CometAssay Lysis Solution
CometAssay Lysis Solution Summary
CometAssay Lysis Solution contains high salt and detergent and is suitable for use with either the alkaline or neutral comet assay protocol.Available as 100 mL or 1000 mL (2 x 500 mL) volumes.
Key Benefits
• Designed for use with CometAssay, FLARE, and CometChip.
Specifications
Limitations
For research use only. Not for diagnostic use.
Product Datasheets
Citations for CometAssay Lysis Solution
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Temporal coordination of the transcription factor response to H2O2 stress
Authors: Jose, E;March-Steinman, W;Wilson, BA;Shanks, L;Parkinson, C;Alvarado-Cruz, I;Sweasy, JB;Paek, AL;
Nature communications 2024-04-23
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Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial epithelial cells
Authors: Meaza, I;Williams, AR;Lu, H;Kouokam, JC;Toyoda, JH;Croom-Perez, TJ;Wise, SS;Aboueissa, AE;Wise, JP;
Toxicology and applied pharmacology 2023-10-05
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Frailty, Sex, and Poverty are Associated with DNA Damage and Repair in Frail, Middle-aged Urban Adults
Authors: Smith, J;Hooten, N;Mode, N;Zonderman, A;Ezike, N;Kaushal, S;Evans, M;
DNA Repair 2023-06-29
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Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding
Authors: Shimizu, N;Hamada, Y;Morozumi, R;Yamamoto, J;Iwai, S;Sugiyama, KI;Ide, H;Tsuda, M;
The Journal of biological chemistry 2023-06-29
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Cellular photo(geno)toxicity of gefitinib after biotransformation
Authors: El Ouardi, M;Tamarit, L;Vayá, I;Miranda, MA;Andreu, I;
Frontiers in pharmacology 2023-06-07
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PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity
Authors: Kim, S;Kim, Y;Kim, Y;Yoon, S;Lee, KY;Lee, Y;Kang, S;Myung, K;Oh, CK;
PloS one 2023-05-19
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NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
Authors: A Meroni, J Grosser, S Agashe, N Ramakrishn, J Jackson, P Verma, L Baranello, A Vindigni
Science Advances, 2022-12-09;8(49):eabq0648. 2022-12-09
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Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinoma
Authors: CY Hsieh, WC Chang, CC Lin, JH Chen, CY Lin, CH Liu, C Lin, MC Hung
American journal of cancer research, 2022-11-15;12(11):5049-5061. 2022-11-15
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The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
Authors: M Yoshinaga, K Han, DW Morgens, T Horii, R Kobayashi, T Tsuruyama, F Hia, S Yasukura, A Kajiya, T Cai, PHC Cruz, A Vandenbon, Y Suzuki, Y Kawahara, I Hatada, MC Bassik, O Takeuchi
Nature Communications, 2022-10-28;13(1):6435. 2022-10-28
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Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
Authors: J Li, CA Koczor, KM Saville, F Hayat, A Beiser, S McClellan, ME Migaud, RW Sobol
Cancers, 2022-07-22;14(15):. 2022-07-22
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Oxidative Stress and Deregulated DNA Damage Response Network in Lung Cancer Patients
Authors: DT Stefanou, M Kouvela, D Stellas, K Voutetakis, O Papadodima, K Syrigos, VL Souliotis
Biomedicines, 2022-05-26;10(6):. 2022-05-26
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Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor
Authors: B Jiang, C Murray, BL Cole, JNM Glover, GK Chan, J Deschenes, RS Mani, S Subedi, JD Nerva, AC Wang, CM Lockwood, HC Mefford, SES Leary, JG Ojemann, M Weinfeld, CI Ene
Scientific Reports, 2022-03-30;12(1):5386. 2022-03-30
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Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents
Authors: FB Rashed, D Diaz-Dussa, F Mashayekhi, D Macdonald, PN Nation, XH Yang, S Sokhi, AC Stoica, H El-Saidi, C Ricardo, R Narain, IH Ismail, LI Wiebe, P Kumar, M Weinfeld
Redox Biology, 2022-03-21;52(0):102300. 2022-03-21
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Evaluation of phototoxicity induced by the anticancer drug rucaparib
Authors: A Mateos-Puj, MC Jiménez, I Andreu
Scientific Reports, 2022-03-02;12(1):3434. 2022-03-02
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Performance Evaluation for Repair of HSGc-C5 Carcinoma Cell Using Geant4-DNA
Authors: D Sakata, M Suzuki, R Hirayama, Y Abe, M Muramatsu, S Sato, O Belov, I Kyriakou, D Emfietzogl, S Guatelli, S Incerti, T Inaniwa
Cancers, 2021-11-30;13(23):. 2021-11-30
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Genetic vulnerabilities upon inhibition of DNA damage response
Authors: C Wang, M Tang, Z Chen, L Nie, S Li, Y Xiong, KA Szymonowic, JM Park, H Zhang, X Feng, M Huang, D Su, T Hart, J Chen
Nucleic Acids Research, 2021-08-20;0(0):. 2021-08-20
