FFN 102 mesylate
Chemical Name: 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
Purity: ≥99%
Biological Activity
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain.
Rodriguez et al.
Proc.Natl.Acad.Sci.U.S.A., 2013;110:870 -
Visualizing neurotransmitter secretion at individual synapses.
Sames et al.
ACS Chem.Neurosci., 2013;4:648 -
Development of pH-responsive fluorescent false neurotransmitters.
Lee et al.
J.Am.Chem.Soc., 2010;132:8828
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