Human Fc gamma RIB/CD64b (NP_001017986) VersaClone cDNA

Human Fc gamma RIB/CD64b (NP_001017986) VersaClone cDNA Summary

Specifications

Product Datasheets

Background: Fc gamma RIB/CD64b

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors.

Related Research Areas

• Acute Myeloid Leukemia
• Common Macrophage Markers
• Conventional/Classical Dendritic Cells
• Dendritic Cell Pathogen Recognition/Uptake
• Fc Receptors
• Granulocyte Markers
• Inflammatory/Monocyte-derived Dendritic Cells
• ITIM/ITAM Immunoreceptors and Related Molecules
• Leukocyte Receptors/Markers in Allergy and Asthma
• Monocyte Markers
• Mouse Tissue-Resident Macrophage Markers
• Platelet Adhesion Molecules
• Uptake of Amyloid beta by Glia Cells