Human IL-26 (NP_060872) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1958
R&D Systems VersaClone cDNA Plasmids
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Human IL-26 (NP_060872) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: IL-26/AK155

IL-26 was originally cloned from herpesvirus saimiri (HVS)-transformed T-cells and named AK155. In addition to HVS-transformed T cells, IL-26 is also expressed in other virally-transformed T cell lines, fresh peripheral mononuclear cells, activated NK cells and T cells. A mouse homolog of human IL-26 has not been identified. Mature IL-26 is a homodimer in solution. IL-26 binds with high-affinity to a heterodimeric complex consisting of the ligand-binding IL-20 R alpha and non-ligand-binding IL-10 R beta. Activation of the receptor complex results in rapid phosphorylation of STAT1 and STAT3.

Long Name
Interleukin 26
Entrez Gene IDs
55801 (Human)
Alternate Names
AK155; AK155IL-26interleukin-26; IL26; IL-26; interleukin 26; Protein AK155

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