5-Carboxamidotryptamine maleate

Catalog # Availability Size / Price Qty
0458/10
0458/50
5-Carboxamidotryptamine maleate | CAS No. 74885-72-6 | Non-selective 5-HT1 Receptor Agonists
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Description: 5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7
Alternative Names: AH-21467,5-CT

Purity: ≥99%

Product Details
Citations (14)
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Biological Activity

5-Carboxamidotryptamine maleate is a 5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B, 5-HT1D, 5-ht5 and 5-HT7 receptors.

Technical Data

M.Wt:
319.32
Formula:
C11H13N3O.C4H4O4
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
74885-72-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for 5-Carboxamidotryptamine maleate

The citations listed below are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:

14 Citations: Showing 1 - 10

  1. Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix
    Authors: Bijata Et al.
    Cell Rep  2017;19:1767
  2. Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
    Authors: Sargin Et al.
    Elife  2016;5:e21416
  3. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
    Authors: Chan Et al.
    PLoS Pathog  2016;12:e1005651
  4. 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts.
    Authors: Chien and Su
    PLoS One  2015;22:42
  5. Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
    Authors: Montalbano Et al.
    Br J Pharmacol  2015;10:e0140369
  6. Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor.
    Authors: Gantz Et al.
    Am J Physiol Renal Physiol  2013;78:807
  7. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim Et al.
    Neuron  2013;190:4795
  8. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  9. 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo.
    Authors: Müller Et al.
    PLoS One  2009;4:e6453
  10. Serotonin targets inhibitory synapses to induce modulation of network functions.
    Authors: Manzke Et al.
    Philos Trans R Soc Lond B Biol Sci  2009;364:2589

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