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Human CXCR2/IL-8RB Antibody

Catalog #: MAB331
66 Citations 4 Reviews Datasheet / COA / SDS
Clone 48311 was used by HLDA to establish CD designation
Catalog # Availability Size / Price Qty
MAB331-100
MAB331-SP
MAB331-500
Detection of CXCR2/IL‑8 RB in Human Blood Granulocytes by Flow Cytometry.
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Product Details
Citations (66)
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Reviews (4)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CXCR2/IL-8RB Antibody Summary

Species Reactivity
Human
Specificity
Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).
Source
Monoclonal Mouse IgG2A Clone # 48311
Purification
Protein A or G purified from ascites
Immunogen
NS0 mouse myeloma cell line transfected with human CXCR2/IL-8 RB
Met1-Leu355
Accession # AAB25880
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25 µg/106 cells
See below
Immunohistochemistry
8-25 µg/mL
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Neutralization
Measured by its ability to neutralize CXCL1/GRO alpha /KC/CINC‑1-induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CXCR2. The Neutralization Dose (ND50) is typically 1-5 µg/mL in the presence of 5 ng/mL Recombinant Human CXCL1/GRO alpha /KC/CINC‑1.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CXCR2/IL-8 RB antibody in Human Blood Granulocytes antibody by Flow Cytometry. View Larger

Detection of CXCR2/IL‑8 RB in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Monoclonal Antibody (Catalog # MAB331, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).

Immunohistochemistry CXCR2/IL‑8 RB antibody in Human Lymph Node by Immunohistochemistry (IHC-P). View Larger

CXCR2/IL‑8 RB in Human Lymph Node. CXCR2/IL-8 RB was detected in immersion fixed paraffin-embedded sections of human lymph node using 15 µg/mL Mouse Anti-Human CXCR2/IL-8 RB Monoclonal Antibody (Catalog # MAB331) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-AEC Cell & Tissue Staining Kit (red; Catalog # CTS003) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Neutralization Chemotaxis Induced by CXCL1/GRO alpha and Neutralization by Human CXCR2/IL‑8 RB Antibody. View Larger

Chemotaxis Induced by CXCL1/GRO alpha and Neutralization by Human CXCR2/IL‑8 RB Antibody. Recombinant Human CXCL1/GROa (Catalog # 275-GR) chemoattracts the BaF3 mouse pro-B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CXCL1/GROa (5 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human CXCR2/IL-8 RB Monoclonal Antibody (Catalog # MAB331). The ND50 is typically 1-5 µg/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CXCR2/IL-8RB

CXCR2, also known as IL-8 RB, is a G protein-coupled chemokine receptor expressed on neutrophils. It binds IL-8, GRO alpha, GRO beta, GRO gamma, NAP-2, and ENA-78.

Long Name
Interleukin 8 Receptor B
Entrez Gene IDs
3579 (Human); 12765 (Mouse); 29385 (Rat)
Alternate Names
CD182 antigen; CD182; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; CMKAR2; C-X-C chemokine receptor type 2; CXCR2 gene for IL8 receptor type B; CXCR2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8 RB; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; IL8RB; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin-8 receptor type B

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Citations for Human CXCR2/IL-8RB Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

