DIM-C-pPhOH

Catalog # Availability Size / Price Qty
6377/25
6377/5
DIM-C-pPhOH | CAS No. 151358-47-3 | Additional Nuclear Receptor Compounds
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Description: Nur77 antagonist

Chemical Name: 1,1-Bis(3'-indolyl)-1-(p-hydroxyphenyl)methane

Purity: ≥98%

Product Details
Reviews

Biological Activity

DIM-C-pPhOH is a Nur77 (NR4A1) antagonist. Inhibits TGF-β induced cell migration of breast cancer cell lines. Promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines. Mimics effects of Nur77 RNAi silencing.

Technical Data

M.Wt:
338.408
Formula:
C23H18N2O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
151358-47-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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