DC Soria-Cont, A Angeles-Qu, R Gonzalez-A, S Fernández, D Martínez-C, B Hernández-, M Ramírez-So, C Pérez-Orte, Y Rodríguez-, I Castan, I Rubio-Alia, F Vadillo-Or, R Márquez-Ve, R Bojalil, JC López-Alva, P Valet, M Kussmann, I Silva-Zole, ME Tejero
J. Nutr. Biochem., 2017-02-10;43(0):98-106.
Species: Human
Sample Types: Serum
-
Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis
Authors: D Nicholas, EA Proctor, FM Raval, BC Ip, C Habib, E Ritou, TN Grammatopo, D Steenkamp, H Dooms, CM Apovian, DA Lauffenbur, BS Nikolajczy
PLoS ONE, 2017-02-08;12(2):e0170975.
Species: Human
Sample Types: Cell Culture Supernates
-
MODELING STROMA-INDUCED DRUG RESISTANCE IN A TISSUE-ENGINEERED TUMOR MODEL OF EWING SARCOMA
Authors: Marco Santoro
Tissue Eng Part A, 2017-01-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-?B-mediated cytokine production
Authors: Soh Yamamoto
Biochem. Biophys. Res. Commun, 2016-12-18;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
Sci Rep, 2016-12-15;6(0):39035.
Species: Human
Sample Types: Cell Culture Supernates
-
Altered Systemic Adipokines in Patients with Chronic Urticaria
Authors: Hoang Kim Tu Trinh
Int. Arch. Allergy Immunol, 2016-12-01;171(2):102-110.
Species: Human
Sample Types: Serum
-
Nitro-Oleic Acid Prevents Hypoxia- and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction
Authors: Michaela Pekarova
Cardiovasc Drugs Ther, 2016-12-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions
Oxid Med Cell Longev, 2016-11-23;2016(0):2069290.
Species: Human
Sample Types: Serum
-
Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation
Authors: Johan J F Verhoef
Biomaterials, 2016-11-21;119(0):68-77.
Species: Human
Sample Types: Cell Culture Supernates
-
Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion
PLoS ONE, 2016-11-16;11(11):e0166500.
Species: Human
Sample Types: Cell Culture Supernates
-
Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide
Sci Rep, 2016-11-14;6(0):36575.
Species: Human
Sample Types: Cell Culture Supernates
-
CD36-Mediated Uptake of Surfactant Lipids by Human Macrophages Promotes Intracellular Growth of Mycobacterium tuberculosis
J. Immunol., 2016-11-09;197(12):4727-4735.
Species: Human
Sample Types: Cell Culture Supernates
-
Biocompatibility of primers and an adhesive used for implant-retained maxillofacial prostheses: An in�vitro analysis
Authors: Daniela Micheline Dos Santos
J Prosthet Dent, 2016-11-09;0(0):.
-
Novel approach to study the cardiovascular effects and mechanism of action of urban particulate matter using lung epithelial-endothelial tetra-culture system
Authors: Kyu Hyuck Chung
Toxicol In Vitro, 2016-11-04;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts
Evid Based Complement Alternat Med, 2016-10-11;2016(0):5357689.
Species: Human
Sample Types: Cell Culture Supernates
-
Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating
J Control Release, 2016-09-26;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
Aging Cell, 2016-09-22;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages
Infect Immun, 2016-09-19;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells
Sci Rep, 2016-09-01;6(0):32505.
Applications: ChIP -
IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium
J Immunol, 2016-08-17;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum
J Immunol, 2016-07-29;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour
Sci Rep, 2016-07-22;6(0):30150.
Species: Human
Sample Types: Cell Culture Supernates
-
Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1? and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells
J Immunol, 2016-07-11;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
Authors: Mélissa Noack
Arthritis Res Ther, 2016-06-23;18(0):148.
Species: Human
Sample Types: Cell Culture Supernates
-
Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
Sci Rep, 2016-05-25;6(0):26662.
Species: Human
Sample Types: Cell Culture Supernates
-
Engineering a 3D microfluidic culture platform for tumor-treating field application
Sci Rep, 2016-05-24;6(0):26584.