66 Citations: Showing 1 - 10
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  1. Autocrine signaling is a key regulatory element during osteoclastogenesis
    Authors: Paul Kopesky, Kerstin Tiedemann, Dahlia Alkekhia, Christoph Zechner, Bjorn Millard, Birgit Schoeberl et al.
    Biology Open
  2. The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level
    Authors: E Kwon, K Todorova, J Wang, R Horos, KK Lee, VA Neel, GL Negri, PH Sorensen, SW Lee, MW Hentze, A Mandinova
    Nat Commun, 2018-04-30;9(1):1734.
  3. IL8 derived from macrophages inhibits CD8+ T-cell function by downregulating TIM3 expression through IL8-CXCR2 axis in patients with advanced colorectal cancer
    Authors: Zhao, C;Wang, D;Li, Z;Zhang, Z;Xu, Y;Liu, J;Lei, Q;Han, D;Huo, Y;Liu, S;Li, L;Zhang, Y;
    International immunopharmacology
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  4. Interleukin-8 produced from cancer-associated fibroblasts suppresses proliferation of the OCUCh-LM1 cancer cell line
    Authors: R Tanaka, K Kimura, S Eguchi, G Ohira, S Tanaka, R Amano, H Tanaka, M Yashiro, M Ohira, S Kubo
    BMC Cancer, 2022-07-08;22(1):748.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Neutralization, Western Blot
  5. Significance of tumor heterogeneity of p-Smad2 and c-Met in HER2-positive gastric carcinoma with lymph node metastasis
    Authors: G Tsujio, K Maruo, Y Yamamoto, T Sera, A Sugimoto, H Kasashima, Y Miki, M Yoshii, T Tamura, T Toyokawa, H Tanaka, K Muguruma, M Ohira, M Yashiro
    BMC Cancer, 2022-06-01;22(1):598.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  6. CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma
    Authors: Y Yamamoto, A Sugimoto, K Maruo, G Tsujio, T Sera, S Kushiyama, S Nishimura, K Kuroda, S Togano, S Eguchi, R Tanaka, K Kimura, R Amano, M Ohira, M Yashiro
    PLoS ONE, 2022-04-04;17(4):e0266027.
    Species: Human
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  7. Eutopic endometrial immune profile of infertility-patients with and without endometriosis
    Authors: N Freitag, DM Baston-Bue, JS Kruessel, UR Markert, TN Fehm, AP Bielfeld
    Journal of reproductive immunology, 2022-01-29;150(0):103489.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  8. The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes
    Authors: Adrien Guérard, Victor Laurent, Gaëlle Fromont, David Estève, Julia Gilhodes, Edith Bonnelye et al.
    International Journal of Molecular Sciences
  9. Changes in the tumor microenvironment and outcome for TME-targeting therapy in glioblastoma: A pilot study
    Authors: S Ali, TF Borin, R Piranliogl, R Ara, I Lebedyeva, K Angara, BR Achyut, AS Arbab, MH Rashid
    PLoS ONE, 2021-02-05;16(2):e0246646.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  10. Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming
    Authors: AJ Hoogendijk, F Pourfarzad, CEM Aarts, ATJ Tool, IH Hiemstra, L Grassi, M Frontini, AB Meijer, M van den Bi, TW Kuijpers
    Cell Rep, 2019-11-19;29(8):2505-2519.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3)
    Authors: F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli
    Int J Mol Sci, 2019-10-24;20(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  12. Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein
    Authors: Chien-Chiao Huang, Kai-Wen Cheng, Yuan-Chin Hsieh, Wen-Wei Lin, Chiu-Min Cheng, Shyng-Shiou F. Yuan et al.
    Scientific Reports
  13. Development and application of a high-content virion display human GPCR array
    Authors: Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash et al.
    Nature Communications
  14. A Subset of Paracrine Factors as Efficient Biomarkers for Predicting Vascular Regenerative Efficacy of Mesenchymal Stromal/Stem Cells
    Authors: HK Kim, SG Lee, SW Lee, BJ Oh, JH Kim, JA Kim, G Lee, JD Jang, YA Joe
    Stem Cells, 2018-10-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  15. CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy-Resistant Glioblastoma
    Authors: K Angara, TF Borin, MH Rashid, I Lebedyeva, R Ara, PC Lin, A Iskander, RJ Bollag, BR Achyut, AS Arbab
    Neoplasia, 2018-10-01;20(10):1070-1082.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  16. IL-8/CXCR1/2 signalling promotes tumor cell proliferation, invasion and vascular mimicry in glioblastoma
    Authors: I Sharma, A Singh, F Siraj, S Saxena
    J. Biomed. Sci., 2018-08-08;25(1):62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Role of autophagy in the HIV-1 matrix protein p17-driven lymphangiogenesis
    Authors: P Mazzuca, S Marsico, K Schulze, S Mitola, MC Pils, C Giagulli, CA Guzman, A Caruso, F Caccuri
    J. Virol., 2017-07-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  18. Clinicopathologic significance of the CXCL1-CXCR2 axis in the tumor microenvironment of gastric carcinoma
