Home / IL-8/CXCL8 / Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Catalog #: DY208
458 Citations 26 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY208
DY208-05
Ancillary Products Available
DY008B: DuoSet ELISA Ancillary Reagent Kit 2
DY999B: Substrate Reagent Pack
DY999: Substrate Reagent Pack
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Human IL-8 / CXCL8 ELISA Standard Curve
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Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Human IL-8/CXCL8 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
31.2 - 2,000 pg/mL
Sufficient Materials
For fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human CXCL8/IL-8. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Block Buffer: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Reagent Diluent: 0.1% BSA, 0.05% Tween 20 in Tris-buffered Saline (20 mM Trizma base, 150 mM NaCI) pH 7.2-7.4, 0.2 μm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

 

Scientific Data

N/A Human IL-8 / CXCL8 ELISA Standard Curve View Larger

Human IL-8 / CXCL8 ELISA Standard Curve

Product Datasheets

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Product Datasheet
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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-8/CXCL8

Interleukin-8 (IL-8), also known as IL-8, GCP-1, and NAP-1, is a heparin-binding 8-9 kDa member of the alpha, or CXC family of chemokines. There are at least 15 human CXC family members that all adopt a three beta -sheet/one alpha -helix structure. Most CXC chemokines show an N-terminal Glu-Leu-Arg (ELR) tripeptide motif. IL-8 circulates as a monomer, homodimer, and heterodimer with CXCL4/PF4. The monomer is considered the most bio-active, while the heterodimer can potentiate PF4 activity. IL-8 oligomerization is modulated by its interactions with matrix and cell surface glycosaminoglycans (GAGs). Mature human IL-8 shares 65-69% amino acid (aa) identity with canine, feline, and porcine IL-8. There is no IL-8 gene counterpart in rodent. 


Multiple isoforms of IL-8 are generated through both alternative splicing and differential proteolytic cleavage. In humans, alternative splicing generates an iso-form with an eleven aa substitution at the C-terminus. Proteolytic processing results in N-terminal truncation of IL-8 and is likely a cell-specific event. For example, fibroblasts and endothelial cells generate the 1-77 form by cleaving IL-8 following Glu21, while monocytes and lymphocytes generate the 6-77 form by cleaving following Leu25. These truncated forms generally show increased bioactivity, particularly through the CXCR1 receptor. IL-8 can also undergo citrullination on Arg27 of the precursor, a modification that increases its half-life and ability to induce leukocytosis. A wide variety of cells secrete IL-8 including monocytes and neutrophils, fibroblasts and keratinocytes, mast cells, visceral smooth muscle cells, dendritic cells, type II great alveolar cells, and endothelial cells. 

IL-8 bioactivity is mediated through two G-protein-coupled receptors, termed CXCR1/IL-8 RA and CXCR2/IL-8 RB. CXCR1 is 45-50 kDa in size and is used almost exclusively by IL-8. CXCR2 is 35-40 kDa in size and is used by nearly all CXC chemokines. Both CXCR1 and CXCR2 constitutively associate into functional homodimers. They can also heterodimerize, but these complexes dissociate following IL-8 binding. CXCR2 responds to low concentrations of IL-8 and is principally associated with chemotaxis and MMP-9 release. CXCR1, in contrast, responds to high concentrations of IL-8 and is associated with respiratory burst and phospholipase D2 activation. Thus, CXCR2 ligation induces leukocyte adhesion to activated vascular endothelium and migration to sites of inflammation, while CXCR1 ligation primes neutrophil antimicrobial activity. IL-8 can also form a complex with Serpin A1/alpha-1 Antitrypsin, and this prevents IL-8 interaction with CXCR1. 

In addition to its pro-inflammatory effects, IL-8 is involved in angiogenesis and the pathogenesis of atherosclerosis and cancer. It induces VEGF expression in vascular endothelial cells and functions as an autocrine factor for EC growth and angiogenesis. It is upregulated in atherosclerotic lesions and is elevated in the serum and cerebrospinal fluid following myocardial infarction. In cancer, IL-8 promotes epithelial-mesenchymal transition as well as tumor cell invasiveness and metastasis.

Long Name:
Interleukin 8
Entrez Gene IDs:
3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
Alternate Names:
3-10C; AMCF-I; C-X-C motif chemokine 8; CXCL8; CXCL8SCYB8; Emoctakin; GCP1; GCP-1TSG-1; IL8; IL-8; interleukin 8; K60; LAI; LECT; LUCT; LYNAP; MDNCF; MDNCFb-ENAP; member 8; MONAP; MONAPGCP1; NAF; NAP1; NAP-1NAP1; NCF; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; TCF; TSG1

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL of Block Buffer to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Human IL-8/CXCL8 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

