Human CXCR4 (NP_003458) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0032
R&D Systems VersaClone cDNA Plasmids
1 Image
Product Details
FAQs
Supplemental Products
Reviews

Human CXCR4 (NP_003458) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

You must select a language.

x

Background: CXCR4

CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.

Long Name
C-X-C Motif Chemokine Receptor 4
Entrez Gene IDs
7852 (Human); 12767 (Mouse); 60628 (Rat); 483900 (Canine); 493676 (Feline)
Alternate Names
CD184; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C motif), receptor 4 (fusin); C-X-C chemokine receptor type 4; CXCR4; CXC-R4; CXCR-4; D2S201E; D2S201ESDF-1 receptor; FB22; Fusin; HM89; HM89NPYRL; HSY3RR; LAP3; LAP-3; LCR1; LESTR; LESTRCD184 antigen; Leukocyte-derived seven transmembrane domain receptor; leukocyte-derived seven-transmembrane-domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; NPY3R; NPY3RWHIM; NPYR; NPYRL; NPYY3R; pCXCR4; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; Stromal cell-derived factor 1 receptor; WHIMS

FAQs

No product specific FAQs exist for this product, however you may

View all cDNA Clone FAQs
Loading...

Reviews for Human CXCR4 (NP_003458) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human CXCR4 (NP_003458) VersaClone cDNA and earn rewards!

Have you used Human CXCR4 (NP_003458) VersaClone cDNA?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review