3-Aminobenzamide
Discontinued Product
Biological Activity
3-Aminobenzamide is an inhibitor of poly(ADP-ribose) polymerase, which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion.
Cuzzocrea et al.
Br.J.Pharmacol., 1997;121:1065 -
3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion.
Malorni et al.
Biochem.Biophys.Res.Commun., 1995;207:715
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Citation for 3-Aminobenzamide
The citations listed below are publications that use Tocris products. Selected citations for 3-Aminobenzamide include:
1 Citation: Showing 1 - 1
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The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells.
Authors: Pakula Et al.
Int J Mol Sci 2019;20
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