Species: Human
Sample Types: Cell Culture Supernates
-
Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium
PLoS ONE, 2016-05-12;11(5):e0155161.
Species: Human
Sample Types: Cell Culture Supernates
-
Hepcidin-Induced Iron Deficiency Is Related to Transient Anemia and Hypoferremia in Kawasaki Disease Patients
Int J Mol Sci, 2016-05-12;17(5):.
Species: Human
Sample Types: Plasma
-
Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin
J Immunol, 2016-04-29;196(11):4681-91.
Species: Human
Sample Types: Cell Culture Supernates
-
Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
Sci Rep, 2016-04-25;6(0):24974.
Species: Human
Sample Types: Cell Culture Supernates
-
Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
PLoS ONE, 2016-04-05;11(4):e0153118.
Species: Human
Sample Types: Cell Culture Supernates
-
In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
Reprod Biol Endocrinol, 2015-10-07;13(0):115.
Species: Human
Sample Types: Cell Culture Supernates
-
Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
Authors: Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock I, Wort S
Respir Res, 2015-09-18;16(0):114.
Species: Human
Sample Types: Cell Culture Supernates
-
Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells.
Authors: Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K
PLoS ONE, 2015-09-18;10(9):e0138267.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin-23 Receptor Gene Polymorphism May Enhance Expression of the IL-23 Receptor, IL-17, TNF-alpha and IL-6 in Behcet's Disease.
Authors: Jiang Z, Hennein L, Tao Y, Tao L
PLoS ONE, 2015-07-29;10(7):e0134632.
Species: Human
Sample Types: Cell Culture Supernates
-
LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.
Authors: Broekman M, Roelofs H, Hoentjen F, Wiegertjes R, Stoel N, Joosten L, de Jong D, Wanten G
PLoS ONE, 2015-07-24;10(7):e0133932.
Species: Human
Sample Types: Plasma
-
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
Authors: Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C
PLoS ONE, 2015-05-08;10(5):e0126159.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma.
Authors: Fernandez-Bertolin L, Mullol J, Fuentes-Prado M, Roca-Ferrer J, Alobid I, Picado C, Pujols L
PLoS ONE, 2015-05-05;10(5):e0125443.
Species: Human
Sample Types: Cell Culture Supernates
-
Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
Authors: Sommerfelt R, Feuerherm A, Skuland T, Johansen B
PLoS ONE, 2015-04-20;10(4):e0119088.
Species: Human
Sample Types: Cell Culture Supernates
-
Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.
Authors: Puig K, Manocha G, Combs C
PLoS ONE, 2015-03-05;10(3):e0119534.
Species: Human
Sample Types: Cell Culture Supernates
-
The effects of knockdown of rho-associated kinase 1 and zipper-interacting protein kinase on gene expression and function in cultured human arterial smooth muscle cells.
Authors: Deng J, Wang X, Chen Y, O'Brien E, Gui Y, Walsh M
PLoS ONE, 2015-02-27;10(2):e0116969.
Species: Human
Sample Types: Cell Culture Supernates
-
Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
Authors: Jaguin M, Fardel O, Lecureur V
PLoS ONE, 2015-02-24;10(2):e0116560.
Species: Human
Sample Types: Cell Culture Supernates
-
BET bromodomains regulate transforming growth factor-beta-induced proliferation and cytokine release in asthmatic airway smooth muscle.
Authors: Perry M, Durham A, Austin P, Adcock I, Chung K
J Biol Chem, 2015-02-19;290(14):9111-21.
Species: Human
Sample Types: Cell Culture Supernates
-
Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.
Authors: Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C
Respir Res, 2015-02-07;16(0):14.
Species: Human
Sample Types: Cell Culture Supernates
-
SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.
Authors: Xue F, Li X, Zhao X, Wang L, Liu M, Shi R, Zheng J
PLoS ONE, 2015-02-06;10(2):e0115354.
Species: Human
Sample Types: Cell Culture Supernates
-
Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015-01-23;22(8):1313-27.
Species: Human
Sample Types: Cell Culture Supernates
-
High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M
J Virol, 2015-01-21;89(7):3859-69.
