Alprostadil
Chemical Name: (11α,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid
Purity: ≥98%
Biological Activity
Alprostadil is a prostaglandin with some selectivity for EP3 and EP4 receptors (Ki values are 1.1, 2.1, 36, 10 and 33 nM for mouse EP3, EP4, EP1, EP2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
Kiriyama et al.
Br.J.Pharmacol., 1997;122:217 -
Prostaglandin E1: a review.
Kirtland
Prostaglandins Leukot.Essent.Fatty Acids, 1988;32:165 -
Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets.
Whittle et al.
Adv.Exp.Med.Biol., 1985;192:109
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for Alprostadil
The citations listed below are publications that use Tocris products. Selected citations for Alprostadil include:
1 Citation: Showing 1 - 1
-
Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression.
Authors: Bisikirska Et al.
Cancer Res 2016;76:664
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Alprostadil
There are currently no reviews for this product. Be the first to review Alprostadil and earn rewards!
Have you used Alprostadil?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