458 Citations: Showing 1 - 10
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  1. Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa isolates from cystic fibrosis patients
    Authors: Pedersen, BH;Simões, FB;Pogrebnyakov, I;Welch, M;Johansen, HK;Molin, S;La Rosa, R;
    PLoS biology
    Species: Human
    Sample Types: Cell Culture Supernates
  2. Exploring the potency of polyphenol-rich blend from Lonicera caerulea var. Kamtschatica sevast., Aronia melanocarpa, and Echinacea purpurea: Promising anti-inflammatory, antioxidant, and antiviral properties
    Authors: Zima, K;Khaidakov, B;Sochocka, M;Ochnik, M;Lemke, K;Kowalczyk, P;
    Heliyon
    Species: Human
    Sample Types: Cell Culture Supernates
  3. Endoplasmic Reticulum Stress Differently Modulates the Release of IL-6 and IL-8 Cytokines in Human Glial Cells
    Authors: Soko?owska, P;Wiktorowska-Owczarek, A;Tambor, J;Gawlak-Socka, S;Kowalczyk, E;Jó?wiak-B?benista, M;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  4. Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein
    Authors: Caohuy, H;Eidelman, O;Chen, T;Mungunsukh, O;Yang, Q;Walton, NI;Pollard, BS;Khanal, S;Hentschel, S;Florez, C;Herbert, AS;Pollard, HB;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Effect of progestin-based contraceptives on HIV-associated vaginal immune biomarkers and microbiome in adolescent girls
    Authors: Nasr, MA;Aldous, A;Daniels, J;Joy, C;Capozzi, E;Yang, M;Moriarty, P;Emmanuel-Baker, V;Malcolm, S;Green, SJ;Gomez-Lobo, V;Ghosh, M;
    PloS one
    Species: Human
    Sample Types: Vaginal Swab
  6. Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing
    Authors: Reedy, JL;Jensen, KN;Crossen, AJ;Basham, KJ;Ward, RA;Reardon, CM;Brown Harding, H;Hepworth, OW;Simaku, P;Kwaku, GN;Tone, K;Willment, JA;Reid, DM;Stappers, MHT;Brown, GD;Rajagopal, J;Vyas, JM;
    Nature communications
    Species: Human
    Sample Types: Cell Culture Supernates
  7. Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations
    Authors: Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A;
    Nature communications
    Species: Human
    Sample Types: Sputum
  8. Intestinal Epithelial Co-Culture Sensitivity to Pro-Inflammatory Stimuli and Polyphenols Is Medium-Independent
    Authors: Haddad, MJ;Zuluaga-Arango, J;Mathieu, H;Barbezier, N;Anton, PM;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Taxonomic and phenotypic analysis of bifidobacteria isolated from IBD patients as potential probiotic strains
    Authors: Bosselaar, S;Dhelin, L;Dautel, E;Titecat, M;Duthoy, S;Stelmaszczyk, M;Delory, N;De Sousa Violante, M;Machuron, F;Ait-Abderrahim, H;Desreumaux, P;Foligné, B;Monnet, C;
    BMC microbiology
    Species: Human
    Sample Types: Cell Culture Supernates
  10. Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study
    Authors: Seo, DY;Park, JW;Kim, SH;Oh, SR;Han, SB;Kwon, OK;Ahn, KS;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  11. CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling
    Authors: Halasz, H;Malekos, E;Covarrubias, S;Yitiz, S;Montano, C;Sudek, L;Katzman, S;Liu, SJ;Horlbeck, MA;Namvar, L;Weissman, JS;Carpenter, S;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates
    Authors: De, K;Belardinelli, JM;Pandurangan, AP;Ehianeta, T;Lian, E;Pal?eková, Z;Lam, H;Gonzalez-Juarrero, M;Bryant, JM;Blundell, TL;Parkhill, J;Floto, RA;Lowary, TL;Wheat, WH;Jackson, M;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Human
    Sample Types: Cell Culture Supernates
  13. Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes
    Authors: Roos, J;Zinngrebe, J;Huber-Lang, M;Lupu, L;Schmidt, MA;Strobel, H;Westhoff, MA;Stifel, U;Gebhard, F;Wabitsch, M;Mollnes, TE;Debatin, KM;Halbgebauer, R;Fischer-Posovszky, P;
    Cell death & disease
    Species: Human
    Sample Types: Cell Culture Supernates
  14. Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation
    Authors: Marinho, A;Seabra, CL;Lima, SAC;Lobo-da-Cunha, A;Reis, S;Nunes, C;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  15. The proteome of bacterial membrane vesicles in Escherichia coli-a time course comparison study in two different media
    Authors: Yu, MSC;Chiang, DM;Reithmair, M;Meidert, A;Brandes, F;Schelling, G;Ludwig, C;Meng, C;Kirchner, B;Zenner, C;Muller, L;Pfaffl, MW;
    Frontiers in microbiology
    Species: Human
    Sample Types: Cell Culture Supernates
  16. Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
    Authors: Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Human
    Sample Types: Cell Culture Supernates
  17. P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis
    Authors: Li, Z;Barnaby, R;Nymon, A;Roche, C;Koeppen, K;Ashare, A;Hogan, DA;Gerber, SA;Taatjes, DJ;Hampton, TH;Stanton, BA;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: BALF
  18. Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial
    Authors: Vicariotto, F;Malfa, P;Viciani, E;Dell'Atti, F;Squarzanti, DF;Marcante, A;Castagnetti, A;Ponchia, R;Governini, L;De Leo, V;
    Nutrients
    Species: Human
    Sample Types: Vaginal Swab
  19. The clarithromycin-binding proteins NIPSNAP1 and 2 regulate cytokine production through mitochondrial quality control
    Authors: Yamamoto, S;Ogasawara, N;Mitsuhashi, Y;Takano, K;Yokota, SI;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  20. Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air-liquid interface
    Authors: Upadhyay, S;Rahman, M;Rinaldi, S;Koelmel, J;Lin, EZ;Mahesh, PA;Beckers, J;Johanson, G;Pollitt, KJG;Palmberg, L;Irmler, M;Ganguly, K;
    Respiratory research
    Species: Human
    Sample Types: Cell Culture Supernates
  21. ADS024, a single-strain live biotherapeutic product of Bacillus velezensis alleviates dextran sulfate-mediated colitis in mice, protects human colonic epithelial cells against apoptosis, and maintains epithelial barrier function
    Authors: Irwin, S;Chupina Estrada, A;Nelson, B;Bullock, A;Limketkai, B;Ho, W;Acton, S;Chesnel, L;Koon, HW;
    Frontiers in microbiology
    Species: Human
    Sample Types: Cell Culture Supernates
  22. Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis
    Authors: Kim, YT;Huh, JW;Choi, YH;Yoon, HK;Nguyen, TT;Chun, E;Jeong, G;Park, S;Ahn, S;Lee, WK;Noh, YW;Lee, KS;Ahn, HS;Lee, C;Lee, SM;Kim, KS;Suh, GJ;Jeon, K;Kim, S;Jin, M;
    EMBO molecular medicine
    Species: Mouse
    Sample Types: Plasma, Peritoneal Lavage Fluid
  23. High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification
    Authors: Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A;
    Biomolecules
    Species: Human
    Sample Types: Cell Culture Supernates
  24. Evaluation of high dose N- Acetylcysteine on airway inflammation and quality of life outcomes in adults with bronchiectasis: A randomised placebo-controlled pilot study
    Authors: Jayaram, L;King, PT;Hunt, J;Lim, M;Park, C;Hu, E;Dousha, L;Ha, P;Bartlett, JB;Southcott, AM;Muruganandan, S;Vogrin, S;Rees, MA;Dean, OM;Wong, CA;
    Pulmonary pharmacology & therapeutics
    Species: Human
    Sample Types: Sputum
  25. The Protective Role of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Protein Sigma-1 Receptor in Regulating Endothelial Inflammation and Permeability Associated with Acute Lung Injury
    Authors: Mahamed, Z;Shadab, M;Najar, RA;Millar, MW;Bal, J;Pressley, T;Fazal, F;
    Cells
    Species: Human
    Sample Types: Cell Culture Supernates
  26. ?-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling
    Authors: Kim, HS;Kim, HJ;Hong, YD;Son, ED;Cho, SY;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  27. Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin
    Authors: Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG;
    Cells
    Species: Human
    Sample Types: Cell Culture Supernates
  28. Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity
    Authors: Nikiforov, NG;Kirichenko, TV;Kubekina, MV;Chegodaev, YS;Zhuravlev, AD;Ilchuk, LA;Nikolaeva, MA;Arefieva, AS;Popov, MA;Verkhova, SS;Bagheri Ekta, M;Orekhov, AN;
    Cytokine
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Design and Fabrication of a 3D-Printed Microfluidic Immunoarray for Ultrasensitive Multiplexed Protein Detection
    Authors: Hiniduma, K;Bhalerao, KS;De Silva, PIT;Chen, T;Rusling, JF;
    Micromachines
    Species: Human
    Sample Types: Protein, Serum
  30. The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi
    Authors: Obolski, U;Swarthout, TD;Kalizang'oma, A;Mwalukomo, TS;Chan, JM;Weight, CM;Brown, C;Cave, R;Cornick, J;Kamng'ona, AW;Msefula, J;Ercoli, G;Brown, JS;Lourenço, J;Maiden, MC;French, N;Gupta, S;Heyderman, RS;
    Nature communications
    Species: Human
    Sample Types: Cell Culture Supernates
  31. A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection
    Authors: Cholon, DM;Greenwald, MA;Higgs, MG;Quinney, NL;Boyles, SE;Meinig, SL;Minges, JT;Chaubal, A;Tarran, R;Ribeiro, CMP;Wolfgang, MC;Gentzsch, M;
    Cells
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Formoterol Exerts Anti-Cancer Effects Modulating Oxidative Stress and Epithelial-Mesenchymal Transition Processes in Cigarette Smoke Extract Exposed Lung Adenocarcinoma Cells
    Authors: Ferraro, M;Di Vincenzo, S;Lazzara, V;Pinto, P;Patella, B;Inguanta, R;Bruno, A;Pace, E;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  33. Mesenchymal stem cell-derived secretomes-enriched alginate/ extracellular matrix hydrogel patch accelerates skin wound healing
    Authors: Kwon, JW;Savitri, C;An, B;Yang, SW;Park, K;
    Biomaterials research
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression
    Authors: Zobel, CM;Wenzel, W;Krüger, JP;Baumgarten, U;Wagelöhner, T;Neumann, N;Foroutan, B;Müller, R;Müller, A;Rauschning, D;Schü beta ler, M;Scheit, L;Weinreich, F;Oltmanns, K;Keidel, F;Koch, M;Spethmann, S;Schreiner, M;
    Frontiers in microbiology
    Species: Human
    Sample Types: Serum
  35. Parkin Promotes Airway Inflammatory Response to Interferon Gamma
    Authors: Dimasuay, KG;Schaunaman, N;Berg, B;Nichols, T;Chu, HW;
    Biomedicines
    Species: Human
    Sample Types: Cell Culture Supernates
  36. Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma
    Authors: Dumitru, CA;Schröder, H;Schäfer, FTA;Aust, JF;Kre beta e, N;Siebert, CLR;Stein, KP;Haghikia, A;Wilkens, L;Mawrin, C;Sandalcioglu, IE;
    Cells
    Species: Human
    Sample Types: Cell Culture Supernates
  37. Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health
    Authors: Campesi, I;Capobianco, G;Cano, A;Lodde, V;Cruciani, S;Maioli, M;Sotgiu, G;Idda, ML;Puci, MV;Ruoppolo, M;Costanzo, M;Caterino, M;Cambosu, F;Montella, A;Franconi, F;
    Biomedicines
    Species: Human
    Sample Types: Amniotic Fluid
  38. Genomic, transcriptomic, and phenotypic differences among archetype Shigella flexneri strains of serotypes 2a, 3a, and 6
    Authors: Gabor, CE;Hazen, TH;Delaine-Elias, BC;Rasko, DA;Barry, EM;
    mSphere
    Species: Human
    Sample Types: Cell Culture Supernates
  39. Skin microbiota secretomes modulate cutaneous innate immunity against Borrelia burgdorferi s.s
    Authors: Baquer, F;Jaulhac, B;Barthel, C;Paz, M;Wolfgramm, J;Müller, A;Boulanger, N;Grillon, A;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  40. Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties
    Authors: Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T;
    International immunopharmacology
    Species: Human
    Sample Types: Cell Culture Supernates
  41. Enamel Matrix Derivative Suppresses Chemokine Expression in Oral Epithelial Cells
    Authors: Panahipour, L;Botta, S;Abbasabadi, AO;Afradi, Z;Gruber, R;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  42. TNF-? and Poly(I:C) induction of A20 and activation of NF-?B signaling are independent of ABCF1 in human airway epithelial cells
    Authors: Cao, QT;Ishak, M;Shpilman, I;Hirota, JA;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  43. Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins
    Authors: Williams, MR;Bagood, MD;Enroth, TJ;Bunch, ZL;Jiang, N;Liu, E;Almoughrabie, S;Khalil, S;Li, F;Brinton, S;Cech, NB;Horswill, AR;Gallo, RL;
    Cell reports
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
    Authors: Shen, CJ;Chan, RH;Lin, BW;Li, NC;Huang, YH;Chang, WC;Chen, BK;
    Theranostics
    Species: Human
    Sample Types: Cell Culture Supernates
  45. Helicobacter pylori Infection in Infant Rhesus Macaque Monkeys is Associated with an Altered Lung and Oral Microbiome
    Authors: Siegel, NA;Jimenez, MT;Rocha, CS;Rolston, M;Dandekar, S;Solnick, JV;Miller, LA;
    Research square
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: BALF, Plasma
  46. Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions
    Authors: Faria, J;Ahmed, S;Stamatialis, D;Verhaar, MC;Masereeuw, R;Gerritsen, KGF;Mih?il?, SM;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  47. Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin
    Authors: Leignadier, J;Drago, M;Lesouhaitier, O;Barreau, M;Dashi, A;Worsley, O;Attia-Vigneau, J;
    Pharmaceutics
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Synergy and oxygen adaptation for development of next-generation probiotics
    Authors: Khan, MT;Dwibedi, C;Sundh, D;Pradhan, M;Kraft, JD;Caesar, R;Tremaroli, V;Lorentzon, M;Bäckhed, F;
    Nature
    Species: Human
    Sample Types: Cell Culture Supernates
  49. Supersulphides provide airway protection in viral and chronic lung diseases
    Authors: Matsunaga, T;Sano, H;Takita, K;Morita, M;Yamanaka, S;Ichikawa, T;Numakura, T;Ida, T;Jung, M;Ogata, S;Yoon, S;Fujino, N;Kyogoku, Y;Sasaki, Y;Koarai, A;Tamada, T;Toyama, A;Nakabayashi, T;Kageyama, L;Kyuwa, S;Inaba, K;Watanabe, S;Nagy, P;Sawa, T;Oshiumi, H;Ichinose, M;Yamada, M;Sugiura, H;Wei, FY;Motohashi, H;Akaike, T;
    Nature communications
    Species: Human
    Sample Types: Cell Culture Supernates
  50. Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells
    Authors: Zhou, L;Fang, L;Tamm, M;Stolz, D;Roth, M;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  51. Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells
    Authors: Kalsi, KK;Jackson, S;Baines, DL;
    PloS one
    Species:  Human
    Sample Types: Cell Culture Supernates
  52. Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease
    Authors: Fiorillo, A;Gallego, JJ;Casanova-Ferrer, F;Giménez-Garzó, C;Urios, A;Ballester, MP;Durbán, L;Rios, MP;Megías, J;San Miguel, T;Kosenko, E;Escudero-García, D;Benlloch, S;Felipo, V;Montoliu, C;
    International journal of molecular sciences
    Species: Human
    Sample Types: Plasma
  53. Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype
    Authors: Warren, KJ;Beck, EM;Callahan, SJ;Helms, MN;Middleton, E;Maddock, S;Carr, JR;Harris, D;Blagev, DP;Lanspa, MJ;Brown, SM;Paine, R;
    Respiratory research
    Species: Human
    Sample Types: BALF
  54. Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-? expression in TNF-?/IFN-?-stimulated human keratinocytes
    Authors: Jeon, KB;Kim, J;Lim, CM;Park, JY;Kim, NY;Lee, J;Oh, DK;Yoon, DY;
    International immunopharmacology
    Species: Human
    Sample Types: Cell Culture Supernates
  55. Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts
    Authors: A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel
    Cell Reports, 2023-04-28;42(5):112453.
    Species: Human
    Sample Types:
  56. Parkin promotes airway inflammatory response to interferon gamma
    Authors: Dimasuay, KG;Berg, B;Schaunaman, N;Nichols, T;Chu, HW;
    Research square
    Species: Human
    Sample Types: Cell Culture Supernates
  57. Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation
    Authors: M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi
    Scientific Reports, 2023-03-21;13(1):4656.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Multi-Species Probiotic Strain Mixture Enhances Intestinal Barrier Function by Regulating Inflammation and Tight Junctions in Lipopolysaccharides Stimulated Caco-2 Cells
    Authors: H Han, Y You, S Cha, TR Kim, M Sohn, J Park
    Microorganisms, 2023-03-03;11(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Glycolipid-enriched fraction of Osmanthus fragrans inhibits LPS-induced expression of inflammatory genes, COX-2, E-selectin, and Interleukin-8
    Authors: T Pirker, EM Pferschy-W, E Bampali, V Bochkov, R Bauer
    Journal of ethnopharmacology, 2023-03-02;0(0):116328.
    Species: Human
    Sample Types: Cell Culture Supenates
  60. Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA
    Authors: AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger
    Scientific Reports, 2023-02-16;13(1):2767.
    Species: Human
    Sample Types: Cell Culture Supernates
  61. Assessment of the mixed origin of the gastric epithelial extracellular vesicles in acellular transfer of Helicobacter pylori toxins and a systematic review
    Authors: S Saberi, M Esmaeili, R Saghiri, F Shekari, M Mohammadi
    Microbial pathogenesis, 2023-02-08;0(0):106024.
    Species: Human
    Sample Types: Cell Culture Supernates
  62. SCCA1/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses
    Authors: L Chen, V Shi, S Wang, R Freeman, F Ruiz, K Jayachandr, J Zhang, P Cosper, L Sun, CJ Luke, C Spina, PW Grigsby, JK Schwarz, S Markovina
    bioRxiv : the preprint server for biology, 2023-02-03;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway
    Authors: D Tortolani, C Di Meo, S Standoli, F Ciaramella, S Kadhim, E Hsu, C Rapino, M Maccarrone
    International Journal of Molecular Sciences, 2023-02-01;24(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Induction of psoriasis- and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix
    Authors: B Morgner, J Tittelbach, C Wiegand
    Scientific Reports, 2023-01-31;13(1):1807.
    Species: Human
    Sample Types: Cell Culture Supernates
  65. The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure
    Authors: D Hinata, R Fukuda, T Okiyoneda
    International Journal of Molecular Sciences, 2023-01-24;24(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  66. Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis
    Authors: M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi
    PLoS ONE, 2023-01-20;18(1):e0280385.
    Species: Human
    Sample Types: Cell Culture Supernates
  67. Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model
    Authors: DT Spiegelbur, M Mannes, A Schultze, F Scheibenbe, F Müller, A Klitzing, DAC Messerer, K Nilsson Ek, B Nilsson, M Huber-Lang, CK Braun
    PLoS ONE, 2023-01-12;18(1):e0280069.
    Species: Human
    Sample Types: Plasma
  68. Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release
    Authors: G Bredeck, M Busch, A Rossi, B Stahlmecke, KW Fomba, H Herrmann, RPF Schins
    Environment international, 2023-01-11;172(0):107732.
    Species: Human
    Sample Types: Cell Culture Supernates
  69. Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
    Authors: TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin
    Cell Reports, 2022-12-30;42(1):111905.
    Species: Human
    Sample Types: Cell Culture Supernates
  70. Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway
    Authors: K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou
    International Journal of Molecular Sciences, 2022-12-23;24(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  71. Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium
    Authors: Q Huang, M Peng, Y Gu, J Wu, Y Zhan, Z Deng, S Chen, R Yang, J Chen, J Xie
    Oxidative Medicine and Cellular Longevity, 2022-12-19;2022(0):7067623.
    Species: Human
    Sample Types: Cell Culture Supernates
  72. Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study