Species: Human
Sample Types: Cell Culture Supernates
-
Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
Authors: Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, Yang S, Chang N, Hung S, Lin Y
PLoS ONE, 2014-07-24;9(7):e102450.
Species: Human
Sample Types: Cell Culture Supernates
-
Bacterial siderophores that evade or overwhelm lipocalin 2 induce hypoxia inducible factor 1alpha and proinflammatory cytokine secretion in cultured respiratory epithelial cells.
Authors: Holden V, Lenio S, Kuick R, Ramakrishnan S, Shah Y, Bachman M
Infect Immun, 2014-06-30;82(9):3826-36.
Species: Human
Sample Types: Cell Culture Supernates
-
Circulating autoantibodies to endothelial progenitor cells: binding characteristics and association with risk factors for atherosclerosis.
Authors: George J, Matucci-Cerinic M, Bar I, Shimoni S
PLoS ONE, 2014-06-19;9(6):e97836.
Species: Human
Sample Types: Serum
-
Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
Authors: Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K
Cancer Res, 2014-06-16;74(16):4458-69.
Species: Human
Sample Types: Cell Culture Supernates
-
Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
J Biol Chem, 2014-05-19;289(27):19231-44.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of non-coding RNAs in maintaining primary airway smooth muscle cells.
Authors: Perry, Mark M, Tsitsiou, Eleni, Austin, Philip J, Lindsay, Mark A, Gibeon, David S, Adcock, Ian M, Chung, Kian Fan
Respir Res, 2014-05-16;15(0):58.
Species: Human
Sample Types: Cell Culture Supernates
-
A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
PLoS ONE, 2014-05-09;9(5):e96943.
Species: Human
Sample Types: Cell Culture Supernates
-
Optofluidic laser for dual-mode sensitive biomolecular detection with a large dynamic range.
Authors: Wu X, Oo M, Reddy K, Chen Q, Sun Y, Fan X
Nat Commun, 2014-04-30;5(0):3779.
Species: Human
Sample Types: Protein
-
Anti-inflammatory effects of green soybean extract irradiated with visible light.
Authors: Tanaka K, Ohgo Y, Katayanagi Y, Yasui K, Hiramoto S, Ikemoto H, Nakata Y, Miyoshi N, Isemura M, Ohashi N, Imai S
Sci Rep, 2014-04-22;4(0):4732.
Species: Human
Sample Types: Cell Culture Supernates
-
TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells.
Authors: Liu B, Cao Y, Huizinga T, Hafler D, Toes R
Eur J Immunol, 2014-04-16;44(7):2121-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Essential role for the TRF2 telomere protein in adult skin homeostasis.
Authors: Martinez P, Ferrara-Romeo I, Flores J, Blasco M
Aging Cell, 2014-04-14;13(4):656-68.
Species: Human
Sample Types: Cell Culture Supernates
-
Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.
Authors: Shah S, King E, Chandrasekhar A, Newton R
J Biol Chem, 2014-04-01;289(19):13667-79.
Species: Human
Sample Types: Cell Culture Supernates
-
Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival.
Authors: Kis-Toth K, Tsokos G
J Immunol, 2014-03-26;192(9):4436-42.
Species: Human
Sample Types: Cell Culture Supernates
-
Mycobacterium tuberculosis impairs dendritic cell functions through the serine hydrolase Hip1.
Authors: Madan-Lala R, Sia J, King R, Adekambi T, Monin L, Khader S, Pulendran B, Rengarajan J
J Immunol, 2014-03-21;192(9):4263-72.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells.
Authors: Comer D, Elborn J, Ennis M
BMC Pulm Med, 2014-03-01;14(0):32.
Species: Human
Sample Types: Cell Culture Supernates
-
Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels.
Authors: Arndts, Kathrin, Specht, Sabine, Debrah, Alexande, Tamarozzi, Francesc, Klarmann Schulz, Ute, Mand, Sabine, Batsa, Linda, Kwarteng, Alexande, Taylor, Mark, Adjei, Ohene, Martin, Coralie, Layland, Laura E, Hoerauf, Achim
PLoS Negl Trop Dis, 2014-02-20;8(2):e2679.
