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AdipoRon hydrochloride

Catalog #: 5096
1 Citation Datasheet / COA / SDS
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5096/10
5096/50
AdipoRon hydrochloride | CAS No. 1781835-20-8 | Additional Peptide Receptor Products
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Description: Orally active AdipoR1 and AdipoR2 agonist; antidiabetic

Chemical Name: 2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

AdipoRon hydrochloride is an agonist of adiponectin receptors AdipoR1 and AdipoR2 (Kd values are 1.8 and 3.1 μM respectively). Activates AMPK and PPARα signaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance in db/db mice. Orally active antidiabetic agent.

Technical Data

M.Wt:
464.98
Formula:
C27H28N2O3.HCl
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1781835-20-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
    Okada-Iwabu et al.
    Nature, 2013;503:493

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Citation for AdipoRon hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for AdipoRon hydrochloride include:

1 Citation: Showing 1 - 1

  1. Iron induces ins. resistance in cardiomyocytes via regulation of oxidative stress.
    Authors: Sung Et al.
    Sci Rep  2019;9:4668

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