    Authors: LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts
    Cytokine, 2022-12-05;162(0):156102.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study
    Authors: LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues
    Journal of Clinical Medicine, 2022-12-02;11(23):.
    Species: Human
    Sample Types: Plasma
  74. Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition
    Authors: T Luong, E Cukierman
    BMC Cancer, 2022-12-02;22(1):1255.
    Species: Human
    Sample Types: Cell Culture Supernates
  75. KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer
    Authors: J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi
    Cancer Research, 2022-11-15;0(0):OF1-OF14.
    Species: Human
    Sample Types: Cell Culture Supernates
  76. Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model
    Authors: E Fournier, J Ratel, S Denis, M Leveque, P Ruiz, C Mazal, F Amiard, M Edely, V Bezirard, E Gaultier, B Lamas, E Houdeau, E Engel, F Lagarde, L Etienne-Me, M Mercier-Bo, S Blanquet-D
    Journal of Hazardous Materials, 2022-11-11;443(0):130383.
    Species: Human
    Sample Types: Cell Culture Supernates
  77. Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts
    Authors: KEC Blokland, M Nizamoglu, H Habibie, T Borghuis, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess
    Frontiers in Pharmacology, 2022-11-03;13(0):989169.
    Species: Human
    Sample Types: Cell Culture Supernates
  78. In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells
    Authors: B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang
    Cells, 2022-10-28;11(21):.
    Species: Human
    Sample Types: Cell Culture Supernates
  79. Negative Magnetic Sorting Preserves the Functionality of Ex Vivo Cultivated Non-Adherent Human Monocytes
    Authors: M Hornschuh, V Haas, PP Winkel, MY Gökyildiri, CS Mullins, IM Wrobel, C Manteuffel, E Wirthgen
    Biology, 2022-10-27;11(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  80. GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation
    Authors: TY Chu, C Zheng-Géra, KY Huang, YC Chang, YW Chen, KY I, YL Lo, NY Chiang, HY Chen, M Stacey, S Gordon, WY Tseng, CY Sun, YM Wu, YS Pan, CH Huang, CY Lin, TC Chen, K El Omari, M Antonelou, SR Henderson, A Salama, E Seiradake, HH Lin
    Nature Communications, 2022-10-27;13(1):6385.
    Species: Human
    Sample Types: Cell Culture Supernates
  81. Evasion of cGAS and TRIM5 defines pandemic HIV
    Authors: L Zuliani-Al, ML Govasli, J Rasaiyaah, C Monit, SO Perry, RP Sumner, S McAlpine-S, C Dickson, KM Rifat Fays, L Hilditch, RJ Miles, F Bibollet-R, BH Hahn, T Boecking, N Pinotsis, LC James, DA Jacques, GJ Towers
    Nature Microbiology, 2022-10-26;7(11):1762-1776.
    Species: Human
    Sample Types: Cell Culture Supernates
  82. Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation
    Authors: P Marona, J Górka, O Kwapisz, J Jura, J Rys, RM Hoffman, K Miekus
    Cell Death & Disease, 2022-09-22;13(9):814.
    Species: Human, Mouse
    Sample Types: Cell Culture Supernates, Plasma
  83. Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models
    Authors: E Fournier, M Leveque, P Ruiz, J Ratel, C Durif, S Chalancon, F Amiard, M Edely, V Bezirard, E Gaultier, B Lamas, E Houdeau, F Lagarde, E Engel, L Etienne-Me, S Blanquet-D, M Mercier-Bo
    Journal of Hazardous Materials, 2022-09-21;442(0):130010.
    Species: Human
    Sample Types: Cell Culture Supernates
  84. Simultaneous Detection of RIG-1, MDA5, and IFIT-1 Expression Is a Convenient Tool for Evaluation of the Interferon-Mediated Response
    Authors: AA Lozhkov, MA Plotnikova, MA Egorova, IL Baranovska, EA Elpaeva, SA Klotchenko, AV Vasin
    Viruses, 2022-09-21;14(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  85. Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts
    Authors: M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker
    International Journal of Molecular Sciences, 2022-09-08;23(18):.
    Species: Human
    Sample Types: Cell Culture Supernatants
  86. Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection
    Authors: KG Dimasuay, N Schaunaman, B Berg, D Cervantes, E Kruger, FL Heppner, DA Ferrington, HW Chu
    Scientific Reports, 2022-08-25;12(1):14507.
    Species: Human
    Sample Types: Cell Lysates
  87. Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity
    Authors: L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo
    International Journal of Molecular Sciences, 2022-08-22;23(16):.
    Species: Human
    Sample Types: Cell Culture Supernates
  88. Gentle Touch Therapy, Pain Relief and Neuroplasticity at Baseline in Fibromyalgia Syndrome: A Randomized, Multicenter Trial with Six-Month Follow-Up
    Authors: ASI Salgado, MH Takemoto, CFTC de Souza, DC Salm, D da Rosa, GC Cardoso, DD Ludtke, SFC Soares, JK Ferreira, AR Dutra, YC Szeremeta, G Mazzardo, J Mayra, DDL Sheffer, W Caumo, EB Bittencour, R Schleip, A Latini, F Bobinski, DF Martins
    Journal of Clinical Medicine, 2022-08-20;11(16):.
    Species: Human
    Sample Types: Serum
  89. SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity
    Authors: C Amormino, V Tedeschi, G Paldino, S Arcieri, MT Fiorillo, A Paiardini, L Tuosto, M Kunkl
    Cells, 2022-08-15;11(16):.
    Species: Human
    Sample Types: Cell Culture Supernates
  90. Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells
    Authors: M Busch, G Bredeck, F Waag, K Rahimi, H Ramachandr, T Bessel, S Barcikowsk, A Herrmann, A Rossi, RPF Schins
    Biomolecules, 2022-08-09;12(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  91. Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation
    Authors: DC Humphries, R Mills, C Boz, BJ McHugh, N Hirani, AG Rossi, A Pedersen, HT Schambye, RJ Slack, H Leffler, UJ Nilsson, W Wang, T Sethi, AC Mackinnon
    Frontiers in Pharmacology, 2022-08-08;13(0):949264.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  92. Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells
    Authors: JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer
    Scientific Reports, 2022-08-01;12(1):13202.
    Species: Human
    Sample Types: Cell Culture Supernates
  93. The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model
    Authors: EM Smith, CL Grassel, A Papadimas, J Foulke-Abe, EM Barry
    PloS Neglected Tropical Diseases, 2022-07-26;16(7):e0010638.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis
    Authors: S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek
    Journal of ovarian research, 2022-07-26;15(1):87.
    Species: Human
    Sample Types: Cell Culture Supernates
  95. Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems
    Authors: LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt
    Scientific Reports, 2022-07-20;12(1):12448.
    Species: Human
    Sample Types: Cell Culture Supernates
  96. Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1
    Authors: H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd
    Mucosal Immunology, 2022-07-15;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression
    Authors: M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta
    Cancers, 2022-07-13;14(14):.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells
    Authors: K Ueno-Shuto, S Kamei, M Hayashi, A Fukuyama, Y Uchida, N Tokutomi, MA Suico, H Kai, T Shuto
    International Journal of Molecular Sciences, 2022-07-13;23(14):.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. Digested Human Colostrum Reduces Interleukin-8 Production in Induced Human Intestinal Epithelial Cells
    Authors: Y Lyu, Y Chen
    Nutrients, 2022-07-06;14(14):.
    Species: Human
    Sample Types: Cell Culture Supernates
  100. Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds
    Authors: A Moniot, J Braux, R Siboni, C Guillaume, S Audonnet, I Allart-Sim, J Sapi, R Tirouvanzi, S Gérard, SC Gangloff, F Velard
    International Journal of Molecular Sciences, 2022-06-29;23(13):.
    Species: Human
    Sample Types: Cell Culture Supernates
  101. Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models
    Authors: S Upadhyay, A Chakrabort, TA Thimraj, M Baldi, A Steneholm, K Ganguly, P Gerde, L Ernstgård, L Palmberg
    Oncogene, 2022-05-24;10(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  102. Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus
    Authors: JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich
    Cellular Signalling, 2022-05-21;96(0):110360.
    Species: Human
    Sample Types: Plasma
  103. Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease
    Authors: Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng, S Chen, X Wu, Y Lv, Z Zeng, J Xie
    Respiratory Research, 2022-05-12;23(1):120.
    Species: Human
    Sample Types: Cell Culture Supernates
  104. Inhibition of Spleen Tyrosine Kinase Restores Glucocorticoid Sensitivity to Improve Steroid-Resistant Asthma
    Authors: Q Liu, L Hua, C Bao, L Kong, J Hu, C Liu, Z Li, S Xu, X Liu
    Frontiers in Pharmacology, 2022-05-05;13(0):885053.
    Species: Human
    Sample Types: Cell Culture Supernates
  105. IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
    Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
    Cells, 2022-04-30;11(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  106. Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells
    Authors: E Filidou, L Kandilogia, G Tarapatzi, M Spathakis, P Steiropoul, D Mikroulis, K Arvanitidi, V Paspaliari, G Kolios
    International Journal of Molecular Sciences, 2022-04-20;23(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
    Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
    Scientific Reports, 2022-04-11;12(1):5181.
    Species: Human
    Sample Types: Cell Culture Supernates
  108. Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability
    Authors: H Janbazacya, J van Bergen, S Varasteh, J Garssen, G Folkerts, S Braber
    Cytokine, 2022-04-08;154(0):155878.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release
    Authors: M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue
    International Journal of Molecular Sciences, 2022-04-06;23(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  110. Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts
    Authors: S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne
    Pharmaceutics, 2022-03-28;14(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
    Authors: T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber
    Science Advances, 2022-03-23;8(12):eabh4050.
    Species: Human
    Sample Types: Serum
  112. Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence
    Authors: E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser
    Cell Death and Differentiation, 2022-03-09;0(0):.
    Species: Human
    Sample Types: Serum
  113. A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site
    Authors: G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown
    Scientific Reports, 2022-03-07;12(1):3990.
    Species: Human
    Sample Types: Blister Fluid
  114. Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women
    Authors: A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith
    Cells, 2022-03-01;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  115. E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing
    Authors: AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl
    Cells, 2022-02-23;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications
    Authors: OF McElvaney, T Asakura, SL Meinig, JL Torres-Cas, RS Hagan, C Gabillard, MP Murphy, LB Thorne, A Borczuk, EP Reeves, RE Zumwalt, Y Mikami, TP Carroll, K Okuda, G Hogan, OJ McElvaney, J Clarke, NL McEvoy, PW Mallon, C McCarthy, G Curley, MC Wolfgang, RC Boucher, NG McElvaney
    EBioMedicine, 2022-02-22;77(0):103894.
    Species: Human
    Sample Types: Plasma
  117. Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models
    Authors: J Queen, JC Domingue, JR White, C Stevens, B Udayasurya, TTD Nguyen, S Wu, H Ding, H Fan, M McMann, A Corona, TC Larman, SS Verbridge, F Housseau, DJ Slade, JL Drewes, CL Sears
    MBio, 2022-02-08;0(0):e0299121.
    Species: Human
    Sample Types: Cell Culture Supernates
  118. Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length
    Authors: S Hong, KH Park, YE Lee, JE Lee, YM Kim, E Joo, I Cho
    PLoS ONE, 2022-02-07;17(2):e0263586.
    Species: Human
    Sample Types: Amniotic Fluid
  119. Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment
    Authors: V Schimek, K Strasser, A Beer, S Göber, N Walterskir, C Brostjan, C Müller, T Bachleitne, M Bergmann, H Dolznig, R Oehler
    Cell Death & Disease, 2022-02-04;13(2):113.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air-Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs)
    Authors: S Offer, E Hartner, S Di Bucchia, C Bisig, S Bauer, J Pantzke, EJ Zimmermann, X Cao, S Binder, E Kuhn, A Huber, S Jeong, U Käfer, P Martens, A Mesceriako, J Bendl, R Brejcha, A Buchholz, D Gat, T Hohaus, N Rastak, G Jakobi, M Kalberer, T Kanashova, Y Hu, C Ogris, A Marsico, F Theis, M Pardo, T Gröger, S Oeder, J Orasche, A Paul, T Ziehm, ZH Zhang, T Adam, O Sippula, M Sklorz, J Schnelle-K, H Czech, A Kiendler-S, Y Rudich, R Zimmermann
    Environmental health perspectives, 2022-02-03;130(2):27003.
    Species: Human
    Sample Types: Cell Culture Supernates
  121. Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up
    Authors: B Grüner, L Peters, A Hillenbran, P Vo beta berg, J Schweiker, EG Rollmann, LH Rodriguez, J Blumhardt, S Burkert, P Kern, C Köhler, PT Soboslay
    PloS Neglected Tropical Diseases, 2022-02-02;16(2):e0010099.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement
    Authors: C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert
    International Journal of Molecular Sciences, 2022-01-28;23(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  123. Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma
    Authors: S Saxena, C Molczyk, A Purohit, E Ehrhorn, P Goel, DR Prajapati, P Atri, S Kaur, PM Grandgenet, MA Hollingswo, SK Batra, RK Singh
    American journal of cancer research, 2022-01-15;12(1):68-90.
    Species: Human
    Sample Types: Serum
  124. MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
    Authors: Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie
    Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269.
    Species: Human
    Sample Types: Cell Culture Supernates
  125. Slow degrading Mg-based materials induce tumor cell dormancy on an osteosarcoma-fibroblast coculture model
    Authors: P Globig, R Willumeit-, F Martini, E Mazzoni, BJC Luthringer
    Bioactive materials, 2021-12-30;16(0):320-333.
    Species: Human
    Sample Types: Cell Culture Supernates
  126. Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells
    Authors: AA Giese, A Babendreye, P Krappen, A Gross, P Strnad, S Düsterhöft, A Ludwig
    Scientific Reports, 2021-12-20;11(1):24230.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity
    Authors: M Rahman, M Irmler, S Keshavan, M Introna, J Beckers, L Palmberg, G Johanson, K Ganguly, S Upadhyay
    Viruses, 2021-12-17;13(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  128. Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma
    Authors: A Tosi, L Nardinocch, ML Carbone, L Capriotti, E Pagani, S Mastroeni, C Fortes, F Scopelliti, C Cattani, F Passarelli, A Rosato, S D'Atri, CM Failla, A Cavani
    Biomedicines, 2021-12-16;9(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  129. Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins
    Authors: R Roca-Pinil, R Holani, A López-Cano, C Saubi, R Baltà-Foix, ER Cobo, E Garcia-Fru, A Arís
    Scientific Reports, 2021-12-10;11(1):23798.
    Species: Human
    Sample Types: Cell Culture Supernates
  130. Infection with a hypervirulent strain of Helicobacter pylori primes gastric cells toward intestinal transdifferentiation
    Authors: S Saberi, M Esmaeili, M Tashakorip, M Eshagh Hos, H Baharvand, M Mohammadi
    Microbial pathogenesis, 2021-12-08;162(0):105353.
    Species: Human
    Sample Types: Cell Culture Supernates
  131. Toxicological transcriptome of human airway constructs after exposure to indoor air particulate matter: In search of relevant pathways of moisture damage-associated health effects
    Authors: ME Nordberg, M Täubel, S Heikkinen, K Jalkanen, A Köliö, M Stranger, H Leppänen, A Hyvärinen, K Huttunen
    Environment international, 2021-11-26;158(0):106997.
    Species: Human
    Sample Types: Cell Culture Supernates
  132. miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes
    Authors: K Dull, F Fazekas, D Deák, D Kovács, S Póliska, A Szegedi, CC Zouboulis, D Tör?csik
    Scientific Reports, 2021-11-02;11(1):21510.
    Species: Human
    Sample Types: Cell Culture Supernates
  133. DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen
    Authors: SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy
    International Journal of Molecular Sciences, 2021-10-15;22(20):.
    Species: Human
    Sample Types: Cell Culture Supernates
  134. A highly efficient method for the production and purification of recombinant human CXCL8
    Authors: S McKenna, SP Giblin, RA Bunn, Y Xu, SJ Matthews, JE Pease
    PLoS ONE, 2021-10-15;16(10):e0258270.
    Species: Human
    Sample Types: Recombinant Protein
  135. Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis
    Authors: X Zhu, Y Zhan, Y Gu, Q Huang, T Wang, Z Deng, J Xie
    Frontiers in Physiology, 2021-10-08;12(0):733650.
    Species: Human
    Sample Types: Cell Culture Supernates
  136. Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors
    Authors: L Liu, E Bankell, C Rippe, B Morén, KG Stenkula, BO Nilsson, K Swärd
    Frontiers in Physiology, 2021-10-04;12(0):732564.
    Species: Human
    Sample Types: Cell Lysates
  137. Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
    Authors: P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonn, L Liu, E Ruppin, L Wakefield, KW Wucherpfen
    Nature methods, 2021-09-30;18(10):1181-1191.
    Species: Human
    Sample Types: Cell Culture Supernates
  138. IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming
    Authors: N Niu, J Yao, RC Bast, AK Sood, J Liu
    Oncogenesis, 2021-09-29;10(9):65.
    Species: Human
    Sample Types: Cell Culture Supernates
  139. Multi-level inhibition of coronavirus replication by chemical ER stress
    Authors: MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht
    Nature Communications, 2021-09-20;12(1):5536.
    Species: Human
    Sample Types: Cell Culture Supernates
  140. Pulmonary function changes in older adults with and without metabolic syndrome
    Authors: MAR Brandao-Ra, R Moraes-Fer, MC Oliveira-J, A Santos-Dia, ALL Bachi, G Gabriela-P, S de Oliveir, AC Araújo-Ros, LVF Oliveira, CR Frison, WL do Prado, RP Raju, PB Balagopal, RP Vieira
    Scientific Reports, 2021-08-30;11(1):17337.
    Species: Human
    Sample Types: Exhaled Breath Condensate (EBC)
  141. Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1alpha kinase inhibitor KIRA6 through HSP60 targeting
    Authors: N Rufo, D Korovesis, S Van Eygen, R Derua, AD Garg, F Finotello, M Vara-Perez, J Rožanc, M Dewaele, PA de Witte, LG Alexopoulo, S Janssens, L Sinkkonen, T Sauter, SHL Verhelst, P Agostinis
    Cell Death and Differentiation, 2021-08-27;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  142. Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass
    Authors: M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié
    Journal of leukocyte biology, 2021-08-23;0(0):.
    Species: Human
    Sample Types: Plasma