Species: Human
Sample Types: Cell Culture Supernates
-
RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.
Authors: Rigby R, Webb L, Mackenzie K, Li Y, Leitch A, Reijns M, Lundie R, Revuelta A, Davidson D, Diebold S, Modis Y, MacDonald A, Jackson A
EMBO J, 2014-02-10;33(6):542-58.
Species: Human
Sample Types: Cell Culture Supernates
-
Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
Authors: Zughaier, Susu M, Kandler, Justin L, Shafer, William
PLoS ONE, 2014-01-28;9(1):e87688.
Species: Human
Sample Types: Cell Culture Supernates
-
TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
Authors: Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P
PLoS ONE, 2014-01-08;9(1):e84214.
Species: Human
Sample Types: Cell Culture Supernates
-
Activin A as a mediator of NK-dendritic cell functional interactions.
Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
J Immunol, 2014-01-06;192(3):1241-8.
Species: Human
Sample Types: Whole Cells
-
Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway.
Authors: Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D
PLoS ONE, 2013-12-30;8(12):e82867.
Species: Human
Sample Types: Cell Culture Supernates
-
Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population.
Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P
Invest Ophthalmol Vis Sci, 2013-12-30;54(13):8384-92.
Species: Human
Sample Types: Cell Culture Supernates
-
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
J Immunol, 2013-12-16;192(2):722-31.
Species: Human
Sample Types: Cell Culture Supernates
-
Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
PLoS ONE, 2013-12-10;8(12):e82734.
Species: Human
Sample Types: Serum
-
Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
Cytokine, 2013-11-23;65(2):222-30.
Species: Human
Sample Types: Cell Culture Supernates
-
Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.
Authors: Wallace A, Host A, Whitley G, Cartwright J
Am J Pathol, 2013-10-06;183(6):1853-61.
Species: Human
Sample Types: Cell Culture Supernates
-
Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.
Authors: Hutchinson J, Rajagopal S, Yuan M, Norman J
FASEB J, 2013-09-27;28(1):94-105.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others?
Authors: Doble, Rosella, McDermott, Michael, Cesur, Ozlem, Stonehouse, Nicola J, Wittmann, Miriam
J Invest Dermatol, 2013-09-20;134(3):852-5.
Species: Human
Sample Types: Cell Culture Supernates
-
Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
Authors: Moh M, Lorenzini P, Gullo C, Schwarz H
FASEB J, 2013-04-25;27(8):2957-66.
Species: Human
Sample Types: Cell Culture Supernates
-
S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
PLoS ONE, 2013-04-24;8(4):e62372.
Species: Human
Sample Types: Cell Culture Supernates
-
1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes.
Authors: Ding C, Wilding J, Bing C
PLoS ONE, 2013-04-24;8(4):e61707.
Species: Human
Sample Types: Cell Culture Supernates
-
Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells.
Authors: Jeffery H, Soderberg-Naucler C, Butler L
J Virol, 2013-03-27;87(11):6530-5.
Species: Human
Sample Types: Cell Culture Supernates
-
Opposite cytokine synthesis by fibroblasts in contact co-culture with osteosarcoma cells compared with transwell co-cultures.
Authors: David M, Kelly E, Zoellner H
Cytokine, 2013-03-19;62(1):48-51.
Species: Human
Sample Types: Cell Culture Supernates
-
Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts.
Authors: Herath T, Darveau R, Seneviratne C, Wang C, Wang Y, Jin L
PLoS ONE, 2013-03-12;8(3):e58496.
Species: Human
Sample Types: Cell Culture Supernates
-
Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion.
Authors: Boyd A, Bennuru S, Wang Y, Sanprasert V, Law M, Chaussabel D, Nutman T, Semnani R
Infect Immun, 2013-02-19;81(5):1420-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease.
Authors: Alvarez J, Zughaier S, Law J, Hao L, Wasse H, Ziegler T, Tangpricha V
Eur J Clin Nutr, 2013-01-30;67(3):264-9.
Species: Human
Sample Types: Serum
-
Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
J Neuroinflammation, 2012-08-18;9(0):203.
