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Human CD37 Antibody

Catalog #: MAB4625
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB4625
MAB4625-SP
Detection of CD37 in Human Monocytes by Flow Cytometry.
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Citations (1)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CD37 Antibody Summary

Species Reactivity
Human
Specificity
Detects human CD37. Stains human CD37 transfectants but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2A Clone # 424925
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD37
Accession # Q96LM7
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25 µg/106 cells
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CD37 antibody in Human Monocytes antibody by Flow Cytometry. View Larger

Detection of CD37 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human CD37 Monoclonal Antibody (Catalog # MAB4625, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0102B). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD37

CD37, also known as TSPAN26, is a 40‑45 kDa palmitoylated tetraspanin superfamily glycoprotein that is expressed by lymphocytes and myeloid cells. CD37 directly associates with dectin-1 on macrophages and stabilizes cell surface dectin-1 expression. It also inhibits T cell activation and proliferation by limiting T cell receptor signaling. Human CD37 shares 80% aa sequence identity with mouse and rat CD37.

Entrez Gene IDs
951 (Human); 12493 (Mouse); 29185 (Rat)
Alternate Names
CD37 antigentetraspanin-26; CD37 molecule; CD37; cell differentiation antigen 37; GP52-40; leukocyte antigen CD37; MGC120234; Tetraspanin-26; TSPAN26; tspan-26; TSPAN26leukocyte surface antigen CD37

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Citation for Human CD37 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Potentials and capabilities of the Extracellular Vesicle (EV) Array.
    Authors: Jorgensen MM, Baek R, Varming K.
    J Extracell Vesicles

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