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DREADD agonist 21 dihydrochloride

Catalog #: 6422
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6422/50
6422/10
DREADD agonist 21 dihydrochloride | CAS No. 2250025-92-2 | DREADD Activators
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Description: Potent hM3Dq and hM4Di DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
Alternative Names: Compound 21 (water-soluble)

Chemical Name: 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride

Purity: ≥98%

Product Details
Citations (5)
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Biological Activity

DREADD agonist 21 dihydrochloride is a water soluble version of DREADD agonist 21 (Cat. No. 5548). Potent muscarinic DREADD agonist.

Technical Data

M.Wt:
351.27
Formula:
C17H18N4.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
2250025-92-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for DREADD agonist 21 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for DREADD agonist 21 dihydrochloride include:

5 Citations: Showing 1 - 5

  1. Medial and dorsal lateral septum involving social disruption stress-primed escalation in acid-induced writhes.
    Authors: Lung Et al.
    Front Mol Neurosci  2023;16:1158525
  2. Activation of basolateral amygdala to anterior cingulate cortex circuit alleviates MK-801 induced social and cognitive deficits of schizophrenia.
    Authors: Xin Et al.
    Front Cell Neurosci  2023;16:1070015
  3. Neural activity in the mouse claustrum in a cross-modal sensory selection task.
    Authors: Su-Jeong Et al.
    Neuron  2022;110:486-501.e7
  4. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.
    Authors: Nizar N Et al.
    Cell Host Microbe  2020;27:614-628.e6
  5. Estimation of Current and Future Physiological States in Insular Cortex.
    Authors: Mark L Et al.
    Neuron  2020;105:1094-1111.e10

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