  143. Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection
    Authors: G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi
    PloS Biology, 2021-08-19;19(8):e3001387.
    Species: Human
    Sample Types: Plasma
  144. The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways
    Authors: AF Santos, NSR Santos Mot, EM Schiefer, RS da Cunha, AM Junkert, AEM Stinghen, R Pontarolo, AR Crisma, AM Weffort-Sa, RC Pedrosa, WM de Souza, KB Felipe
    Journal of ethnopharmacology, 2021-08-09;0(0):114512.
    Species: Human
    Sample Types: Cell Culture Supernates
  145. Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction
    Authors: Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson
    Cell Death & Disease, 2021-08-06;12(8):775.
    Species: Human
    Sample Types: Cell Culture Supernates
  146. Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes
    Authors: E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz
    Biology, 2021-08-04;10(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  147. The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells
    Authors: J Cui, C Duizer, LI Bouwman, KS van Rooije, CGP Voogdt, JPM van Putten, MR de Zoete
    PloS Pathogens, 2021-08-02;17(8):e1009787.
    Species: Human
    Sample Types: Cell Culture Supernates
  148. Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis
    Authors: L Kandilogia, E Filidou, I Drygiannak, G Tarapatzi, S Didaskalou, M Koffa, K Arvanitidi, G Bamias, V Valatas, V Paspaliari, G Kolios
    Stem Cells International, 2021-07-27;2021(0):9929461.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. LYSMD3: A mammalian pattern recognition receptor for chitin
    Authors: X He, BA Howard, Y Liu, AK Neumann, L Li, N Menon, T Roach, SD Kale, DC Samuels, H Li, T Kite, H Kita, TY Hu, M Luo, CN Jones, UJ Okaa, DL Squillace, BS Klein, CB Lawrence
    Cell Reports, 2021-07-20;36(3):109392.
    Species: Human
    Sample Types: Cell Culture Supernates
  150. Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells
    Authors: B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero
    Polymers, 2021-07-18;13(14):.
    Species: Human
    Sample Types: Cell Culture Supernates
  151. Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells
    Authors: Y Hosokawa, I Hosokawa, K Ozaki
    Mediators of Inflammation, 2021-07-10;2021(0):5535844.
    Species: Human
    Sample Types: Cell Culture Supernates
  152. ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice
    Authors: JS Bourgeois, L Wang, AF Rabino, J Everitt, MI Alvarez, S Awadia, ES Wittchen, R Garcia-Mat, DC Ko
    PloS Pathogens, 2021-07-09;17(7):e1009713.
    Species: Human
    Sample Types: Cell Culture Supernates
  153. Characterization of low-density granulocytes in COVID-19
    Authors: LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin
    PloS Pathogens, 2021-07-06;17(7):e1009721.
    Species: Human
    Sample Types: Serum
  154. Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
    Authors: KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess
    Cells, 2021-06-29;10(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  155. An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles
    Authors: M Busch, AAM Kämpfer, RPF Schins
    Chemosphere, 2021-06-28;284(0):131345.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  156. Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
    Authors: YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang
    Arthritis Research & Therapy, 2021-06-16;23(1):171.
    Species: Human
    Sample Types: Cell Culture Supernates
  157. Food Contaminants Effects on an In Vitro Model of Human Intestinal Epithelium
    Authors: M Guibourden, J Haug, N Chevalier, M Spatz, N Barbezier, J Gay-Quéhei, PM Anton
    Toxics, 2021-06-09;9(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  158. Bacterial genotoxins induce T�cell senescence
    Authors: SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard
    Cell Reports, 2021-06-08;35(10):109220.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response
    Authors: M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich
    PloS Biology, 2021-06-01;19(6):e3001247.
    Species: Human
    Sample Types: Cell Culture Supernates
  160. HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
    Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
    Autophagy, 2021-05-24;0(0):1-20.
    Species: Rat
    Sample Types: Serum
  161. Synergistic cycles of protease activity and inflammation via PPAR&gamma degradation in chronic obstructive pulmonary disease
    Authors: N Kwak, KH Lee, J Woo, J Kim, CH Lee, CG Yoo
    Experimental & Molecular Medicine, 2021-05-21;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  162. Inflammatory responses to metal oxide ceramic nanopowders
    Authors: S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp
    Scientific Reports, 2021-05-18;11(1):10531.
    Species: Human
    Sample Types: Cell Culture Supernates
  163. Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration
    Authors: HK Skovdahl, S Gopalakris, TD Svendsen, AVB Granlund, I Bakke, ZG Ginbot, S Thorsvik, A Flatberg, B Sporsheim, J Ostrop, TE Mollnes, AK Sandvik, T Bruland
    Frontiers in Pharmacology, 2021-05-13;12(0):679741.
    Species: Human
    Sample Types: Cell Culture Supernates
  164. Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients
    Authors: W Johnston, BT Rosier, A Artacho, M Paterson, K Piela, C Delaney, JL Brown, G Ramage, A Mira, S Culshaw
    Scientific Reports, 2021-05-07;11(1):9796.
    Species: Human
    Sample Types: Saliva
  165. Plasma markers in pulmonary hypertension subgroups correlate with patient survival
    Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
    Respiratory Research, 2021-05-04;22(1):137.
    Species: Human
    Sample Types: Plasma
  166. Higher CD4/CD8 ratio of pleural effusion predicts better survival for lung cancer patients receiving immune checkpoint inhibitors
    Authors: PH Lee, TY Yang, KC Chen, YH Huang, JS Tseng, KH Hsu, YC Wu, KJ Liu, GC Chang
    Scientific Reports, 2021-04-30;11(1):9381.
    Species: Human
    Sample Types: Pleural Effusion
  167. Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations
    Authors: M Paximadis, ACP Picton, D Sengupta, M Ramsay, A Puren, CT Tiemessen
    Cytokine, 2021-04-01;0(0):155489.
    Species: Human
    Sample Types: Cell Culture Supernates
  168. Activation of NF-&kapppaB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion
    Authors: X Zhou, LJ Backman, P Danielson
    Scientific Reports, 2021-04-01;11(1):7360.
    Species: Human
    Sample Types: Cell Culture Supernates
  169. Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
    Authors: L Wang, D Aschenbren, Z Zeng, X Cao, D Mayr, M Mehta, M Capitani, N Warner, J Pan, L Wang, Q Li, T Zuo, S Cohen-Keda, J Lu, RC Ardy, DJ Mulder, D Dissanayak, K Peng, Z Huang, X Li, Y Wang, X Wang, S Li, S Bullers, AN Gammage, K Warnatz, AI Schiefer, G Krivan, V Goda, WHA Kahr, M Lemaire, Genomics E, CY Lu, I Siddiqui, MG Surette, D Kotlarz, KR Engelhardt, HR Griffin, R Rottapel, H Decaluwe, RM Laxer, M Proietti, S Hambleton, S Elcombe, CH Guo, B Grimbacher, I Dotan, SC Ng, SA Freeman, SB Snapper, C Klein, K Boztug, Y Huang, D Li, HH Uhlig, AM Muise
    Nature Genetics, 2021-03-29;53(4):500-510.
    Species: Human
    Sample Types: Cell Culture Supernates
  170. Production of IL-1&beta, IL-6 and CXCL8 by endometrium of crossbred heifers stimulated with various pathogen-associated molecular patterns
    Authors: PP Nunes, TDM Martins, AC Leite, EBM Silva, TA da Paixão, RL Santos, ÁM Borges
    Animal reproduction science, 2021-03-17;228(0):106736.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  171. Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets
    Authors: SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh
    Toxics, 2021-03-17;9(3):.
    Species: Human
    Sample Types: cell culture supernatant
  172. Polymicrobial stimulation of human fetal membranes induce neutrophil activation and neutrophil extracellular trap release
    Authors: M Tong, SE Hanna, VM Abrahams
    Journal of reproductive immunology, 2021-03-09;145(0):103306.
    Species: Human
    Sample Types: Cell Culture Supernates
  173. Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response
    Authors: MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad
    Cell Death & Disease, 2021-03-04;12(3):241.
    Species: Human
    Sample Types: Cell Culture Supernates
  174. Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
    Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
    Nature Communications, 2021-02-22;12(1):1209.
    Species: Human
    Sample Types: Cell Culture Supernates
  175. Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
    Authors: GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio
    Biomolecules, 2021-02-21;11(2):.
    Species: Human
    Sample Types: Plasma
  176. Genetic variation in Toll-like receptor-5 and colonization with flagellated bacterial vaginosis-associated bacteria
    Authors: EJ Dela Cruz, TL Fiedler, C Liu, MM Munch, CM Kohler, AR Oot, JM Wallis, J Wang, A Frishman, K Garcia, A Wiser, JE Balkus, S Srinivasan, JL Golob, LK Sycuro, JM Marrazzo, TR Hawn, DN Fredricks
    Infect Immun, 2021-02-16;0(0):.
    Species: Human
    Sample Types: Vaginal Swab
  177. Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
    Authors: P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski
    Arthritis Research & Therapy, 2021-02-15;23(1):56.
    Species: Human
    Sample Types: Cell Culture Supernates
  178. Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma
    Authors: JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman
    Scientific Reports, 2021-02-15;11(1):3802.
    Species: Human
    Sample Types: Cell Culture Supernates
  179. PHAIR: a biosensor for pH measurement in air-liquid interface cell culture
    Authors: M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota
    Scientific Reports, 2021-02-10;11(1):3477.
    Species: Human
    Sample Types: Cell Culture Supernates
  180. Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway
    Authors: MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito
    PLoS ONE, 2021-02-01;16(2):e0246050.
    Species: Human
    Sample Types: Cell Culture Supernates
  181. Early bilirubinemia after allogeneic stem cell transplantation-an endothelial complication
    Authors: H Dai, O Penack, A Radujkovic, D Schult, J Majer-Laut, IW Blau, L Bullinger, S Jiang, C Müller-Tid, P Dreger, T Luft
    Bone marrow transplantation, 2021-01-30;0(0):.
    Species: Human
    Sample Types: Serum
  182. The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells
    Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
    BioMed Research International, 2021-01-28;2021(0):8826586.
    Species: Human
    Sample Types: Cell Culture Supernates
  183. Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity
    Authors: M Heydarian, M Schweinlin, T Schwarz, R Rawal, H Walles, M Metzger, T Rudel, V Kozjak-Pav
    Journal of tissue engineering, 2021-01-28;12(0):2041731420988.
    Species: Human
    Sample Types: Cell Culture Supernates
  184. Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
    Authors: SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai
    Scientific Reports, 2021-01-14;11(1):1462.
    Species: Human
    Sample Types: Cell Culture Supernates
  185. A protein microarray analysis of amniotic fluid proteins for the prediction of spontaneous preterm delivery in women with preterm premature rupture of membranes at 23 to 30 weeks of gestation
    Authors: HJ Kim, KH Park, YM Kim, E Joo, K Ahn, S Shin
    PLoS ONE, 2020-12-31;15(12):e0244720.
    Species: Human
    Sample Types: Amniotic Fluid
  186. Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
    Authors: LJ Williams, SG Tristram, GR Zosky
    International Journal of Environmental Research and Public Health, 2020-12-28;18(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  187. Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells
    Authors: R Kolahdouz-, F Shidfar, S Khodaverdi, T Arablou, S Heidari, N Rashidi, AA Delbandi
    Journal of Cellular and Molecular Medicine, 2020-12-15;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  188. SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
    Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
    medRxiv : the preprint server for health sciences, 2020-12-09;0(0):.
    Species: Human
    Sample Types: Fecal Supernates
  189. Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist
    Authors: H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier
    Frontiers in Pharmacology, 2020-12-08;11(0):598702.
    Species: Human
    Sample Types: Cell Culture Supernates
  190. ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
    Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
    FEBS Open Bio, 2020-11-06;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  191. CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features
    Authors: M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi
    PLoS ONE, 2020-11-02;15(11):e0241719.
    Species: Human
    Sample Types: Serum
  192. Salivary IL-8 and IL-1RA changes induced by exercise in cold-dry and normal conditions
    Authors: I Patlan, MP Jeffrey, D Lewis, J Green-John, S Dogra
    Cytokine, 2020-10-28;137(0):155347.
    Species: Human
    Sample Types: Saliva
  193. Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy
    Authors: M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg
    Mol Ther, 2020-10-15;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  194. An observational study of innate immune responses in patients with acute appendicitis
    Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
    Sci Rep, 2020-10-15;10(1):17352.
    Species: Human
    Sample Types: Cell Culture Supernates
  195. N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM
    Authors: G Kaufman, D Skrtic
    Int J Mol Sci, 2020-10-03;21(19):.
    Species: Human
    Sample Types: Cell Culture Supernates
  196. Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells
    Authors: PT Tien, HJ Lin, YY Tsai, YP Lim, CS Chen, CY Chang, CJ Lin, JJ Chen, SM Wu, YJ Huang, L Wan
    Scientific Reports, 2020-09-24;10(1):15702.
    Species: Human
    Sample Types: Whole Cells
  197. Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions
    Authors: F Kolonics, E Kajdácsi, VJ Farkas, DS Veres, D Khamari, Á Kittel, ML Merchant, KR McLeish, ÁM L?rincz, E Ligeti
    J. Leukoc. Biol., 2020-09-18;0(0):.
    Species: Human
    Sample Types: Cell Supernates
  198. Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding
    Authors: A Iannucci, V Caneparo, S Raviola, I Debernardi, D Colangelo, R Miggiano, G Griffante, S Landolfo, M Gariglio, M De Andrea
    PLoS Pathog., 2020-09-09;16(9):e1008811.
    Species: Human
    Sample Types: Cell Culture Supernates
  199. Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells
    Authors: YD Jung, SK Park, D Kang, S Hwang, MH Kang, SW Hong, JH Moon, JS Shin, DH Jin, D You, JY Lee, YY Park, JJ Hwang, CS Kim, N Suh
    Redox Biol, 2020-09-09;37(0):101716.
    Species: Human
    Sample Types: Cell Culture Supernates
  200. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
    Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
    PLoS Pathog., 2020-08-18;16(8):e1008781.
    Species: Human
    Sample Types: Cell Culture Supernates
  201. Identification and toxicological evaluation of cyclic sulfonium ion degradation products of sulphur mustard
    Authors: P Hemström, KH Holmgren, BE Hammarströ, A Larsson, A Östin
    Mar. Environ. Res., 2020-08-07;162(0):105047.
    Species: Human
    Sample Types: Cell Culture Supernates
  202. Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn's disease
    Authors: L Allais, S Verschuere, T Maes, R De Smet, S Devriese, GB Gonzales, H Peeters, K Van Crombr, C Bachert, M De Vos, GG Brusselle, KR Bracke, CA Cuvelier, D Laukens
    PLoS ONE, 2020-08-06;15(8):e0236657.
    Species: Human
    Sample Types: Cell Culture Supernates
  203. SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells
    Authors: AE Wyman, TTT Nguyen, P Karki, ME Tulapurkar, CO Zhang, J Kim, TG Feng, AJ Dabo, NW Todd, IG Luzina, P Geraghty, RF Foronjy, JD Hasday, AA Birukova, SP Atamas, KG Birukov
    Sci Rep, 2020-07-27;10(1):12497.
    Species: Human
    Sample Types: Cell Culture Supernates
  204. Extracellular Vesicles Produced by the Probiotic Propionibacterium freudenreichii CIRM-BIA 129 Mitigate Inflammation by Modulating the NF-&kappaB Pathway
    Authors: VR Rodovalho, BSR da Luz, H Rabah, FLR do Carmo, EL Folador, A Nicolas, J Jardin, V Briard-Bio, H Blottière, N Lapaque, G Jan, Y Le Loir, VA de Carvalh, E Guédon
    Front Microbiol, 2020-07-07;11(0):1544.
    Species: Human
    Sample Types: Cell Culture Supernates
  205. The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore
    Authors: S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski
    Front Pharmacol, 2020-07-03;11(0):983.
    Species: Human
    Sample Types: Cell Culture Supernates
  206. Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival
    Authors: HF Hazlett, TH Hampton, DS Aridgides, DA Armstrong, JA Dessaint, DL Mellinger, AB Nymon, A Ashare
    Sci Rep, 2020-07-02;10(1):10935.
    Species: Human
    Sample Types: Whole Cells
  207. The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification
    Authors: E Zuccolo, I Badi, F Scavello, I Gambuzza, L Mancinelli, F Macrì, CC Tedesco, F Veglia, AR Bonfigli, F Olivieri, A Raucci
    Int J Mol Sci, 2020-06-23;21(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  208. TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies
    Authors: LM Gierman, GB Silva, Z Pervaiz, JJ Rakner, SB Mundal, AJ Thaning, I Nervik, M Elschot, S Mathew, LCV Thomsen, L Bjørge, AC Iversen
    J. Leukoc. Biol., 2020-06-23;0(0):.
    Species: Human
    Sample Types: Placental Supernates
  209. Data describing expression of formyl peptide receptor 2 in human articular chondrocytes
    Authors: A Strid Holm, CA Jonsson, M Mohaddes, C Lundqvist, H Forsman, I Gjertsson, K Önnheim
    Data Brief, 2020-06-16;31(0):105866.
    Species: Human
    Sample Types: Cell Culture Supernates
  210. OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion
    Authors: T O'Loughlin, AJ Kruppa, ALR Ribeiro, JR Edgar, A Ghannam, AM Smith, F Buss
    J. Cell. Sci., 2020-06-15;0(0):.
    Species: Human
    Sample Types: Tissue Culture Supernates
  211. Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide
    Authors: V Spiegler, B Gierlikows, T Saenger, JN Addotey, J Sendker, J Jose, AK Kiss, A Hensel
    Front Pharmacol, 2020-06-12;11(0):889.
    Species: Human
    Sample Types: Cell Culture Supernates
  212. Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells
    Authors: R Nallathamb, A Poulev, JB Zuk, I Raskin
    Nutrients, 2020-06-01;12(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  213. Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnusrhamnoides (L.) A. Nelson-The Implications for Human Barrier Cells
    Authors: B Sadowska, J Rywaniak, A Cichocka, K Cichocka, J ?uchowski, U Wójcik-Boj, M Wi?ckowska, B Ró?alska
    Molecules, 2020-05-09;25(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  214. N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
    Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
    Nat Commun, 2020-05-05;11(1):2212.
    Species: Human
    Sample Types: Cell Culture Supernates
