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3-Bromo-7-nitroindazole

Catalog #: 0735
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0735/10
0735/50
3-Bromo-7-nitroindazole | CAS No. 74209-34-0 | nNOS Inhibitors
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Description: Selective nNOS inhibitor

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

3-Bromo-7-nitroindazole is a potent inhibitor of rat cerebellar nitric oxide synthase; more potent than 7-nitroindazole (Cat. No. 0602).

Technical Data

M.Wt:
242.03
Formula:
C7H4BrN3O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
74209-34-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. 7-Nitroindazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase.
    Bland-Ward and Moore
    Life Sci., 1995;57:PL131
  3. Isoform selectivity of indazole-based nitric oxide synthase inhibitors.
    Bland-Ward et al.
    Br.J.Pharmacol., 1994;112:351P

Product Datasheets

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Citation for 3-Bromo-7-nitroindazole

The citations listed below are publications that use Tocris products. Selected citations for 3-Bromo-7-nitroindazole include:

1 Citation: Showing 1 - 1

  1. Lactate dilates cochlear capillaries via type V fibrocyte-vessel coupling signaled by nNOS.
    Authors: Dai Et al.
    Am J Physiol Heart Circ Physiol  2011;301:H1248

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