dTAG-13-NEG

Catalog #: 6916 Datasheet / COA / SDS

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6916/5

dTAG-13-NEG | CAS No. 2451573-90-1 | TAG Degradation Platforms

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Description: Negative control for dTAG-13 (Cat. No. 6605)

Chemical Name: 1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2S)-2-piperidinecarboxylate (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester

Purity: ≥97%

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Biological Activity

dTAG-13-NEG is a negative control for dTAG-13 (Cat. No. 6605).

Technical Data

M.Wt:

1063.19

Formula:

C₅₈H₇₀N₄O₁₅

Solubility:

Soluble to 100 mM in DMSO and to 20 mM in ethanol

Purity:

≥97%

Storage:

Store at -20°C

CAS No:

2451573-90-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:

Sold under license from Dana-Farber Cancer Institute

Background References

The dTAG system for immediate and target-specific protein degradation.
Nabet et al.
Nat.Chem.Biol., 2018;14:431
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules.
Nabet et al.
Nat.Commun., 2020;11:4687

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