A 85380 dihydrochloride
Chemical Name: 3-[(2S)-2-Azetidinylmethoxy]-pyridine dihydrochloride
Purity: ≥98%
Biological Activity
A 85380 dihydrochloride is a high affinity and selective α4β2 nACh receptor agonist (Ki values are 0.05, 148 and 314 nM for α4β2, α7 and α1β1δγ receptors respectively). Stimulates cation efflux in K177 cells expressing α4β2.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.
Abreo et al.
J.Med.Chem., 1996;39:817 -
A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand.
Sullivan et al.
Neuropharmacology, 1996;35:725
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for A 85380 dihydrochloride
There are currently no reviews for this product. Be the first to review A 85380 dihydrochloride and earn rewards!
Have you used A 85380 dihydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image