Human EOMES Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: EOMES

EOMES (Eomesodermin; Eo from Greek meaning “dawn”/early in mesoderm; also TBR2) is a 72 kDa member of the TBR1 subfamily, T-box family of transcription factors. It is expressed in NK and CD8⁺ T cells, where CTLA4 activation suppresses EOMES activation of IFN-gamma and granzyme B genes. It is also found in the embryo, where it occurs in forebrain floorplate and migrating neuroblasts at 12.5 weeks gestation. Notably, it is reported to undergo intercellular transfer in fetal Xenopus tissue destined to become mesoderm. Here, it synchronizes a multicellular commitment to a cell lineage. 

Product Datasheets

Product Specific Notices

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Related Research Areas

• Definitive Endoderm Markers
• Early Endodermal Lineage Markers
• Early Mesodermal Lineage Markers
• gamma delta T Cells
• Neural Progenitor Cell Markers
• Pluripotent Stem Cell Transcription Factors
• T Cell Cytokine Signaling
• Trophoblast Stem Cell Markers