  215. Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses
    Authors: L Mercurio, CM Failla, L Capriotti, C Scarponi, F Facchiano, M Morelli, S Rossi, G Pagnanelli, C Albanesi, A Cavani, S Madonna
    PLoS ONE, 2020-04-30;15(4):e0222969.
    Species: Human
    Sample Types: Cell Culture Supernates
  216. Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
    Authors: FJ Ryan, AM Ahern, RS Fitzgerald, EJ Laserna-Me, EM Power, AG Clooney, KW O'Donoghue, PJ McMurdie, S Iwai, A Crits-Chri, D Sheehan, C Moran, B Flemer, AL Zomer, A Fanning, J O'Callagha, J Walton, A Temko, W Stack, L Jackson, SA Joyce, S Melgar, TZ DeSantis, JT Bell, F Shanahan, MJ Claesson
    Nat Commun, 2020-03-23;11(1):1512.
    Species: Human
    Sample Types: Cell Culture Supernates
  217. Diet influences the functions of the human intestinal microbiome
    Authors: M De Angelis, I Ferrocino, FM Calabrese, F De Filippi, N Cavallo, S Siragusa, S Rampelli, R Di Cagno, K Rantsiou, L Vannini, N Pellegrini, C Lazzi, S Turroni, N Lorusso, M Ventura, M Chieppa, E Neviani, P Brigidi, PW O'Toole, D Ercolini, M Gobbetti, L Cocolin
    Sci Rep, 2020-03-06;10(1):4247.
    Species: Human
    Sample Types: Cell Culture Supernates
  218. Ibrutinib induces multiple functional defects in the neutrophil response against Aspergillus fumigatus
    Authors: D Blez, M Blaize, C Soussain, A Boissonnas, A Meghraoui-, N Menezes, A Portalier, C Combadière, V Leblond, D Ghez, A Fekkar
    Haematologica, 2020-01-31;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  219. Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction
    Authors: B Wernly, V Paar, A Aigner, PM Pilz, BK Podesser, M Förster, C Jung, JP Hofbauer, B Tockner, M Wimmer, T Kraus, LJ Motloch, M Hackl, UC Hoppe, A Kiss, M Lichtenaue
    Cells, 2020-01-25;9(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  220. The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
    Authors: T Furukawa, N van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, R Fortune-Gr, S Rahman, JM Gilsenan, E Houlder, CH Kowalski, S Raj, S Paul, P Cook, JE Parker, S Kelly, RA Cramer, JP Latgé, S Moye-Rowle, E Bignell, P Bowyer, MJ Bromley
    Nat Commun, 2020-01-22;11(1):427.
    Species: Human
    Sample Types: Cell Culture Supernates
  221. Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
    Authors: I Gomez, B Ward, C Souilhol, C Recarti, M Ariaans, J Johnston, A Burnett, M Mahmoud, LA Luong, L West, M Long, S Parry, R Woods, C Hulston, B Benedikter, C Niespolo, R Bazaz, S Francis, E Kiss-Toth, M van Zandvo, A Schober, P Hellewell, PC Evans, V Ridger
    Nat Commun, 2020-01-10;11(1):214.
    Species: Human
    Sample Types: Cell Culture Supernates
  222. Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes
    Authors: R Riise, L Odqvist, J Mattsson, S Monkley, SM Abdillahi, C Tyrchan, D Muthas, LF Yrlid
    Sci Rep, 2019-12-31;9(1):20407.
    Species: Human
    Sample Types: Cell Culture Supernates
  223. FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells
    Authors: J Gimenes-Ju, N Owuar, HR Vari, W Li, N Xander, S Kotnala, US Sajjan
    Sci Rep, 2019-12-03;9(1):18180.
    Species: Human
    Sample Types: Cell Culture Supernates
  224. C13 Megastigmane Derivatives From Epipremnum pinnatum: beta-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-kappaB Signaling
    Authors: SP Pan, T Pirker, O Kunert, N Kretschmer, S Hummelbrun, SL Latkolik, J Rappai, VM Dirsch, V Bochkov, R Bauer
    Front Pharmacol, 2019-11-28;10(0):1351.
    Species: Human
    Sample Types: Cell Culture Supernates
  225. LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD
    Authors: J Knobloch, D Jungck, J Kronsbein, E Stoelben, K Ito, A Koch
    J Clin Med, 2019-11-22;8(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  226. Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
    Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2019-11-01;60(14):4820-4829.
    Species: Human
    Sample Types: Cell Culture Supernates
  227. Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium
    Authors: RF Hoffmann, MR Jonker, SM Brandenbur, HG de Bruin, NHT Ten Hacken, AJM van Ooster, IH Heijink
    Sci Rep, 2019-10-21;9(1):15047.
    Species: Human
    Sample Types: Cell Culture Supernates
  228. Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
    Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
    BMC Sports Sci Med Rehabil, 2019-10-18;11(0):23.
    Species: Human
    Sample Types: Saliva
  229. IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin
    Authors: I Tsilioni, AB Patel, H Pantazopou, S Berretta, P Conti, SE Leeman, TC Theoharide
    Proc. Natl. Acad. Sci. U.S.A., 2019-10-07;0(0):.
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  230. ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12
    Authors: L Kloss, C Dollt, K Schledzews, A Krewer, S Melchers, C Manta, C Sticht, C Torre, J Utikal, V Umansky, A Schmieder
    Cell Death Dis, 2019-10-07;10(10):760.
    Species: Human
    Sample Types: Cell Culture Supernates
  231. 6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential
    Authors: IJ Yeh, SC Chen, MC Yen, YH Wu, CH Hung, PL Kuo
    Nutrients, 2019-09-28;11(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  232. Ouabain signaling in oral squamous cell carcinoma cells
    Authors: S Saito, M Ohtsu, M Asano, T Ishigami
    J Oral Sci, 2019-09-20;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  233. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression
    Authors: Q Xu, Q Long, D Zhu, D Fu, B Zhang, L Han, M Qian, J Guo, J Xu, L Cao, YE Chin, JP Coppé, EW Lam, J Campisi, Y Sun
    Aging Cell, 2019-09-07;0(0):e13027.
    Species: Human
    Sample Types: Serum
  234. Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma
    Authors: J Qiao, EJ Rellinger, KW Kim, CM Powers, S Lee, H Correa, DH Chung
    Oncotarget, 2019-08-20;10(49):5028-5040.
    Species: Human
    Sample Types: Cell Culture Supernates
  235. Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
    Authors: CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, C Solórzano, M Noursadegh, JS Brown, DM Ferreira, RS Heyderman
    Nat Commun, 2019-07-16;10(1):3060.
    Species: Human
    Sample Types: Cell Culture Supernates
  236. Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation
    Authors: N Schaunaman, A Sanchez, KG Dimasuay, N Pavelka, M Numata, R Alam, RJ Martin, HW Chu
    Infect. Immun., 2019-06-20;87(7):.
    Species: Human
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  237. Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
    Authors: H Fleury, N Malaquin, V Tu, S Gilbert, A Martinez, MA Olivier, A Sauriol, L Communal, K Leclerc-De, E Carmona, D Provencher, AM Mes-Masson, F Rodier
    Nat Commun, 2019-06-11;10(1):2556.
    Species: Human
    Sample Types: Cell Culture Supernates
  238. The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis
    Authors: P Dimou, RD Wright, KL Budge, A Midgley, SC Satchell, M Peak, MW Beresford
    Sci Rep, 2019-06-06;9(1):8348.
    Species: Human
    Sample Types: Cell Culture Supernates
  239. A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer
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    Cancers (Basel), 2019-05-13;11(5):.
    Species: Human
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  240. Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
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    PLoS Negl Trop Dis, 2019-05-08;13(5):e0007354.
    Species: Human
    Sample Types: Cell Culture Supernates
  241. Activation of a TLR9 mediated innate immune response in preeclampsia
    Authors: RD Williamson, FP McCarthy, LC Kenny, CM McCarthy
    Sci Rep, 2019-04-11;9(1):5920.
    Species: Human
    Sample Types: Plasma
  242. Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF
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    Sample Types: Cell Culture Supernates
  243. Evaluating S. flexneri pathogenesis in the human enteroid model
    Authors: S Ranganatha, M Doucet, CL Grassel, B Delaine-El, NC Zachos, EM Barry
    Infect. Immun., 2019-03-25;0(0):.
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  244. An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation
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    J Biomech, 2019-03-22;0(0):.
    Species: Human
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  245. The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
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    Sci Rep, 2019-03-13;9(1):4334.
    Species: Human
    Sample Types: Tissue Culture Supernates
  246. R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation
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    Species: Human
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  247. ?-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY
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  248. Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
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    Species: Human
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  249. Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5
    Authors: S Giuliano, M Dufies, PD Ndiaye, J Viotti, D Borchielli, J Parola, V Vial, Y Cormerais, M Ohanna, V Imbert, E Chamorey, N Rioux-Lecl, A Savina, JM Ferrero, B Mograbi, G Pagès
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    Exp. Gerontol., 2019-01-16;118(0):78-87.
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    Species: Human
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  252. Neutrophil recruitment to inflamed joints can occur without cellular priming
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    Species: Human
    Sample Types: Cell Lysates
  253. Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
    Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
    PLoS Pathog., 2018-12-07;14(12):e1007469.
    Species: Human
    Sample Types: Cell Culture Supernates
  254. Copy number variations and founder effect underlying complete IL-10R? deficiency in Portuguese kindreds
    Authors: F Charbit-He, B Bègue, A Sierra, S Hanein, MC Stolzenber, Z Li, S Pellegrini, N Garcelon, M Jeanpierre, B Neven, I Loge, C Picard, J Rosain, J Bustamante, M Le Lorc'h, B Pigneur, A Fernandes, F Rieux-Lauc, J Amil Dias, FM Ruemmele, N Cerf-Bensu
    PLoS ONE, 2018-10-26;13(10):e0205826.
    Species: Human
    Sample Types: Cell Culture Supernates
  255. Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance
    Authors: F Chen, Q Long, D Fu, D Zhu, Y Ji, L Han, B Zhang, Q Xu, B Liu, Y Li, S Wu, C Yang, M Qian, J Xu, S Liu, L Cao, YE Chin, EW Lam, JP Coppé, Y Sun
    Nat Commun, 2018-10-17;9(1):4315.
    Species: Human
    Sample Types: Serum
  256. Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury
    Authors: N Shologu, M Scully, JG Laffey, D O'Toole
    Int J Mol Sci, 2018-09-30;19(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  257. Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma
    Authors: T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe
    Lab. Invest., 2018-09-25;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  258. Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
    Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
    Biol. Reprod., 2018-09-01;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  259. Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells
    Authors: B Ku?nar-Kam, J Miku?a-Pie, A Witucka, A Romaniuk, N Konieczna, B Rubi?, K Ksi??ek, A Tykarski, H Batura-Gab
    Sci Rep, 2018-08-28;8(1):12940.
    Species: Human
    Sample Types: Cell Culture Supernates
  260. IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
    Authors: AC Gross, H Cam, DA Phelps, AJ Saraf, HK Bid, M Cam, CA London, SA Winget, MA Arnold, L Brandolini, X Mo, JM Hinckley, PJ Houghton, RD Roberts
    JCI Insight, 2018-08-23;3(16):.
    Species: Human
    Sample Types: Cell Culture Supernates
  261. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
    Nat Commun, 2018-08-15;9(1):3267.
    Species: Human
    Sample Types: Cell Culture Supernates
  262. Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
    Authors: P Daull, S Guenin, V Hamon de A, JS Garrigue
    Mol. Vis., 2018-07-20;24(0):459-470.
    Species: Human
    Sample Types: Cell Culture Supernates
  263. PGL I expression in live bacteria allows activation of a CD206/PPAR? cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves
    Authors: CC Díaz Acost, AA Dias, TLSA Rosa, LR Batista-Si, PS Rosa, TG Toledo-Pin, FDMR Costa, FA Lara, LS Rodrigues, KA Mattos, EN Sarno, PT Bozza, C Guilhot, M de Berrêdo, MCV Pessolani
    PLoS Pathog., 2018-07-06;14(7):e1007151.
    Species: Human
    Sample Types: Cell Culture Supernates
  264. Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages
    Authors: RA Mubarak, N Roberts, RJ Mason, S Alper, HW Chu
    Respir. Res., 2018-06-25;19(1):126.
    Species: Human
    Sample Types: Cell Culture Supernates
  265. Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands
    Authors: D Tör?csik, D Kovács, S Póliska, Z Szentkeres, M Lovászi, K Hegyi, A Szegedi, CC Zouboulis, M Ståhle
    PLoS ONE, 2018-06-21;13(6):e0198323.
    Species: Human
    Sample Types: Cell Culture Supernates
  266. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
    Authors: I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, D Clancy, J Brezinova, T Hu, A Bileck, C Gerner, A Bolado, A von Kriegs, SJ Martin, F Steinberg, K Strisovsky, C Adrain
    Elife, 2018-06-13;7(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  267. Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations
    Authors: JA Fraser, S Kemp, L Young, M Ross, M Prach, GR Hutchison, E Malone
    Sci Rep, 2018-05-14;8(1):7506.
    Species: Human
    Sample Types: Cell Culture Supernates
  268. CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
    Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
    Oncol Lett, 2018-04-17;15(6):9075-9080.
    Species: Human
    Sample Types: Cell Culture Supernates
  269. Age-Related Changes to Human Tear Composition
    Authors: A Micera, A Di Zazzo, G Esposito, R Longo, W Foulsham, R Sacco, R Sgrulletta, S Bonini
    Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2024-2031.
    Species: Human
    Sample Types: Tears
  270. Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function
    Authors: TM Nordgren, KL Bailey, AJ Heires, D Katafiasz, DJ Romberger
    Toxicol. Sci., 2018-04-01;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  271. Variable localization of Toll-like receptors in human fallopian tube epithelial cells
    Authors: F Amjadi, Z Zandieh, E Salehi, R Jafari, N Ghasemi, A Aflatoonia, A Fazeli, R Aflatoonia
    Clin Exp Reprod Med, 2018-03-30;45(1):1-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  272. Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
    Authors: D Zhang, J Qin, L Li, G Su, G Huang, Q Cao, A Kijlstra, P Yang
    Sci Rep, 2018-03-19;8(1):4850.
    Species: Human
    Sample Types: Cell Culture Supernates
  273. Rhododendron album Blume extract inhibits TNF-?/IFN-?-induced chemokine production via blockade of NF-?B and JAK/STAT activation in human epidermal keratinocytes
    Authors: JW Park, HS Lee, Y Lim, JH Paik, OK Kwon, JH Kim, I Paryanto, P Yunianto, S Choi, SR Oh, KS Ahn
    Int. J. Mol. Med., 2018-03-09;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  274. The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages
    Authors: SR Lea, SL Reynolds, M Kaur, KD Simpson, SR Hall, EM Hessel, D Singh
    Int J Chron Obstruct Pulmon Dis, 2018-03-02;13(0):771-780.
    Species: Human
    Sample Types: Cell Culture Supernates
  275. Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
    Authors: Z Zeng, M Li, J Chen, Q Li, Q Ning, J Zhao, Y Xu, J Xie, J Yu
    Int J Chron Obstruct Pulmon Dis, 2018-02-28;13(0):703-715.
    Species: Human
    Sample Types: Cell Culture Supernates
  276. Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
    Authors: I Tomašek, CJ Horwell, C Bisig, DE Damby, P Comte, J Czerwinski, A Petri-Fink, MJD Clift, B Drasler, B Rothen-Rut
    Environ. Pollut., 2018-02-16;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  277. SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells
    Authors: S Di Vincenz, IH Heijink, JA Noordhoek, C Cipollina, L Siena, A Bruno, M Ferraro, DS Postma, M Gjomarkaj, E Pace
    J. Cell. Mol. Med., 2018-02-07;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  278. Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
    Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
    Invest. Ophthalmol. Vis. Sci., 2018-02-01;59(2):1158-1166.
    Species: Human
    Sample Types: Cell Culture Supernates
  279. Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression
    Authors: CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan
    EBioMedicine, 2018-01-31;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  280. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018-01-24;8(1):1561.
    Species: Human
    Sample Types: Cell Culture Supernates
  281. Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment
    Authors: JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich
    MBio, 2018-01-23;9(1):.
    Species: Human
    Sample Types: Whole Blood
  282. TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
    Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
    Eur Cell Mater, 2018-01-19;35(0):13-24.
  283. Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes
    Authors: M Tohyama, Y Shirakata, Y Hanakawa, X Dai, K Shiraishi, M Murakami, S Miyawaki, H Mori, R Utsunomiya, K Masuda, K Hashimoto, K Sayama
    Eur. J. Immunol., 2017-11-20;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  284. Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine
    Authors: L Aubert, M Dubus, H Rammal, C Bour, C Mongaret, C Boulagnon-, R Garnotel, C Schneider, R Rahouadj, C Laurent, SC Gangloff, F Velard, C Mauprivez, H Kerdjoudj
    Int J Mol Sci, 2017-10-21;18(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  285. IL-27 Modulates Chemokine Production in TNF-? -Stimulated Human Oral Epithelial Cells
    Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
    Cell. Physiol. Biochem., 2017-10-05;43(3):1198-1206.
    Species: Human
    Sample Types: Cell Culture Supernates
  286. The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors
    Authors: J Miku?a-Pie, P Uruski, S Szubert, K Maksin, R Moszy?ski, D Szpurek, A Wo?niak, S Sajdak, A Tykarski, K Ksi??ek
    Biomed Res Int, 2017-09-20;2017(0):2592496.
    Species: Human
    Sample Types: Cell Culture Supernates
  287. Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model
    Authors: TJJ Schirris, J Jansen, M Mihajlovic, LP van den He, R Masereeuw, FGM Russel
    Sci Rep, 2017-09-06;7(1):10623.
    Species: Human
    Sample Types: Cell Culture Supernates
  288. Increased expression of Siglec-9 in chronic obstructive pulmonary disease
    Authors: Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie
    Sci Rep, 2017-08-31;7(1):10116.
    Species: Human
    Sample Types: Cell Culture Supernates
  289. Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
    Authors: RM Petri, A Hackel, K Hahnel, CA Dumitru, K Bruderek, SB Flohe, A Paschen, S Lang, S Brandau
    Stem Cell Reports, 2017-08-03;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  290. Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
    Authors: M Mihajlovic, LP van den He, JG Hoenderop, J Jansen, MJ Wilmer, AJF Westheim, WA Allebes, D Stamatiali, LB Hilbrands, R Masereeuw
