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Human CXCR3 Antibody

Catalog #: MAB160
71 Citations 2 Reviews Datasheet / COA / SDS
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MAB160-100
MAB160-SP
MAB160-500
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Detection of CXCR3 in Human PBMC Lymphocytes by Flow Cytometry.
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Citations (71)
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Human CXCR3 Antibody Summary

Species Reactivity
Human
Specificity
Detects human CXCR3.
Source
Monoclonal Mouse IgG1 Clone # 49801
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human CXCR3
Met1-Leu368
Accession # P49682
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25 µg/106 cells
See below
Immunohistochemistry
8-25 µg/mL
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Neutralization
Measured by its ability to neutralize CXCL11/I‑TAC-induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CXCR3. The Neutralization Dose (ND50) is typically 0.3-1.5 µg/mL in the presence of 7 ng/mL Recombinant Human CXCL11/I‑TAC.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CXCR3 antibody in Human PBMC Lymphocytes antibody by Flow Cytometry. View Larger

Detection of CXCR3 in Human PBMC Lymphocytes by Flow Cytometry. Human PBMC lymphocytes were stained with (A) Mouse Anti-Human CXCR3 Monoclonal Antibody (Catalog # MAB160) or (B) Mouse IgG1 isotype control antibody (MAB002) followed by PE-conjugated anti-Mouse IgG Secondary Antibody (F0102B) and Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody (FAB100A).View our protocol for Staining Membrane-associated Proteins.

Flow Cytometry Detection of CXCR3 antibody in HEK293 Human Cell Line Transfected with human CXCR3 and eGFP antibody by Flow Cytometry. View Larger

Detection of CXCR3 in HEK293 Human Cell Line Transfected with human CXCR3 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human CXCR3 or (B) irrelevant transfectants and eGFP was stained with and either Mouse Anti-Human CXCR3 Monoclonal Antibody (Catalog # MAB160) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (F0101B). Quadrant markers were set based on Mouse IgG1 Flow Cytometry Isotype Control (MAB002). View our protocol for Staining Membrane-associated Proteins.

Immunohistochemistry CXCR3 antibody in Human Tonsil by Immunohistochemistry (IHC-P). View Larger

CXCR3 in Human Tonsil. CXCR3 was detected in immersion fixed paraffin-embedded sections of human tonsil using Human CXCR3 Monoclonal Antibody (Catalog # MAB160) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; CTS002) and counter-stained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Neutralization Chemotaxis Induced by CXCL11/I‑TAC and Neutralization by Human CXCR3 Antibody. View Larger

Chemotaxis Induced by CXCL11/I‑TAC and Neutralization by Human CXCR3 Antibody. Recombinant Human CXCL11/I-TAC (672-IT) chemoattracts the BaF3 mouse pro-B cell line transfected with human CXCR3 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (AR002). Chemotaxis elicited by Recombinant Human CXCL11/I-TAC (7 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human CXCR3 Monoclonal Antibody (Catalog # MAB160). The ND50 is typically 0.3-1.5 µg/mL.