Species: Human
Sample Types: Cell Culture Supernates
-
Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
Eur J Clin Nutr, 2012-07-18;66(9):1072-4.
Species: Human
Sample Types: Plasma
-
ERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytes.
Authors: Wilhelmsen K, Mesa K, Lucero J, Xu F, Hellman J
J Biol Chem, 2012-06-15;287(32):26478-94.
Species: Human
Sample Types: Cell Culture Supernates
-
Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.
Authors: Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL
PLoS ONE, 2012-04-24;7(4):e35866.
Species: Human
Sample Types: Cell Culture Supernates
-
Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
PLoS ONE, 2012-04-18;7(4):e34965.
Species: Human
Sample Types: Cell Culture Supernates
-
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
Authors: Suh HS, Choi N, Tarassishin L, Lee SC
PLoS ONE, 2012-04-11;7(4):e35115.
Species: Human
Sample Types: Cell Culture Supernates
-
Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti.
Authors: Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A
PLoS Negl Trop Dis, 2012-04-03;6(4):e1611.
Species: Human
Sample Types: Cell Culture Supernates
-
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
Authors: Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogne M, Moura IC, Monteiro RC
J. Exp. Med., 2012-03-26;209(4):793-806.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA
Proc. Natl. Acad. Sci. U.S.A., 2012-02-06;109(8):3001-5.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
Mucosal Immunol, 2011-12-21;5(2):140-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
Blood, 2011-09-06;118(18):5031-9.
Species: Human
Sample Types: Cell Culture Supernates
-
GLI2 Transcription Factor Mediates Cytokine Cross-talk in the Tumor Microenvironment.
Authors: Elsawa SF, Almada LL, Ziesmer SC, Novak AJ, Witzig TE, Ansell SM, Fernandez-Zapico ME
J. Biol. Chem., 2011-03-18;286(24):21524-34.
Species: Human
Sample Types: Cell Culture Supernates
-
Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6.
Authors: Eikawa S, Ohue Y, Kitaoka K
J. Immunol., 2010-11-03;185(11):6734-40.
Species: Human
Sample Types: Pleural Effusion
-
PI3K/p110{delta} is a novel therapeutic target in multiple myeloma.
Authors: Ikeda H, Hideshima T, Fulciniti M
Blood, 2010-05-26;116(9):1460-8.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
J. Immunol., 2010-03-31;184(9):4880-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease.
Authors: Khankin EV, Mutter WP, Tamez H
PLoS ONE, 2010-02-16;5(2):e9246.
Species: Human
Sample Types: Serum
-
Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
Authors: Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM
PLoS ONE, 2009-12-15;4(12):e8300.
Species: Human
Sample Types: Urine
-
Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
Authors: Correale J, Farez M
J. Immunol., 2009-10-07;183(9):5999-6012.
Species: Human
Sample Types: Cell Culture Supernates
-
Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
Authors: Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, Orinska Z, Paus R, Bulfone-Paus S, Giovarelli M
J. Immunol., 2009-08-05;183(5):3004-13.
Species: Human
Sample Types: Cell Culture Supernates
-
Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
Clin. Immunol., 2009-06-25;133(1):27-44.
Species: Human
Sample Types: Plasma
-
Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.
Authors: Damsgaard CT, Lauritzen L, Calder PC, Kjaer TR, Frokiaer H
J. Nutr., 2009-06-03;139(7):1410-4.
Species: Human
Sample Types: Cell Culture Supernates
-
TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
Eur. J. Immunol., 2009-05-01;39(5):1221-30.
Species: Human
Sample Types: Cell Culture Supernates
-
Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.
Authors: Huang QQ, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AM, Tak PP, Haines GK, Nicchitta CV, Pope RM
J. Immunol., 2009-04-15;182(8):4965-73.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009-03-02;119(10):1424-32.
Species: Human
Sample Types: Plasma
-
Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
Authors: Hao Q, Wang L, Tang H
Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7.
Species: Human
Sample Types: Cell Culture Supernates
-
Carbon dioxide inhalation causes pulmonary inflammation.
Authors: Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco AJ, Schwartz L
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-01-09;296(4):L657-65.
