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CST 530

Catalog #: 8065 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8065/10
CST 530 | CAS No. 847137-53-5 | IAP Inhibitors
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Description: Monovalent IAP antagonist

Chemical Name: (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-phenoxy-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide

Purity: ≥97%

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Biological Activity

CST 530 is a monovalent IAP antagonist. Induces cIAP1 and cIAP2 autodegradation in MM.1S cells (degrades cIAP1 at 0.1μM and cIAP2 at 1μM, after 16h). CST 530 reduces cell viability in a variety of cancer cell lines including SUDHL6, MOLM13 and HEL (IC50 values are 170 nM, 420 nM and 450 nM respectively).

Technical Data

M.Wt:
560.74
Formula:
C33H44N4O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
847137-53-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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