Western Blot Detection of Human CXCR3 by Western Blot View Larger

Detection of Human CXCR3 by Western Blot Functional effects of IP-10 on PCCs(A) Expression of CXCR3 in PCCs, PSCs and HEK293-EBNA/CXCR3-B analyzed by Western Blot. alpha -tubulin was used as loading control. (B) Microphotographs of PCCs migrated through the Boyden chamber in response to 0.5% FBS or IP-10 (24 hr). (C-D) Viability of PCCs after IP-10 addition determined using the MTT assay. Low/high refers to cell seeding density. Data are representative of two/three independent experiments. Data in the histograms are presented as mean ± SD. Image collected and cropped by CiteAb from the following publication (https://www.oncotarget.com/lookup/doi/10.18632/oncotarget.2519), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Human CXCR3 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Human CXCR3 by Immunocytochemistry/Immunofluorescence Infiltration of CXCR3+ cells in the lamina propria of small intestine mucosa.a. Confocal immunofluorescence for CXCR3 was performed in sections of duodenal biopsies from controls (i), untreated celiac patients (ii), and treated celiac patients (iii). CXCR3 is shown in green, and nuclei are shown in red. Untreated celiac patients showed a higher number of positive cells infiltrating the LP. (Magnification, 630×). b. The number of CXCR3+ cells in the LP was higher in the duodenal mucosa of untreated celiac patients (n = 9) compared with control individuals (n = 6) and treated patients (n = 5) (unpaired t-test; p = 0.0089 and p = 0.0055, respectively). The positive cells in LP regions from sections of duodenal biopsies were counted using immunofluorescence microscopy. c. Representative flow cytometric analysis from the LP compartment of a duodenal sample of an untreated CD patient showing plasma cells (CD138+) that express CXCR3. d. Representative flow cytometric analysis from the LP compartment of a duodenal sample of an untreated CD patient showing LP lymphocytes (CD3+ or CD4+) that express CXCR3. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0089068), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CXCR3

CXCR3 is a G protein-coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10), and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells, and NK cells.

Entrez Gene IDs
2833 (Human); 12766 (Mouse); 84475 (Rat)
Alternate Names
CD183 antigen; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; CKR-L2IP-10 receptor; CMKAR3; C-X-C chemokine receptor type 3; CXCR3; CXC-R3; CXCR-3; G protein-coupled receptor 9CD182; GPR9; GPR9Mig-R; Interferon-inducible protein 10 receptor; IP10 receptor; IP10-R; Mig receptor; MigR

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Citations for Human CXCR3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

