β-Estradiol

Catalog #: 2824
5 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
2824/100

β-Estradiol | CAS No. 50-28-2 | Estrogen and Related Receptor Agonists

1 Image

Description: Endogenous ER agonist

Alternative Names: 17 β-Estradiol

Chemical Name: (17β)-Estra-1,3,5(10)-triene-3,17-diol

Purity: ≥99%

View All Products for Estrogen and Related Receptor Agonists

Product Details

Citations (5)

Reviews

Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

β-Estradiol is an endogenous estrogen receptor (ER) agonist (K_i values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.

α-Estradiol also available.

Technical Data

M.Wt:

272.38

Formula:

C₁₈H₂₄O₂

Solubility:

Soluble to 100 mM in DMSO and to 75 mM in ethanol with gentle warming

Purity:

≥99%

Storage:

Store at RT

CAS No:

50-28-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.
Thomas et al.
Endocrinology, 2005;146:624
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β.
Kuiper et al.
Endocrinology, 1997;138:863

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Estradiol 17B, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

Citations for β-Estradiol

The citations listed below are publications that use Tocris products. Selected citations for β-Estradiol include:

5 Citations: Showing 1 - 5

A mechanical acupuncture instrument mitigates the endoplasmic reticulum stress and oxidative stress of ovariectomized rats.
Authors: Seo Et al.
Integr Med Res 2019;8:187
Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro.
Authors: Al-Khyatt
BMC?Cancer 2018;18(1):121
Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells.
Authors: Pastore Et al.
Biol Reprod 2016;94:139
Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Mediated Redox Signaling and Vascular Remodeling by 16α-Hydroxyestrone in Human Pulmonary Artery Cells: Implications in Pulmonary Arterial Hypertension.
Authors: Hood Et al.
Hypertension 2016;68:796
p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.
Authors: Leal Et al.
PLoS One 2012;7:e49817

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for β-Estradiol

There are currently no reviews for this product. Be the first to review β-Estradiol and earn rewards!

Have you used β-Estradiol?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.