    Sci Rep, 2017-08-02;7(1):7103.
    Species: Human
    Sample Types: Cell Culture Supernates
  291. Alpha1-antitrypsin binds hemin and prevents oxidative activation of human neutrophils: putative pathophysiological significance
    Authors: S Janciauski, S Tumpara, M Wiese, S Wrenger, V Vijayan, F Gueler, R Chen, K Madyaningr, R Mahadeva, T Welte, S Immenschuh, J Chorostows
    J. Leukoc. Biol., 2017-07-17;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  292. The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells
    Authors: A Hongo, N Okumura, M Nakahara, EP Kay, N Koizumi
    Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3325-3334.
    Species: Human
    Sample Types: Cell Culture Supernates
  293. The Role of Shed PrP(c) in the Neuropathogenesis of HIV Infection
    Authors: BW Megra, EA Eugenin, JW Berman
    J. Immunol., 2017-05-22;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  294. Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
    Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
    Sci Rep, 2017-05-12;7(1):1815.
    Species: Human
    Sample Types: Cell Culture Supernates
  295. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
    Authors: Lynne A Murray, Rebecca Dunmore, Ana Camelo, Carla A Da Silva, Malin J Gustavsso, David M Habiel, Tillie L Hackett, Cory M Hogaboam, Matthew A Sleeman, Darryl A Knight
    Respiratory Research, 2017-05-03;0(0):1465-993X.
    Species: Human
    Sample Types: Cell Culture Supernates
  296. Malaria pigment stimulates chemokine production by human microvascular endothelium
    Authors: N Basilico, Y Corbett, S Alessandro, S Parapini, M Prato, D Girelli, P Misiano, P Olliaro, D Taramelli
    Acta Trop., 2017-05-02;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  297. Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression
    Authors: A Ghosh, SH Abdelwahab, SL Reeber, B Reidel, AJ Marklew, AJ Garrison, S Lee, H Dang, AH Herring, GL Glish, M Kesimer, R Tarran
    Sci Rep, 2017-04-27;7(0):46239.
    Species: Human
    Sample Types: Cell Culture Supernates
  298. Experimental type 2 diabetes induction reduces serum vaspin, but not serum omentin, in Wistar rats
    Authors: CA Castro, KA da Silva, MM Buffo, KNZ Pinto, FO Duarte, KO Nonaka, FF Aníbal, ACGO Duarte
    Int J Exp Pathol, 2017-04-25;0(0):.
    Species: Human
    Sample Types: Serum
  299. Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells.
    Authors: Patel A, Theoharides T
    J Pharmacol Exp Ther, 2017-04-12;361(3):462-471.
    Species: Human
    Sample Types: Cell Culture Supernates
  300. Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors
    Authors: AH Bryant, GE Menzies, LM Scott, S Spencer-Ha, LB Davies, RA Smith, RH Jones, CA Thornton
    Clin. Exp. Immunol, 2017-03-31;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  301. Frequency and clinical significance of short cervix in patients with preterm premature rupture of membranes
    Authors: SM Lee, KH Park, EY Jung, JA Jang, HN Yoo
    PLoS ONE, 2017-03-30;12(3):e0174657.
    Species: Human
    Sample Types: Amniotic Fluid
  302. Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
    Authors: L Chen, MS Eapen, GR Zosky
    Sci Rep, 2017-03-27;7(0):45172.
    Species: Human
    Sample Types: Cell Culture Supernates
  303. The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?
    Authors: YA Hayman, LR Sadofsky, JD Williamson, SP Hart, AH Morice
    ERJ Open Res, 2017-03-20;3(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  304. Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture
    Authors: JW Park, KH Park, EY Jung
    PLoS ONE, 2017-03-09;12(3):e0173312.
    Species: Human
    Sample Types: Amniotic Fluid
  305. Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells
    Authors: V Selvarani, S Roland, S Andy, H James
    Virus Res, 2017-03-07;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  306. Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks' Gestation or Less
    Authors: EY Jung, KH Park, BR Han, SH Cho, HN Yoo, J Lee
    J. Korean Med. Sci, 2017-03-01;32(3):480-487.
    Species: Human
    Sample Types: Amniotic Fluid
  307. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
    Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
    Immun Ageing, 2017-02-22;14(0):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  308. Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
    Authors: CM Henry, SJ Martin
    Mol. Cell, 2017-02-16;65(4):715-729.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  309. The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
    Authors: T Hartwig, A Montinaro, S von Karste, A Sevko, S Surinova, A Chakravart, L Taraborrel, P Draber, E Lafont, F Arce Varga, MA El-Bahrawy, SA Quezada, H Walczak
    Mol. Cell, 2017-02-16;65(4):730-742.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  310. Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
    Authors: A Granitzny, J Knebel, M Müller, A Braun, P Steinberg, C Dasenbrock, T Hansen
    Toxicol Rep, 2017-02-12;4(0):89-103.
    Species: Human
    Sample Types: Cell Culture Supernates
  311. Chlamydial Lipoproteins Stimulate Toll-Like Receptors 1/2 Mediated Inflammatory Responses through MyD88-Dependent Pathway
    Authors: Y Wang, Q Liu, D Chen, J Guan, L Ma, G Zhong, H Shu, X Wu
    Front Microbiol, 2017-01-26;8(0):78.
    Species: Human
    Sample Types: Cell Culture Supernates
  312. Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-?B-mediated cytokine production
    Authors: Soh Yamamoto
    Biochem. Biophys. Res. Commun, 2016-12-18;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  313. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
    Sci Rep, 2016-12-15;6(0):39035.
    Species: Human
    Sample Types: Cell Culture Supernates
  314. Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
    Authors: Ines Tomašek
    Part Fibre Toxicol, 2016-12-12;13(1):67.
    Species: Human
    Sample Types: Cell Culture Supernates
  315. The Anti-inflammatory Effect of Alpha-1 Antitrypsin in Rhinovirus-infected Human Airway Epithelial Cells
    Authors: D Jiang, R Berman, Q Wu, C Stevenson, HW Chu
    J Clin Cell Immunol, 2016-12-05;7(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  316. Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma
    Respir. Res., 2016-11-16;17(1):153.
    Species: Human
    Sample Types: Cell Culture Supernates
  317. Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts
    Evid Based Complement Alternat Med, 2016-10-11;2016(0):5357689.
    Species: Human
    Sample Types: Cell Culture Supernates
  318. Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating
    J Control Release, 2016-09-26;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  319. Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages
    Infect Immun, 2016-09-19;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  320. Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid
    Authors: Jae Sung Hwang
    Biomol Ther (Seoul), 2016-09-01;24(5):529-35.
    Species: Human
    Sample Types: Cell Culture Supernates
  321. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells
    Sci Rep, 2016-09-01;6(0):32505.
    Applications: ChIP
  322. IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium
    J Immunol, 2016-08-17;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  323. mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages
    Authors: S Danesh Mes, J Sharbati, R Einspanier, C Gabler
    Reprod. Biol. Endocrinol, 2016-08-15;14(1):44.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  324. Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells
    PLoS ONE, 2016-07-21;11(7):e0154102.
    Species: Human
    Sample Types: Cell Culture Supernates
  325. Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome
    PLoS ONE, 2016-07-14;11(7):e0158969.
    Species: Human
    Sample Types: Cell Culture Supernates
  326. The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma
    Cell Signal, 2016-07-11;28(10):1555-1562.
    Species: Human
    Sample Types: Cell Culture Supernates
  327. Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility
    Authors: Cleriston Farias Queiroz
    J Bras Pneumol, 2016-07-01;42(4):241-247.
    Species: Human
    Sample Types: Serum
  328. A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro
    Authors: Brian G Oliver
    Thorax, 2016-06-10;71(11):1039-1049.
    Species: Human
    Sample Types: Cell Culture Supernates
  329. Engineering a 3D microfluidic culture platform for tumor-treating field application
    Sci Rep, 2016-05-24;6(0):26584.
    Species: Human
    Sample Types: Cell Culture Supernates
  330. Local host response following an intramammary challenge with Staphylococcus fleurettii and different strains of Staphylococcus chromogenes in dairy heifers
    Authors: K Piccart, J Verbeke, A De Vissche, S Piepers, F Haesebrouc, S De Vlieghe
    Vet. Res., 2016-05-12;47(1):56.
    Species: Bovine
    Sample Types: Milk
  331. Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin
    J Immunol, 2016-04-29;196(11):4681-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  332. Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
    Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
    Sci Rep, 2016-04-25;6(0):24974.
    Species: Human
    Sample Types: Cell Culture Supernates
  333. CREB regulates TNF-?-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts
    Authors: Y Koga, T Hisada, T Ishizuka, M Utsugi, A Ono, M Yatomi, Y Kamide, H Aoki-Saito, H Tsurumaki, K Dobashi, M Yamada
    Allergol Int, 2016-04-22;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  334. Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
    Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
    PLoS ONE, 2016-04-05;11(4):e0153118.
    Species: Human
    Sample Types: Cell Culture Supernates
  335. Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p.
    Authors: Wotschofsky Z, Gummlich L, Liep J, Stephan C, Kilic E, Jung K, Billaud J, Meyer H
    PLoS ONE, 2016-02-09;11(2):e0148746.
    Species: Human
    Sample Types: Cell Culture Supernates
  336. C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
    J Immunol, 2016-01-22;196(5):2319-26.
    Species: Human
    Sample Types: Cell Culture Supernates
  337. Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis.
    Authors: Healey G, Collier C, Griffin S, Schuberth H, Sandra O, Smith D, Mahan S, Dieuzy-Labaye I, Sheldon I
    J Immunol, 2015-12-16;196(2):823-31.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  338. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.
    Authors: Casilag F, Lorenz A, Krueger J, Klawonn F, Weiss S, Haussler S
    Infect Immun, 2015-10-26;84(1):162-71.
    Species: Human
    Sample Types: Cell Culture Supernates
  339. Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis.
    Authors: Harbort C, Soeiro-Pereira P, von Bernuth H, Kaindl A, Costa-Carvalho B, Condino-Neto A, Reichenbach J, Roesler J, Zychlinsky A, Amulic B
    Blood, 2015-10-21;126(26):2842-51.
    Species: Human
    Sample Types: Cell Culture Supernates
  340. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
    Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
    Reprod Biol Endocrinol, 2015-10-07;13(0):115.
    Species: Human
    Sample Types: Cell Culture Supernates
  341. Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
    Authors: Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock I, Wort S
    Respir Res, 2015-09-18;16(0):114.
    Species: Human
    Sample Types: Cell Culture Supernates
  342. Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells.
    Authors: Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K
    PLoS ONE, 2015-09-18;10(9):e0138267.
    Species: Human
    Sample Types: Cell Culture Supernates
  343. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
    Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
    Eur J Immunol, 2015-08-17;45(10):2937-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  344. Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma.
    Authors: Fernandez-Bertolin L, Mullol J, Fuentes-Prado M, Roca-Ferrer J, Alobid I, Picado C, Pujols L
    PLoS ONE, 2015-05-05;10(5):e0125443.
    Species: Human
    Sample Types: Cell Culture Supernates
  345. Detection and characterisation of Lactobacillus spp. in the bovine uterus and their influence on bovine endometrial epithelial cells in vitro.
    Authors: Gartner M, Bondzio A, Braun N, Jung M, Einspanier R, Gabler C
    PLoS ONE, 2015-03-24;10(3):e0119793.
    Species: Human
    Sample Types: Cell Culture Supernates
  346. Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
    Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
    PLoS ONE, 2015-03-10;10(3):e0119727.
    Species: Human
    Sample Types: Cell Culture Supernates
  347. Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.
    Authors: Puig K, Manocha G, Combs C
    PLoS ONE, 2015-03-05;10(3):e0119534.
    Species: Human
    Sample Types: Cell Culture Supernates
  348. Role of hydrogen sulfide in paramyxovirus infections.
    Authors: Li H, Ma Y, Escaffre O, Ivanciuc T, Komaravelli N, Kelley J, Coletta C, Szabo C, Rockx B, Garofalo R, Casola A
    J Virol, 2015-03-04;89(10):5557-68.
    Species: Human
    Sample Types: Cell Culture Supernates
  349. Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
    Authors: Jaguin M, Fardel O, Lecureur V
    PLoS ONE, 2015-02-24;10(2):e0116560.
    Species: Human
    Sample Types: Cell Culture Supernates
  350. BET bromodomains regulate transforming growth factor-beta-induced proliferation and cytokine release in asthmatic airway smooth muscle.
    Authors: Perry M, Durham A, Austin P, Adcock I, Chung K
    J Biol Chem, 2015-02-19;290(14):9111-21.
    Species: Human
    Sample Types: Cell Culture Supernates
  351. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
    Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
    Cell Death Differ, 2015-01-23;22(8):1313-27.
    Species: Human
    Sample Types: Cell Culture Supernates
  352. Sialylation of Helicobacter bizzozeronii lipopolysaccharides modulates Toll-like receptor (TLR) 2 mediated response.
    Authors: Kondadi P, Revez J, Hanninen M, Rossi M
    Vet Res, 2015-01-21;46(0):4.
    Species: Human
    Sample Types: Cell Culture Supernates
  353. Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
    Authors: Karmakar M, Katsnelson M, Malak H, Greene N, Howell S, Hise A, Camilli A, Kadioglu A, Dubyak G, Pearlman E
    J Immunol, 2015-01-21;194(4):1763-75.
    Species: Human
    Sample Types: Whole Cells
  354. Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
    Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
    PLoS ONE, 2015-01-15;10(1):e0116775.
    Species: Human
    Sample Types: BALF
  355. Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.
    Authors: Langjahr P, Diaz-Jimenez D, De la Fuente M, Rubio E, Golenbock D, Bronfman F, Quera R, Gonzalez M, Hermoso M
    PLoS ONE, 2014-12-22;9(12):e104624.
    Species: Human
    Sample Types: Cell Culture Supernates
  356. A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway.
    Authors: Miyamoto J, Mizukure T, Park S, Kishino S, Kimura I, Hirano K, Bergamo P, Rossi M, Suzuki T, Arita M, Ogawa J, Tanabe S
    J Biol Chem, 2014-12-10;290(5):2902-18.
    Species: Human
    Sample Types: Cell Culture Supernates
  357. Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
    Authors: Miyazaki Y, Vieira-de-Abreu A, Harris E, Shah A, Weyrich A, Castro-Faria-Neto H, Zimmerman G
    PLoS ONE, 2014-11-21;9(11):e112770.
    Species: Human
    Sample Types: Cell Culture Supernates
  358. Human intestinal epithelial cells respond to beta-glucans via Dectin-1 and Syk.
    Authors: Cohen-Kedar S, Baram L, Elad H, Brazowski E, Guzner-Gur H, Dotan I
    Eur J Immunol, 2014-10-27;44(12):3729-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  359. Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
    Authors: Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, Yang S, Chang N, Hung S, Lin Y
    PLoS ONE, 2014-07-24;9(7):e102450.
    Species: Human
    Sample Types: Cell Culture Supernates
  360. Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma.
    Authors: Green B, Wiriyachaiporn S, Grainge C, Rogers G, Kehagia V, Lau L, Carroll M, Bruce K, Howarth P
    PLoS ONE, 2014-06-23;9(6):e100645.
    Species: Human
    Sample Types: Sputum
  361. Periapical fluid RANKL and IL-8 are differentially regulated in pulpitis and apical periodontitis.
    Authors: Rechenberg D, Bostanci N, Zehnder M, Belibasakis G
    Cytokine, 2014-06-14;69(1):116-9.
    Species: Human
    Sample Types: Tissue Secretion
  362. Flagellin concentrations in expectorations from cystic fibrosis patients.
    Authors: Balloy V, Thevenot G, Bienvenu T, Morand P, Corvol H, Clement A, Ramphal R, Hubert D, Chignard M
    BMC Pulm Med, 2014-06-09;14(0):100.
    Species: Human
    Sample Types: Sputum
  363. Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.
    Authors: Labrousse D, Perret M, Hayez D, da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T
    PLoS ONE, 2014-06-06;9(6):e97546.
    Species: Human
    Sample Types: BALF
  364. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
    Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
    J Biol Chem, 2014-05-19;289(27):19231-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  365. Role of non-coding RNAs in maintaining primary airway smooth muscle cells.
    Authors: Perry, Mark M, Tsitsiou, Eleni, Austin, Philip J, Lindsay, Mark A, Gibeon, David S, Adcock, Ian M, Chung, Kian Fan
    Respir Res, 2014-05-16;15(0):58.
    Species: Human
    Sample Types: Cell Culture Supernates
  366. Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1beta-stimulated production of chemokines and matrix-degrading enzymes in vitro.
    Authors: Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borzi R, Meliconi R
    PLoS ONE, 2014-05-12;9(5):e96925.
    Species: Human
    Sample Types: Cell Culture Supernates
  367. A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
    Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
    PLoS ONE, 2014-05-09;9(5):e96943.
    Species: Human
    Sample Types: Cell Culture Supernates
  368. Chinese herbal medicine suppresses invasion-promoting capacity of cancer-associated fibroblasts in pancreatic cancer.
    Authors: Chen, Lianyu, Qu, Chao, Chen, Hao, Xu, Litao, Qi, Qi, Luo, Jianmin, Wang, Kun, Meng, Zhiqiang, Chen, Zhen, Wang, Peng, Liu, Luming
    PLoS ONE, 2014-04-29;9(4):e96177.
    Species: Human
    Sample Types: Cell Culture Supernates
  369. Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.
    Authors: O'Sullivan M, Hirota N, Martin J
    PLoS ONE, 2014-04-17;9(4):e95566.
    Species: Human
    Sample Types: Cell Culture Supernates
  370. TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans.
    Authors: Al-Kuhlani M, Rothschild J, Pal S, de la Maza L, Ouburg S, Morre S, Dean D, Ojcius D
    PLoS ONE, 2014-04-02;9(4):e93939.
    Species: Human
    Sample Types: Cell Culture Supernates
  371. The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function.
    Authors: Long H, O'Connor B, Zemans R, Zhou X, Yang I, Schwartz D
    PLoS ONE, 2014-04-02;9(4):e93550.
    Species: Human
    Sample Types: Cell Culture Supernates
  372. Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors.
    Authors: Reed, Daniel M, Foldes, Gabor, Gatheral, Timothy, Paschalaki, Koralia, Lendvai, Zsuzsann, Bagyura, Zsolt, Nemeth, Tamas, Skopal, Judit, Merkely, Bela, Telcian, Aurica G, Gogsadze, Leila, Edwards, Michael, Gough, Peter J, Bertin, John, Johnston, Sebastia, Harding, Sian E, Mitchell, Jane A