71 Citations: Showing 1 - 10
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  1. Epithelium-innate immune cell axis in mucosal responses to SIV
    Authors: Shang L, Duan L, Perkey KE et al.
    Mucosal Immunol
  2. M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer
    Authors: Garrido-Martin EM, Mellows TWP, Clarke J et al.
    J Immunother Cancer
  3. Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome.
    Authors: Wightman S, Uppal A, Pitroda S, Ganai S, Burnette B, Stack M, Oshima G, Khan S, Huang X, Posner M, Weichselbaum R, Khodarev N
    Br J Cancer, 2015-06-04;113(2):327-35.
  4. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
    Authors: Denarda Dangaj, Marine Bruand, Alizée J. Grimm, Catherine Ronet, David Barras, Priyanka A. Duttagupta et al.
    Cancer Cell
  5. CXCL4-RNA Complexes Circulate in Systemic Sclerosis and Amplify Inflammatory/Pro-Fibrotic Responses by Myeloid Dendritic Cells
    Authors: I Pietrafort, A Butera, L Gaddini, A Mennella, R Palazzo, D Campanile, K Stefananto, V Riccieri, R Lande, L Frasca
    International Journal of Molecular Sciences, 2022-12-30;24(1):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Stimulation
  6. Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells
    Authors: DM Kaczor, R Kramann, TM Hackeng, LJ Schurgers, RR Koenen
    International Journal of Molecular Sciences, 2022-01-06;23(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  7. Combination of IDO1high and CCL19low expression in the tumor tissue reduces survival in HPV positive cervical cancer
    Authors: H Jayakumar, A Seetharama, S Sunder Sin, H Dhandapani, J Subramani, S Ganeshraja, R Thangaraja, P Ramanathan
    Journal of reproductive immunology, 2021-11-23;149(0):103454.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  8. Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells
    Authors: A Dickhout, DM Kaczor, ACA Heinzmann, SLN Brouns, JWM Heemskerk, MAMJ van Zandvo, RR Koenen
    International Journal of Molecular Sciences, 2021-07-08;22(14):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  9. Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma
    Authors: Jiaqing Yi, Xuanming Shi, Zhenyu Xuan, Jiang Wu
    Cancer Letters
  10. CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma
    Authors: Andrew Cannon, Christopher M. Thompson, H. Carlo Maurer, Pranita Atri, Rakesh Bhatia, Sean West et al.
    Clinical Cancer Research
  11. Role of Chemokine (C-X-C Motif) Ligand 10 (CXCL10) in Renal Diseases
    Authors: J Gao, L Wu, S Wang, X Chen
    Mediators Inflamm., 2020-02-05;2020(0):6194864.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  12. The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3)
    Authors: F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli
    Int J Mol Sci, 2019-10-24;20(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  13. CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-? production in systemic sclerosis
    Authors: R Lande, EY Lee, R Palazzo, B Marinari, I Pietrafort, GS Santos, Y Mattenberg, F Spadaro, K Stefananto, N Iannace, AM Dufour, M Falchi, M Bianco, E Botti, L Bianchi, M Alvarez, V Riccieri, ME Truchetet, G C L Wong, C Chizzolini, L Frasca
    Nat Commun, 2019-05-01;10(1):1731.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  14. Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4
    Authors: Mudan Zhang, Xu Deng, Xinmeng Guan, Lanlan Geng, Ming Fu, Binman Zhang et al.
    Frontiers in Immunology
  15. Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis
    Authors: I Maricic, I Marrero, A Eguchi, R Nakamura, CD Johnson, S Dasgupta, CD Hernandez, PS Nguyen, AD Swafford, R Knight, AE Feldstein, R Loomba, V Kumar
    J. Immunol., 2018-10-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  16. CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration
    Authors: JM Fox, F Kausar, A Day, M Osborne, K Hussain, A Mueller, J Lin, T Tsuchiya, S Kanegasaki, JE Pease
    Sci Rep, 2018-06-21;8(1):9466.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  17. Phase I clinical trial of adoptive transfer of expanded natural killer cells in combination with IgG1 antibody in patients with gastric or colorectal cancer
    Authors: T Ishikawa, T Okayama, N Sakamoto, M Ideno, K Oka, T Enoki, J Mineno, N Yoshida, K Katada, K Kamada, K Uchiyama, O Handa, T Takagi, H Konishi, S Kokura, K Uno, Y Naito, Y Itoh
    Int. J. Cancer, 2018-02-14;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  18. Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages
    Authors: F Bellora, A Dondero, MV Corrias, B Casu, S Regis, F Caliendo, A Moretta, M Cazzola, C Elena, L Vinti, F Locatelli, C Bottino, R Castriconi
    J. Immunol., 2017-07-12;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  19. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
    Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
    Nat Commun, 2017-05-25;8(0):15380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  20. CXCR3 mediates ascites-directed tumor cell migration and predicts poor outcome in ovarian cancer patients
    Authors: C Windmüller, D Zech, S Avril, M Boxberg, T Dawidek, B Schmalfeld, M Schmitt, M Kiechle, H Bronger
    Oncogenesis, 2017-05-15;6(5):e331.
    Species: Human
    Sample Types: Tissue Homogenates, Whole Cells
    Applications: Neutralization, Western Blot
  21. Elevated circulating levels of the interferon-?-induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still's disease
    Authors: JH Han, CH Suh, JY Jung, MH Ahn, MH Han, JE Kwon, H Yim, HA Kim
    Sci Rep, 2017-04-24;7(0):46652.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  22. Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells
    Authors: H Bronger, A Karge, T Dreyer, D Zech, S Kraeft, S Avril, M Kiechle, M Schmitt
    Oncol Lett, 2017-04-05;13(6):4224-4230.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  23. Skewing towards Treg and Th2 responses is a characteristic feature of sustained remission in ANCA-positive granulomatosis with polyangiitis
    Authors: W Szczeklik, B Jakie?a, K Wawrzycka-, M Sanak, M Hubalewska, A Padjas, M Surmiak, K Szczeklik, J Sznajd, J Musia?
    Eur. J. Immunol, 2017-02-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  24. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
    Authors: Valentina Cecchinato
    J. Immunol, 2016-11-28;0(0):.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Tissue
    Applications: IHC-P
  25. TNF-? augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma
    Authors: Kuang-Hui Sun
    J Cell Mol Med, 2016-06-14;0(0):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC-P, Western Blot
  26. CXCR3 Requirement for the Interleukin-13–Mediated Up-Regulation of Interleukin-13R alpha 2 in Pulmonary Fibroblasts
    Authors: Jennifer C. Barnes, Robert V. Lumsden, Julie Worrell, Ian P. Counihan, Sarah L. O’Beirne, John A. Belperio et al.
    American Journal of Respiratory Cell and Molecular Biology
  27. CXCR3 Polymorphism and Expression Associate with Spontaneous Preterm Birth.
    Authors: Karjalainen M, Ojaniemi M, Haapalainen A, Mahlman M, Salminen A, Huusko J, Maatta T, Kaukola T, Anttonen J, Ulvila J, Haataja R, Teramo K, Kingsmore S, Palotie A, Muglia L, Ramet M, Hallman M
    J Immunol, 2015-07-24;195(5):2187-98.
    Species: Human
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC-P, Western Blot
  28. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells.
    Authors: McCully M, Collins P, Hughes T, Thomas C, Billen J, O'Donnell V, Moser B
    J Immunol, 2015-05-22;195(1):96-104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  29. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes
    Authors: Byung Min Chung, Artem Arutyunov, Erika Ilagan, Nu Yao, Marsha Wills-Karp, Pierre A. Coulombe
    Journal of Cell Biology
  30. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy.
    Authors: Zsiros E, Duttagupta P, Dangaj D, Li H, Frank R, Garrabrant T, Hagemann I, Levine B, June C, Zhang L, Wang E, Marincola F, Bedognetti D, Powell D, Tanyi J, Feldman M, Kandalaft L, Coukos G
    Clin Cancer Res, 2015-02-23;21(12):2840-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  31. Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1
    Authors: Julie A Douthwaite, Sudharsan Sridharan, Catherine Huntington, Jayne Hammersley, Rose Marwood, Jonna K Hakulinen et al.
    mAbs
  32. IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival
    Authors: Serena Lunardi, Nigel B. Jamieson, Su Yin Lim, Kristin L. Griffiths, Manuela Carvalho-Gaspar, Osama Al-Assar et al.
    Oncotarget
  33. Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration.
    Authors: Falk M, Singh A, Faber C, Nissen M, Hviid T, Sorensen T
    Invest Ophthalmol Vis Sci, 2014-05-08;55(7):4050-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  34. Inflammatory Cell Distribution in Primary Merkel Cell Carcinoma
    Authors: Rachel Wheat, Claudia Roberts, Tim Waterboer, Jane Steele, Jerry Marsden, Neil M. Steven et al.
    Cancers (Basel)
  35. CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph.
    Authors: Carrega, Paolo, Bonaccorsi, Irene, Di Carlo, Emma, Morandi, Barbara, Paul, Petra, Rizzello, Valeria, Cipollone, Giuseppe, Navarra, Giuseppe, Mingari, Maria Cr, Moretta, Lorenzo, Ferlazzo, Guido
    J Immunol, 2014-03-19;192(8):3805-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  36. Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation.
    Authors: Pinto S, Martinez-Romero A, O'Connor J, Gil-Benso R, San-Miguel T, Terradez L, Monteagudo C, Callaghan R
