Home / EPAC Inhibitors / HJC 0350

HJC 0350

Catalog #: 4844
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4844/10
4844/50
HJC 0350 | CAS No. 885434-70-8 | EPAC Inhibitors
1 Image
Description: Selective Epac2 inhibitor

Chemical Name: 2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole

Purity: ≥98%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

HJC 0350 is a selective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.

Technical Data

M.Wt:
277.38
Formula:
C15H19NO2S
Solubility:
Soluble to 50 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
885434-70-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for HJC 0350

The citations listed below are publications that use Tocris products. Selected citations for HJC 0350 include:

2 Citations: Showing 1 - 2

  1. Regulation of Mitochondrial Function by Epac2 Contributes to Acute Inflammatory Hyperalgesia.
    Authors: Derek C Et al.
    J Neurosci  2021;41:2883-2898
  2. The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability.
    Authors: Cheng-Mao Et al.
    J Biol Chem  2018;293:717-730

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for HJC 0350

There are currently no reviews for this product. Be the first to review HJC 0350 and earn rewards!

Have you used HJC 0350?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.