2-Phospho-L-ascorbic acid trisodium salt
Chemical Name: 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
Purity: ≥95%
Biological Activity
2-Phospho-L-ascorbic acid trisodium salt is a stable ascorbic acid derivative used in cell culture; in combination with FGF-2, maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. Also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine (Cat. No. 5619).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
Falcon et al.
PLoS One, 2014;9:e106901 -
L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor.
Bae et al.
Growth Factors, 2015;33:71 -
Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis.
Li et al.
Sci.Rep., 2015;5:9819
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