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Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage
Authors: X Wu, B Wang
Nature Communications, 2021-07-16;12(1):4373. 2021-07-16
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DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation
Authors: W Ren, H Fan, SA Grimm, JJ Kim, L Li, Y Guo, CJ Petell, XF Tan, ZM Zhang, JP Coan, J Yin, DI Kim, L Gao, L Cai, N Khudaverdy, B Çetin, DJ Patel, Y Wang, Q Cui, BD Strahl, O Gozani, KM Miller, SE O'Leary, PA Wade, GG Wang, J Song
Nature Communications, 2021-05-03;12(1):2490. 2021-05-03
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Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors
Authors: E Grimley, AJ Cole, TT Luong, SC McGonigal, S Sinno, D Yang, KA Bernstein, RJ Buckanovic
Theranostics, 2021-01-20;11(8):3540-3551. 2021-01-20
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Super-resolution visualization of distinct stalled and broken replication fork structures
Authors: DR Whelan, WTC Lee, F Marks, YT Kong, Y Yin, E Rothenberg
PloS Genetics, 2020-12-28;16(12):e1009256. 2020-12-28
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Fanconi Anemia Pathway Activation by FOXM1 Is Critical to Bladder Cancer Recurrence and Anticancer Drug Resistance
Authors: YG Roh, JY Mun, SK Kim, W Park, MS Jeong, TN Kim, WT Kim, YH Choi, IS Chu, SH Leem
Cancers (Basel), 2020-05-30;12(6):. 2020-05-30
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Photomutagenicity of chlorpromazine and its N-demethylated metabolites assessed by NGS
Authors: JAG Agúndez, E García-Mar, G García-Lai, MA Miranda, I Andreu
Sci Rep, 2020-04-23;10(1):6879. 2020-04-23
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A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells
Authors: M Wakita, A Takahashi, O Sano, TM Loo, Y Imai, M Narukawa, H Iwata, T Matsudaira, S Kawamoto, N Ohtani, T Yoshimori, E Hara
Nat Commun, 2020-04-22;11(1):1935. 2020-04-22
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Karyopherin &alpha-2 Mediates MDC1 Nuclear Import through a Functional Nuclear Localization Signal in the tBRCT Domain of MDC1
Authors: K Radhakrish, SJ Park, SW Kim, G Hariharasu, SY Jeong, IY Chang, JH Lee
Int J Mol Sci, 2020-04-10;21(7):. 2020-04-10
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Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition
Authors: FA Alhumaydhi, D de O Lopes, DL Bordin, ASM Aljohani, CB Lloyd, MD McNicholas, L Milano, CF Charlier, I Villela, JAP Henriques, KE Plant, RM Elliott, LB Meira
Sci Rep, 2020-02-10;10(1):2209. 2020-02-10
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Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
Authors: X Meng, Y Zhao, B Han, C Zha, Y Zhang, Z Li, P Wu, T Qi, C Jiang, Y Liu, J Cai
Nat Commun, 2020-01-30;11(1):594. 2020-01-30
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Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro
Authors: KJ Nytko, P Thumser-He, MS Weyland, S Scheidegge, CR Bley
PLoS ONE, 2019-05-15;14(5):e0216744. 2019-05-15
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CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs
Authors: M Mohiuddin, MM Rahman, JE Sale, CE Pearson
Nucleic Acids Res., 2019-04-08;0(0):. 2019-04-08
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Marginal Zinc Deficiency and Environmentally Relevant Concentrations of Arsenic Elicit Combined Effects on the Gut Microbiome
Authors: CA Gaulke, J Rolshoven, CP Wong, LG Hudson, E Ho, TJ Sharpton
mSphere, 2018-12-05;3(6):. 2018-12-05
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Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles
Authors: P Sykora, Y Chiari, A Heaton, N Moreno, S Glaberman, RW Sobol
Environ. Mol. Mutagen., 2018-03-14;0(0):. 2018-03-14
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Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture.
Authors: Liu F, Patterson T, Sadovova N, Zhang X, Liu S, Zou X, Hanig J, Paule M, Slikker W, Wang C
Toxicol Sci, 2012-10-11;131(2):548-57. 2012-10-11
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Radioprotective properties of tocopherol succinate against ionizing radiation in mice.
Authors: Singh V, Singh P, Wise S, Posarac A, Fatanmi O
J Radiat Res, 2012-10-03;54(2):210-20. 2012-10-03
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Nongenotoxic apoptosis inducers do not produce misleading positive results in the TK6 cell-based GADD45a-GFP genotoxicity assay.
Authors: Topham C, Billinton N, Walmsley R
Toxicol Sci, 2012-04-05;128(1):79-91. 2012-04-05
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Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors.
Authors: Lee J, Choy M, Ngo L, Venta-Perez G, Marks P
Proc Natl Acad Sci U S A, 2011-11-21;108(49):19629-34. 2011-11-21
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