    PLoS ONE, 2014-04-01;9(4):e91119.
    Species: Human
    Sample Types: Cell Culture Supernates
  373. Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.
    Authors: Shah S, King E, Chandrasekhar A, Newton R
    J Biol Chem, 2014-04-01;289(19):13667-79.
    Species: Human
    Sample Types: Cell Culture Supernates
  374. IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells.
    Authors: Tanabe T, Shimokawaji T, Kanoh S, Rubin B
    Clin Exp Allergy, 2014-04-01;44(4):540-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  375. Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells.
    Authors: Comer D, Elborn J, Ennis M
    BMC Pulm Med, 2014-03-01;14(0):32.
    Species: Human
    Sample Types: Cell Culture Supernates
  376. Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6.
    Authors: Turner M, Cronin J, Healey G, Sheldon I
    Endocrinology, 2014-01-17;155(4):1453-65.
    Species: Bovine
    Sample Types: Cell Culture Supernates
  377. CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells.
    Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H
    Br J Haematol, 2014-01-15;165(1):134-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  378. TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
    Authors: Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P
    PLoS ONE, 2014-01-08;9(1):e84214.
    Species: Human
    Sample Types: Cell Culture Supernates
  379. Activin A as a mediator of NK-dendritic cell functional interactions.
    Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
    J Immunol, 2014-01-06;192(3):1241-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  380. Lipid-modifying enzymes in human tear fluid and corneal epithelial stress response.
    Authors: Robciuc A, Rantamaki A, Jauhiainen M, Holopainen J
    Invest Ophthalmol Vis Sci, 2014-01-02;55(1):16-24.
    Species: Human
    Sample Types: Cell Culture Supernates
  381. Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway.
    Authors: Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D
    PLoS ONE, 2013-12-30;8(12):e82867.
    Species: Human
    Sample Types: Cell Culture Supernates
  382. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.
    Authors: Shamis Y, Silva E, Hewitt K, Brudno Y, Levenberg S, Mooney D, Garlick J
    PLoS ONE, 2013-12-30;8(12):e83755.
    Species: Human
    Sample Types: Cell Culture Supernates
  383. Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
    Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
    J Immunol, 2013-12-16;192(2):722-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  384. Interleukin-8 responses of multi-layer gingival epithelia to subgingival biofilms: role of the "red complex" species.
    Authors: Belibasakis G, Thurnheer T, Bostanci N
    PLoS ONE, 2013-12-10;8(12):e81581.
  385. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
    Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
    PLoS ONE, 2013-12-10;8(12):e82734.
    Species: Human
    Sample Types: Serum
  386. A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity.
    Authors: Houser J, Komarek J, Kostlanova N, Cioci G, Varrot A, Kerr S, Lahmann M, Balloy V, Fahy J, Chignard M, Imberty A, Wimmerova M
    PLoS ONE, 2013-12-10;8(12):e83077.
    Species: Human
    Sample Types: Cell Culture Supernates
  387. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer.
    Authors: Kachroo P, Lee M, Zhang L, Baratelli F, Lee G, Srivastava M, Wang G, Walser T, Krysan K, Sharma S, Dubinett S, Lee J
    J Exp Clin Cancer Res, 2013-11-25;32(0):97.
    Species: Human
    Sample Types: Cell Culture Supernates
  388. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
    Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
    Cytokine, 2013-11-23;65(2):222-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  389. Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol.
    Authors: Kumakura S, Yamaguchi K, Sugasawa Y, Murakami T, Kikuchi T, Inada E, Nagaoka I
    Mol Med Rep, 2013-10-21;8(6):1643-8.
    Species: Human
    Sample Types: Epithelial Fluid
  390. Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate.
    Authors: Dabirian S, Taslimi Y, Zahedifard F, Gholami E, Doustdari F, Motamedirad M, Khatami S, Azadmanesh K, Nylen S, Rafati S
    PLoS Negl Trop Dis, 2013-10-17;7(10):e2491.
    Species: Human
    Sample Types: Cell Culture Supernates
  391. Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.
    Authors: Wallace A, Host A, Whitley G, Cartwright J
    Am J Pathol, 2013-10-06;183(6):1853-61.
    Species: Human
    Sample Types: Cell Culture Supernates
  392. Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.
    Authors: Hutchinson J, Rajagopal S, Yuan M, Norman J
    FASEB J, 2013-09-27;28(1):94-105.
    Species: Human
    Sample Types: Cell Culture Supernates
  393. IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others?
    Authors: Doble, Rosella, McDermott, Michael, Cesur, Ozlem, Stonehouse, Nicola J, Wittmann, Miriam
    J Invest Dermatol, 2013-09-20;134(3):852-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  394. Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity.
    Authors: Hakim A, Barnes P, Adcock I, Usmani O
    FASEB J, 2013-08-09;27(11):4510-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  395. Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
    Authors: Moh M, Lorenzini P, Gullo C, Schwarz H
    FASEB J, 2013-04-25;27(8):2957-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  396. S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
    Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
    PLoS ONE, 2013-04-24;8(4):e62372.
    Species: Human
    Sample Types: Cell Culture Supernates
  397. 1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes.
    Authors: Ding C, Wilding J, Bing C
    PLoS ONE, 2013-04-24;8(4):e61707.
    Species: Human
    Sample Types: Cell Culture Supernates
  398. Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells.
    Authors: Jeffery H, Soderberg-Naucler C, Butler L
    J Virol, 2013-03-27;87(11):6530-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  399. Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts.
    Authors: Herath T, Darveau R, Seneviratne C, Wang C, Wang Y, Jin L
    PLoS ONE, 2013-03-12;8(3):e58496.
    Species: Human
    Sample Types: Cell Culture Supernates
  400. MicroRNA-16 affects key functions of human endothelial progenitor cells.
    Authors: Goretti E, Rolland-Turner M, Leonard F, Zhang L, Wagner D, Devaux Y
    J Leukoc Biol, 2013-01-16;93(5):645-55.
    Species: Human
    Sample Types: Cell Culture Supernates
  401. Age-related changes in expression and function of Toll-like receptors in human skin.
    Authors: Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schoppl A, Tschachler E, Elbe-Burger A
    Development, 2012-10-03;139(22):4210-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  402. Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
    J Neuroinflammation, 2012-08-18;9(0):203.
    Species: Human
    Sample Types: Cell Culture Supernates
  403. Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2.
    Authors: Robciuc A, Hyotylainen T, Jauhiainen M, Holopainen J
    J Lipid Res, 2012-08-15;53(11):2286-95.
    Species: Human
    Sample Types: Cell Culture Supernates
  404. A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
    Authors: Breshears L, Schlievert P, Peterson M
    J Biol Chem, 2012-07-25;287(39):32578-87.
    Species: Human
    Sample Types: Cell Culture Supernates
  405. Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
    Eur J Clin Nutr, 2012-07-18;66(9):1072-4.
    Species: Human
    Sample Types: Plasma
  406. Milk Matters: Soluble Toll-Like Receptor 2 (sTLR2) in Breast Milk Significantly Inhibits HIV-1 Infection and Inflammation.
    Authors: Henrick BM, Nag K, Yao XD
    PLoS ONE, 2012-07-06;7(7):e40138.
    Species: Human
    Sample Types: Cell Culture Supernates
  407. Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.
    Authors: Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL
    PLoS ONE, 2012-04-24;7(4):e35866.
    Species: Human
    Sample Types: Cell Culture Supernates
  408. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012-04-18;7(4):e34965.
    Species: Human
    Sample Types: Cell Culture Supernates
  409. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
    Authors: Suh HS, Choi N, Tarassishin L, Lee SC
    PLoS ONE, 2012-04-11;7(4):e35115.
    Species: Human
    Sample Types: Cell Culture Supernates
  410. Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
    Authors: Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogne M, Moura IC, Monteiro RC
    J. Exp. Med., 2012-03-26;209(4):793-806.
    Species: Human
    Sample Types: Cell Culture Supernates
  411. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
    Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA
    Proc. Natl. Acad. Sci. U.S.A., 2012-02-06;109(8):3001-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  412. The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis.
    Authors: Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T
    Clin. Exp. Allergy, 2012-02-01;42(2):218-28.
    Species: Human
    Sample Types: Cell Culture Supernates
  413. A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer.
    Authors: Dumitru CA, Fechner MK, Hoffmann TK
    J. Leukoc. Biol., 2012-01-18;91(4):591-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  414. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
    Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
    Mucosal Immunol, 2011-12-21;5(2):140-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  415. Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells.
    Authors: Kim S, Lewis C, Nadel JA
    Exp. Cell Res., 2011-09-07;317(18):2650-60.
    Species: Human
    Sample Types: Cell Culture Supernates
  416. Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
    Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
    Blood, 2011-09-06;118(18):5031-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  417. Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways.
    Authors: Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG
    J. Immunol., 2011-01-24;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  418. Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients.
    Authors: Neuenschwander LC, Bittencourt H, Ribeiro AF, Teixeira AL, Teixeira MM, Teixeira JC, Nobre V
    Clinics (Sao Paulo), 2011-01-01;66(10):1699-705.
    Species: Human
    Sample Types: Plasma
  419. Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands.
    Authors: Ochiel DO, Ghosh M, Fahey JV
    J. Leukoc. Biol., 2010-04-12;88(3):435-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  420. IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
    Authors: Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG
    J. Immunol., 2009-12-21;184(3):1642-52.
    Species: Human
    Sample Types: Serum
  421. Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex.
    Authors: Chui JJ, Li MW, Di Girolamo N, Chang JH, McCluskey PJ, Wakefield D
    Invest. Ophthalmol. Vis. Sci., 2009-12-17;51(5):2558-67.
    Species: Human
    Sample Types: Cell Culture Supernates
  422. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
    Authors: Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM
    PLoS ONE, 2009-12-15;4(12):e8300.
    Species: Human
    Sample Types: Urine
  423. Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis.
    Authors: Rodland EK, Ueland T, Pedersen TM, Halvorsen B, Muller F, Aukrust P, Froland SS
    Infect. Immun., 2009-12-14;78(3):1269-75.
    Species: Human
    Sample Types: Cell Culture Supernates
  424. Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.
    Authors: Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB
    J. Immunol., 2009-11-04;183(11):6989-97.
    Species: Human
    Sample Types: Cell Culture Supernates
  425. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression.
    Authors: Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K
    Eur. J. Immunol., 2009-10-01;39(10):2779-88.
    Species: Human
    Sample Types: Cell Culture Supernates
  426. Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder.
    Authors: Brietzke E, Kauer-Sant'Anna M, Teixeira AL, Kapczinski F
    Brain Behav. Immun., 2009-05-04;23(8):1079-82.
    Species: Human
    Sample Types: Serum
  427. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009-03-02;119(10):1424-32.
    Species: Human
    Sample Types: Cell Culture Supernates
  428. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  429. Carbon dioxide inhalation causes pulmonary inflammation.
    Authors: Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco AJ, Schwartz L
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-01-09;296(4):L657-65.
    Species: Human
    Sample Types: Cell Culture Supernates
  430. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2008-12-03;123(1):179-86.
    Species: Human
    Sample Types: Cell Culture Supernates
  431. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008-06-17;112(5):1822-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  432. Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
    Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
    J. Immunol., 2008-05-01;180(9):6000-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  433. Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
    Authors: Lemarie A, Bourdonnay E, Morzadec C, Fardel O, Vernhet L
    J. Immunol., 2008-05-01;180(9):6010-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  434. Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes.
    Authors: Weigert J, Neumeier M, Wanninger J, Wurm S, Kopp A, Schober F, Filarsky M, Schaffler A, Zeitoun M, Aslanidis C, Buechler C
    FEBS Lett., 2008-04-28;582(12):1777-82.
    Species: Human
    Sample Types: Cell Culture Supernates
  435. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
    Authors: Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M
    FASEB J., 2008-03-25;22(8):2747-57.
    Species: Human
    Sample Types: Cell Culture Supernates
  436. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
    Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
    J. Cell. Physiol., 2008-01-01;214(1):27-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  437. Respiratory effects of exposure to diesel traffic in persons with asthma.
    Authors: McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, Harrington R, Svartengren M, Han IK, Ohman-Strickland P, Chung KF, Zhang J
    N. Engl. J. Med., 2007-12-06;357(23):2348-58.
    Species: Human
    Sample Types: Sputum
  438. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007-12-01;117(12):3664-3672.
    Species: Human
    Sample Types: Cell Culture Supernates
  439. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
    Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
    J. Biol. Chem., 2007-08-31;282(44):31882-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  440. Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.
    Authors: Yamasaki K, Di Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian A, Morhenn VB, Gallo RL
    Nat. Med., 2007-08-05;13(8):975-80.
    Species: Human
    Sample Types: Cell Culture Supernates
  441. Airway remodelling in children with cystic fibrosis.
    Authors: Hilliard TN, Regamey N, Shute JK, Nicholson AG, Alton EW, Bush A, Davies JC
    Thorax, 2007-05-25;62(12):1074-80.
    Species: Human
    Sample Types: BALF
  442. Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling.
    Authors: Muselet-Charlier C, Roque T, Boncoeur E, Chadelat K, Clement A, Jacquot J, Tabary O
    Biochem. Biophys. Res. Commun., 2007-04-02;357(2):402-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  443. Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro.
    Authors: Potapova IA, Gaudette GR, Brink PR, Robinson RB, Rosen MR, Cohen IS, Doronin SV
    Stem Cells, 2007-03-29;25(7):1761-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  444. A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.
    Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL
    Biochem. Pharmacol., 2007-03-12;73(12):1957-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  445. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007-02-15;178(4):2229-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  446. Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures.
    Authors: Sawant KV, McMurray DN
    Infect. Immun., 2007-02-05;75(4):1870-7.
    Species: Guinea Pig
    Sample Types: Cell Culture Supernates
  447. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.
    Authors: Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006-10-13;292(2):L567-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  448. Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle.
    Authors: Sukkar MB, Xie S, Khorasani NM, Kon OM, Stanbridge R, Issa R, Chung KF
    J. Allergy Clin. Immunol., 2006-07-03;118(3):641-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  449. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
    Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
    J. Pharmacol. Exp. Ther., 2006-05-11;318(2):741-50.
    Species: Human
    Sample Types: Cell Culture Supernates
  450. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006-03-15;176(6):3742-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  451. Development of a guinea pig immune response-related microarray and its use to define the host response following Mycobacterium bovis BCG vaccination.
    Authors: Tree JA, Elmore MJ, Javed S, Williams A, Marsh PD
    Infect. Immun., 2006-02-01;74(2):1436-41.
    Species: Guinea Pig
    Sample Types: Cell Culture Supernates
  452. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
    Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
    Eur. J. Immunol., 2005-08-01;35(8):2459-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  453. NF-kappaB in tracheal lavage fluid from intubated premature infants: association with inflammation, oxygen, and outcome.
    Authors: Bourbia A, Cruz MA, Rozycki HJ
    Arch. Dis. Child. Fetal Neonatal Ed., 2005-07-27;91(1):F36-9.
    Species: Human
    Sample Types: Tracheal Lavage Fluid
  454. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
    Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
    J. Immunol., 2004-07-15;173(2):1463-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  455. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004-03-25;104(2):314-20.
    Species: Human
    Sample Types: Cell Culture Supernates
  456. Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk.
    Authors: LeBouder E, Rey-Nores J, Rushmere N, Grigorov M, Lawn S, Affolter M, Griffin G, Ferrara P, Schiffrin E, Morgan B, Labeta M
    J Immunol, 2003-12-15;171(12):6680-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  457. Urinary interleukin-8 predicts the response of standard and low dose intravesical bacillus Calmette-Guerin (modified Danish 1331 strain) for superficial bladder cancer.
    Authors: Kumar A, Dubey D, Bansal P, Mandhani A, Naik S
    J. Urol., 2002-11-01;168(5):2232-5.
    Species: Human
    Sample Types: Urine
  458. Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosis.
    Authors: Lyons MJ, Yoshimura T, McMurray DN
    Infect. Immun., 2002-10-01;70(10):5471-8.
    Species: Guinea Pig
    Sample Types: Cell Culture Supernates

