Angiotensin II
Purity: ≥95%
Biological Activity
Angiotensin II is a endogenous potent vasoconstrictor peptide; endogenous substrate for ACE2. Stimulates the synthesis and release of aldosterone.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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MicroRNA?219 overexpression serves a protective role during liver fibrosis by targeting tumor growth factor ? receptor 2
L Ma, J Ma, HL Ou
Mol Med Rep, 2018;0(0):. -
Effects of prostaglandins and nitric oxide on the renal effects of angiotensin II in the anaesthetised rat.
Clayton et al.
Br.J.Pharmacol., 1998;124:1467 -
Activation of brain neurons by circulating angiotensin II: direct effects and baroreceptor-mediated secondary effects.
Potts et al.
Neuroscience, 1999;90:581 -
Cardiovascular effects of microinjection of angiotensin II in the brainstem of renal hypertensive rats.
Mosequeda-Garcia et al.
J.Pharmacol.Exp.Ther., 1990;255:374 -
Ca2+/calmodulin kinase II-dependent regulation of &betaIV-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility
DM Nassal, NJ Patel, SD Unudurthi, R Shaheen, J Yu, PJ Mohler, TJ Hund
The Journal of Biological Chemistry, 2021;0(0):100893.
Product Datasheets
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Citations for Angiotensin II
The citations listed below are publications that use Tocris products. Selected citations for Angiotensin II include:
10 Citations: Showing 1 - 10
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Ghrelin's effects on food motivation in rats are not limited to palatable foods.
Authors: Bake Et al.
J Neuroendocrinol 2018;:e12665
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Nogo-C regulates post myocardial infarction fibrosis through the interaction with ER Ca2+ leakage channel Sec61? in mouse hearts.
Authors: Weng
Cell Death Dis 2018;9:612
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Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy.
Authors: Zheng Et al.
Front Pharmacol 2017;8:222
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Acute ghrelin changes food preference from a high-fat diet to chow during binge-like eating in rodents.
Authors: Bake Et al.
J Neuroendocrinol 2017;29
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Central administration of ghrelin induces conditioned avoidance in rodents.
Authors: Schéle Et al.
Eur Neuropsychopharmacol 2017;27:809
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Acute Metabolic Effects of olanz. Depend on Dose and Injection Site.
Authors: Klingerman Et al.
Dose Response 2016;13:1559325815618910
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The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells.
Authors: Rodrigues-Diez Et al.
Hum Mol Genet 2015;22:29
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PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues.
Authors: Felizola Et al.
Proc Natl Acad Sci U S A 2014;52:159
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Differential effects of alendr. and los. therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.
Authors: Nistala Et al.
J Mol Endocrinol 2010;19:4790
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Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity.
Authors: Vinciguerra Et al.
Aging (Albany NY) 2009;2:43
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