    Authors: H Kasashima, M Yashiro, H Nakamae, G Masuda, H Kinoshita, T Morisaki, T Fukuoka, T Hasegawa, T Nakane, M Hino, K Hirakawa, M Ohira
    PLoS ONE, 2017-06-02;12(6):e0178635.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  19. Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients
    Authors: ALT Loi, S Hoonhorst, C van Aalst, J Langereis, V Kamp, S Sluis-Eisi, N Ten Hacken, JW Lammers, L Koenderman
    Respir. Res., 2017-05-22;18(1):100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  20. Adoptive Transfer of Phosphoantigen-Specific ?? T Cell Subset Attenuates Mycobacterium tuberculosis Infection in Nonhuman Primates
    Authors: A Qaqish, D Huang, CY Chen, Z Zhang, R Wang, S Li, E Yang, Y Lu, MH Larsen, WR Jacobs, L Qian, J Frencher, L Shen, ZW Chen
    J. Immunol., 2017-05-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  21. Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression
    Authors: WW Xu, B Li, XY Guan, SK Chung, Y Wang, YL Yip, SY Law, KT Chan, NP Lee, KW Chan, LY Xu, EM Li, SW Tsao, QY He, AL Cheung
    Nat Commun, 2017-02-10;8(0):14399.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  22. Mycobacteria Manipulate G-Protein-Coupled Receptors to Increase Mucosal Rac1 Expression in the Lungs
    Authors: Nader Alaridah
    J Innate Immun, 2016-12-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  23. Evidence for chemokine synergy during neutrophil migration in ARDS
    Thorax, 2016-08-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  24. TNF-? augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma
    Authors: Kuang-Hui Sun
    J Cell Mol Med, 2016-06-14;0(0):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC-P, Western Blot
  25. Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity
    Authors: Victor Laurent, Adrien Guérard, Catherine Mazerolles, Sophie Le Gonidec, Aurélie Toulet, Laurence Nieto et al.
    Nature Communications
  26. CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma.
    Authors: Li L, Xu L, Yan J, Zhen Z, Ji Y, Liu C, Lau W, Zheng L, Xu J
    J Exp Clin Cancer Res, 2015-10-26;34(0):129.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  27. CXCL1 inhibits airway smooth muscle cell migration through the decoy receptor Duffy antigen receptor for chemokines.
    Authors: Al-Alwan L, Chang Y, Rousseau S, Martin J, Eidelman D, Hamid Q
    J Immunol, 2014-06-30;193(3):1416-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  28. Tumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages.
    Authors: Watari K, Shibata T, Kawahara A, Sata K, Nabeshima H, Shinoda A, Abe H, Azuma K, Murakami Y, Izumi H, Takahashi T, Kage M, Kuwano M, Ono M
    PLoS ONE, 2014-06-12;9(6):e99568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  29. CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph.
    Authors: Carrega, Paolo, Bonaccorsi, Irene, Di Carlo, Emma, Morandi, Barbara, Paul, Petra, Rizzello, Valeria, Cipollone, Giuseppe, Navarra, Giuseppe, Mingari, Maria Cr, Moretta, Lorenzo, Ferlazzo, Guido
    J Immunol, 2014-03-19;192(8):3805-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  30. Simian immunodeficiency virus and human immunodeficiency virus type 1 matrix proteins specify different capabilities to modulate B cell growth.
    Authors: Caccuri, Francesc, Giagulli, Cinzia, Reichelt, Joachim, Martorelli, Debora, Marsico, Stefania, Bugatti, Antonell, Barone, Ines, Rusnati, Marco, Guzman, Carlos A, Dolcetti, Riccardo, Caruso, Arnaldo
    J Virol, 2014-03-12;88(10):5706-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  31. CXCL1/CXCL8 (GROalpha/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro.
    Authors: Omatsu T, Cepinskas G, Clarson C, Patterson E, Alharfi I, Summers K, Couraud P, Romero I, Weksler B, Fraser D
    Am J Physiol Endocrinol Metab, 2014-03-11;306(9):E1077-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  32. The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma.
    Authors: Stofas A, Levidou G, Piperi C, Adamopoulos C, Dalagiorgou G, Bamias A, Karadimou A, Lainakis G, Papadoukakis S, Stravodimos K, Dimopoulos M, Patsouris E, Gakiopoulou H, Korkolopoulou P
    BMC Cancer, 2014-03-04;14(0):149.
    Species: Human
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  33. Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8.
    Authors: Liu L, Xie F, Chang K, Li M, Meng Y, Wang X, Li H, Li D, Yu J
    Int J Clin Exp Pathol, 2014-01-15;7(2):575-83.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  34. Expansion of activated regulatory T cells by myeloid-specific chemokines via an alternative pathway in CSF of bacterial meningitis patients.
    Authors: Shi G, Han J, Liu G, Hao Y, Ma Y, Li T, Wu X, Zhang H, Liu Y, Wang B, Kong Y, Zhou J, Zeng H