Species: Human
Sample Types: Cell Culture Supernates
-
Altered interleukin-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with pre-eclampsia.
Authors: Zhao S, Gu Y, Dong Q, Fan R, Wang Y
Placenta, 2008-11-05;29(12):1024-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.
Authors: Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE
Proc. Natl. Acad. Sci. U.S.A., 2008-09-16;105(38):14692-7.
Species: Human
Sample Types: Tissue Homogenates
-
Helminth infections associated with multiple sclerosis induce regulatory B cells.
Authors: Correale J, Farez M, Razzitte G
Ann. Neurol., 2008-08-01;64(2):187-99.
Species: Human
Sample Types: Cell Culture Supernates
-
Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma.
Authors: Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Mitsiades C, Chauhan D, Okawa Y, Munshi NC, Richardson PG, Anderson KC
Leukemia, 2008-07-03;22(10):1925-32.
Species: Human
Sample Types: Cell Culture Supernates
-
Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008-06-17;112(5):1822-31.
Species: Human
Sample Types: Cell Culture Supernates
-
Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
J. Immunol., 2008-05-01;180(9):6000-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes.
Authors: Weigert J, Neumeier M, Wanninger J, Wurm S, Kopp A, Schober F, Filarsky M, Schaffler A, Zeitoun M, Aslanidis C, Buechler C
FEBS Lett., 2008-04-28;582(12):1777-82.
Species: Human
Sample Types: Cell Culture Supernates
-
p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.
Authors: Ishitsuka K, Hideshima T, Neri P, Vallet S, Shiraishi N, Okawa Y, Shen Z, Raje N, Kiziltepe T, Ocio EM, Chauhan D, Tassone P, Munshi N, Campbell RM, Dios AD, Shih C, Starling JJ, Tamura K, Anderson KC
Br. J. Haematol., 2008-04-07;141(5):598-606.
Species: Human
Sample Types: Cell Culture Supernates
-
Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
J. Cell. Physiol., 2008-01-01;214(1):27-37.
Species: Human
Sample Types: Cell Culture Supernates
-
Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells.
Authors: Aydin S, Signorelli S, Lechleitner T, Joannidis M, Pleban C, Perco P, Pfaller W, Jennings P
Am. J. Physiol., Cell Physiol., 2007-12-05;294(2):C543-54.
Species: Human
Sample Types: Cell Culture Supernates
-
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
J. Clin. Invest., 2007-12-01;117(12):3664-3672.
Species: Human
Sample Types: Cell Culture Supernates
-
Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis.
Authors: Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C
J. Immunol., 2007-11-15;179(10):7166-75.
Species: Human
Sample Types: Urine
-
Cytokine response to strenuous exercise in athletes and non-athletes--an adaptive response.
Authors: Gokhale R, Chandrashekara S, Vasanthakumar KC
Cytokine, 2007-10-22;40(2):123-7.
Species: Human
Sample Types: Plasma
-
Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma.
Authors: Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Chauhan D, Munshi NC, Richardson PG, Anderson KC
Br. J. Haematol., 2007-10-01;139(1):55-63.
Species: Human
Sample Types: Cell Culture Supernates
-
Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
J. Biol. Chem., 2007-08-31;282(44):31882-90.
Species: Human
Sample Types: Cell Culture Supernates
-
Preadipocyte response and impairment of differentiation in an inflammatory environment.
Authors: Poulain-Godefroy O, Froguel P
Biochem. Biophys. Res. Commun., 2007-03-19;356(3):662-7.
Species: Human
Sample Types: Cell Culture Supernates
-
The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: potential steroid-sparing role for DHEA.
Authors: Harding G, Mak YT, Evans B, Cheung J, MacDonald D, Hampson G
Cytokine, 2006-12-11;36(1):57-68.
Species: Human
Sample Types: Cell Culture Supernates
-
Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors.
Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H
Cytokine, 2006-07-25;34(5):278-83.
Species: Human
Sample Types: Serum
-
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression.
