ANR 94
Chemical Name: 8-Ethoxy-9-ethyl-9H-purin-6-amine
Purity: ≥99%
Biological Activity
ANR 94 is an adenosine A2A receptor (AA2AR) antagonist (Ki values are 643 and 46 nM for rat and human AA2ARs respectively). Most active AA2AR antagonist for human receptors. Displays activity in the treatment of Parkinson's disease in vivo; improves parkinsonian motor deficits and tremors. Exhibits neuroprotective and anti-inflammatory effects.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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A new ethyladenine antagonist of adenosine A2A receptors: Behavioral and biochemical characterization as an antiparkinsonian drug.
Pinna et al.
Neuropharmacology, 2010;58:613
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Citation for ANR 94
The citations listed below are publications that use Tocris products. Selected citations for ANR 94 include:
1 Citation: Showing 1 - 1
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Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells.
Authors: Schneider Et al.
Circulation 2015;14:201
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