A 85380 dihydrochloride

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5017/10
A 85380 dihydrochloride | CAS No. 174740-86-4 | Nicotinic (a4b2) Receptor Agonists
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Description: High affinity and selective α4β2 nAChR agonist

Chemical Name: 3-[(2S)-2-Azetidinylmethoxy]-pyridine dihydrochloride

Purity: ≥98%

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Biological Activity

A 85380 dihydrochloride is a high affinity and selective α4β2 nACh receptor agonist (Ki values are 0.05, 148 and 314 nM for α4β2, α7 and α1β1δγ receptors respectively). Stimulates cation efflux in K177 cells expressing α4β2.

Technical Data

M.Wt:
237.13
Formula:
C9H12N2O.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
174740-86-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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