Authors: Macagno A, Molteni M, Rinaldi A
J. Exp. Med., 2006-05-22;203(6):1481-92.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
J. Pharmacol. Exp. Ther., 2006-05-11;318(2):741-50.
Species: Human
Sample Types: Cell Culture Supernates
-
TLR3 can directly trigger apoptosis in human cancer cells.
Authors: Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T
J. Immunol., 2006-04-15;176(8):4894-901.
Species: Human
Sample Types: Cell Culture Supernates
-
Comparison of serum levels of inflammatory markers in patients with coronary vasospasm without significant fixed coronary artery disease versus patients with stable angina pectoris and acute coronary syndromes with significant fixed coronary artery disease.
Authors: Hung MJ, Cherng WJ, Cheng CW, Li LF
Am. J. Cardiol., 2006-03-27;97(10):1429-34.
Species: Human
Sample Types: Serum
-
Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
J. Immunol., 2006-03-15;176(6):3742-52.
Species: Human
Sample Types: Cell Culture Supernates
-
ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin.
Authors: Karadag A, Zhou M, Croucher PI
Blood, 2005-12-22;107(8):3271-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
Eur. J. Immunol., 2005-08-01;35(8):2459-70.
Species: Human
Sample Types: Cell Culture Supernates
-
Pre-interleukin-1alpha expression reduces cell growth and increases interleukin-6 production in SaOS-2 osteosarcoma cells: Differential inhibitory effect of interleukin-1 receptor antagonist (icIL-1Ra1).
Authors: Palmer G, Trolliet S, Talabot-Ayer D, Mezin F, Magne D, Gabay C
Cytokine, 2005-07-21;31(2):153-60.
Species: Human
Sample Types: Cell Culture Supernates
-
Microbial exposure, symptoms and inflammatory mediators in nasal lavage fluid of kitchen and clerical personnel in schools.
Authors: Lignell U, Meklin T, Putus T, Vepsalainen A, Roponen M, Torvinen E, Reeslev M, Pennanen S, Hirvonen MR, Kalliokoski P, Nevalainen A
Int J Occup Med Environ Health, 2005-01-01;18(2):139-50.
Species: Human
Sample Types: Nasal Lavage Fluid
-
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
J. Immunol., 2004-07-15;173(2):1463-76.
Species: Human
Sample Types: Cell Culture Supernates
-
Biocompatibility pattern of a bicarbonate/lactate-buffered peritoneal dialysis fluid in APD: a prospective, randomized study.
Authors: Fusshoeller A, Plail M, Grabensee B, Plum J
Nephrol. Dial. Transplant., 2004-06-22;19(8):2101-6.
Species: Human
Sample Types: Peritoneal Dialysate
-
Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes.
Authors: Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H
Inhal Toxicol, 2002-06-01;14(6):653-62.
Species: Human
Sample Types: Sputum
-
The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
Hum. Reprod., 2002-04-01;17(4):1039-45.
Species: Human
Sample Types: Peritoneal Fluid
-
IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions.
Authors: Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL
Hum. Reprod., 2002-01-01;17(1):69-75.
Species: Human
Sample Types: Peritoneal Fluid
-
Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
Authors: Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR
Eur. Respir. J., 2001-09-01;18(3):542-8.
Species: Human
Sample Types: Serum
-
Reproducibility of measurements of exhaled NO, and cell count and cytokine concentrations in induced sputum.
Authors: Purokivi M, Randell J, Hirvonen MR, Tukiainen H
Eur. Respir. J., 2000-08-01;16(2):242-6.
Species: Human
Sample Types: Sputum
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IL6 secretion was measured in the supernatant of LPS-stimulated (100 ng/ml) cultured human dendritic cells after 18 hours.
Easy protocol, good results
Monocytes were stimulated with LPS (100 ng/ml) for 24 hours. After 24 hours, IL-6 was assessed in the supernatant.
Detection of IL-6 produced by BCMA-specific CAR-T cells in response to BCMA-negative and BCMA-positive hematopoietic cell lines.
We used this kit for the quantification of IL 6 in human serum and plasma. We could not see any signals, but very well-described protocol.
Cultured Monocytes
I recommend using R&D's Ancillary Kit reagents, although in-house prepared buffers also work fine.