Home / Fluorescent Integrins Probes / BOP-JF646

BOP-JF646

Catalog #: 6997 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6997/100U
BOP-JF646 | Fluorescent Integrins Probes
2 Images
Description: Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 646; fluorogenic; photostable

Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-5-(((1-((3R,5S)-5-(((S)-1-carboxy-2-(4-((pyrrolidine-1-carbonyl)oxy)phenyl)ethyl)carbamoyl)-1-(phenylsulfonyl)pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)benzoate

Purity: ≥90%

Product Details
Reviews
Biological Activity Scientific Data Technical Data Product Datasheets Calculators

Biological Activity

BOP-JF646 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP (Cat. No. 6047) conjugated to Janelia Fluor® 646 (Cat. No. 6148). Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 655 nm; emission maximum = 672 nm.

Scientific Data

N/A Application of BOP-JF549 View Larger

Application of BOP-JF549 in Immortalized Human Keratinocyte Cells. Immortalized human keratinocytes expressing a GFP-tagged alpha 4 integrin were incubated with 10 μm BOP-Janelia Fluor® 568. Cells were incubated at 37°C and imaged using Nikon A1R confocal microscope. Scale bar = 10 μm.Image kindly provided by Willow Hight-Warburton; Kings College London.

Optical Data for BOP-JF646

BOP-JF646 Dye Spectra
Emission Color Red
Brightness
λabs 655 nm
λem 672 nm
Closest Laser line 647 nm
Application Flow Cytometry, Confocal Microscopy, Super Resolution Microscopy (SRM)

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

Technical Data

M.Wt:
1090.3
Formula:
C57H59N9O10SSi
Purity:
≥90%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for BOP-JF646

There are currently no reviews for this product. Be the first to review BOP-JF646 and earn rewards!

Have you used BOP-JF646?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.