    BMC Cancer, 2014-02-22;14(0):118.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  37. Role of CXCR3/CXCL10 axis in immune cell recruitment into the small intestine in celiac disease.
    Authors: Bondar C, Araya R, Guzman L, Rua E, Chopita N, Chirdo F
    PLoS ONE, 2014-02-20;9(2):e89068.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  38. Neuroblastoma-derived TGF-beta1 modulates the chemokine receptor repertoire of human resting NK cells.
    Authors: Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, Corrias M, Moretta A, Bottino C
    J Immunol, 2013-04-10;190(10):5321-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  39. Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer.
    Authors: Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, Takeda K, Yamamoto M
    Clin Cancer Res, 2013-03-11;19(8):2224-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  40. Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR
    Authors: J Vinet, M van Zwam, I M Dijkstra, N Brouwer, H R J van Weering, A Watts et al.
    British Journal of Pharmacology
  41. Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo
    Authors: Grant R Stenton, Lloyd F Mackenzie, Patrick Tam, Jennifer L Cross, Curtis Harwig, Jeffrey Raymond et al.
    British Journal of Pharmacology
  42. Human trophectoderm apposition is regulated by interferon gamma-induced protein 10 (IP-10) during early implantation.
    Authors: Sela H, Goldman-Wohl D, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S
    Placenta, 2013-01-08;34(3):222-30.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  43. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis.
    Authors: Chaturvedi, Pallavi, Gilkes, Daniele, Wong, Carmen C, Luo, Weibo, Zhang, Huafeng, Wei, Hong, Takano, Naoharu, Schito, Luana, Levchenko, Andre, Semenza, Gregg L
    J Clin Invest, 2012-12-17;123(1):189-205.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  44. Cigarette Smoke–Induced CXCR3 Receptor Up-Regulation Mediates Endothelial Apoptosis
    Authors: Linden A. Green, Daniela Petrusca, Gangaraju Rajashekhar, Tom Gianaris, Kelly S. Schweitzer, Liang Wang et al.
    American Journal of Respiratory Cell and Molecular Biology
  45. Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3
    Authors: D J Scholten, M Canals, M Wijtmans, S de Munnik, P Nguyen, D Verzijl et al.
    British Journal of Pharmacology
  46. Ubiquitination of CXCR7 controls receptor trafficking.
    Authors: Canals M, Scholten DJ, de Munnik S, Han MK, Smit MJ, Leurs R
    PLoS ONE, 2012-03-23;7(3):e34192.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion.
    Authors: Wu Q, Dhir R, Wells A
    Mol. Cancer, 2012-01-11;11(0):3.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  48. Identification of human NK17/NK1 cells.
    Authors: Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA
    PLoS ONE, 2011-10-21;6(10):e26780.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  49. Immune Response to Mycobacterium tuberculosis Infection in the Parietal Pleura of Patients with Tuberculous Pleurisy
    Authors: Gaetano Caramori, Lisa Lasagna, Angelo G. Casalini, Ian M. Adcock, Paolo Casolari, Marco Contoli et al.
    PLoS ONE
  50. Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention.
    Authors: Franciszkiewicz K, Le Floc'h A, Jalil A, Vigant F, Robert T, Vergnon I, Mackiewicz A, Benihoud K, Validire P, Chouaib S, Combadiere C, Mami-Chouaib F
    Cancer Res., 2009-07-28;69(15):6249-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  51. CXCR3 ligands are augmented during the pathogenesis of pulmonary sarcoidosis.
    Authors: Busuttil A, Weigt SS, Keane MP, Xue YY, Palchevskiy V, Burdick MD, Huang C, Zisman DA, Fishbein M, Lynch JP, Strieter RM, Elashoff RM, Belperio JA
    Eur. Respir. J., 2009-04-22;34(3):676-86.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  52. CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy.
    Authors: Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C
    FASEB J., 2009-04-20;23(9):2928-41.
    Species: Feline, Human
    Sample Types: Tissue Homogenates
    Applications: Functional Assay, Western Blot
  53. Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease.
    Authors: Kim MJ, Romero R, Kim CJ, Tarca AL, Chhauy S, LaJeunesse C, Lee DC, Draghici S, Gotsch F, Kusanovic JP, Hassan SS, Kim JS
    J. Immunol., 2009-03-15;182(6):3919-27.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  54. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
    Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
    J. Immunol., 2008-12-01;181(11):8053-67.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, ICC, IHC-P, Neutralization
  55. The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor.