    Eur J Immunol, 2013-12-02;44(2):420-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  35. Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche.
    Authors: Infanger, David W, Cho, YouJin, Lopez, Brina S, Mohanan, Sunish, Liu, S Chris, Gursel, Demirkan, Boockvar, John A, Fischbach, Claudia
    Cancer Res, 2013-10-11;73(23):7079-89.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Functional Assay, Western Blot
  36. Interleukin-33 overexpression is associated with gamma-glutamyl transferase in biliary atresia.
    Cytokine, 2012-11-22;61(2):433-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  37. Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells
    Authors: Jhen-Wei Ruan, Yi-Chu Liao, Ingrid Lua, Ming-Hsun Li, Chih-Yi Hsu, Ji-Hshiung Chen
    Breast Cancer Research
  38. Bronchoepithelial Expression of CXCR1 and CXCR2 Does Not Facilitate Transepithelial Migration of Neutrophils
    Authors: Christian Schulz, Benjamin Stoelcker, Brigitte Ruhland, Nico Jentsch, Andreas Steege
    Respiration
  39. Overexpression of the beta subunit of human chorionic gonadotropin promotes the transformation of human ovarian epithelial cells and ovarian tumorigenesis.
    Authors: Guo X, Liu G, Schauer IG, Yang G, Mercado-Uribe I, Yang F, Zhang S, He Y, Liu J
    Am. J. Pathol., 2011-07-18;179(3):1385-93.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  40. Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.
    Authors: Li A, King J, Moro A, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, Strieter RM, Burdick M, Go VL, Reber HA, Eibl G, Hines OJ
    Am. J. Pathol., 2011-03-01;178(3):1340-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  41. CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis.
    Authors: Yang G, Rosen DG, Liu G
    Clin. Cancer Res., 2010-05-26;16(15):3875-86.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  42. IL8 and CXCL13 are potent chemokines for the recruitment of human neural precursor cells across brain endothelial cells.
    Authors: Weiss N, Deboux C, Chaverot N, Miller F, Baron-Van Evercooren A, Couraud P, Cazaubon S
    J Neuroimmunol, 2010-04-18;223(1):131-4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  43. Reduced expression of chemoattractant receptors by polymorphonuclear leukocytes in Hyper IgE Syndrome patients.
    Authors: Mintz R, Garty BZ, Meshel T, Marcus N, Katanov C, Cohen-Hillel E, Ben-Baruch A
    Immunol. Lett., 2009-12-11;130(1):97-106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  44. Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.
    Authors: Reikvam H, Hatfield KJ, Oyan AM, Kalland KH, Kittang AO, Bruserud O
    Eur. J. Haematol., 2009-11-17;84(3):239-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  45. Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis.
    Authors: van der Veen BS, Petersen AH, Belperio JA, Satchell SC, Mathieson PW, Molema G, Heeringa P
    Clin. Exp. Immunol., 2009-10-01;158(1):143-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  46. CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion.
    Authors: Singh S, Nannuru KC, Sadanandam A, Varney ML, Singh RK
    Br. J. Cancer, 2009-04-28;100(10):1638-46.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  47. TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche.
    Authors: Yamamoto M, Kikuchi H, Ohta M, Kawabata T, Hiramatsu Y, Kondo K, Baba M, Kamiya K, Tanaka T, Kitagawa M, Konno H
    Cancer Res., 2008-12-01;68(23):9754-62.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  48. Potential role of high-mobility group box 1 in cystic fibrosis airway disease.
    Authors: Rowe SM, Jackson PL, Liu G, Hardison M, Livraghi A, Solomon GM, McQuaid DB, Noerager BD, Gaggar A, Clancy JP, O'Neal W, Sorscher EJ, Abraham E, Blalock JE
    Am. J. Respir. Crit. Care Med., 2008-07-24;178(8):822-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  49. Expression of CXCL8, CXCR1, and CXCR2 in neurons and glial cells of the human and rabbit retina.
    Authors: Goczalik I, Ulbricht E, Hollborn M, Raap M, Uhlmann S, Weick M, Pannicke T, Wiedemann P, Bringmann A, Reichenbach A, Francke M
    Invest. Ophthalmol. Vis. Sci., 2008-06-14;49(10):4578-89.
    Species: Human, Rabbit
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  50. Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events.
    Authors: Gouwy M, Struyf S, Noppen S, Schutyser E, Springael JY, Parmentier M, Proost P, Van Damme J
    Mol. Pharmacol., 2008-05-09;74(2):485-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  51. A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation.
    Authors: Gaggar A, Jackson PL, Noerager BD, O'Reilly PJ, McQuaid DB, Rowe SM, Clancy JP, Blalock JE
