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BTZO 1

Catalog #: 4204 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4204/10
4204/50
BTZO 1 | CAS No. 99420-15-2 | Cytokine Compounds
1 Image
Description: MIF binder

Chemical Name: 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one

Purity: ≥99%

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Biological Activity

BTZO 1 binds macrophage migration inhibitory factor (MIF; Kd = 68.6 nM) and activates antioxidant response element (ARE)-mediated gene expression. BTZO 1 suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro and is cardioprotective.

External Portal Information

Chemicalprobes.org and the Chemical Probes webpages of the Structural Genomics Consortium are portals that offer independent guidance on the selection and/or application of small molecules for research. The use of BTZO 1 is reviewed on chemicalprobes.org and the SGC website.

Technical Data

M.Wt:
240.28
Formula:
C13H8N2OS
Solubility:
Soluble to 20 mM in DMSO with gentle warming
Purity:
≥99%
Storage:
Store at RT
CAS No:
99420-15-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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