"CCR7 Antibody" has 12 results in Resources.

CCR7 CCR7, an orphan receptor formerly known as EBI1 (EBV-induced gene 1),1 is the chemokine receptor for CCL19/ELC/MIP-3 beta and CCL21/SLC/6Ckine.2-4 It is expressed on T cells and dendritic cells (DC), consistent with the chemotactic action of CCL19 and CCL21 for both lymphocytes and mature DC. Both memory (CD45RO+) and naïve (CD45RA+) CD4+ and CD8+ T cells express the CCR7 receptor.5 Within...

Chemokine receptors and other multipass proteins require special consideration when staining live cells for flow cytometry analysis. These receptors have seven transmembrane domains, all of which are fluid and moving around in the cell membrane. As a result, the three extracellular loops, to which antibodies must bind, are also moving and this motion can change the orientation of antibody...

Evidence is starting to suggest that memory T cells may be the most potent and effective subset to use for T cell therapy. Take advantage of the quality and selection of R&D Systems® and Novus Biologicals® antibodies to identify memory T cell subsets by flow cytometry. Refer to the tables below for the phenotypes of human and mouse memory T cell subsets and our selection of relevant flow...

Peridinin Chlorophyll Protein Complex (PerCP)-conjugated antibod­ies are convenient tools for use in flow cytometry experiments. PerCP is a water soluble carotenoid pigment found in photosynthetic dino­flagellates. It is excited by a 488 nm argon laser, and with a relatively large Stokes shift, emits at a maximum wavelength of 675 nm. Be­cause of these spectral characteristics, there is...

Bio-Techne’s Go Everywhere Travel Grant Program awards $1000 USD (or equivalent) to one researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration. The recipient of the March 2019 grant...

Expand your dendritic cell (DC) cultures with our CellXVivo™ Human Monocyte-derived DC Differentiation Kit with an optimized protocol and optimized reagents. Or you can use our specially-designed StemXVivo® Serum-Free Dendritic Cell Base Media supplemented with our high-quality recombinant Cytokines and Growth Factors. For DC vaccine preparation with more rigorous documentation, take advantage...

Flow cytometry is a powerful technique that allows researchers to examine multiple proteins on cell populations using fluorescently labeled antibodies. Multi-parameter fluidic-based flow cytometry has been applied to multiple fields of study ranging from basic to clinical immunology, cancer biology, neuroscience, stem cell research and drug discovery. In order to maximize the quality of results...

Committed to providing high quality research reagents in the formats and quantities researchers need, R&D Systems has introduced a 25-test size of our fluorochrome-conjugated chemokine receptor antibodies. This new smaller size is an ideal option for researchers conducting pilot flow cytometry experiments or trial testing of an antibody. For ease of use and storage, the 25-test size flow...

First Published in R&D Systems' 2006 Catalog Contents Multiple Sclerosis Etiology Pathology Blood-Brain Barrier Adhesion Molecules Tight Junctions Selectins Ig Superfamily Cell Adhesion Molecules ICAM-1 VCAM-1 PECAM-1 Integrins alphaLbeta2/LFA-1 alpha4beta1/VLA-4 Chemokines Chemokine Receptors Matrix Metalloproteinases MMP-9 Conclusion Multiple sclerosis...

First printed in R&D Systems' 2000 Catalog. Overview Immunity is the result of interplay between two "immune" systems: the innate immune system that initially encounters antigen and the adaptive immune system of T and B cells, which responds to information provided by the innate system. A hallmark of the innate system is the non-specificity of antigen identification. By utilizing a relatively...