    J. Immunol., 2008-04-15;180(8):5662-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  52. Role of interleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells.
    Authors: Tsai WH, Hsu HC, Lin CC, Ho CK, Kou YR
    Crit. Care Med., 2007-03-01;35(3):879-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  53. Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation.
    Authors: Smith C, Damas JK, Otterdal K, ØIe E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Froland SS, Hansson GK, Aukrust P
    J. Am. Coll. Cardiol., 2006-09-27;48(8):1591-9.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: IHC-Fr, IHC-P, Neutralization
  54. Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression.
    Authors: Kline M, Donovan K, Wellik L, Lust C, Jin W, Moon-Tasson L, Xiong Y, Witzig TE, Kumar S, Rajkumar SV, Lust JA
    Leuk. Res., 2006-08-01;31(5):591-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  55. Chemokine receptor expression in rat adjuvant-induced arthritis.
    Authors: Haas CS, Martinez RJ, Attia N, Haines GK, Campbell PL, Koch AE
    Arthritis Rheum., 2005-12-01;52(12):3718-30.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  56. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
    Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
    J. Immunol., 2005-11-01;175(9):6177-89.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  57. The activation of IL-8 receptors in cultured guinea pig Muller glial cells is modified by signals from retinal pigment epithelium.
    Authors: Malgorzata Goczalik I, Raap M, Weick M, Milenkovic I, Heidmann J, Enzmann V, Wiedemann P, Reichenbach A, Francke M
    J. Neuroimmunol., 2005-04-01;161(1):49-60.
    Species: Guinea Pig
    Sample Types: Whole Cells
    Applications: ICC
  58. Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.
    Authors: Traves SL, Smith SJ, Barnes PJ, Donnelly LE
    J. Leukoc. Biol., 2004-05-20;76(2):441-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  59. Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL.
    Authors: Annels NE, Willemze AJ, van der Velden VH, Faaij CM, van Wering E, Sie-Go DM, Egeler RM, van Tol MJ, Révész T
    Blood, 2003-12-04;103(7):2806-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  60. Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome.
    Authors: Keane MP, Donnelly SC, Belperio JA, Goodman RB, Dy M, Burdick MD, Fishbein MC, Strieter RM
    J. Immunol., 2002-12-01;169(11):6515-21.
    Species: Human
    Sample Types: BALF, Whole Tissue
    Applications: ELISA Development, IHC-P
  61. Expression of functional CCR and CXCR chemokine receptors in podocytes.
    Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
    J. Immunol., 2002-06-15;168(12):6244-52.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  62. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire.
    Authors: Campbell J, Qin S, Unutmaz D, Soler D, Murphy K, Hodge M, Wu L, Butcher E
    J Immunol, 2001-06-01;166(11):6477-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  63. Interleukin 8 Receptor Deficiency Confers Susceptibility to Acute Experimental Pyelonephritis and May Have a Human Counterpart
    Authors: Björn Frendéus, Gabriela Godaly, Long Hang, Diana Karpman, Ann-Charlotte Lundstedt, Catharina Svanborg
    J. Exp. Med
  64. Human Neutrophils Respond to Complement Activation and Inhibition in Microfluidic Devices
    Authors: Sinan Muldur, Douangsone D. Vadysirisack, Sharan Ragunathan, Yalan Tang, Alonso Ricardo, Camil Elie Sayegh et al.
    Frontiers in Immunology
  65. A distinct innate immune signature marks progression from mild to severe COVID-19
    Authors: Stéphane Chevrier, Yves Zurbuchen, Carlo Cervia, Sarah Adamo, Miro E. Raeber, Natalie de Souza et al.
    Cell Reports Medicine
  66. IL-8 mediates idiopathic pulmonary fibrosis mesenchymal progenitor cell fibrogenicity
    Authors: Libang Yang, Jeremy Herrera, Adam Gilbertsen, Hong Xia, Karen Smith, Alexey Benyumov et al.
    American Journal of Physiology-Lung Cellular and Molecular Physiology

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Human CXCR2/IL-8RB Antibody
By Anonymous on 08/05/2021
Application: IHC Sample Tested: Myofibroblasts Species: Human
Human CXCR2/IL-8 RB Antibody
By Michelle Chen on 04/26/2017
Application: B/N Sample Tested: Peripheral blood neutrophils Species: Human
Human CXCR2/IL-8 RB Antibody
By Ruhul Choudhury on 01/23/2017
Application: IHC Sample Tested: fetal membrane Species: Mouse

sodium citrate antigen retrieval

Immunohistochemistry Human CXCR2/IL-8 RB Antibody MAB331
Human CXCR2/IL-8 RB Antibody
By Anonymous on 11/04/2016
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult lung Species: Human
Immunocytochemistry/Immunofluorescence Human CXCR2/IL-8 RB Antibody MAB331