Human GATA-3 PE-conjugated Antibody Summary
Pro135-Ser258
Accession # P23771
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of GATA‑3 in MCF‑7 Human Cell Line by Flow Cytometry. MCF-7 cells were stained with Mouse Anti-Human GATA‑3 PE‑conjugated Monoclonal Antibody (Catalog # IC26051P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). View our protocol for Staining Intracellular Molecules.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: GATA-3
GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.
Product Datasheets
Citations for Human GATA-3 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 2
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Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis
Authors: SF Costa, VO Gomes, MO Dos Santos, LM Melo, GL Venturin, JP Bragato, GT Rebech, C de Oliveir, BM Nascimento, G Gileno de, VM Felix de L
PLoS Negl Trop Dis, 2020-01-21;14(1):e0008021.
Species: Canine
Sample Types: Whole Cells
Applications: Flow Cytometry -
Induction of miR 21 impairs the anti-Leishmania response through inhibition of IL-12 in canine splenic leukocytes
Authors: LM Melo, JP Bragato, GL Venturin, GT Rebech, SF Costa, LE Garcia, FL Lopes, FR Eugênio, PS Patto Dos, VMF de Lima
PLoS ONE, 2019-12-11;14(12):e0226192.
Species: Canine
Sample Types: Whole Cells
Applications: Flow Cytometry
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