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(±)-Anatoxin A fumarate

Catalog #: 0789
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0789/1
(±)-Anatoxin A fumarate | CAS No. 1219922-30-1 | Additional Nicotinic Receptor Agonists
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Description: nAChR agonist

Chemical Name: (±)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate

Purity: ≥96%

Product Details
Citations (1)
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Biological Activity

(±)-Anatoxin A fumarate is a potent nicotinic agonist (Ki values are 1.25 and 1840 nM for α4β2 and α7 nicotinic receptors respectively). (�)-Anatoxin A fumarate stimulates [3H]-dopamine release from rat striatal synaptosomes (EC50 = 136 nM). (�)-Anatoxin A fumarate induces apoptosis in rat thymocytes and Vero cells by generation of reactive oxygen species and caspase activation.

Technical Data

M.Wt:
281.31
Formula:
C10H15NO.C4H4O4
Solubility:
Soluble to 100 mM in water
Purity:
≥96%
Storage:
Store at +4°C
CAS No:
1219922-30-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for (±)-Anatoxin A fumarate

The citations listed below are publications that use Tocris products. Selected citations for (±)-Anatoxin A fumarate include:

1 Citation: Showing 1 - 1

  1. Effect of nitrogen on cellular production and release of the neurotoxin anatoxin-a in a nitrogen-fixing cyanobacterium.
    Authors: Gagnon and Pick
    Front Microbiol  2012;3:211

FAQs

  1. Why is fumarate included in the formulation?

    • Fumarate salt confers water solubility of the (±)-Anatoxin A.

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