Bradykinin

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Endothelial nitric-oxide synthase activation generates an inducible nitric-oxide synthase-like output of nitric oxide in inflamed endothelium.
   Lowry J, Brovkovych V, Zhang Y, Skidgel R
   J Biol Chem, 2013;288(6):4174-93.
2. The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney
   
   PLoS Pathog., 2016;12(11):e1005952.
3. Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection
   K Ramani, CV Jawale, AH Verma, BM Coleman, JK Kolls, PS Biswas
   JCI Insight, 2018;3(9):.
4. IL-17 Receptor Signaling Negatively Regulates the Development of Tubulointerstitial Fibrosis in the Kidney
   K Ramani, RJ Tan, D Zhou, BM Coleman, CV Jawale, Y Liu, PS Biswas
   Mediators Inflamm., 2018;2018(0):5103672.
5. Bradykinin receptors and their antagonists.
   Regoli et al.
   Eur.J.Pharmacol., 1998;348:1
6. International union of pharmacology XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences.
   Leeb-Lundberg et al.
   Pharmacol.Rev., 2005;57:27
7. Peptide and non-peptide bradykinin receptor antagonists: role in allergic airway disease
   Abraham et al.
   Eur.J.Pharmacol., 2006;533:215

Product Datasheets