    Authors: Meiser A, Mueller A, Wise EL, McDonagh EM, Petit SJ, Saran N, Clark PC, Williams TJ, Pease JE
    J. Immunol., 2008-05-15;180(10):6713-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  56. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients.
    Authors: Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D
    J. Immunol., 2007-09-15;179(6):4272-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  57. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells.
    Authors: Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH
    J. Immunol., 2007-09-15;179(6):3724-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  58. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
    Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
    Clin. Immunol., 2006-06-16;120(2):220-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  59. Chemokine receptor expression in rat adjuvant-induced arthritis.
    Authors: Haas CS, Martinez RJ, Attia N, Haines GK, Campbell PL, Koch AE
    Arthritis Rheum., 2005-12-01;52(12):3718-30.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  60. Establishment and characterization of SRIK-NKL: a novel CD8+ natural killer/T cell line derived from a patient with leukemic phase of acute lymphoblastic lymphoma.
    Authors: Srivastava BI, Srivastava MD
    Leuk. Res., 2005-07-01;29(7):771-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  61. Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.
    Authors: Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B
    Arthritis Rheum., 2005-05-01;52(5):1504-16.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  62. Increased expression of CXCR3 and CCR5 on memory CD4+ T-cells migrating into the cerebrospinal fluid of patients with neuroborreliosis: the role of CXCL10 and CXCL11.
    Authors: Lepej SZ, Rode OD, Jeren T, Vince A, Remenar A, Barsic B
    J. Neuroimmunol., 2005-04-19;163(1):128-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  63. Up-regulation of the interferon gamma (IFN-gamma)-inducible chemokines IFN-inducible T-cell alpha chemoattractant and monokine induced by IFN-gamma and of their receptor CXC receptor 3 in human renal cell carcinoma.
    Authors: Suyama T, Furuya M, Nishiyama M, Kasuya Y, Kimura S, Ichikawa T, Ueda T, Nikaido T, Ito H, Ishikura H
    Cancer, 2005-01-15;103(2):258-67.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  64. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses.
    Authors: Lim HW, Hillsamer P, Kim CH
    J. Clin. Invest., 2004-12-01;114(11):1640-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  65. Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10.
    Authors: van Marle G, Henry S, Todoruk T, Sullivan A, Silva C, Rourke SB, Holden J, McArthur JC, Gill MJ, Power C
    Virology, 2004-11-24;329(2):302-18.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC-P
  66. Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis.
    Authors: Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M
    Int. J. Oncol., 2004-09-01;25(3):605-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  67. Expression of functional CCR and CXCR chemokine receptors in podocytes.
    Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
    J. Immunol., 2002-06-15;168(12):6244-52.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  68. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire.
    Authors: Campbell J, Qin S, Unutmaz D, Soler D, Murphy K, Hodge M, Wu L, Butcher E
    J Immunol, 2001-06-01;166(11):6477-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  69. Clonal Th2 cells associated with chronic hypereosinophilia: TARC-induced CCR4 down-regulation in vivo.
    Authors: de Lavareille A, Roufosse F, Schandene L, Stordeur P, Cogan E, Goldman M
    Eur. J. Immunol., 2001-04-01;31(4):1037-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  70. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
    Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
    J. Immunol., 2010-02-17;184(6):2886-98.
  71. Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?
    Authors: S Urra, MC Fischer, JR Martínez, L Véliz, P Orellana, A Solar, K Bohmwald, A Kalergis, C Riedel, AH Corvalán, JC Roa, R Fuentealba, CJ Cáceres, M López-Last, A León, N Droppelman, HE González
    Oncotarget, 2017-12-20;9(2):2445-2467.

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Human CXCR3 Antibody
By Anonymous on 01/24/2021
Application: Flow Sample Tested: Peripheral blood mononuclear cells (PBMCs) Species: Human
Flow Cytometry Human CXCR3 Antibody MAB160
Human CXCR3 Antibody
By Anonymous on 11/15/2018
Application: Flow Sample Tested: J45.01 human acute lymphoblastic leukemia T lymphocyte cell line Species: Human
Flow Cytometry Human CXCR3 Antibody MAB160