FAQs

  1. Is PBS a suitable alternative with which to formulate the Reagent Diluent?

    • Our lab has determined that Tris-buffered saline generates optimal assay performance in comparison to PBS for this assay. This assay is validated with Reagent Diluent formulated using Tris-buffered saline.

View all ELISA FAQs
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Reviews for Human IL-8/CXCL8 DuoSet ELISA

Average Rating: 4.7 (Based on 26 Reviews)

5 Star
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3 Star
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Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 09/25/2024
Sample Tested: Cell culture supernatant
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 09/12/2024
Sample Tested: Blood mononuclear cells (PBMCs)
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 12/13/2021
Sample Tested: Plasma

Good results in plasma. Used neat and 1:5.

Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 11/30/2021
Sample Tested: Serum-free Cell Culture Supernates
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 04/29/2021
Sample Tested: Cell culture supernatant
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 01/27/2021
Sample Tested: Cell culture supernatant
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 10/16/2020
Sample Tested: K562 human chronic myelogenous leukemia cell line
Human IL-8/CXCL8 DuoSet ELISA
By Andy liu on 10/05/2020
Sample Tested: Serum
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 05/01/2020
Sample Tested: Primary airway epithelial cells
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 04/02/2020
Sample Tested: Serum and Plasma

We used this kit for the quantification of IL-8 in human serum and plasma. We could not see any signals. Nevertheless, well-explained protocol.

Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 01/25/2020
Sample Tested: Cell Culture Media
Human IL-8/CXCL8 DuoSet ELISA
By sothy yi on 12/11/2019
Sample Tested: human whole blood
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 09/14/2019
Sample Tested: HUVEC human umbilical vein endothelial cells

Total Cell Protein

Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 09/07/2019
Sample Tested: Cell culture supernatant,Stimulated Human Bronchial Epithelial Cell Line (BEAS-2B)
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 08/01/2019
Sample Tested: Tissue Culture Media
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Sophie Millar on 01/16/2019
Sample Tested: Cell Culture Media
Human IL-8/CXCL8 DuoSet ELISA DY208
Human IL-8/CXCL8 DuoSet ELISA
By Ivan Luzardo on 01/03/2019
Sample Tested: Cell Lysates
Human IL-8/CXCL8 DuoSet ELISA
By Leslie Priddy on 03/30/2018
Sample Tested: Serum
Human IL-8/CXCL8 DuoSet ELISA
By Balaji Mahender on 01/18/2018
Sample Tested: Citrate Plasma,EDTA Plasma,Heparin Plasma
Human IL-8/CXCL8 DuoSet ELISA
By Anonymous on 08/02/2017
Sample Tested: Serum and Plasma
Human IL-8/CXCL8 DuoSet ELISA DY208
Human CXCL8/IL-8 DuoSet ELISA
By Anonymous on 08/19/2016
Sample Tested: HUVEC human umbilical vein endothelial cells
Human CXCL8/IL-8 DuoSet ELISA DY208
Human CXCL8/IL-8 DuoSet ELISA
By sothy yi on 08/02/2016
Sample Tested: THP-1 human acute monocytic leukemia cell line
Human CXCL8/IL-8 DuoSet ELISA DY208
Human CXCL8/IL-8 DuoSet ELISA
By Ahmad Al-Attar on 06/24/2016
Sample Tested: Cell culture supernatant

I would recommend using R&D's ancillary kit reagents.

Human CXCL8/IL-8 DuoSet ELISA DY208
Human CXCL8/IL-8 DuoSet ELISA
By Anonymous on 06/02/2016
Sample Tested: HUVEC human umbilical vein endothelial cells

Very nice IL8 detection in HUVEC cells treated with pro-inflammatory stimuli. Slightly higher background in untreated cells than expected, but not overly problematic. Would definitely publish and use again.

Human CXCL8/IL-8 DuoSet ELISA DY208
Human CXCL8/IL-8 DuoSet ELISA
By Yu Sun on 05/24/2016
Sample Tested: Human cell conditioned medium
Human CXCL8/IL-8 DuoSet ELISA, 15 Plate
By Yanhan Wang on 02/25/2016
Sample Tested: NHEK human normal epidermal keratinocytes
Human CXCL8/IL-8 DuoSet ELISA, 15 Plate DY208